EUREPA 2MG MF TABLET

In stock
SKU
EUR0028
₹218.60 Inclusive of all taxes
Manufacturer : TOR-TORRENT PHARMA LTD
Composition : REPAGLINIDE-2MG+METFORMIN-500MG
Dose Form : TABLET
Description : EUREPA 2 MF TAB
Route Of Administration : ORAL
Pack : 1

Drug Ingredient Information

REPAGLINIDE-2MG+METFORMIN-500MG

REPAGLINIDE

Information for patients
Drug Information Repaglinide are an oral antidiabetic agent containing repaglinide which helps your pancreas produce more insulin and thereby lower your blood sugar (glucose). Type 2 diabetes is a disease in which your pancreas does not make enough insulin to control the sugar in your blood or where your body does not respond normally to the insulin it produces (formerly known as non-insulin-dependent diabetes mellitus or maturity onset diabetes) Repaglinide is used to control type 2 diabetes as an add-on to diet and exercise: treatment is usually started if diet, exercise and weight reduction alone have not been able to control (or lower) your blood sugar. Repaglinide can also be given with metformin, another medicine for diabetes.
Drug Alert
Alert no data available
Before Consuming the Medicine
Avoid Drug • if you are hypersensitive (allergic) to repaglinide or any of the other components of the medicine; • if you have type 1 diabetes (insulin-dependent diabetes); • if the acid level in your body is raised (diabetic ketoacidosis); • if you have a severe liver disease; •if you take gemfibrozil (a medicine used to lower increased fat levels in the blood). If any of these apply to you, tell your doctor and do not take Repaglinide .
Drug Special Care •if you have liver problems. Repaglinide is not recommended in patients with moderate liver disease. Repaglinide should not be taken if you have a severe liver disease (see Do not take Repaglinide ); •if you have kidney problems. Repaglinide should be taken with caution; •if you are about to have major surgery or you have recently suffered a severe illness or infection. At such times diabetic control may be lost; •if you are under 18 or over 75 years of age. Repaglinide is not recommended. It has not been studied in these age groups. Talk to your doctor if any of the above applies to you. Repaglinide may not be suitable for you to use. Your doctor will advise you. If you get a hypo You may get a hypo (short for a hypoglycaemic reaction and is a symptom of low blood sugar) if your blood sugar gets too low. This may happen: • if you take too much Repaglinide; • if you exercise more than usual; • if you take other medicines or suffer from liver or kidney problems. The warning signs of a hypo may come on suddenly and can include: cold sweat; cool pale skin; headache; rapid heart beat; feeling sick; feeling very hungry; temporary changes in vision; drowsiness; unusual tiredness and weakness; nervousness or tremor; feeling anxious; feeling confused; difficulty in concentrating. If your blood sugar is low or you feel a hypo coming on: eat glucose or a high sugar snack or drink, then rest. When symptoms of hypoglycaemia have disappeared or when blood sugar levels are stabilised continue Repaglinide treatment. Tell people you have diabetes and that if you pass out (become unconscious) due to a hypo, they must turn you on your side and get medical help straight away. They must not give you any food or drink. It could choke you. • If severe hypoglycaemia is not treated, it can cause brain damage (temporary or permanent) and even death. • If you have a hypo that makes you pass out, or a lot of hypos, talk to your doctor. The amount of Repaglinide, food or exercise may need to be adjusted. If your blood sugar gets too high Your blood sugar may get too high (hyperglycaemia). This may happen: • if you take too little Repaglinide; • if you have an infection or a fever; • if you eat more than usual; • if you exercise less than usual. The warning signs appear gradually. They include: increased urination; feeling thirsty; dry skin and dry mouth. Talk to your doctor. The amount of Repaglinide, food or exercise may need to be adjusted.
