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Manufacturer/Marketer :

Hbc Life Sciences Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Aztra 5/12.5 Tablet 15's

Aztra 5/12.5 Tablet 15's is used to treat moderate to severe depression associated with moderate to severe anxiety. Depression is a mood disorder characterised by sadness, unhappiness, anger, hopelessness or loss. Anxiety is a mental health disorder characterised by feelings of anxiety, worry or fear that are strong enough to interfere with one’s daily activities. Anxiety and depression can occur at the same time.

Aztra 5/12.5 Tablet 15's is a combination of two drugs: Amitriptyline (tricyclic anti-depressant) and Chlordiazepoxide (benzodiazepine anxiolytic). Amitriptyline works by affecting certain chemical messengers in the brain that communicate between brain cells, thereby regulating mood and treating depression. Chlordiazepoxide works by increasing the action of a chemical messenger called GABA. This helps suppress the excessive and abnormal activity of the nerve cells in the brain. 

You are advised to take Aztra 5/12.5 Tablet 15's only for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects such as dizziness, drowsiness, dry mouth, constipation, blurred vision and bloating. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Consult your doctor immediately if you have suicidal thoughts, such as killing or harming yourself. Do not take Aztra 5/12.5 Tablet 15's if you are pregnant, as it may cause birth defects. Consult your doctor before taking Aztra 5/12.5 Tablet 15's if you are breastfeeding. Avoid driving or operating machinery as Aztra 5/12.5 Tablet 15's causes sleepiness and dizziness and might impair thinking and motor skills. Avoid consuming alcohol along with Aztra 5/12.5 Tablet 15's as it could lead to increased drowsiness and dizziness. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Aztra 5/12.5 Tablet 15's

Aztra 5/12.5 Tablet 15's is used in the treatment of depression associated with anxiety. The detailed uses of Aztra 5/12.5 Tablet 15's are as follows:<br/>• Managing Anxiety Disorders: Aztra 5/12.5 Tablet 15's is often prescribed to alleviate symptoms of anxiety, offering relief from excessive worry and nervousness.<br/>• Treating Depression: Aztra 5/12.5 Tablet 15's plays a role in treatment plans for depression, helping to improve mood and emotional well-being.<br/>• Sleep Aid: With its sedative properties, Aztra 5/12.5 Tablet 15's may assist in managing insomnia and other sleep-related concerns.<br/>• Neuropathic Pain Relief: Aztra 5/12.5 Tablet 15's is effective in alleviating chronic pain caused by nerve damage, improving the quality of life for affected individuals.<br/>• ADHD Management: As part of a comprehensive treatment approach, Aztra 5/12.5 Tablet 15's can help enhance focus and concentration in patients with attention deficit hyperactivity disorder.<br/>

Directions for Use

• Take Aztra 5/12.5 Tablet 15's with or without food or as advised by a doctor.• Follow your doctor's instructions on the dosage and timing of this medication, to ensure the safety.• Swallow the medicine as a whole with glass of water.• Do not crush, break, or chew it.

Medicinal Benefits

Aztra 5/12.5 Tablet 15's is a combination of two drugs: Amitriptyline and Chlordiazepoxide. Aztra 5/12.5 Tablet 15's is used to treat moderate to severe depression and anxiety. Amitriptyline is a tricyclic anti-depressant that affects certain chemical messengers (serotonin and/or norepinephrine) in the brain, which communicate between brain cells, thereby regulating mood and treating depression. Chlordiazepoxide is a benzodiazepine anxiolytic that works by increasing the action of a chemical messenger called GABA. This helps suppress the excessive and abnormal activity of the nerve cells in the brain. Aztra 5/12.5 Tablet 15's has a calming effect on various functions of the brain. Thereby, Aztra 5/12.5 Tablet 15's helps in treating anxiety and depression.

