LOXICARD 2% INJECTION 5ML

Out of stock
SKU
LOX0040
₹5.25 Inclusive of all taxes
Manufacturer : NEO-NEO PHARMA
Composition : LIDOCAINE-2% W/W
Dose Form : INJECTION
Description : LOXICARD 2% 5ML INJ
Route Of Administration : PARENTERAL
Pack : 1

Drug Ingredient Information

LIDOCAINE-2% W/W

LIDOCAINE

Information for patients
Drug Information Lidocaine Injection belongs to a group of medicines called local anaesthetics. Local anaesthetics work by numbing the area of the body that they are injected into which stops pain being felt. Lidocaine Injection is used to stop pain being felt during medical investigations, operations or in labour. Lidocaine Injection can also be used to treat heartbeat disturbances, especially after heart attacks or in heart surgery
Drug Alert
Alert XYLOCAINE (lidocaine) INJECTIONS FOR INFILTRATION AND NERVE BLOCK SHOULD BE EMPLOYED ONLY BY CLINICIANS WHO ARE WELL VERSED IN DIAGNOSIS AND MANAGEMENT OF DOSE-RELATED TOXICITY AND OTHER ACUTE EMERGENCIES THAT MIGHT ARISE FROM THE BLOCK TO BE EMPLOYED AND THEN ONLY AFTER ENSURING THE IMMEDIATE AVAILABILITY OF OXYGEN, OTHER RESUSCITATIVE DRUGS, CARDIOPULMONARY EQUIPMENT AND THE PERSONNEL NEEDED FOR PROPER MANAGEMENT OF TOXIC REACTIONS AND RELATED EMERGENCIES.DELAY IN PROPER MANAGEMENT OF DOSE-RELATED TOXICITY, UNDERVENTILATION FROM ANY CAUSE AND/OR ALTERED SENSITIVITY MAY LEAD TO THE DEVELOPMENT OF ACIDOSIS, CARDIAC ARREST AND, POSSIBLY, DEATH.
Before Consuming the Medicine
Avoid Drug contraindicated : Hypovolaemia, complete heart block, Adam-Stokes syndrome, Wolff-Parkinson-White syndrome
Drug Special Care special precautions: Patient w/ pseudocholinesterase deficiency, cardiac conduction disturbances, resp depression. Hepatic and renal impairment. Elderly or debilitated patients. Pregnancy and lactation. Patient Counselling May cause temporary loss of sensation and motor activity. Monitoring Parameters Monitor CV and resp vital signs, LFTs and careful ECG observation.
Drug Drug Interactions May increase serum levels w/ cimetidine and propranolol. Increased risk of cardiac depression w/ ß-blockers and other antiarrhythmics. Additive cardiac effects w/ IV phenytoin. Hypokalaemia caused by acetazolamide, loop diuretics and thiazides may antagonise effect of lidocaine. Dose requirements may be increased w/ long-term use of phenytoin and other enzyme-inducers.
Drug Pregnancy Interaction Category B: Either animal-reproduction studies have not demonstrated a foetal risk but there are no controlled studies in pregnant women or animal-reproduction studies have shown an adverse effect (other than a decrease in fertility) that was not confirmed in controlled studies in women in the 1st trimester (and there is no evidence of a risk in later trimesters).
Drug Breast feeding Interaction It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when lidocaine HCl is administered to a nursing woman.
Drug Machinery Interaction
Drug More Information levodopa levels are decreased with St John's wort.
How to take the Medicine
Consumption Info The intramuscular injection of lidocaine HCl may result in an increase in creatine phosphokinase levels. Thus, the use of this enzyme determination, without isoenzyme separation, as a diagnostic test for the presence of acute myocardial infarction may be compromised by the intramuscular injection of lidocaine HCl.
Drug quanitty Intravenous Pulseless ventricular fibrillation or ventricular tachycardia Adult: 1-1.5 mg/kg repeated as necessary. Max: 3 mg/kg. For ventricular arrhythmias in more stable patients: Usual loading dose: 50-100 mg as an IV inj at 25-50 mg/min, may repeat once or twice up to a max of 200-300 mg in 1 hr, followed by 1-4 mg/min via continuous IV infusion. May need to reduce dose if the infusion is longer than 24 hr. Hepatic impairment: Dosage reduction may be needed. Incompatibility: Amphotericin B, sulfadiazine Na, methohexital Na, cefazolin Na, phenytoin Na, pantoprazole, metoprolol. Parenteral Sympathetic nerve block Adult: As 1% soln: 50 mg for cervical block or 50-100 mg for lumbar block. Hepatic impairment: Dosage reduction may be needed. Incompatibility: Amphotericin B, sulfadiazine Na, methohexital Na, cefazolin Na, phenytoin Na, pantoprazole, metoprolol. Epidural Epidural anaesthesia Adult: 2-3 mL administered for each dermatome to be anaesthesised. Recommended doses are: Lumbar epidural 250-300 mg (as 1% soln) for analgesia and 225-300 mg (as 1.5% soln) or 200-300 mg (as 2% soln) for anaesth; for thoracic epidural: 200-300 mg (as 1% soln). For obstetric caudal analgesia: 200-300 mg (as 1% soln); for surgical caudal anaesth: 225-300 mg (as 1.5% soln). For continuous epidural or caudal anaesth, not to repeat max doses more frequently than 1.5 hrly. Hepatic impairment: Dosage reduction may be needed. Incompatibility: Amphotericin B, sulfadiazine Na, methohexital Na, cefazolin Na, phenytoin Na, pantoprazole, metoprolol. Intraspinal Spinal anaesthesia Adult: As hyperbaric soln of 1.5% or 5% lidocaine in 7.5% glucose soln. Normal vaginal delivery: Up to 50 mg (as 5% soln) or 