Jakavi 5 mg Tablet का उपयोग, फायदे ,साइड इफेक्ट,कीमत in Hindi

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Jakavi 5 mg Tablet is used in the treatment of myelofibrosis (cancer of bone marrow), polycythaemia vera (cancer of the blood), and graft-versus-host disease (GVHD, a complication of hematopoietic stem-cell transplant). It contains Ruxolitinib, which works by blocking the signals that cause cancer cells to multiply. Thereby, it helps treat myelofibrosis and polycythaemia vera. It also helps treat graft-versus-host disease by blocking the signals of the cells that cause GVHD.

Written By Santoshini Reddy G , M Pharmacy

Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

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Side effects of Jakavi 5 mg Tablet

Bruising

Anemia

Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
Consume vitamin C-rich foods as they aid iron absorption.
Limit tea, cocoa, and coffee as these can slow iron absorption.
Exercise regularly; however, do not overdo it.

Low Platelet Count

Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
If you experience severe bleeding or bruising, seek emergency medical attention immediately.

Increased Risk Of Infection Due To Low Neutrophil Count

Talk to your doctor about medicines to manage neutropenia based on the underlying cause.
Avoid contact with people who are sick.
Wash your hands regularly with soap and water.
Avoid unpasteurized dairy products.

High Cholesterol

Eat more plant based foods like vegetables, fruits and whole grains.
Reduce intake of foods containing high fat such as dairy, oil and red meat.
Exercise for at least 30 minutes 5 days a week.
Aim for weight loss and maintain healthy weight.
Quit smoking.
Control blood sugar and blood pressure.

Dizziness

Here are the 7 steps to manage Dizziness caused by medication:

Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
When standing up, do so slowly and carefully to avoid sudden dizziness.
Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

Headache

Dealing with Medication-Induced Headache:

Hydrate your body: Drink enough water to prevent dehydration and headaches.
Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
Take rest: lie down in a quiet, dark environment.
Cold or warm compresses can help reduce tension.
Stay Upright: Maintain good posture to keep symptoms from getting worse.
To treat headaches naturally, try acupuncture or massage therapy.
Over-the-counter pain relievers include acetaminophen and ibuprofen.
Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
Frequent Headaches: If you get reoccurring headaches, consult your doctor.
Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Have a query?

Drug-Drug Interactions

Drug-Drug Interactions: Inform the doctor if you are taking anti-fungal (ketoconazole, itraconazole, posaconazole, fluconazole, voriconazole), antibiotics (clarithromycin, telithromycin, ciprofloxacin, erythromycin), anti-viral (amprenavir, atazanavir, indinavir, lopinavir/ritonavir, nelfinavir, ritonavir, saquinavir), medicines to treat hepatitis C (boceprevir, telaprevir), anti-depressant (nefazodone), antacid (cimetidine), anti-epileptic (phenytoin, carbamazepine, phenobarbital), anti-TB (rifabutin, rifampicin), or herbal supplement (St. John’s wort).

Drug-Food Interactions: Grapefruit juice may increase the blood levels of Ruxolitinib. Therefore, avoid consuming grapefruit or its juice during treatment with Jakavi 5 mg Tablet unless advised by the doctor.

Drug-Disease Interactions: Inform the doctor if you have heart problems, thrombosis (blood clots), hepatitis B infection, tuberculosis, infections, high lipid levels, lung problems, low blood count or cancer.

RuxolitinibIndinavir

Severe

RuxolitinibCeritinib

Severe

Drug-Drug Interactions

RuxolitinibIndinavir

Severe

How does the drug interact with Jakavi 5 mg Tablet:
Taking Jakavi 5 mg Tablet and Indinavir may increase the blood levels and effects of Jakavi 5 mg Tablet.

How to manage the interaction:
Although taking Jakavi 5 mg Tablet and Indinavir together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as paleness, tiredness, dizziness, fainting, unusual bleeding or bruising, fever, chills, sore throat, body aches. Do not stop using any medications without consulting doctor.

RuxolitinibCeritinib

Severe

How does the drug interact with Jakavi 5 mg Tablet:
Taking Jakavi 5 mg Tablet and Boceprevir may increase the blood levels and effects of Jakavi 5 mg Tablet.

How to manage the interaction:
Although there is a possible interaction between Ceritinib and Jakavi 5 mg Tablet, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as paleness, tiredness, dizziness, fainting, unusual bleeding or bruising, fever, chills, sore throat, body aches. Do not stop using any medications without consulting doctor.