How Aztra 5/12.5 Tablet 15's Works

Aztra 5/12.5 Tablet 15's is a combination of two drugs: Amitriptyline (tricyclic anti-depressant) and Chlordiazepoxide (benzodiazepine anxiolytic). Amitriptyline works by affecting certain chemical messengers in the brain that communicate between brain cells, thereby regulating mood and treating depression. Chlordiazepoxide works by increasing the action of a chemical messenger called GABA. This helps suppress the excessive and abnormal activity of the nerve cells in the brain.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Aztra 5/12.5 Tablet 15's

Do not take more than the prescribed dose of Aztra 5/12.5 Tablet 15's as it may cause overdose. The symptoms of overdose include difficulty sleeping, disorientation, dizziness, blurred vision, confusion, faintness, or lightheadedness when getting up suddenly from a lying or sitting position, headache, loss of consciousness, fast/slow/irregular heartbeat, hallucinations, mood or other mental changes, seeing/hearing/feeling things that are not there, nightmares, seizures (fits), sweating, trouble breathing, unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness, or unusual excitement, nervousness, restlessness, or irritability. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Aztra 5/12.5 Tablet 15's if you are allergic to any of its contents, if you recently had a heart attack or heart problems, are taking monoamine oxidase inhibitors (MAOI). Do not take opioids with Aztra 5/12.5 Tablet 15's as it may result in increased sedation, depression, coma and death. Aztra 5/12.5 Tablet 15's should not be taken for longer durations as it may cause physical dependence. Inform your doctor before taking Aztra 5/12.5 Tablet 15's if you have bipolar disorder, eye problems, urination problems, seizures, thyroid problems, kidney or liver problems or if you are due to have any surgery. Consult your doctor immediately if you have suicidal thoughts, such as killing or harming yourself. Talk to your doctor before taking Aztra 5/12.5 Tablet 15's if you have a history of drug abuse, addiction or alcohol abuse as Aztra 5/12.5 Tablet 15's may cause dependence. Do not take Aztra 5/12.5 Tablet 15's if you are pregnant, as it may cause birth defects. Consult your doctor before taking Aztra 5/12.5 Tablet 15's if you are breastfeeding. Avoid driving or operating machinery as Aztra 5/12.5 Tablet 15's causes sleepiness, dizziness and might impair thinking and motor skills. Avoid consuming alcohol along with Aztra 5/12.5 Tablet 15's as it could lead to increased drowsiness and dizziness. Aztra 5/12.5 Tablet 15's should not be given to children as safety and effectiveness have not been established.

Drug-Drug Interactions

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ChlordiazepoxideSodium oxybate
Critical

Drug-Drug Interactions

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ChlordiazepoxideSodium oxybate
Critical
How does the drug interact with Aztra 5/12.5 Tablet:
Taking Aztra 5/12.5 Tablet with Sodium oxybate increases the risk of breathing difficulty or low blood pressure.

How to manage the interaction:
Taking Aztra 5/12.5 Tablet with Sodium oxybate is generally avoided as it can lead to an interaction, it can be taken if prescribed by a doctor. However, if you experience dizziness, shortness of breath, excessive sweating, or blurred vision, contact your doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Aztra 5/12.5 Tablet:
Combining Aztra 5/12.5 Tablet and Sparfloxacin may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Aztra 5/12.5 Tablet with Sparfloxacin may result in an interaction, it can be used if a doctor recommends it. If you have any heart problems or electrolyte imbalances, you may be susceptible. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor. Note: Sparfloxacin is no longer available in the market. Grepafloxacin should not be combined with any other medications.
AmitriptylineMesoridazine
Critical
How does the drug interact with Aztra 5/12.5 Tablet:
Coadministration of Aztra 5/12.5 Tablet and Mesoridazine may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Aztra 5/12.5 Tablet with Mesoridazine may result in an interaction, it can be used if a doctor recommends it. If you have any heart problems or electrolyte imbalances, you may be susceptible. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor.
AmitriptylineSaquinavir
Critical
How does the drug interact with Aztra 5/12.5 Tablet:
Combining Aztra 5/12.5 Tablet and Saquinavir may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Aztra 5/12.5 Tablet with Saquinavir may result in an interaction, it can be used if a doctor recommends it. If you have any heart problems or electrolyte imbalances, you may be susceptible. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Aztra 5/12.5 Tablet:
Taking Tranylcypromine with Aztra 5/12.5 Tablet can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although using Tranylcypromine and Aztra 5/12.5 Tablet together is not recommended as it can possibly result in an interaction, it can be taken if prescribed by a doctor. However, consult a doctor if you have symptoms such as confusion, hallucination, fits, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Aztra 5/12.5 Tablet:
Using Aztra 5/12.5 Tablet together with Rasagiline can increase the risk of serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is especially a mood stabilizer).

