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  3. Flupitrend-P Tablet 10's

Flupitrend-P Tablet 10's, Pack of 10
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Composition :

FLUPIRTINE-100MG + PARACETAMOL-325MG

Manufacturer/Marketer :

Eron Life Sciences Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Flupitrend-P Tablet

Flupitrend-P Tablet is a combination medication that belongs to the analgesic medication class. It is widely used in the treatment of acute and chronic pain, fever, headache, joint pains, dysmenorrhea (period pain), postoperative pain, toothache after dental extraction, and myalgia (muscle pain). Pain is a widely used term used to describe an unpleasant feeling or discomfort. It ranges from mild to severe. The severity of the pain depends on the underlying condition. Inflammation is the immune system's natural response to injury or infection.

Flupitrend-P Tablet contains flupirtine and paracetamol. Flupirtine is an analgesic (non-opioid analgesic) which works by blocking the transmission of pain signals to the brain to lower pain perception. Paracetamol is an analgesic (pain reliever) and an antipyretic (fever reducer), which works by blocking the release of certain chemical messengers that cause fever and pain. Thus Flupitrend-P Tablet alleviates pain and other associate conditions.

Use Flupitrend-P Tablet as directed by the physician only. The dose and duration of the medication depend on your condition and its severity. The common side effects of Flupitrend-P Tablet include nausea, vomiting, wind, abdominal discomfort, diarrhoea, constipation, heartburn, drowsiness, dizziness, headache, and depression. Most of these side effects of Flupitrend-P Tablet are temporary, do not require medical attention, and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Before taking Flupitrend-P Tablet , inform your doctor if you are allergic to flupirtine, paracetamol, or other ingredients. Besides, inform your doctor if you are pregnant, breastfeeding, or have any pre-existing conditions such as liver diseases such as hepatic encephalopathy (loss of brain function due to liver damage), chronic alcoholism, or cholestasis (reduced bile flow), renal impairment, myasthenia gravis (chronic neuromuscular disease), or heart diseases. If Flupitrend-P Tablet is given in patients with liver diseases, liver function should be monitored closely. Flupitrend-P Tablet causes drowsiness and dizziness, so drive only if you are alert. Flupitrend-P Tablet is not recommended for children younger than six years old.

Uses of Flupitrend-P Tablet

Flupitrend-P Tablet is used in the treatment of Pain relief. The detailed uses of Flupitrend-P Tablet are as follows:<br/>• Pain Relief: Flupitrend-P Tablet is a painkiller that effectively treats various types of pain, including muscle pain, joint pain, toothache, headache, post-surgery pain, and nerve pain, by blocking chemical messengers that cause pain and inflammation.<br/>• Fever Reduction: Flupitrend-P Tablet effectively reduces high fever, providing relief from discomfort and associated pain.<br/>

Directions for Use

• Flupitrend-P Tablet can be taken with or without food as advised by your doctor.• Follow your doctor's instructions on the dosage and timing of this medication.• Swallow Flupitrend-P Tablet as a whole with a glass of water.• Do not crush, break, or chew it.

Medicinal Benefits

Flupitrend-P Tablet contains flupirtine (non-opioid analgesic) and paracetamol (analgesic and antipyretic). Flupirtine works by blocking the glutamate receptors that are involved in producing pain signals. It also has muscle relaxant properties. Paracetamol acts as an analgesic and antipyretic by inhibiting the release of prostaglandins (chemical mediators) that cause pain, inflammation, and fever. Altogether provide relief from pain and associated symptoms.

How Flupitrend-P Tablet Works

Flupitrend-P Tablet contains flupirtine and paracetamol. Flupirtine is an analgesic (non-opioid analgesic) which works by blocking the transmission of pain signals to the brain to lower pain perception. Paracetamol is an analgesic (pain reliever) and an antipyretic (fever reducer), which works by blocking the release of certain chemical messengers that cause fever and pain. Thus Flupitrend-P Tablet alleviates pain and other associate conditions.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Flupitrend-P Tablet

Do not take more than the prescribed dose of Flupitrend-P Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Avoid using Flupitrend-P Tablet if you are allergic to analgesics or painkillers. People with liver diseases, kidney diseases, and elderly people above 65 years of age may require dose adjustments. If Flupitrend-P Tablet is given to patients with liver impairment, liver function should be closely monitored. It is advised to discontinue use if you notice any signs of liver damage such as nausea, vomiting, yellowed skin and eyes (jaundice), abdominal pain, loss of appetite, itchy skin, and dark-coloured urine, etc.

