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  3. FEZA CAPSULE

FEZA CAPSULE, Pack of 10 CAPSULES
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Composition :

CLOFAZIMINE-50MG

Manufacturer/Marketer :

Samarth Life Sciences Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About FEZA CAPSULE

FEZA CAPSULE is used to treat Leprosy (infectious disease-causing skin lesions and nerve damage). Leprosy, commonly known as Hansen's disease, is caused by Mycobacterium leprae, which is a chronic infectious disease. The illness mostly affects the skin, peripheral nerves, mucosal surfaces of the upper respiratory system, and the eyes. Leprosy can affect anyone at any age, from infancy to old age.

Clofazimine is the active component in FEZA CAPSULE. It works by inhibiting the growth of disease-causing organisms (Mycobacterium) in the body. Thus, FEZA CAPSULE aids in the treatment of Leprosy.

Take FEZA CAPSULE daily at the same time to ensure better efficacy. The dose and duration of FEZA CAPSULE can vary depending on your condition and the severity of the infection. In some situations, you may experience symptoms such as stomach and epigastric pain, diarrhoea, nausea, and vomiting. These negative impacts do not necessitate medical treatment and will gradually subside. However, if you are experiencing these undesirable effects frequently, you should consult your doctor.

Continue using FEZA CAPSULE for as long as your doctor has prescribed it to treat your illness effectively. Please inform your doctor if you have ever had an allergic response to this drug before beginning treatment with FEZA CAPSULE. FEZA CAPSULE may cause dizziness, drowsiness, or reduced alertness. Therefore, drive or operate machinery only if you are alert after taking FEZA CAPSULE. If pregnant or breastfeeding, consult your doctor before using FEZA CAPSULE. Do not use FEZA CAPSULE in more than specified doses or for an extended time. Before taking FEZA CAPSULE, inform your doctor about your medical history and any other medications you currently use to rule out possible side effects.

Uses of FEZA CAPSULE

Treatment of Leprosy

Directions for Use

• FEZA CAPSULE should be taken with food or milk to enhance its absorption and reduce gastrointestinal side effects.• It is recommended to take FEZA CAPSULE once daily or as advised by your doctor.• Chew the tablet completely before swallowing. • Do not swallow it as a whole.

Medicinal Benefits

FEZA CAPSULE contains Clofazimine, an antileprotic drug used in treating Leprosy in conjunction with other medications. It works by preventing the growth of disease-causing pathogens in the body. Thus, it aids in the treatment of Leprosy. The doctor may prescribe FEZA CAPSULE to treat various bacterial infections due to Mycobacterium.

How FEZA CAPSULE Works

Clofazimine is the active component in FEZA CAPSULE. It works by inhibiting the growth of disease-causing organisms (Mycobacterium) in the body. Thus, FEZA CAPSULE aids in the treatment of Leprosy.

Storage

Store in a cool and dry place away from sunlight
Side effects of Feza Capsule
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Avoid triggering foods like spicy and fatty foods.
  • Eat smaller meals and digestible foods.
  • Regular exercise can improve gastrointestinal health.
  • Avoid sleeping immediately after eating as it can worsen digestion and lead to discomfort.
  • Drink plenty of water to stay hydrated.
  • Manage stress through relaxation techniques.
  • Moisturize often with creams or lotions.
  • Take long, warm baths to soften scales.
  • Gently scrub dry skin with a soft sponge to exfoliate your skin.
  • Apply petroleum jelly to deep cracks.
  • Avoid itching, apply cool compresses, use gentle soaps and watch for redness and swelling.
  • See a doctor for management if your condition persists.

What if I have taken an overdose of FEZA CAPSULE

Take FEZA CAPSULE only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Please inform your doctor if you have ever had an allergic response to this drug before beginning treatment with FEZA CAPSULE. FEZA CAPSULE may cause dizziness, drowsiness, or reduced alertness. Therefore, drive or operate machinery only if you are alert after taking FEZA CAPSULE. If pregnant or breastfeeding, consult your doctor before using FEZA CAPSULE. Do not use FEZA CAPSULE in more than specified doses or for an extended time. Before taking FEZA CAPSULE, inform your doctor about your medical history and any other medications you currently use to rule out possible side effects. Sun lamps should be avoided. Clofazimine may increase your skin's sensitivity to sunlight or sunlamps. Therefore, wear protective clothing when exposed to direct sunlight and apply sunscreen with an SPF of at least 15.

Drug-Drug Interactions

verifiedApollotooltip
ClofazimineDronedarone
Critical
ClofazimineThioridazine
Critical

Drug-Drug Interactions

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ClofazimineDronedarone
Critical
How does the drug interact with Feza Capsule:
When Feza Capsule is taken with Dronedarone, can increase the risk of an irregular heart rhythm that may be serious. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
Using Feza Capsule with Dronedarone is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, call a doctor right away. Do not stop using any medications without a doctor's advice.
ClofazimineThioridazine
Critical
How does the drug interact with Feza Capsule:
When Feza Capsule is taken with Thioridazine, can increase the risk of an irregular heart rhythm that may be serious. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
Using Feza Capsule with Thioridazine is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, call a doctor right away. Do not stop using any medications without a doctor's advice.
ClofazimineDofetilide
Critical
How does the drug interact with Feza Capsule:
When Feza Capsule is taken with Dofetilide, can increase the risk of an irregular heart rhythm that may be serious. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
Using Feza Capsule with Dofetilide is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, call a doctor right away. Do not stop using any medications without a doctor's advice.
ClofazimineMesoridazine
Critical
How does the drug interact with Feza Capsule:
When Feza Capsule is taken with Mesoridazine, it can increase the risk of an irregular heart rhythm that may be serious. If you suffer from any cardiac conditions or electrolyte disturbances, you may be at higher risk.