Drug Drug Interactions You can take Repaglinide with metformin, another medicine for diabetes, if your doctor prescribes it. If you take gemfibrozil (used to lower increased fat levels in the blood) you should not take Repaglinide. Your body’s response to Repaglinide may change if you take other medicines, especially these: • Gemfibrozil (used to treat high blood fats) •Monoamine oxidase inhibitors (MAOI) (used to treat depression) • Beta blockers (used to treat high blood pressure or heart conditions) • ACE-inhibitors (used to treat heart conditions) • Salicylates (e.g. aspirin) • Octreotide (used to treat cancer and acromegaly) • Nonsteroidal anti-inflammatory drugs (NSAID) (a type of painkiller) • Steroids (anabolic steroids and corticosteroids – used for anaemia or to treat inflammation) • Oral contraceptives (birth control pills) •Thiazides (diuretics or “water pills”, used to treat high blood pressure and oedema) •Danazol (used to treat breast cysts and endometriosis) •Thyroid products (used to treat patients with low levels of thyroid hormones) • Sympathomimetics (used to treat asthma) • Ketoconazole, itraconazole (antifungal medicines) •Trimethoprim, clarithromycin, rifampicin (antibacterial medicines) • Ciclosporin (used to suppress the immune system) • Phenytoin, carbamazepine, phenobarbital (used to treat epilepsy) • St. John’s wort (herbal medicine)
Drug Pregnancy Interaction You should not take Repaglinide if you are pregnant or you are planning to become pregnant. See your doctor as soon as possible if you become pregnant or are planning to become pregnant during treatment. You should not take Repaglinide if you are breast-feeding.
Drug Breast feeding Interaction You should not take Repaglinide if you are pregnant or you are planning to become pregnant. See your doctor as soon as possible if you become pregnant or are planning to become pregnant during treatment. You should not take Repaglinide if you are breast-feeding.
Drug Machinery Interaction Your ability to drive or operate a machine may be affected if your blood sugar is low or high. Bear in mind that you could endanger yourself or others. Please ask your doctor whether you can drive a car if you: • have frequent hypos; • have few or no warning signs of hypos.
Drug More Information Take Repaglinide before main meals. Alcohol can change the ability of Repaglinide to reduce the blood sugar. Watch for signs of a hypo.
How to take the Medicine
Consumption Info no data available
Drug quanitty • The dose may be adjusted by your doctor up to 4mg to be taken immediately before or up to 30 minutes before each main meal. The maximum recommended daily dose is 16mg.
Drug Dose Your doctor will work out your dose. • The normal starting dose is 0.5mg before each main meal. Swallow the with a glass of water immediately before or up to 30 minutes before each main meal. Do not take more Repaglinide than your doctor has recommended. Always use Repaglinide exactly as your doctor has told you. Check with your doctor if you are not sure.
Excess Drug Consumption If you take more of antidiabetic agents than you should, your blood sugar may become too low leading to a hypo. Please see If you get a hypo on what a hypo is and how to treat it.
Forgot Drug Consumption If you miss a dose, take the next dose as usual – do not double the dose.
Stop Drug Consumption Be aware that the desired effect is not achieved if you stop taking Repaglinide. Your diabetes may get worse. If any change of your treatment is necessary contact your doctor first.
Possible Side Effects
General Information no data available
Common Drug Side Effects • Hypoglycaemia (see If you get a hypo). The risk of getting a hypo may increase if you take other medicine; • Stomach pain; • Diarrhoea.
Rare Drug Side Effects • Acute coronary syndrome (but it may not be due to the drug).
Very Rare Drug Side Effects • Allergy (such as swelling, difficulty in breathing, rapid heart beat, feeling dizzy, sweating, which could be signs of anaphylactic reaction). Contact a doctor immediately; • Vomiting; • Constipation; • Visual disturbances; • Severe liver problems, abnormal liver function, increased liver enzymes in your blood.
Drug Side Effects Symptoms • Hypoglycaemic coma or unconsciousness (very severe hypoglycaemic reactions – see If you get a hypo). Contact a doctor immediately; • Hypersensitivity (such as rash, itchy skin, reddening of the skin, swelling of the skin); • Feeling sick (nausea).
How to Store the Medicine
How to Store the Medicine Keep out of the reach and sight of children. This medicinal product does not require any special storage precautions. Do not use after the expiry date, which is stated on the outer carton, container and the blister after “EXP.” The expiry date refers to the last day of that month. Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.