RuxolitinibBaricitinib

Severe

How does the drug interact with Jakavi 5 mg Tablet:
Coadministration of baricitinib and Jakavi 5 mg Tablet can increase the risk of developing infections.

How to manage the interaction:
Although there is an interaction, baricitinib can be taken with Jakavi 5 mg Tablet if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in your coughing fluid, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without talking to a doctor.

RuxolitinibVoriconazole

Severe

How does the drug interact with Jakavi 5 mg Tablet:
Taking Jakavi 5 mg Tablet with Voriconazole may increase the blood levels and effects of Jakavi 5 mg Tablet.

How to manage the interaction:
Although taking Voriconazole and Jakavi 5 mg Tablet together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience dizziness, fever, sore throat, body pain contact a doctor. Do not discontinue any medications without consulting a doctor.

RuxolitinibClarithromycin

Severe

How does the drug interact with Jakavi 5 mg Tablet:
Taking Clarithromycin may boost the blood levels and effects of Jakavi 5 mg Tablet.

How to manage the interaction:
Although there is a possible interaction, clarithromycin can be taken with Jakavi 5 mg Tablet if prescribed by the doctor. Consult the prescriber if you experience paleness, tiredness, dizziness, fainting, unusual bleeding or bruising, fever, chills, sore throat, or body pains. Do not stop using any medications without a doctor's advice.

RuxolitinibMibefradil

Severe

How does the drug interact with Jakavi 5 mg Tablet:
Taking Jakavi 5 mg Tablet and Mibefradil may increase the blood levels and effects of Jakavi 5 mg Tablet.

How to manage the interaction:
Although taking Jakavi 5 mg Tablet and Mibefradil together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as paleness, tiredness, dizziness, fainting, unusual bleeding or bruising, fever, chills, sore throat, body aches. Do not stop using any medications without consulting doctor.

RuxolitinibFluconazole

Severe

How does the drug interact with Jakavi 5 mg Tablet:
Co-administration of Jakavi 5 mg Tablet with Fluconazole may increase the blood levels of Jakavi 5 mg Tablet.

How to manage the interaction:
Although there is a possible interaction, Fluconazole can be taken with Jakavi 5 mg Tablet if prescribed by the doctor. Consult the doctor if you experience signs and symptoms such as paleness, tiredness, dizziness, fainting, unusual bleeding or bruising, fever, chills, sore throat, body aches, or other flu-like symptoms. Do not discontinue the medications without consulting a doctor.

RuxolitinibEdoxaban

Severe

How does the drug interact with Jakavi 5 mg Tablet:
Taking Jakavi 5 mg Tablet and edoxaban together with Jakavi 5 mg Tablet may increase the risk of bleeding.

How to manage the interaction:
Although taking Jakavi 5 mg Tablet and Edoxaban together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as any unusual bleeding or bruising, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop using any medications without consulting doctor.

RuxolitinibDelavirdine

Severe

How does the drug interact with Jakavi 5 mg Tablet:
Taking Jakavi 5 mg Tablet and Delavirdine may increase the blood levels and effects of Jakavi 5 mg Tablet.

How to manage the interaction:
Although taking Jakavi 5 mg Tablet and Delavirdine together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as paleness, weakness, dizziness, fainting, unusual bleeding or bruising, fever, chills, sore throat, body aches. Do not stop using any medications without consulting a doctor.

RuxolitinibGolimumab

Severe

How does the drug interact with Jakavi 5 mg Tablet:
Taking Jakavi 5 mg Tablet together with Golimumab may increase the risk of infections.

How to manage the interaction:
Although taking Jakavi 5 mg Tablet and Golimumab together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, loose stools, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting doctor.

Drug-Food Interactions

RUXOLITINIB-5MGGrapefruit and Grapefruit Juice

Moderate

Drug-Food Interactions

RUXOLITINIB-5MGGrapefruit and Grapefruit Juice

Moderate

Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking Grape fruit or grapefruit juice with Jakavi 5 mg Tablet may increase the blood levels of Jakavi 5 mg Tablet. Although there is a possible interaction, Jakavi 5 mg Tablet can be taken if prescribed by a doctor. Contact a doctor if you have any of the following symptoms: paleness, tiredness, dizziness, fainting, unusual bleeding or bruises, fever, chills, sore throat, body pains, or other flu-like symptoms. Do not stop taking the medication without consulting a doctor.

All Substitutes & Brand Comparisons

RX
Out of Stock
Jakavi 5mg Tablet 14's
Novartis India Ltd
₹21489
(₹1534.93 per unit)
36% CHEAPER

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