Drug-Drug Interactions

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ParacetamolOxazepam
Severe
ParacetamolMipomersen
Severe

Drug-Drug Interactions

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ParacetamolOxazepam
Severe
How does the drug interact with Flupitrend-P Tablet:
Co-administration of Flupitrend-P Tablet may decrease the excretion rate of Oxazepam which could result in a higher serum level.

How to manage the interaction:
Although there is a possible interaction between Oxazepam and Flupitrend-P Tablet, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
ParacetamolMipomersen
Severe
How does the drug interact with Flupitrend-P Tablet:
Co-administration of Mipomersen with Flupitrend-P Tablet may increase the risk or severity of liver injury.

How to manage the interaction:
There may be a possibility of interaction between Flupitrend-P Tablet and Mipomersen, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
ParacetamolKetamine
Severe
How does the drug interact with Flupitrend-P Tablet:
Co-administration of ketamine and Flupitrend-P Tablet may decrease the effectiveness of Ketamine which could result in a higher blood level.

How to manage the interaction:
Although taking Ketamine and Flupitrend-P Tablet together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you're feeling very sleepy or having trouble breathing, it's important to contact your doctor right away. Do not stop using any medications without a doctor's advice.
ParacetamolTeriflunomide
Severe
How does the drug interact with Flupitrend-P Tablet:
Co-administration of Teriflunomide with Flupitrend-P Tablet may increase the risk or severity of Liver problems.

How to manage the interaction:
Taking Flupitrend-P Tablet with Teriflunomide together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
ParacetamolLeflunomide
Severe
How does the drug interact with Flupitrend-P Tablet:
Co-administration of Flupitrend-P Tablet and Leflunomide may increase the risk of liver problems.

How to manage the interaction:
Although there is a possible interaction between Flupitrend-P Tablet and Leflunomide, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ParacetamolLomitapide
Severe
How does the drug interact with Flupitrend-P Tablet:
Co-administration of Lomitapide and Flupitrend-P Tablet may increase the risk of severity of liver injury.

How to manage the interaction:
Although there is a possible interaction between Flupitrend-P Tablet and Lomitapide, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
ParacetamolKetoconazole
Severe
How does the drug interact with Flupitrend-P Tablet:
Co-administration of Flupitrend-P Tablet and Ketoconazole may increase the risk of liver injury.

How to manage the interaction:
Although there is a possible interaction between Flupitrend-P Tablet and Ketoconazole, you can take these medicines together if prescribed by a doctor. However, if you have joint pain or swelling, fever, chills, unusual bleeding or bruising, skin rash, itching, over-tiredness, nausea, vomiting, loss of appetite, stomach pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact a doctor immediately as these may be signs and symptoms of liver damage. Do not discontinue the medication without consulting a doctor.
ParacetamolValdecoxib
Severe
How does the drug interact with Flupitrend-P Tablet:
Co-administration of Flupitrend-P Tablet and Valdecoxib may increase the risk or severity of adverse effects.

How to manage the interaction:
Although there is a possible interaction between Flupitrend-P Tablet and Valdecoxib, you can take these medicines together if prescribed by a doctor. However, if the side effects worsen, please consult a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Do not take alcohol.
  • Include more glucosamine, chondroitin sulphate, vitamin D, and calcium-enriched supplements. Besides this, turmeric and fish oils can help reduce inflammation in the tissue.
  • Please do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do stretching, low impact aerobic exercises like walking on a treadmill, bike riding and swimming. You can also strengthen your muscles by lifting light weights.
  • In the chronic condition of arthritis or joint pain, try to include fish like salmon, trout, tuna, and sardines. These fishes are enriched with omega-3 fatty acids that minimum level of chemical called cytokines, which ramp up inflammation.
  • Your sitting posture is important, especially when you have pain and inflammation. Try to sit as little as possible and only for a short time. Long-term immobility is harmful in conditions like arthritis. Use back support like a rolled-up towel to minimise pain at the back of your spine curve. Keep your knees and hips at a right angle. Besides this, you can also use a footrest if required.

