|Information for patients
Felodipine tablets belong to a group of medicines called dihydropyridine-type calcium channel blockers. These work by relaxing the smooth muscle in the blood vessel walls and opening the blood vessels. This then lowers the blood pressure. Felodipine tablets are used to treat patients with high blood pressure (hypertension). High blood pressure often causes no symptoms, but if it is not treated it can damage blood vessels in the long-term. In some cases this can lead to heart attacks, kidney failure, stroke or blindness. That is why it is important not to stop taking this medicine without talking to your doctor.
|Before Consuming the Medicine
||•are allergic (hypersensitive) to felodipine, other similar compounds.
•have a very low pulse and blood pressure (cardiogenic shock)
•have severe narrowing (stenosis) of the aorta or of the heart valves (mitral or aortic valve)
•suffer from an enlarged heart muscle (hypertrophic cardiomyopathy)
•get chest pain caused by coronary heart disease also at rest or with minimal effort (so called unstable angina pectoris)
•have suffered a heart attack within the last two months
•have untreated heart failure, causing swelling of the extremities, weakness, and shortness of breath
•have severely reduced liver function
•are or may be pregnant (see “Pregnancy” below).
|Drug Special Care
||•have severely reduced kidney function
•have reduced liver function
•suffer with stable heart failure
•suffer with fast heart beat (tachycardia)
•suffer with narrowing (stenosis) of the aorta or of the heart valves (mitral or aortic valve)
•have conduction disturbances in the heart (2nd or 3rd degree atrioventricular block)
|Drug Drug Interactions
||•other medicines that lower blood pressure such as hydrochlorothiazide, beta blockers (to treat high blood pressure), nitrates (to control coronary heart disease and chest pain), tricyclic antidepressants (to treat depression) or phenothiazines (to treat psychoses)
•amiodarone, diltiazem or verapamil (to treat heart problems)
•digoxin (to treat heart failure)
•fluconazole, itraconazole, ketoconazole, miconazole, or voriconazole (to treat fungal or yeast infections)
•erythromycin, clarithromycin, or telithromycin (antibiotics)
•rifampicin or rifabutin (to treat tuberculosis)
•fluoxetine or fluovoxamine (to treat depression)
•ciclosporin (to suppress immune system e.g. after organ transplantation)
•phenobarbital, phenytoin, or carbamazepine (to treat epilepsy)
•cimetidine (to treat heartburn and stomach ulcers)
•nevirapine, ritonavir, sakinavir (to treat HIV infection)
•herbal medicines containing St. John’s wort (Hypericum perforatum).
|Drug Pregnancy Interaction
||Felodipine must not be taken during the whole pregnancy. If you think you are pregnant, plan to get pregnant or become pregnant while using felodipine tablets stop using the medicine immediately and consult the doctor as soon as possible.
|Drug Breast feeding Interaction
||Felodipine is excreted in breast milk, therefore the use of felodipine tablets is not recommended while breastfeeding. Ask your doctor or pharmacist for advice before taking any medicine.
|Drug Machinery Interaction
||Felodipine tablets can cause dizziness or tiredness. These effects are more likely to occur at the start of treatment, after dose increases, or after taking alcohol at the same time. If you are affected, do not drive or operate machinery.
|Drug More Information
|How to take the Medicine
||Adult: Initially, 1 tablet (5mg) once daily. If needed, the doctor may increase the dose to 2 tablets (10mg) daily or may prescribe an additional medicine to lower blood pressure.
Elderly: The doctor will decide your starting dose.
Children: Not recommended.
Kidney and/or liver problems: patients with severe liver problems must not take Vascalpha tablets and patients with
severe kidney problems should not take felodipine tablets.
If you have liver disease, your doctor will monitor your condition and may prescribe you a smaller dose.
||•Swallow these tablets whole at the same time of the day (e.g. in the morning) with a glass of water. Do not crush or chew
•Do not take with grapefruit juice, as this may make felodipine tablets work too strongly.
•Take the tablets on an empty stomach or with a light meal. The tablets should not be taken with a high fat meal.
•Take this medicine for as long as your doctor tells you to. It may be dangerous to stop without your doctor’s advice.
|Excess Drug Consumption
||Do not take more tablets than your doctor tells you to. If you ever take too many go to the nearest hospital casualty department or tell your doctor immediately. Take the container and any remaining tablets with you to show to the doctor. An overdose may lead to light-headedness, fainting and dizziness caused by very low blood pressure and in rare cases slowed heartbeat (bradycardia).
|Forgot Drug Consumption
||If you forget to take a dose, take one as soon as you remember. Then go on as before. Do not take two doses at the same time to make up for a forgotten dose. If you are worried, ask your pharmacist or doctor for advice.
|Stop Drug Consumption
||Do not stop treatment early because felodipine can be associated with withdrawal symptoms. If you stop taking the tablets too quickly you may develop high blood pressure again. Talk to your doctor before you stop taking the tablets and follow the advice.
|Possible Side Effects
||headache, tinnitus (ringing or buzzing in the ears), or flushing – these effects are more likely to occur at the start of treatment or after dose increases and may settle with continued use
|Common Drug Side Effects
||chest pain or worsening of chest pain (angina pectoris) more likely after beginning of treatment, swelling of extremities (in particular the ankles).
|Rare Drug Side Effects
||purple colouration of the skin.pins and needles’, dizziness, fatigue, restlessness, palpitations, fast heart beat (tachycardia), very low blood pressure, fainting, shortness of breath, feeling sick (nausea) or being sick (vomiting), diarrhoea, constipation, itching skin, hives (urticaria), rash, sensitivity to light, increased sweating, inflammation or swelling of the gums, joint or muscle pain, tremors, increased need to pass urine, weight gain
|Very Rare Drug Side Effects
||heart attack, liver function problems seen as raised transaminase levels in blood tests, scaling skin reactions (exfoliative dermatitis), erection disorders, enlargement of breast tissue in males, heavy menstruation, fever.
|Drug Side Effects Symptoms
|How to Store the Medicine
|How to Store the Medicine
||Keep out of the reach and sight of children. Do not store the tablets above 25°C. Do not use felodipine tablets after the expiry date which is stated on the carton and blister. The expiry date refers to the last day of that month. Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.