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Paraquin DS 500mg Tablet is used to treat malaria. It provides a degree of protection against malaria for individuals travelling to areas where malaria cases are prevalent. It is effective against Plasmodium vivax, Plasmodium ovale, and Plasmodium malariae. It is not effective against Plasmodium falciparum. It is occasionally used to reduce the symptoms of rheumatoid arthritis and to treat conditions such as systemic and discoid lupus erythematosus, sarcoidosis, and porphyria cutanea tarda. Paraquin DS 500mg Tablet targets malaria parasites inside red blood cells and disrupts their process of breaking down haemoglobin. This leads to the accumulation of toxic substances, which destroy the parasites and clear the infection. The common side effects of Paraquin DS 500mg Tablet include vomiting, nausea, hair loss, stomach pain, stomach upset, loss of appetite, diarrhoea and itchy skin. Most of these side effects are temporary and gradually resolve over time. However, please consult the doctor if any of these side effects persist or worsen.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Drug-Drug Interaction: Paraquin DS 500mg Tablet may cause interactions with Antibiotics (ketoconazole, erythromycin, azithromycin), Antidepressants (Doxepin), Beta blockers (sotalol), Opioid analgesics (Tramadol).

Drug-Food Interaction: Limit the consumption of grapefruit or grapefruit juice with Paraquin DS 500mg Tablet as it can significantly increase the level of Paraquin DS 500mg Tablet in the blood.

Drug-Disease Interaction: Inform your doctor if you have eye disorder (ocular toxicity), blood disease (porphyria), heart disease (arrhythmias), bone marrow suppression, ear disorder (ototoxicity), seizures, enzyme deficiency (G-6-PD deficiency), liver disease (hepatotoxicity), muscle disorder (myasthenia gravis), skin disease (psoriasis) as these conditions may cause interactions.

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