Habit Forming

No

Therapeutic Class

ANALGESIC AND ANTIPYRETIC AGENT

Flupitrend-P Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Consuming alcohol with Flupitrend-P Tablet is not advisable as it may cause unpleasant side effects, or you may become more sensitive to the effects of alcohol.

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Pregnancy

Caution

Flupitrend-P Tablet is not recommended during pregnancy. However, your doctor may prescribe it for you during pregnancy if he/she feels the benefit outweighs the risk.

bannner image

Breast Feeding

Unsafe

According to the studies available to date, a small percentage of flupirtine maleate passes into breast milk. Therefore, flupirtine maleate must not be administered during lactation unless necessary.

bannner image

Driving

Unsafe

Avoid driving or operating heavy machinery after taking Flupitrend-P Tablet , as it may cause dizziness.

bannner image

Liver

Unsafe

Flupitrend-P Tablet can cause liver toxicity. So, it should be avoided in patients with liver diseases. However, dose adjustments and close monitoring are necessary if it is used in patients with liver diseases.

bannner image

Kidney

Caution

In patients with kidney problems, dose adjustments of Flupitrend-P Tablet are required. Therefore, use Flupitrend-P Tablet only when prescribed by a doctor.

bannner image

Children

Caution

It is recommended to consult a doctor before using Flupitrend-P Tablet in children below six years.

Have a query?

FAQs

Flupitrend-P Tablet is widely used in the treatment of acute and chronic pain, fever, headache, joint pains, dysmenorrhea (period pain), postoperative pain, toothache after dental extraction, and myalgia (muscle pain).

Flupitrend-P Tablet contains flupirtine (non-opioid analgesic) and paracetamol (analgesic and antipyretic). Flupirtine works by blocking the glutamate receptors that are involved in producing pain signals. Paracetamol acts as an analgesic and antipyretic by inhibiting the release of prostaglandins (chemical mediators) that cause pain, inflammation, and fever. Altogether provide relief from pain.

No, Flupitrend-P Tablet provides pain relief from menstrual pain (dysmenorrheal). It may not affect on periods. Please consult the doctor if you have any concerns regarding this.

Yes, Flupitrend-P Tablet can be used to treat pain associated with osteoarthritis. But, you should take it as advised by your doctor.

Flupitrend-P Tablet contains Paracetamol, known to cause liver damage when you take large dosages. Often, stop consuming alcohol when taking this drug, as this can further increase the risk of liver damage. The use of this drug in patients with underlying liver disease should preferably be avoided.

Usually, Flupitrend-P Tablet is used for a short period of time and can be stopped when the pain is relieved. It should be continued, however, if you are instructed to do so by your doctor.

The common side effects of Flupitrend-P Tablet include nausea, vomiting, wind, abdominal discomfort, diarrhoea, constipation, heartburn, drowsiness, dizziness, headache, and depression. Most of these side effects of Flupitrend-P Tablet are temporary, do not require medical attention, and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

No, do not take a higher than the recommended dose of Flupitrend-P Tablet as it may lead to unpleasant side effects/overdose. Take it as per the dose advised by the doctor.

Store Flupitrend-P Tablet at room temperature, in a dry place. Keep it out of sight and reach of children.

Country of origin

India

Manufacturer/Marketer address

C010, Arun Patios Apartment, Kenchenahalli, Yelahanka Bangalore Bangalore Ka 560064
Other Info - FLU1026

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 18, 2025 | 6:36 AM IST

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Reference

  1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3339720/
  2. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3557425/#:~:text=Adverse%20events%20commonly%20reported%20were,%2C%20depression%2C%20disorientation%20and%20hallucinations.
  3. https://www.medicines.org.uk/emc/files/pil.5916.pdfhttp://mri.cts-mrp.eu/download/DE_H_3430_001_FinalSPC_2of2.pdf
  4. https://www.ema.europa.eu/en/news/restrictions-use-flupirtine-containing-medicines-cmdh-endorses-prac-recommendation#:~:text=Flupirtine%20is%20a%20non%2Dopioid,following%20orthopaedic%20surgery%20or%20injuries.

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