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  3. Coaprovel 150 mg/12.5 mg Tablet 14's

Coaprovel 150 mg/12.5 mg Tablet 14's, Pack of 14 TabletS
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Composition :

HYDROCHLOROTHIAZIDE-12.5MG + IRBESARTAN-150MG

Manufacturer/Marketer :

Sanofi India Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Coaprovel 150 mg/12.5 mg Tablet

Coaprovel 150 mg/12.5 mg Tablet is an 'anti-hypertensives' medication primarily used for lowering high blood pressure (hypertension) by removing extra fluid (electrolytes) from the body. High blood pressure is a chronic condition in which the blood's force against the artery wall is high. As a result, it increases the risk of heart-related diseases like heart attack, heart failure, stroke, irregular heartbeat, and other complications.

Coaprovel 150 mg/12.5 mg Tablet is a combination of two medicines, namely: Irbesartan and Hydrochlorothiazide. Irbesartan is an angiotensin receptor blocker (ARB) that blocks the hormone angiotensin, thereby relaxing and widening the narrowed blood vessels. This allows the blood to flow more smoothly in the blood vessels, and the heart can pump more efficiently. On the other hand, Hydrochlorothiazide is a diuretic or water pill that works by removing extra water/fluid and certain electrolyte overload from the body. Together, Coaprovel 150 mg/12.5 mg Tablet lowers fluid overload, raised blood pressure, improves blood flow, and reduces the future risk of a heart attack and stroke.

Take Coaprovel 150 mg/12.5 mg Tablet as prescribed. Your doctor will advise you on how often you take your tablets based on your medical condition. You may experience nausea, taste change, upset stomach, diarrhoea, dizziness, headache, electrolyte imbalance, and decreased blood pressure in some cases. Most of these side effects of Coaprovel 150 mg/12.5 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Do not use potassium supplements or salt substitutes unless the doctor has told you. If you notice unexplained muscle pain, dark colour urine, tenderness, or weakness, especially if you also have a fever or unexplained tiredness, immediately contact the doctor. Try not to stop taking this medicine of your own. Let your doctor know about this, as it may cause a rise in blood pressure and increase heart disease and stroke risk. Inform your doctor if you are suffering from any kidney or liver or heart disease or are diabetic. Do not use Coaprovel 150 mg/12.5 mg Tablet if you cannot urinate, are dehydrated, have low blood pressure (hypotension), and have or have had cardiogenic shock (sudden stopping of blood flow to the heart). Please tell your doctor if you are taking any other medicines or are allergic to this medicine. Reducing table salt (sodium chloride) in your food often helps lower blood pressure. Do not take Coaprovel 150 mg/12.5 mg Tablet if you are more than 3 months pregnant, if you have diabetes or impaired kidney function; if you suffer from potassium deficiency (hypokalaemia)/sodium deficiency (hyponatraemia), gout (Pain and inflammation occur when a high amount of uric acid crystallises and deposits in the joints). Check your serum electrolytes, creatinine and urea, serum lipids (cholesterol and triglycerides), uric acid, and blood sugar levels regularly as advised by your doctor.

Uses of Coaprovel 150 mg/12.5 mg Tablet

Treatment of Hypertension (high blood pressure)

Directions for Use

• Coaprovel 150 mg/12.5 mg Tablet can be taken with or without food as advised by your doctor.• Follow your doctor's instructions on the dosage and timing of this medication.• Swallow Coaprovel 150 mg/12.5 mg Tablet as a whole with a glass of water.• Do not crush, break, or chew it.

Medicinal Benefits

Coaprovel 150 mg/12.5 mg Tablet is primarily used to reduce high blood pressure. It is a combination of two medicines, namely: Irbesartan and Hydrochlorothiazide. Irbesartan is an angiotensin receptor blocker (ARB) that blocks the hormone angiotensin, thereby relaxing and widening the narrowed blood vessels. This allows the blood to flow more smoothly in the blood vessels, and the heart can pump more efficiently. On the other hand, Hydrochlorothiazide is a diuretic or water pill that works by removing extra water/fluid and certain electrolyte overload from the body. Together, Coaprovel 150 mg/12.5 mg Tablet lowers fluid overload, raised blood pressure, improves blood flow, and reduces the future risk of a heart attack and stroke.

How Coaprovel 150 mg/12.5 mg Tablet Works

Coaprovel 150 mg/12.5 mg Tablet is a combination of two medicines, namely: Irbesartan and Hydrochlorothiazide. Irbesartan is an angiotensin receptor blocker (ARB) that blocks the hormone angiotensin, thereby relaxing and widening the narrowed blood vessels. This allows the blood to flow more smoothly in the blood vessels, and the heart can pump more efficiently. On the other hand, Hydrochlorothiazide is a diuretic or water pill that works by removing extra water/fluid and certain electrolyte overload from the body. Together, Coaprovel 150 mg/12.5 mg Tablet lowers fluid overload, raised blood pressure, improves blood flow, and reduces the future risk of a heart attack and stroke.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Coaprovel 150 mg/12.5 mg Tablet

Take Coaprovel 150 mg/12.5 mg Tablet only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include light-headedness, fast/slow heartbeat, and fainting. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Inform your doctor before taking Coaprovel 150 mg/12.5 mg Tablet , if you are already taking medicine that has aliskiren in it if you have diabetes or kidney problems, if you have severe liver disease, if you suffer from gout, potassium deficiency (hypokalaemia)/sodium deficiency (hyponatremia). Stop taking Coaprovel 150 mg/12.5 mg Tablet if you experience pronounced gastrointestinal troubles, blood count changes, disorders of the central nervous system, or allergic reactions.  Inform your doctor before taking Coaprovel 150 mg/12.5 mg Tablet about all your ongoing medications. Your doctor may check your blood pressure, kidney function, and the number of electrolytes in the blood at regular intervals. Coaprovel 150 mg/12.5 mg Tablet should not be given to children and adolescents under 18 years of age. Drink sufficient quantities of liquid while on this medication. If you are pregnant or breastfeeding, do not take Coaprovel 150 mg/12.5 mg Tablet as it is a category D pregnancy drug and can harm the baby.

