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  3. ATRMIN 250MG CAPSULE

ATRMIN 250MG CAPSULE, Pack of 10 CAPSULES
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Composition :

PENICILLAMINE-250MG

Manufacturer/Marketer :

Chandra Bhagat Pharma Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About ATRMIN 250MG CAPSULE

ATRMIN 250MG CAPSULE is used to treat severe rheumatoid arthritis, Wilson's disease, and cystinuria. Rheumatoid arthritis is a joint disorder in which our immune system attacks our body cells. Wilson disease is a genetic problem characterized by excess copper deposited in body parts like the eye, brain, and liver leading to metal toxicity. Cystinuria is the excess build-up of an amino acid called cystine in the urinary bladder and kidney, leading to harmful effects. 

ATRMIN 250MG CAPSULE contains Penicillamine, which works by blocking the action of certain chemical messengers responsible for inflammation and slowing the progress of the condition with certain joint diseases. It works in Wilson's disease by binding to the extra copper in the body and causing it to leave the body through the urine. Decreasing copper levels improves liver function and mental, mood, and nerve problems (like confusion and difficulty speaking or walking) caused by Wilson's disease. Besides this, ATRMIN 250MG CAPSULE is also used to treat cystinuria (kidney and bladder stone) and lead poisoning.

Take ATRMIN 250MG CAPSULE exactly as prescribed by your doctor. You are advised to take ATRMIN 250MG CAPSULE as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects such as protein in the urine, low blood platelets, stomach upset or throwing up, diarrhoea, change in taste, loss of appetite,  mouth irritation, and mouth sores. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

To treat your condition effectually, continue taking ATRMIN 250MG CAPSULE for as long as your doctor has prescribed. To avoid recurring symptoms, do not stop it midway. Do not take ATRMIN 250MG CAPSULE if you are pregnant or planning for pregnancy, as ATRMIN 250MG CAPSULE causes serious congenital disabilities. ATRMIN 250MG CAPSULE should not be taken by breastfeeding mothers as it passes into breast milk. Your doctor may advise you to undergo regular blood tests, as well as kidney and liver tests, to monitor your condition. Inform your doctor about your health condition and medicines to rule out any unpleasant side effects.

Uses of ATRMIN 250MG CAPSULE

Treatment of Rheumatoid arthritis, Wilson's disease, Cystinuria, and Lead poisoning.

Directions for Use

• ATRMIN 250MG CAPSULE should be taken 1 hour before or 2 hours after a meal. Avoid drinking milk while taking ATRMIN 250MG CAPSULE.• Your doctor will determine the dosage and timing of this medication based on your medical condition. Typically, it is taken 3-4 times daily.• Swallow ATRMIN 250MG CAPSULE as a whole with a glass of water.• Do not crush, chew, or break it.

Medicinal Benefits

ATRMIN 250MG CAPSULE contains Penicillamine, which is primarily used to treat Wilson's disease (copper builds up in the body and may result in serious symptoms), and cystinuria (kidney stones). It is also used in combination with other treatments to treat severe rheumatoid arthritis. The treatment of rheumatoid arthritis ATRMIN 250MG CAPSULE reduces pain, inflammation, and slow joint damage and disease progression over time; hence ATRMIN 250MG CAPSULE is known as a disease-modifying anti-rheumatic drug (DMARD). In Wilson's disease, ATRMIN 250MG CAPSULE works by binding to the extra copper in the body and causing it to leave the body through the urine. Decreasing copper levels improves liver function and the mental, mood, and nerve problems (such as confusion, and difficulty speaking/walking) caused by Wilson's disease. In cystinuria, it helps decrease the amount of a certain substance (cystine) by binding to that substance which can cause kidney stones and prevent it from building up and forming stones. Besides this, ATRMIN 250MG CAPSULE is also used to treat lead poisoning.

