The exact duration for taking Combutol 1000 and Oflomac 400 depends entirely on your specific type of tuberculosis (drug-sensitive or drug-resistant) and your doctor's protocol. Typically, Combutol (Ethambutol) is used during the intensive phase of TB treatment, which usually lasts for 2 months. Oflomac (Ofloxacin) is a second-line drug often used for drug-resistant TB, where the course can extend from 9 to 24 months. Because TB regimens are highly personalized, you must strictly follow the exact duration prescribed by your pulmonologist. Never stop these medications early, as incomplete treatment can lead to dangerous drug resistance.