How to manage the interaction:
Using Feza Capsule with Mesoridazine is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, call a doctor right away. Do not stop using any medications without a doctor's advice.
ClofazimineCisapride
Critical
How does the drug interact with Feza Capsule:
When Feza Capsule is taken with Cisapride, can increase the risk of an irregular heart rhythm that may be serious. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
Using Feza Capsule with Cisapride is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, call a doctor right away. Do not stop using any medications without a doctor's advice.
ClofazimineZiprasidone
Critical
How does the drug interact with Feza Capsule:
Taking Feza Capsule with Ziprasidone can increase the risk of irregular heart rhythm. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
Using Feza Capsule with Ziprasidone is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, call a doctor right away. Do not stop using any medications without a doctor's advice.
ClofazimineDisopyramide
Severe
How does the drug interact with Feza Capsule:
Co-administration of disopyramide with Feza Capsule can increase the risk of irregular heart rhythm. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
Taking disopyramide with Feza Capsule together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without consulting a doctor.
ClofazimineSotalol
Severe
How does the drug interact with Feza Capsule:
Co-administration of sotalol with Feza Capsule can increase the risk of irregular heart rhythm. If you suffer from any cardiac conditions or electrolyte disturbances, you may be at higher risk.

How to manage the interaction:
Taking sotalol with Feza Capsule together can possibly result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without consulting a doctor.
ClofazimineEfavirenz
Severe
How does the drug interact with Feza Capsule:
Co-administration of efavirenz with Feza Capsule can increase the risk of irregular heart rhythm. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
Taking efavirenz with Feza Capsule together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without consulting a doctor.
ClofazimineMethadone
Severe
How does the drug interact with Feza Capsule:
Co-administration of methadone with Feza Capsule can increase the risk of irregular heart rhythm. If you suffer from any cardiac conditions or electrolyte disturbances, you may be at higher risk.

How to manage the interaction:
Taking methadone with Feza Capsule together can possibly result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat foods rich in quercetin (a flavonoid), such as apples, cherries, broccoli, spinach and blueberries.

  • Consuming food rich in probiotics helps develop the immune system against allergies.

  • Limit intake of food that might trigger allergies, such as dairy products, soy, eggs and nuts.

  • Avoid consuming foods with excess sugar, as it may flare up inflammation.

  • Include fruits, vegetables, whole grains, healthy fats and fish in your diet.

  • Reducing stress and maintaining a good sleep cycle would be helpful.

  • Avoid getting in contact with harsh soaps, detergents and rough fabrics.

Habit Forming

No

Therapeutic Class

ANTILEPROTICS

FEZA CAPSULE Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

It is not known whether FEZA CAPSULE interacts with alcohol. Please consult your doctor.

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Pregnancy

Caution

Consult your doctor; there has been no significant research on the use of FEZA CAPSULE in pregnant women.

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Breast Feeding

Caution

Consult your doctor; there has been no significant research on the use of FEZA CAPSULE in breastfeeding/nursing moms.

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Driving

Caution

FEZA CAPSULE can occasionally cause dizziness/drowsiness. Therefore, drive only if you are alert after taking FEZA CAPSULE.

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Liver

Caution

Rarely, FEZA CAPSULE may cause liver damage. Caution should be exercised while using FEZA CAPSULE in patients with severe liver impairment.

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Kidney

Caution

Please consult your doctor if you have any concerns regarding using FEZA CAPSULE in patients with kidney impairment. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Caution

FEZA CAPSULE should be used with caution in children, only when prescribed by a child specialist.

Have a query?

FAQs

FEZA CAPSULE is used to treat Leprosy (infectious disease-causing skin lesions and nerve damage).

FEZA CAPSULE works by preventing the growth of disease-causing pathogens in the body. Thus, it aids in the treatment of Leprosy.

To treat your illness effectively, continue taking FEZA CAPSULE for as long as your doctor has prescribed it. Talk to the doctor if you have any concerns.

The common side effects of FEZA CAPSULE include stomach and epigastric pain, diarrhoea, nausea, and vomiting. If you are experiencing these side effects frequently, please consult your doctor.

FEZA CAPSULE may cause skin discoloration within a few weeks of use, ranging from orange-pink to brownish-black. This discoloration is generally reversible after stopping the medication, but it may take several months or even years for the skin to return to its normal appearance. If the skin discoloration significantly affects your mood or causes distress, please consult your doctor immediately.

FEZA CAPSULE should not be used by individuals who are allergic to any of its ingredients. It should also be avoided by patients with severe liver or kidney dysfunction, as it may worsen these conditions.

FEZA CAPSULE is generally safe when used at the dose and for the duration prescribed by your doctor. However, if you experience any unusual symptoms after taking FEZA CAPSULE, please report them to your doctor.

If you forget to take a dose of FEZA CAPSULE, take it as soon as you remember unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular schedule. Do not double the dose to make up for the missed one.

Country of origin

India

Manufacturer/Marketer address

Samarth House, 168, Bangur Nagar, Off Link Road, Near Ayappa Temple & Kallol Kali Temple, Goregaon (W), Mumbai - 400 090.
Other Info - FEZ0002

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Veda MaddalaDoctor badge

Reviewed By

Veda Maddala

M Pharmacy

Last Updated

Jul 18, 2025 | 6:53 AM IST

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Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2003/19500slr010_lamprene_lbl.pdf
  2. https://www.sciencedirect.com/topics/neuroscience/clofazimine
  3. https://www.ncbi.nlm.nih.gov/books/NBK501304/
  4. https://www.drugs.com/drug-interactions/clofazimine.html

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