|Information for patients
raloxifene belongs to a group of non-hormonal medicines called Selective Oestrogen Receptor Modulators (SERMs). When a woman reaches the menopause, the level of the female sex hormone oestrogen goes down. EVISTA mimics some of the helpful effects of oestrogen after the menopause.
raloxifene is used to treat and prevent osteoporosis in postmenopausal women. EVISTA reduces the risk of vertebral fractures in women with postmenopausal osteoporosis. A reduction in the risk of hip fractures has not been shown.
Osteoporosis is a disease that causes your bones to become thin and fragile - this disease is especially common in women after the menopause. Although it may have no symptoms at first, osteoporosis makes you more likely to break bones, especially in your spine, hips and wrists and may cause back pain, loss of height and a curved back.
|Before Consuming the Medicine
||If you are allergic (hypersensitive) to raloxifene or any of the ingredients of raloxifene .
If there is still a possibility that you can get pregnant, raloxifene could harm your unborn child.
If you are being treated or have been treated for blood clots (deep vein thrombosis, pulmonary embolism or retinal vein thrombosis).
If you have liver disease (examples of liver disease include cirrhosis, mild hepatic impairment or cholestatic jaundice).
If you have any unexplained vaginal bleeding. This must be investigated by your doctor.
If you have active uterine cancer, as there is insufficient experience of raloxifene use in women with this disease.
If you have severe kidney problems.
|Drug Special Care
||The following are reasons why this product may not be suitable for you. If any of them apply to you, talk to your doctor before you take the medicine.
If you are immobilised for some time such as being wheel-chair bound, needing to be admitted to a hospital or having to stay in bed while recovering from an operation or an unexpected illness.
If you are receiving oral oestrogen therapy.
If you are suffering from breast cancer, as there is insufficient experience of raloxifene use in women with this disease.
If you have had a cerebrovascular accident (e.g. stroke), or if your doctor has told you that you are at high risk of having one.
It is unlikely that raloxifene will cause vaginal bleeding. So any vaginal bleeding while you take raloxifene is unexpected. You should have this investigated by your doctor.
raloxifene does not treat postmenopausal symptoms, such as hot flushes.
raloxifene lowers total cholesterol and LDL ("bad") cholesterol. In general, it does not change triglycerides or HDL ("good") cholesterol. However, if you have taken oestrogen in the past and had extreme elevations in triglycerides, you should talk to your doctor before taking raloxifene .
|Drug Drug Interactions
||Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.
If you are taking digitalis medicines for your heart or anticoagulants like warfarin to thin your blood, your doctor may need to adjust your dose of these medicines.
Tell your doctor if you are taking cholestyramine which is mainly used as lipid-lowering medicine.
|Drug Pregnancy Interaction
||raloxifene is for use only by postmenopausal women and must not be taken by women who could still have a baby. raloxifene could harm your unborn child.
|Drug Breast feeding Interaction
||Do not take raloxifene if you are breast-feeding as it might be excreted in mother's milk.
|Drug Machinery Interaction
||raloxifene has no known effects on driving or using machines.
|Drug More Information
|How to take the Medicine
||Always take this product exactly as your doctor has told you. You should check with your doctor or pharmacist if you are not sure.
The dose is one tablet a day. It does not matter what time of day you take your tablet but taking the tablet at the same time each day will help you remember to take it. You may take it with or without food.
The tablets are for oral use.
Swallow the tablet whole. If you wish you may take a glass of water with it.
Your doctor will tell you how long you should continue to take raloxifene . The doctor may also advise you to take calcium and vitamin D supplements.
|Excess Drug Consumption
||Tell your doctor or pharmacist.
|Forgot Drug Consumption
||Take a tablet as soon as you remember and then continue as before.
|Stop Drug Consumption
||You should talk to your doctor first.
If you have the impression that the effect of this product is too strong or too weak, talk to your doctor or pharmacist.
|Possible Side Effects
||Hot flushes (vasodilatation)
|Common Drug Side Effects
Swelling of hands, feet and legs (peripheral oedema)
|Rare Drug Side Effects
||Increased risk of blood clots in the legs (deep vein thrombosis)
Increased risk of blood clots in the lungs (pulmonary embolism)
Increased risk of blood clots in the eyes (retinal vein thrombosis)
Skin around the vein is red and painful (superficial vein thrombophlebitis)
|Very Rare Drug Side Effects
Gastrointestinal symptoms such as nausea, vomiting, abdominal pain and stomach upset
Increased blood pressure
Decrease in the number of the platelets in the blood
Blood clot in an artery (for example stroke)
Headache including migraine
Mild breast symptoms such as pain, enlargement and tenderness
|Drug Side Effects Symptoms
|How to Store the Medicine
|How to Store the Medicine
||Keep out of the reach and sight of children.
Do not use after the expiry date which is stated on the pack.
Store in the original package. Do not freeze.
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.