METFORMIN

Information for patients
Drug Information Metformin is used alone or with other medications, including insulin, to treat type 2 diabetes (condition in which the body does not use insulin normally and, therefore, cannot control the amount of sugar in the blood). Metformin helps to control the amount of glucose (sugar) in your blood. It decreases the amount of glucose you absorb from your food and the amount of glucose made by your liver. Metformin also increases your body's response to insulin, a natural substance that controls the amount of glucose in the blood. Metformin is not used to treat type 1 diabetes (condition in which the body does not produce insulin and therefore cannot control the amount of sugar in the blood).
Drug Alert
Alert no data available
Before Consuming the Medicine
Avoid Drug Tell your doctor if you regularly drink alcohol or sometimes drink large amounts of alcohol in a short time (binge drinking). Drinking alcohol increases your risk of developing lactic acidosis or may cause a decrease in blood sugar. Ask your doctor how much alcohol is safe to drink while you are taking metformin.
Drug Special Care Before taking metformin, tell your doctor and pharmacist if you are allergic to metformin or any other medications. tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking. Be sure to mention the medications listed in the IMPORTANT WARNING section and any of the following: amiloride (Midamor, Moduretic); antihistamines; beta-blockers such as atenolol (Tenormin), labetalol (Normodyne), metoprolol (Lopressor, Toprol XL), nadolol (Corgard), and propranolol (Inderal); calcium channel blockers such as amlodipine (Norvasc), diltiazem (Cardizem, Dilacor, Tiazac, others), felodipine (Lexxel, Plendil), isradipine (DynaCirc), nicardipine (Cardene), nifedipine (Adalat, Procardia), nimodipine (Nimotop), nisoldipine (Sular), and verapamil (Calan, Isoptin, Verelan); cimetidine (Tagamet); digoxin (Lanoxin, Lanoxicaps); furosemide (Lasix); hormone replacement therapy; insulin or other medications for diabetes; isoniazid (INH, Nydrazid); medications for asthma and colds; medications for mental illness and nausea such as fluphenazine (Prolixin), mesoridazine (Serentil), perphenazine (Trilafon), prochlorperazine (Compazine), promethazine (Phenergan), thioridazine (Mellaril), thiothixene (Navane), trifluoperazine (Stelazine), and triflupromazine (Vesprin); medications for thyroid disease; morphine (MS Contin, Roxanol, others); nicotinic acid; oral contraceptives ('birth control pills'); oral steroids such as dexamethasone (Decadron, Dexone), methylprednisolone (Medrol), and prednisone (Deltasone); phenytoin (Dilantin, Phenytek); procainamide (Procanbid); quinidine (Quinidex); quinine; ranitidine (Zantac); triamterene (Dyazide, Maxzide, others); or trimethoprim (Proloprim, Trimpex). Your doctor may need to change the doses of your medications or monitor you carefully for side effects. tell your doctor if you have or have ever had any medical condition, especially those mentioned in the IMPORTANT WARNING section. tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking metformin, call your doctor. if you are using the extended-release tablets, you should know that sometimes the tablet shell may appear in your stool. If this occurs, it is not harmful and will not affect the way the medication works. tell your doctor if you eat less or exercise more than usual. This can affect your blood sugar. Your doctor will give you instructions if this happens.
Drug Drug Interactions acyclovir (Zovirax); acetaminophen (Tylenol); aminoglycoside antibiotics such as amikacin (Amikin), gentamicin (Garamycin), Kanamycin (Kantrex), Neomycin (Neo-Fradin, Neo-Rx), netilmicin (Netromycin), paromomycin (Humatin), streptomycin and tobramycin (Nebcin, Tobi); amphotericin B (Abelcet, Amphocin, others); angiotensin converting enzyme (ACE) inhibitors such as benazepril (Lotensin), captopril (Capoten), enalapril (Vasotec), fosinopril (Monopril), lisinopril (Prinvil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), ramipril (Altace), and trandolapril (Mavik); aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Advil, Motrin) and naproxen (Aleve, Naprosyn); cancer chemotherapy medications; cyclosporine (Sandimmune, Neoral); dapsone (Avlosulfon); diuretics (water pills); foscarnet (Foscavir); gold compounds such as auranofin (Ridaura), aurothioglucose (Aurolate, Solganol), and gold sodium thiomalate (Myochrysine); hydralazine (Hydra-Zide); lithium (Eskalith, Lithobid); medications to treat human immunodeficiency virus (HIV) or acquired immunodeficiency syndrome (AIDS); methicillin (Staphcillin); nitrates; penicillin and sulfa antibiotics; penicillamine (Cuprimine, Depen); primaquine; propranolol (Inderal); rifampin (Rifadin, Rimactane); tacrolimus (Prograf); vancomycin (Vancocin); or if you have ever taken the Chinese weight-loss herb Aristolochia.
Drug Pregnancy Interaction no data available
Drug Breast feeding Interaction no data available
Drug Machinery Interaction no data available
Drug More Information In addition to describing the cardiovascular risks, the drug labels have been revised to state that rosiglitazone and rosiglitazone-containing medicines should only be used: In patients already being treated with these medicines In patients whose blood sugar cannot be controlled with other anti-diabetic medicines and who, after consulting with their healthcare professional, do not wish to use pioglitazone-containing medicines
