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Composition : EBASTINE-10MG
Dose Form : TABLET
Description : EBASIL 10MG TAB
Route Of Administration : ORAL
Pack : 10

Drug Ingredient Information



Information for patients
Drug Information Ebastine is a long-acting and selective H1-histamine receptor antagonist. After repeated administration, inhibition of peripheral receptors remain at a constant level. Ebastine is indicated for the symptomatic treatment of: •Seasonal and perennial allergic rhinitis •Idiopathic chronic urticaria
Drug Alert
Alert It is advisable to exercise caution when using Kestine in patients known to have the following conditions: long QT syndrome, hypokalaemia, treatment with any medicine known to produce an increase in QT interval or inhibit CYP3A4 enzyme systems such as azole antifungals and macrolide antibiotics (refer to section on "Interactions").
Before Consuming the Medicine
Avoid Drug Patients with a known hypersensitivity to ebastine or any of its ingredients. The safety of ebastine during pregnancy and lactation has not been established. The safety and efficacy of ebastine tablets in children less than 12 years has not been established.
Drug Special Care no data available
Drug Drug Interactions The interaction of ebastine in combination with either ketoconazole or erythromycin (both known to prolong the QTc interval) has been evaluated. A significant pharmacokinetic and pharmacodynamic interaction has been observed with these combination; an 18-19 msec (4,7% - 5%) increase in QTc has been reported with either combination. Ebastine does not interact with the kinetics of theophylline, warfarin, cimetidine, diazepam or alcohol. The sedation effect of alcohol and diazepam may be enhanced. When ebastine is administered with food, there is a 1,5 to 2,0 fold increase in the plasma levels and the AUC of the main active acid metabolite of ebastine. This increase does not alter the Tmax. The administration of ebastine with food does not cause a modification in its clinical effect. Ebastine lacks significant sedative effects. Patients should, however, be warned that a small number of individuals may experience sedation. It is therefore advisable to determine individual response before driving or performing complicated tasks. This effect may be compounded by the simultaneous intake of alcohol or other central nervous system depressants.
Drug Pregnancy Interaction no data available
Drug Breast feeding Interaction no data available
Drug Machinery Interaction no data available
Drug More Information no data available
How to take the Medicine
Consumption Info no data available
Drug quanitty Allergic rhinitis 10 mg (one tablet) once a day Idiopathic chronic urticaria 10 mg (one tablet) once a day. Ebastine may be taken with or without food.
Drug Dose no data available
Excess Drug Consumption In studies conducted at a high dosage, no clinically meaningful signs or symptoms were observed up to 100 mg given once daily. There is not specific antidote for ebastine. In case of accidental overdosages, gastric lavage, monitoring of vital functions including ECG, and symptomatic treatment should be carried out.
Forgot Drug Consumption Contact Your doctor
Stop Drug Consumption Do not stop the drug untill your doctor says you to do so.
Possible Side Effects
General Information no data available
Common Drug Side Effects The most common side-effects are headache, dry mouth and drowsiness. Other less commonly reported side effects include pharyngitis, abdominal pain, dyspepsia, asthenia, epistaxis, rhinitis, sinusitis, nausea and insomnia.
Rare Drug Side Effects no data available
Very Rare Drug Side Effects no data available
Drug Side Effects Symptoms no data available
How to Store the Medicine
How to Store the Medicine Store below 25°C. Protect from light. KEEP OUT OF REACH OF CHILDREN.

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