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Composition : FLUOROURACIL-5% W/W
Dose Form : CREAM
Description : FLONIDA 5% 10GM CREAM
Route Of Administration : TOPICAL
Pack : 1


Drug Ingredient Information



Information for patients
Drug Information Fluorouracil is used to treat skin conditions such as growths of the skin (keratoses) and some simple skin cancers. The active ingredient fluorouracil, belongs to a group of anti-cancer medicines. Important Information About How Fluorouracil Works Fluorouracil destroys cancerous and pre-cancerous cells, while having little effect on normal cells. When you use Fluorouracil it is likely that the area of the skin that you are treating will become red. This will probably be followed by inflammation/swelling, possibly some discomfort, skin erosion and eventually, healing. This is the expected normal response to treatment and shows that Fluorouracil is working. Sometimes the response is more sever. If your skin becomes much worse, you experience pain or if you are worried, talk to your doctor. Your doctor may prescribe you another to relieve any discomfort. After stopping treatment you may find that your skin takes one to two months to heal completely. Fluorouracil will also treat abnormalities of the skin that were previously not visible to the naked eye, and these abnormalities may become red and inflamed.
Drug Alert
Alert no data available
Before Consuming the Medicine
Avoid Drug •are allergic (hypersensitive) to fluorouracil. •are pregnant, think you may be pregnant, or are breast-feeding. •are using any medicines known as antiviral nucleosides (e.g. brivudine, sorivudine). These medicines are usually used to treat chickenpox or shingles.
Drug Special Care •are applying this around your eyelids, nose or lips, and avoid contact with the eyes or mouth. •have open cuts. Do not use this on open cuts as this can lead to too much being absorbed into the blood, which very rarely, can cause side effects. •have reduced activity/deficiency of the enzyme DPD (dihydropyrimidine dehydrogenase). Sunlight may increase the effects of Fluorouracil. ?is may result in increased skin reactions. To prevent this you must try to stay out of direct sunlight as much as possible while using the and must not use a sunlamp or sun bed.
Drug Drug Interactions Tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription. This is very important, as using more than one medicine at the same time can strengthen or weaken the effect of the medicines involved. In particular, tell your doctor if you are using: •medicines to treat chickenpox or shingles (brivudine, sorivudine) or have used them in the last 4 weeks. These medicines may increase the possibility of unwanted effects with Fluorouracil.
Drug Pregnancy Interaction Do not use Fluorouracil and tell your doctor if you are pregnant, think you might be pregnant or you are breast-feeding.
Drug Breast feeding Interaction Do not use Fluorouracil and tell your doctor if you are pregnant, think you might be pregnant or you are breast-feeding.
Drug Machinery Interaction no data available
Drug More Information no data available
How to take the Medicine
Consumption Info no data available
Drug quanitty Always use Fluorouracil exactly as your doctor has told you. You must check with your doctor or pharmacist if you are not sure. If you think that the effect of your medicine is too weak or strong, talk to your doctor. Do not change your dose without asking your doctor.If you swallow some contact your doctor, pharmacist or go to your nearest hospital straight away. If any of the following occur, wash the off using water, then contact your doctor, pharmacist or go to your nearest hospital straight away: •You get this in your eyes, nose or mouth. •Someone else accidentally uses this .
Drug Dose •Only use Fluorouracil on the skin and avoid contact with the eyes and mouth. •Apply a thin layer of the to the affected area as instructed by your doctor. •It is very important that you do not use too much and do not apply the on open cuts. This may lead to some being absorbed into the blood and, very rarely, this can cause side effects. •The is usually used once or twice a day for at least three to four weeks. •Wash your hands thoroughly after using this. •Your doctor will tell you if you need to apply a dressing to the treated skin. •Never treat an area of skin larger than 23 x 23cm (9 x 9 inches) at any one time. This area is approximately the size of a dinner plate.
Excess Drug Consumption Dail 1066. OR Contact doctor immediately
Forgot Drug Consumption If you miss a dose, apply the as soon as possible. However, if it is nearly time for your next dose, skip the missed dose and carry on as before. Do not apply a double dose to make up for the missed dose.
Stop Drug Consumption Do not stop the drug untill your doctor says you to do so.
Possible Side Effects
General Information Relating to the skin and subcutaneous tissue. Itching, redness, burning sensation, severe peeling, intense swelling or inflammation, ulceration, blistering, irritation, pain and rash.
Common Drug Side Effects •Sores which are red, round and painful. •Rash on areas other than where the was applied. •Other side effects may occur if you use too much or if you apply the to open cuts. These side effects are listed below
Rare Drug Side Effects no data available
Very Rare Drug Side Effects no data available
Drug Side Effects Symptoms --Stomach problems such as pain, cramps, diarrhoea and vomiting --swelling and soreness of the mouth and tongue --fever or feeling generally unwell.
How to Store the Medicine
How to Store the Medicine •Store Fluorouracil out of the reach and sight of children. •Do not store Fluorouracil above 30°C. •For 20 g and 40 g tubes: Once opened, use within 90 days. •Do not use Fluorouracil after the expiry date which is stated on the tube and the outer carton after “EXP”. The expiry date refers to the last day of that month. •Any unused Fluorouracil should be returned to your pharmacist for safe disposal. •Medicines must not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.

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