How to manage the interaction:
Although using Rasagiline and Aztra 5/12.5 Tablet together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools. Inform a doctor if you have recently taken Aztra 5/12.5 Tablet. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Aztra 5/12.5 Tablet:
Combining Methylene blue with Aztra 5/12.5 Tablet can increase the risk of serotonin syndrome (increased serotonin hormone).

How to manage the interaction:
Although using Methylene blue and Aztra 5/12.5 Tablet together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken Aztra 5/12.5 Tablet. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Aztra 5/12.5 Tablet:
Using Aztra 5/12.5 Tablet together with Safinamide can increase the risk of serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is especially a mood stabilizer).

How to manage the interaction:
Although using Safinamide and Aztra 5/12.5 Tablet together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken Aztra 5/12.5 Tablet. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Aztra 5/12.5 Tablet:
Coadministration of Aztra 5/12.5 Tablet and Cisapride may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Aztra 5/12.5 Tablet with Cisapride may result in an interaction, it can be used if a doctor recommends it. If you have any heart problems or electrolyte imbalances, you may be susceptible. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Aztra 5/12.5 Tablet:
Using Aztra 5/12.5 Tablet together with Procarbazine can increase the risk of serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is especially a mood stabilizer).

How to manage the interaction:
Although using Procarbazine and Aztra 5/12.5 Tablet together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken Aztra 5/12.5 Tablet. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a healthy diet and exercise regularly as it helps in improving overall health and boosts self-esteem.

  • Regularly attend therapy sessions.

  • Perform meditation and yoga. This helps in relieving stress and provides relaxation.

  • Follow a regular sleep pattern to improve the amount and quality of sleep you get.

  • Include foods rich in omega-fatty acids such as fish, nuts, fresh fruits, vegetables and olive oils.

  • Neurotransmitters are made up of amino acids. Amino acid-rich foods such as meat, dairy products and certain fruits and vegetables help in the proper maintenance of neurotransmitters.

  • Complex carbohydrates help in stimulating serotonin (a feel-good neurotransmitter). These include whole grains, legumes, spinach, broccoli, oranges and pears.

  • Exercising helps in the production of the body’s natural anti-depressants. It also helps in relieving stress, improving mood, boosting self-esteem and providing restful sleep.

  • Avoid smoking and alcohol consumption.

  • Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.

Habit Forming

Yes

Therapeutic Class

PSYCHOTHERAPEUTICS
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Aztra 5/12.5 Tablet 15's as it may cause increased sleepiness and dizziness.

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Pregnancy

Unsafe

Avoid taking Aztra 5/12.5 Tablet 15's if you are pregnant unless prescribed by a doctor as it may cause birth defects.

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Breast Feeding

Caution

Consult your doctor before taking Aztra 5/12.5 Tablet 15's; your doctor will decide whether Aztra 5/12.5 Tablet 15's can be taken by breastfeeding mothers or not.

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Driving

Unsafe

Aztra 5/12.5 Tablet 15's may cause sleepiness, dizziness and might impair thinking and motor skills. Do not drive or operate machinery if you experience these symptoms.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Aztra 5/12.5 Tablet 15's should not be given to children as safety and effectiveness have not been established.

Have a query?

FAQs

Aztra 5/12.5 Tablet 15's is used to treat moderate to severe depression associated with moderate to severe anxiety.

Aztra 5/12.5 Tablet 15's contains Amitriptyline and Chlordiazepoxide. Amitriptyline works by affecting certain chemical messengers (serotonin and/or norepinephrine) in the brain, which communicate between brain cells, thereby regulating mood and treating depression. Chlordiazepoxide works by increasing the action of a chemical messenger called GABA. This helps suppress the excessive and abnormal activity of the nerve cells in the brain.

Aztra 5/12.5 Tablet 15's may cause weight gain due to increased appetite. Eat a healthy diet and exercise regularly to maintain a healthy weight.