How ATRMIN 250MG CAPSULE Works

ATRMIN 250MG CAPSULE contains Penicillamine, which works by blocking the action of certain chemical messengers responsible for inflammation and slowing the progress of the condition with certain joint diseases. It works in Wilson's disease by binding to the extra copper in the body and causing it to leave the body through the urine. Decreasing copper levels improves liver function and mental, mood, and nerve problems (like confusion and difficulty speaking or walking) caused by Wilson's disease. Besides this, ATRMIN 250MG CAPSULE is also used to treat cystinuria (kidney and bladder stone) and lead poisoning.

Storage

Store in a cool and dry place away from sunlight
Side effects of Atrmin 250mg Capsule
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Regularly brush and floss your teeth.
  • Rinse your mouth with water and baking soda a solution to neutralize acid in the mouth. This makes your food taste as it should.
  • Drink plenty of water or non-caffeinated drinks to prevent dry mouth which may lead to altered taste.
  • Try ginger, peppermint, fruit or green teas, lemonade, ginger ale or fruit juice to help mask unpleasant tastes.
  • Try sucking on sugar-free ice pops or ice cubes to prevent dry mouth.
  • Increased protein levels indicate the body is dehydrated and when blood plasma is concentrated.
  • Consume water and stay hydrated. Talk to your doctor and take an oral rehydrating salt (ORS).
  • Sleep for 7-8 hours per night to assist your body in repairing and rebuilding hydration.
  • Manage your blood pressure by implementing changes in lifestyle like losing weight, reducing stress and exercising regularly.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
  • Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
  • Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
  • Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
  • Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
  • If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
  • In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
  • Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
  • If you experience severe bleeding or bruising, seek emergency medical attention immediately.
  • Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
  • Get sufficient sleep and manage stress which helps in improving white blood cell count.
  • Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
  • Try to prevent the factors that cause a decrease in the white blood cells that may lead to impaired immunity.

What if I have taken an overdose of ATRMIN 250MG CAPSULE

Avoid exceeding the recommended dose as it might cause an overdose. Seek immediate medical attention if you experience any unusual symptoms.

Drug Warnings

Do not take ATRMIN 250MG CAPSULE if you are allergic (hypersensitive) to penicillamine or any of the other ingredients in it. Inform your doctor if you have severe kidney problems, lupus erythematosus (an auto-immune disorder), agranulocytosis (a low white cell blood count), aplastic anaemia (symptoms including feeling tired, breathless, having pale skin and more susceptible to infection) or thrombocytopenia (a blood disorder which causes bleeding into your skin, bruising and bleeding more than normal). Do not take ATRMIN 250MG CAPSULE if you are pregnant or planning to get pregnant and breastfeeding. This medicine may cause harm to the unborn baby if you take it while you are pregnant. Caution should be required while taking ATRMIN 250MG CAPSULE by elderly patients as they may be at greater risk of suffering side effects if you are taking ATRMIN 250MG CAPSULE over a long time, especially if you are on a restricted diet, as this medicine increases the requirement for pyridoxine (Vitamin B6) so your doctor may also prescribe this vitamin for you. If you are taking iron tablets, antacids, or digoxin (used to treat heart failure), please maintain two hours gap between these tablets and ATRMIN 250MG CAPSULE. Low blood cell counts have happened while taking ATRMIN 250MG CAPSULE. If blood cell counts get very low, this can lead to bleeding problems, infections, or anaemia, and sometimes, these have been deadly. 

Drug-Drug Interactions

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PenicillamineSodium aurothiomalate
Severe
PenicillamineDeferiprone
Severe

Drug-Drug Interactions

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PenicillamineSodium aurothiomalate
Severe
How does the drug interact with Atrmin 250mg Capsule:
Using Atrmin 250mg Capsule together with sodium aurothiomalate can increase the severity of adverse effects of Atrmin 250mg Capsule.

How to manage the interaction:
There may be a possibility of interaction between Sodium aurothiomalate and Atrmin 250mg Capsule, but it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without talking to your doctor.
PenicillamineDeferiprone
Severe
How does the drug interact with Atrmin 250mg Capsule:
Deferiprone when taken with Atrmin 250mg Capsule can cause an increased risk of low blood levels.