Diet & Lifestyle Advise

  • Keep your weight under control with a BMI of 19.5-24.9.
  • Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week. Doing this can help you to lower your raised blood pressure by about 5 mm of Hg.
  • Limit intake of sodium chloride (table salt) in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.
  • If you are taking alcohol, then only one serving for women and two servings for men is advisable.
  • Quitting smoking is the best strategy to lower the risk of heart disease.
  • Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spent time with your loved ones to cope with stress and practice mindfulness techniques.
  • Monitor your blood pressure daily and if there is too much fluctuation, then immediately contact your doctor.
  • Try to include heart-healthy omega-3 fatty acids containing food and drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil to lower your elevated blood pressure.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Coaprovel 150 mg/12.5 mg Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

You are recommended not to consume alcohol and Coaprovel 150 mg/12.5 mg Tablet to avoid unpleasant side effects like drowsiness, dizziness, and liver damage.

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Pregnancy

Unsafe

Coaprovel 150 mg/12.5 mg Tablet is not recommended during pregnancy as it is a category D pregnancy drug. This medicine may cause fetal damage and can affect the unborn baby (fetus).

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Breast Feeding

Caution

Coaprovel 150 mg/12.5 mg Tablet is known to pass breast milk, but its effect on the baby is not known. So, before breastfeeding, let your doctor know about this.

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Driving

Caution

Drive with caution, Coaprovel 150 mg/12.5 mg Tablet usually causes drowsiness and affects driving ability.

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Liver

Caution

Coaprovel 150 mg/12.5 mg Tablet to be taken with caution, especially if you have had a history of liver disease. Your doctor will have to change the dosage depending on your medical condition and your reaction to treatment.

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Kidney

Caution

Coaprovel 150 mg/12.5 mg Tablet to be taken with caution, especially if you have had a history of kidney disease. Your doctor will have to change the dosage depending on your medical condition and your reaction to treatment.

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Children

Unsafe

Efficacy and safety of Coaprovel 150 mg/12.5 mg Tablet have not been established in children. So, Coaprovel 150 mg/12.5 mg Tablet should not be given to children under 18 years of age.

Have a query?

FAQs

Coaprovel 150 mg/12.5 mg Tablet is used to treat high blood pressure (hypertension).

Coaprovel 150 mg/12.5 mg Tablet is a combination of two medicines, namely: Irbesartan and Hydrochlorothiazide. Irbesartan is an angiotensin receptor blocker (ARB) that blocks the hormone angiotensin and relaxes blood vessels. This allows the blood to flow more smoothly in the blood vessels, and the heart can pump more efficiently. Hydrochlorothiazide (diuretic or water pill), removes extra water and certain electrolytes from the body. Together, both lower fluid overload, blood pressure, improves blood flow, and reduce the future risk of a heart attack.

Yes, Coaprovel 150 mg/12.5 mg Tablet can cause dizziness. It is advised to avoid driving or operate any heavy machinery while taking Coaprovel 150 mg/12.5 mg Tablet . In case you feel dizzy or lightheaded, it is advised to rest for some time until you feel better.

It's unlikely that Coaprovel 150 mg/12.5 mg Tablet affects fertility in men or women. However, in some cases, some water pills like hydrochlorothiazide may lead to erectile dysfunction. For the best advice, please consult your doctor.

In case you have missed a dose of Coaprovel 150 mg/12.5 mg Tablet , you are advised to take it as soon as you remember. However, try not to miss a dose in the first place, if it's time for you to take your next dose, then do not take both the doses together. Take only one dose; taking a double dose of Coaprovel 150 mg/12.5 mg Tablet will lead to low blood pressure.

Coaprovel 150 mg/12.5 mg Tablet can be safely taken as long as your doctor has prescribed it to you. Conditions such as high blood pressure are life-long conditions, and one should not abruptly discontinue it without discussing it with a doctor. Discontinuing Coaprovel 150 mg/12.5 mg Tablet may lead to increased blood pressure with a high risk of heart attack and stroke in the future.

No, you are advised to inform your doctor and monitor your blood pressure for at least two weeks before stopping the medicine. Depending upon your current blood pressure readings, there is a possibility your doctor may lower your medicine dosage and not recommend discontinuing it.

Please inform your doctor before surgery if you are taking Coaprovel 150 mg/12.5 mg Tablet . It needs to be stopped because it might lower the blood pressure further if taken along with certain local anaesthetic medication.

Country of origin

India

Manufacturer/Marketer address

CT Survey No.117-B, L&T Business Park, Saki Vihar Road, Powai, Mumbai 400072.
Other Info - COA0001

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 18, 2025 | 6:49 AM IST

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Reference

  1. https://www.drugs.com/hydrochlorothiazide.html
  2. https://www.medicines.org.uk/emc/files/pil.4257.pdf

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