Do not discontinue Aztra 5/12.5 Tablet 15's without consulting your doctor, as it could cause withdrawal symptoms. To treat your condition effectually, continue taking Aztra 5/12.5 Tablet 15's for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Aztra 5/12.5 Tablet 15's.

Dry mouth could be a side-effect of Aztra 5/12.5 Tablet 15's. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.

Constipation might occur as a side-effect of Aztra 5/12.5 Tablet 15's. Drink plenty of fluids and eat fibre-rich food if you experience constipation. Consult your doctor if you experience severe constipation.

Aztra 5/12.5 Tablet 15's may cause side effects like dizziness and tiredness in some people. Consult the doctor if the condition persists or if you experience severe dizziness or tiredness.

Painkillers should be taken with Aztra 5/12.5 Tablet 15's only if advised by the doctor. However, opioid-based analgesics should not be taken with Aztra 5/12.5 Tablet 15's as it may cause drowsiness and breathing problems. Always check with the doctor before taking painkillers or other medicines along with Aztra 5/12.5 Tablet 15's.

Aztra 5/12.5 Tablet 15's may cause suicidal thoughts/behaviour; therefore, monitor the person taking Aztra 5/12.5 Tablet 15's for any changes in mood/behaviour and report to the doctor if you notice any unusual behaviour.

Eat a healthy diet and exercise regularly to manage weight gain associated with the use of Aztra 5/12.5 Tablet 15's. Talk to the doctor if the increase in weight bothers you.

Store Aztra 5/12.5 Tablet 15's at room temperature, protected from light and moisture. Keep it out of sight and reach of children.

Yes, Aztra 5/12.5 Tablet 15's may cause sleepiness. Do not drive or operate machinery unless you know how the medicine affects you.

Aztra 5/12.5 Tablet 15's may cause sexual problems like decreased sexual desire, inability to reach an orgasm and erectile dysfunction in men. Discuss with the doctor if you experience sexual problems during treatment with Aztra 5/12.5 Tablet 15's.

No, do not drink alcohol while taking Aztra 5/12.5 Tablet 15's. Consuming alcohol along with Aztra 5/12.5 Tablet 15's could lead to increased drowsiness & dizziness and very serious side effects.

Aztra 5/12.5 Tablet 15's may change the colour of urine to green or blue. It is generally harmless and resolves once the medicine is stopped. However, consult the doctor if you have any concerns regarding this.

Aztra 5/12.5 Tablet 15's may start working within a week. However, it might take around 4 weeks to notice the full benefits of Aztra 5/12.5 Tablet 15's. Continue taking Aztra 5/12.5 Tablet 15's for the prescribed duration to treat your condition effectively.

The active ingredients of Aztra 5/12.5 Tablet 15's are Amitriptyline (tricyclic anti-depressant) and Chlordiazepoxide (benzodiazepine anxiolytic). It is used to treat moderate to severe depression associated with moderate to severe anxiety.

Aztra 5/12.5 Tablet 15's can be taken with or without food as advised by the doctor. Swallow Aztra 5/12.5 Tablet 15's as a whole with a glass of water; do not chew or crush it.

Yes, Aztra 5/12.5 Tablet 15's is safe if taken in the dose and duration prescribed by the doctor. It should not be taken for longer durations as it may cause physical dependence.

Though Aztra 5/12.5 Tablet 15's may help you sleep better by improving your mood, it should not be used for sleep-related issues. Talk to the doctor if you have sleep-related problems.

Aztra 5/12.5 Tablet 15's may not be beneficial for heart health as it may cause QT prolongation (a condition that affects heart rhythm) in some people. Before starting treatment with Aztra 5/12.5 Tablet 15's discuss you’re your doctor if you have heart rhythm problems.

Side effects of Aztra 5/12.5 Tablet 15's include dizziness, drowsiness, dry mouth, constipation, blurred vision and bloating. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Country of origin

India

Manufacturer/Marketer address

Office No: B,412-419, Atria-The Business Hub, Kh Road, Sargasan Cross Roads, S.G.Highway, Gandhinagar-382421., Gujarat, India.
Other Info - AZT0067

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