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  3. Axid D 10mg/20mg Tablet

Axid D 10mg/20mg Tablet, Pack of 1 Tablet
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Composition :

DOMPERIDONE-10MG + RABEPRAZOLE-20MG

Manufacturer/Marketer :

Bajaj Pharmaceuticals

Consume Type :

ORAL

Return Policy :

Not Returnable

About Axid D 10mg/20mg Tablet

Axid D 10mg/20mg Tablet belongs to the class of drugs known as Proton pump inhibitors, which reduce the amount of acid your stomach produces. It treats gastroesophageal reflux disease (GERD), stomach ulcers, Zollinger-Ellison syndrome (overproduction of acid due to a pancreatic tumour), duodenal ulcers, gastric ulcers, and Crohn’s disease-associated ulcers.

Axid D 10mg/20mg Tablet helps reduce stomach acid by blocking the action of an enzyme (H+/K+ ATPase, also known as the gastric proton pump), thus preventing the release of stomach acid and relieving symptoms of food pipe lining inflammation (esophagitis), gastroesophageal reflux disease (GERD), or heartburn.

Not everyone who is taking Axid D 10mg/20mg Tablet will get these side effects. Axid D 10mg/20mg Tablet may have common side effects, such as headache, diarrhoea, nausea, abdominal pain, vomiting, dizziness, and joint pain. These side effects are temporary and may resolve on their own over time. However, if these side effects persist, don't hesitate to contact your doctor.

Take Axid D 10mg/20mg Tablet as advised. Your physician will decide the dosage based on your medical condition. You should take Axid D 10mg/20mg Tablet 30 minutes before food. It is recommended not to exceed the recommended dose of Axid D 10mg/20mg Tablet. Do not chew, crush, or break the medicine.

Inform your physician if you are allergic to Axid D 10mg/20mg Tablet. Tell your doctor if you have stomach or intestinal cancer, liver problems, are allergic to Axid D 10mg/20mg Tablet or will have an endoscopy in the future. Prolonged intake of Axid D 10mg/20mg Tablet may cause a deficiency of Vitamin B12 and low levels of calcium, magnesium and Vitamin D, leading to osteoporosis. Axid D 10mg/20mg Tablet is not recommended for children below 5 years of age. Consult the doctor if you are pregnant or breastfeeding.

Uses of Axid D 10mg/20mg Tablet

Axid D 10mg/20mg Tablet is used in the treatment of acid reflux symptoms caused by peptic ulcer, Zollinger-Ellison syndrome (overproduction of acid due to a pancreatic tumour) and gastro-esophagal reflux disease (GERD). The detailed uses of Axid D 10mg/20mg Tablet are as follows:<br/>• Support Digestive Health: Axid D 10mg/20mg Tablet help alleviate digestive discomfort, promoting a balanced and regular digestive system.<br/>• Reduce Gastrointestinal Disorders: Axid D 10mg/20mg Tablet provides relief from various gastrointestinal issues, such as gas, bloating, and irregular bowel movements.<br/>• Relieve Indigestion: Axid D 10mg/20mg Tablet offers quick relief from indigestion and related symptoms, soothing the stomach and enhancing overall comfort.<br/>

Directions for Use

• Take Axid D 10mg/20mg Tablet one hour before a meal or as advised by your doctor. • Follow your doctor's instructions on the dosage and timing of this medication. • Swallow Axid D 10mg/20mg Tablet as a whole with a glass of water. • Do not crush, chew or break it.

Medicinal Benefits

  • Axid D 10mg/20mg Tablet is effective in healing erosive esophagitis (inflammation of the food pipe), heartburn, Zollinger-Ellison syndrome, duodenal ulcers, gastric ulcers, and Crohn’s disease-associated ulcers.
  • Axid D 10mg/20mg Tablet works by irreversibly blocking the proton pump gate, which secretes stomach acid. It can be prescribed to all age groups, including special populations like the elderly, pregnant, lactating mothers, and patients with kidney and liver disease.
  • Axid D 10mg/20mg Tablet helps manage acidity-related conditions, promotes digestion, and provides relief from associated discomfort.

How Axid D 10mg/20mg Tablet Works

Axid D 10mg/20mg Tablet contains two medicines, namely Rabeprazole and Domperidone. Rabeprazole helps reduce stomach acid by blocking the actions of an enzyme (H+/K+ ATPase or gastric proton pump). This gastric proton pump lies in the cells of the stomach wall. It is responsible for releasing gastric acid secretion and damaging tissues in the food pipe, stomach, and duodenum (uppermost part of the small intestine). On the other hand, Domperidone increases the motility of the upper gastrointestinal tract and blocks the vomiting-inducing centre (chemoreceptor trigger zone-CTZ).