How to manage the interaction:
Co-administration of Atrmin 250mg Capsule with Deferiprone can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
PenicillamineTenofovir alafenamide
Severe
How does the drug interact with Atrmin 250mg Capsule:
Taking Atrmin 250mg Capsule and tenofovir alafenamide can increase the risk of kidney problems.

How to manage the interaction:
Taking Atrmin 250mg Capsule and Tenofovir alafenamide together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
PenicillamineMetrizamide
Severe
How does the drug interact with Atrmin 250mg Capsule:
Taking Atrmin 250mg Capsule together with metrizamide can cause severe kidney problems.

How to manage the interaction:
Although taking Atrmin 250mg Capsule and Metrizamide together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
PenicillamineCladribine
Severe
How does the drug interact with Atrmin 250mg Capsule:
Taking cladribine with Atrmin 250mg Capsule can increase the risk of developing serious infections.

How to manage the interaction:
Taking Cladribine with Atrmin 250mg Capsule together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
PenicillamineClozapine
Severe
How does the drug interact with Atrmin 250mg Capsule:
Taking Atrmin 250mg Capsule with Clozapine can increase the risk of low blood levels.

How to manage the interaction:
Taking Atrmin 250mg Capsule with Clozapine together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
PenicillamineIodamide
Severe
How does the drug interact with Atrmin 250mg Capsule:
Using iodamide together with Atrmin 250mg Capsule can cause an increased risk of kidney problems.

How to manage the interaction:
Although there is a drug interaction between Atrmin 250mg Capsule and iodamide, they can be taken together if advised by the doctor. If you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm consult your doctor immediately. Do not discontinue medications without consulting a doctor.
PenicillamineIoversol
Severe
How does the drug interact with Atrmin 250mg Capsule:
Using ioversol together with Atrmin 250mg Capsule can cause an increased risk of kidney problems.

How to manage the interaction:
Although there is a drug interaction between Atrmin 250mg Capsule and ioversol, they can be taken together if advised by the doctor. If you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm consult your doctor immediately. Do not discontinue medications without consulting a doctor.
PenicillamineLeflunomide
Severe
How does the drug interact with Atrmin 250mg Capsule:
Using Atrmin 250mg Capsule with leflunomide can increase the risk of low blood levels.

How to manage the interaction:
There may be a possibility of interaction between Leflunomide and Atrmin 250mg Capsule, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
PenicillamineTenofovir disoproxil
Severe
How does the drug interact with Atrmin 250mg Capsule:
Coadministration of Tenofovir disoproxil with Atrmin 250mg Capsule can increase the risk of developing kidney problems.

How to manage the interaction:
Taking Tenofovir disoproxil with Atrmin 250mg Capsule can possibly result in an interaction, it can be taken when your doctor has advised it. However, if you experience vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, shortness of breath, muscle cramps, dizziness, and irregular heart rhythm contact your doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30 minutes of walking or swimming would be helpful.

  • Performing yoga may also help in improving joint flexibility and pain management.

  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.

  • Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.

  • Follow heat or cold therapy, apply a cold or hot compress on the joints for 15-20minutes regularly.

  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listen to soothing music.

  • Acupuncture, massage and physical therapy may also be helpful.

  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.

  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.

  • Drink plenty of fluids.

  • Limit consumption of spinach, wheat bran, nuts, beets and dairy products.

  • Avoid high salt intake and foods containing baking soda.

  • Follow work safety regulations if you are at risk of occupational exposure. Wear necessary protective gear while working and do not take any contaminated material such as clothing or work gear to home. 