How to take the Medicine
Consumption Info If you are having surgery, including dental surgery, any x-ray procedure in which dye is injected, or any major medical procedure, tell the doctor that you are taking metformin. You may need to stop taking metformin before the procedure and wait 48 hours to restart treatment. Your doctor will tell you exactly when you should stop taking metformin and when you should start taking it again.
Drug quanitty no data available
Drug Dose Metformin comes as a liquid, a tablet and an extended-release (long-acting) tablet to take by mouth. The liquid is usually taken with meals one or two times a day. The regular tablet is usually taken with meals two or three times a day. The extended-release tablet is usually taken once daily with the evening meal. To help you remember to take metformin, take it around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take metformin exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Swallow metformin extended-release tablets whole; do not split, chew, or crush them. Your doctor may start you on a low dose of metformin and gradually increase your dose not more often than once every 1 to 2 weeks. You will need to monitor your blood sugar carefully so your doctor will be able to tell how well metformin is working. Metformin controls diabetes but does not cure it. Continue to take metformin even if you feel well. Do not stop taking metformin without talking to your doctor.
Excess Drug Consumption In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911. Symptoms of overdose may include: extreme tiredness weakness discomfort vomiting nausea stomach pain decreased appetite deep, rapid breathing shortness of breath dizziness lightheadedness abnormally fast or slow heartbeat flushing of the skin muscle pain feeling cold
Forgot Drug Consumption Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
Stop Drug Consumption Do not stop the drug untill your doctor says you to do so.
Possible Side Effects
General Information extreme tiredness, weakness, or discomfort; nausea; vomiting; stomach pain; decreased appetite; deep and rapid breathing or shortness of breath; dizziness; lightheadedness; fast or slow heartbeat; flushing of the skin; muscle pain; or feeling cold.
Common Drug Side Effects Metformin may rarely cause a serious, life-threatening condition called lactic acidosis. Tell your doctor if you have or have ever had a heart attack; stroke; high blood pressure; diabetic ketoacidosis (blood sugar that is high enough to cause severe symptoms and requires emergency medical treatment) or coma; surgery to remove part of your small intestine; anemia (not enough red blood cells), or heart, kidney, lung, or liver disease.
Rare Drug Side Effects no data available
Very Rare Drug Side Effects no data available
Drug Side Effects Symptoms This medication may cause changes in your blood sugar. You should know the symptoms of low and high blood sugar and what to do if you have these symptoms. You may experience hypoglycemia (low blood sugar) while you are taking this medication. Your doctor will tell you what you should do if you develop hypoglycemia. He or she may tell you to check your blood sugar, eat or drink a food or beverage that contains sugar, such as hard candy or fruit juice, or get medical care. Follow these directions carefully if you have any of the following symptoms of hypoglycemia: shakiness dizziness or lightheadedness sweating nervousness or irritability sudden changes in behavior or mood headache numbness or tingling around the mouth weakness pale skin hunger clumsy or jerky movements If hypoglycemia is not treated, severe symptoms may develop. Be sure that your family, friends, and other people who spend time with you know that if you have any of the following symptoms, they should get medical treatment for you immediately: confusion seizures loss of consciousness Call your doctor immediately if you have any of the following symptoms of hyperglycemia (high blood sugar): extreme thirst frequent urination extreme hunger weakness blurred vision If high blood sugar is not treated, a serious, life-threatening condition called diabetic ketoacidosis could develop. Call your doctor immediately if you have any of these symptoms: dry mouth nausea and vomiting shortness of breath breath that smells fruity decreased consciousness Metformin may cause side effects. Tell your doctor if any of these symptoms are severe, do not go away, go away and come back, or do not begin for some time after you begin taking metformin: diarrhea bloating stomach pain gas constipation unpleasant metallic taste in mouth heartburn headache sneezing cough runny nose flushing of the skin nail changes muscle pain Some side effects can be serious. The following symptoms are uncommon, but if you experience any of them or those listed in the IMPORTANT WARNING section, call your doctor immediately: chest pain rash Some female laboratory animals given high doses of metformin developed non-cancerous polyps (abnormal growths of tissue) in the uterus (womb). It is not known if metformin increases the risk of polyps in humans. Talk to your doctor about the risks of taking this medication. Metformin may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
How to Store the Medicine
How to Store the Medicine Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from light excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

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