9-15 mg (as 1.5% soln). Caesarian operation: Up to 75 mg (as 5% soln). Other surgical procedures: 75-100 mg. Hepatic impairment: Dosage reduction may be needed. Incompatibility: Amphotericin B, sulfadiazine Na, methohexital Na, cefazolin Na, phenytoin Na, pantoprazole, metoprolol. Intravenous As an intravenous regional anaesthesia Adult: As 0.5% soln w/o epinephrine: 50-300 mg. Max: 4 mg/kg. Hepatic impairment: Dosage reduction may be needed. Incompatibility: Amphotericin B, sulfadiazine Na, methohexital Na, cefazolin Na, phenytoin Na, pantoprazole, metoprolol. Urethral Surface anaesthesia Adult: As 2% gel: Female: 60-100 mg inserted into the urethra several min before examination. Male: 100-200 mg before catheterisation and 600 mg before sounding or cystoscopy. Intramuscular Emergency treatment of ventricular arrhythmias Adult: 300 mg injected into the deltoid muscle, repeat after 60-90 min if necessary. Hepatic impairment: Dosage reduction may be needed. Incompatibility: Amphotericin B, sulfadiazine Na, methohexital Na, cefazolin Na, phenytoin Na, pantoprazole, metoprolol. Parenteral Percutaneous infiltration anaesthesia Adult: As 0.5% or 1% soln: 5-300 mg. Hepatic impairment: Dosage reduction may be needed. Incompatibility: Amphotericin B, sulfadiazine Na, methohexital Na, cefazolin Na, phenytoin Na, pantoprazole, metoprolol. Parenteral Peripheral nerve block Adult: As 1.5% soln: For brachial plexus block: 225-300 mg. As 2% soln: For dental nerve block: 20-100 mg. As 1% soln: For intercostal nerve block: 30 mg; for paracervical block: 100 mg on each side, repeated not more frequently than every 90 min; for paravertebral block: 30-50 mg; for pudendal block: 100 mg on each side. As 4% soln: For retrobulbar block: 120-200 mg. Hepatic impairment: Dosage reduction may be needed. Incompatibility: Amphotericin B, sulfadiazine Na, methohexital Na, cefazolin Na, phenytoin Na, pantoprazole, metoprolol.
Drug Dose Lidocaine Injection will be given to you by a doctor, or nurse in hospital or a dentist. Your doctor or dentist will choose the dose that is right for you. •Lidocaine Injection is injected into the area that needs to be numbed •You will be given the lowest possible dose. •The exact dose you will be given depends on the area to be numbed, the way the injection is being given and how you respond to it. •Your doctor or nurse may put a tight band (tourniquet) around your limb if you require what is called intravenous regional anaesthesia (or Bier''s block). The band is kept in place for at least 20 minutes after injection. This keeps the lidocaine in the area it is needed.
Excess Drug Consumption Symptoms: Severe hypotension, asystole, bradycardia, apnoea, seizures, coma, cardiac arrest, resp arrest and death. Management: Maintain oxygenation, stop convulsion and support the circulation.
Forgot Drug Consumption
Stop Drug Consumption
Possible Side Effects
General Information Arrhythmia, bradycardia, arterial spasms, CV collapse, oedema, flushing, heart block, hypotension, sinus node suppression, agitation, anxiety, coma, confusion, drowsiness, hallucinations, euphoria, headache, hyperaesthesia, hypoaesthesia, lightheadedness, lethargy, nervousness, psychosis, seizure, slurred speech, unconsciousness, somnolence, nausea, vomiting, metallic taste, tinnitus, disorientation, dizziness, paraesthesia, resp depression and convulsions. Patch: Bruising, depigmentation, petechiae, irritation. Ophth: Conjunctival hyperaemia, corneal epithelial changes, diplopia, visual changes. Potentially Fatal: Hypotension and bradycardia leading to cardiac arrest.
Common Drug Side Effects Like all medicines Lidocaine Injection can cause side effects, although not everybody gets them. Seek immediate medical help if you have any of the following symptoms: Allergic reactions causing -Swelling of hands, feet, lips, mouth, tongue or throat -Difficulties breathing -Itchy skin rash -Diarrhoea and stomach pains -Collapse. The other side effects are: Effects on the lungs •breathing problems and stopping breathing Effects on the heart and circulation: •changes in heartbeat, including the heart stopping •low blood pressure •high blood pressure Effects on the nervous system •unconsciousness •fits •twitching or tremors •feeling sick or being sick •dizziness or light headedness •drowsiness •mood changes or a feeling of fear •a feeling of confusion or delusion •sensations of heat, cold or numbness •tingling, prickling, pins and needles Other effects •blurred or double vision •uncontrolled movement of the eyes •ringing in the ears •pain or discomfort in the buttocks or legs If any of the side effects gets serious, or if you notice any side effects not listed, please tell your doctor or nurse.
Rare Drug Side Effects
Very Rare Drug Side Effects
Drug Side Effects Symptoms
How to Store the Medicine
How to Store the Medicine Epidural: Store below 25°C. Intramuscular: Store below 25°C. Intraspinal: Store below 25°C. Intravenous: Store below 25°C. Parenteral: Store below 25°C

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