  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

CHELATING AGENTS

ATRMIN 250MG CAPSULE Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking ATRMIN 250MG CAPSULE. It could lead to increased dizziness and drowsiness.

bannner image

Pregnancy

Unsafe

ATRMIN 250MG CAPSULE is a pregnancy category D drug. It is not recommended to take ATRMIN 250MG CAPSULE while you are pregnant. ATRMIN 250MG CAPSULE may cause serious birth defects.

bannner image

Breast Feeding

Unsafe

ATRMIN 250MG CAPSULE should not be used in breastfeeding mothers as ATRMIN 250MG CAPSULE passes into breast milk.

bannner image

Driving

Caution

ATRMIN 250MG CAPSULE may cause dizziness, drowsiness and tiredness; do not drive or operate heavy machinery if you feel dizzy.

bannner image

Liver

Unsafe

ATRMIN 250MG CAPSULE is not recommended for the liver patients.

bannner image

Kidney

Caution

ATRMIN 250MG CAPSULE should be used with caution in patients with kidney diseases. Dose adjustments may be necessary.

bannner image

Children

Safe if prescribed

ATRMIN 250MG CAPSULE should be used in children under the care of the doctor. The dose may depend on the weight and age of the child.

Have a query?

FAQs

ATRMIN 250MG CAPSULE is used to treat severe rheumatoid arthritis, Wilsons disease, and cystinuria. Rheumatoid arthritis is a joint disorder in which our immune system attacks our body cells. Wilson disease is a genetic problem characterized by excess copper deposited in body parts like the eye, brain, and liver, leading to metal toxicity. Cystinuria is the excess build-up of an amino acid called cystine in the urinary bladder and kidney, leading to harmful effects.

ATRMIN 250MG CAPSULE works by blocking the action of certain chemical messengers that are responsible for inflammation and prevents joint stiffness, thereby provides relief from rheumatoid arthritis.

Wilson’s disease is a condition where the body cannot get rid of copper properly and cause damage the liver, brain, and other organs. ATRMIN 250MG CAPSULE contains penicillamine that works by helping the body to remove excess copper.

Avoid taking other medicines at the same time while taking ATRMIN 250MG CAPSULE. If you take an iron supplement, take it at least 2 hours before or after you take ATRMIN 250MG CAPSULE. Iron can make it harder for your body to absorb ATRMIN 250MG CAPSULE. Avoid taking mineral supplements, unless your doctor advised you to. Do not drink milk within 1 hour before or after you take ATRMIN 250MG CAPSULE. Do not take copper-containing foods like shellfish, chocolate, nuts, mushroom, and organ meats (liver pate, sweetbreads etc.)

ATRMIN 250MG CAPSULE may cause side-effects such as protein in urine, low blood platelets, stomach upset or throwing up, diarrhea , change in taste, loss of appetite, mouth irritation, mouth sores. These side-effects are usually mild and temporary. However, if any of these side-effects persist or get worse, inform your doctor immediately.

ATRMIN 250MG CAPSULE should not be taken during pregnancy or if you are trying to become pregnant as ATRMIN 250MG CAPSULE can cause birth defects, miscarriages or harm unborn babies. Avoid becoming pregnant for at least 6 months after stopping the treatment with ATRMIN 250MG CAPSULE.

ATRMIN 250MG CAPSULE belongs to the class of medications called disease-modifying antirheumatic drugs (DMARDs). It is used to treat various conditions, including Wilson's disease, rheumatoid arthritis, and cystinuria.

No, ATRMIN 250MG CAPSULE is not an antibiotic. It is actually a disease-modifying antirheumatic drug (DMARD) used to treat conditions like Wilson's disease, rheumatoid arthritis, and cystinuria.

Country of origin

India

Manufacturer/Marketer address

501, The Bureau, R C MARG, Nr.Chembur Naka, Chembur East, Mumbai - 400071
Other Info - ATR0056

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:47 AM IST

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Reference

  1. https://www.drugs.com/cdi/penicillamine.html
  2. https://www.medicines.org.uk/emc/files/pil.4069.pdf
  3. https://www.accessdata.fda.gov/drugsatfda_docs/label/2004/19853s012,014lbl.pdf

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