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Axid D 10mg/20mg Tablet

Do not take more than the prescribed dose of Axid D 10mg/20mg Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

  • Avoid taking Axid D 10mg/20mg Tablet if you are allergic to Axid D 10mg/20mg Tablet or have any history of gastric cancer, liver disease, low magnesium levels, or low vitamin B1.
  • Prolonged intake of Axid D 10mg/20mg Tablet may cause lupus erythematosus (an inflammatory condition in which the immune system attacks its own tissues), vitamin B12, and magnesium deficiency.
  • Axid D 10mg/20mg Tablet may interact with blood thinners, antifungals, anti-HIV drugs, iron supplements, and anti-cancer medications. Please inform your doctor if you are taking any of these medications.
  • Intake of Axid D 10mg/20mg Tablet may mask the symptoms of gastric cancer, so if you have any severe stomach pain or blood in stool, immediately consult the doctor.
  • It is advised to stop consuming alcohol and smoking, as it can cause serious side effects. This medicine is not recommended for use in children below 16 years of age.
  • Avoid caffeine-containing beverages (coffee, tea), spicy/deep-fried/processed foods, carbonated drinks, and acidic foods like citrus fruits/vegetables (tomatoes).
  • Although Axid D 10mg/20mg Tablet is safe for use during pregnancy or breastfeeding, inform your doctor if you are pregnant or breastfeeding before starting treatment with Axid D 10mg/20mg Tablet. Let your doctor know if you are taking any other medicines, including supplements and herbal products, to prevent any interactions.
  • Store Axid D 10mg/20mg Tablet at room temperature. Keep the medicine out of reach of children. Do not take more than the recommended dose of medicine, as it can cause undesirable effects.
  • It is always important to check the expiry date of the medicine. Discard the medicine if it reaches the expiry date.

Drug-Drug Interactions

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RabeprazoleErlotinib
Critical
RabeprazoleRilpivirine
Critical

Drug-Drug Interactions

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RabeprazoleErlotinib
Critical
How does the drug interact with Axid D 10mg/20mg Tablet:
When used in combination with erlotinib, Axid D 10mg/20mg Tablet may prevent the absorption of erlotinib into the circulation, which might make erlotinib less effective in treating cancer.

How to manage the interaction:
Taking Axid D 10mg/20mg Tablet with Erlotinib is not recommended as it can result in an interaction, it should be taken only if a doctor has advised it. Do not stop using any medications without consulting a doctor.
RabeprazoleRilpivirine
Critical
How does the drug interact with Axid D 10mg/20mg Tablet:
Co-administration of Axid D 10mg/20mg Tablet can make Rilpivirine less effective by reducing its absorption in the body.

How to manage the interaction:
Taking Axid D 10mg/20mg Tablet with Rilpivirine is not recommended, but can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.
DomperidoneToremifene
Severe
How does the drug interact with Axid D 10mg/20mg Tablet:
Coadministration of Axid D 10mg/20mg Tablet with Toremifene can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Axid D 10mg/20mg Tablet and Toremifene together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneNefazodone
Severe
How does the drug interact with Axid D 10mg/20mg Tablet:
Coadministration of Axid D 10mg/20mg Tablet with Nefazodone can increase the blood levels of Axid D 10mg/20mg Tablet.

How to manage the interaction:
There may be a possibility of interaction between Axid D 10mg/20mg Tablet and Nefazodone, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.
DomperidoneCisapride
Severe
How does the drug interact with Axid D 10mg/20mg Tablet:
Coadministration of Axid D 10mg/20mg Tablet with Cisapride can increase the blood levels of Axid D 10mg/20mg Tablet.

How to manage the interaction:
There may be a possibility of interaction between Axid D 10mg/20mg Tablet and Cisapride, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.
DomperidoneBepridil
Severe
How does the drug interact with Axid D 10mg/20mg Tablet:
Co-administration of Domeperidone and Bepridil can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Axid D 10mg/20mg Tablet and Bepridil together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneCitalopram
Severe
How does the drug interact with Axid D 10mg/20mg Tablet:
Coadministration of Axid D 10mg/20mg Tablet with Citalopram can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Axid D 10mg/20mg Tablet and Citalopram together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneKetoconazole
Severe
How does the drug interact with Axid D 10mg/20mg Tablet:
Coadministration of Axid D 10mg/20mg Tablet with Ketoconazole can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Axid D 10mg/20mg Tablet and Ketoconazole together can cause an interaction, it can be taken if a doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneMethadone
Severe
How does the drug interact with Axid D 10mg/20mg Tablet:
Coadministration of Axid D 10mg/20mg Tablet with Methadone can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Axid D 10mg/20mg Tablet and Methadone together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneClarithromycin
Severe
How does the drug interact with Axid D 10mg/20mg Tablet:
Coadministration of Axid D 10mg/20mg Tablet with Clarithromycin can increase the risk of side effects.

How to manage the interaction:
There may be a possibility of interaction between Axid D 10mg/20mg Tablet and Clarithromycin, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid intake of acid or heartburn-triggering foods or drinks like onions, peppermint, chocolate, caffeinated beverages, citrus fruits or juices, tomatoes and high-fat and spicy foods.
  • Avoid taking alcohol and smoking cigarette. Alcohol can raise the level of production of stomach acid leading to heartburn and acid reflux. On the other hand, nicotine smoking damages the valve (sphincter), preventing stomach acid backflow into the food pipe.
  • Avoid regular sitting continuously, as it can increase stomach acid production. Try to take a break of 5 minutes in 1 hour by brisk walking or stretching.
  • Before going to sleep, try to raise your bedhead so that your head and chest are higher than your feet. Do not use piles of pillows, instead, one raised block is fine. This will not allow the stomach acid to backflow through your food pipe.
  • Include high fibre containing foods, berries, cherries, leafy green veggies (kale, spinach) and black peppers in your meal. These foods are full of antioxidants, calcium and vitamin B 12 that can help cope with the long-term effects of the medicine.
  • Fermented dairy products like miso, sauerkraut, and kimchi contain probiotics which help in the prevention of excess stomach acid production. Cranberry juice can be beneficial in the peptic ulcer and H Pylori infection.

Habit Forming

No

Therapeutic Class

GASTROINTESTINAL AGENTS

Axid D 10mg/20mg Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Drinking alcohol with Axid D 10mg/20mg Tablet may cause dehydration and elevate the level of stomach acid, thereby decreasing its efficiency. So try to avoid, limit alcohol or contact a doctor before intake of Axid D 10mg/20mg Tablet.

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Pregnancy

Consult your doctor

It is not known whether the Axid D 10mg/20mg Tablet affects the baby or not. So, contact a doctor before intake of Axid D 10mg/20mg Tablet. Your doctor will weigh the benefits and potential risks before prescribing them.

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Breast Feeding

Consult your doctor

Domperidone present in Axid D 10mg/20mg Tablet passes into the breast milk. However, no evidence of risk has been reported. Please consult your doctor before intake of Axid D 10mg/20mg Tablet. Your doctor will weigh the benefits and potential risks before prescribing them.

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Driving

Caution

In some cases, Axid D 10mg/20mg Tablet may cause dizziness, sleepy, or blur vision. If you observe these symptoms do not drive or operate heavy machinery until you feel better.

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Liver

Consult your doctor

If u have or had history or evidence of any liver-related diseases, please consult the doctor before taking medicine.

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Kidney

Consult your doctor

If u have or had history or evidence of any kidney-related diseases, please consult the doctor before taking medicine.

bannner image

Children

Unsafe

Axid D 10mg/20mg Tablet is not recommended for use in children due to a lack of data on safety and efficacy. Please consult your doctor.

Have a query?

FAQs

Axid D 10mg/20mg Tablet is used to treat Gastro-Esophagal Reflux Disease (GERD), acid reflux, heartburn, peptic ulcer, stomach ulcers, and dyspepsia (stomach discomfort due to indigestion). It works by blocking the actions of the gastric proton pump, increasing the motility of the upper gastrointestinal tract and blocking the vomiting-inducing centre (chemoreceptor trigger zone-CTZ).

No. Axid D 10mg/20mg Tablet prevents excess production of stomach acid causing acid reflux and heartburn. If blood is coming in your stool or mucous immediately contact the doctor.

Yes, Axid D 10mg/20mg Tablet can cause dry mouth and it is due to domperidone. In case you fell excessive thirsty, please increase your fluid intake and do frequent mouth rinses.

Diarrhoea might be a side-effect of Axid D 10mg/20mg Tablet. Drink enough fluids and eat non-spicy food if you experience diarrhoea. Consult your doctor if you have severe diarrhoea or any other discomfort.

Avoid lying down immediately after meals to prevent acid reflux. Raise the head of the bed 10-20cm by putting on a pillow so that the head and chest are above the waist. This helps in preventing acid reflux.

Axid D 10mg/20mg Tablet is contraindicated in patients with a known hypersensitivity to domperidone or rabeprazole or any other inactive ingredients of Axid D 10mg/20mg Tablet. Axid D 10mg/20mg Tablet should be used with caution in patients with underlying liver or kidney disease.

Store Axid D 10mg/20mg Tablet at room temperature in a cool and dry place protected from light. Keep it out of reach of children.

Yes, Axid D 10mg/20mg Tablet is safe for most of the patients. However, in some patients it may cause common side effects such as stomach pain, diarrhea, flatulence (gas), dryness in mouth, headache, dizziness, and other uncommon and rare side effects. If these side effects persist or worsen, please consult your doctor.

It is preferable to take Axid D 10mg/20mg Tablet on an empty stomach or before the first meal of the day.

Yes, Axid D 10mg/20mg Tablet may increase the risk of developing irregular heartbeat (serious arrhythmias). Although, it is a serious side effect, it is extremely unlikely to occur. Patients aged above 60 years are at higher risk.

Country of origin

India
Other Info - AX52978

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:34 AM IST

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Reference

  1. https://www.ciplamed.com/content/rabicip-d-capsules
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