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  3. Neosporin-H Ointment 5 gm

Neosporin-H Ointment 5 gm, Pack of 1
Neosporin-H Ointment 5 gm, Pack of 1
Neosporin-H Ointment 5 gm, Pack of 1
Neosporin-H Ointment 5 gm, Pack of 1
Neosporin-H Ointment 5 gm, Pack of 1
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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Neosporin-H Ointment 5 gm is used to treat bacterial eye infections. It works by killing the infection-causing bacteria and blocking the production of chemical messengers that make the affected area red, swollen and itchy. In some cases, this medicine may cause side effects such as dryness. Avoid touching the container's tip to the eye, eyelids, or surrounding areas as it may contaminate the product.

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Composition :

BACITRACIN-400UNITS + HYDROCORTISONE-10MG + NEOMYCIN-3400UNITS + POLYMYXIN B-5000UNITS

Manufacturer/Marketer :

GlaxoSmithKline Pharmaceuticals Ltd

Consume Type :

OPHTHALMIC

Return Policy :

Not Returnable

Expires on or after :

About Neosporin-H Ointment 5 gm

Neosporin-H Ointment 5 gm belongs to the class of 'antibiotics' and is primarily used to treat bacterial infections of the external eye and uveitis (inflammation of the middle layer of the eye (uvea)). Bacterial infection occurs when harmful bacteria grow in the body and cause illness. Neosporin-H Ointment 5 gm will not work for infections caused by fungi and viruses.

Neosporin-H Ointment 5 gm is composed of four medicines: Bacitracin, Hydrocortisone, Neomycin, and Polymyxin B. Bacitracin is a bacteriostatic medicine (stops the growth or reproduction of bacteria). It works by inhibiting bacterial cell wall synthesis. Hydrocortisone belongs to the class of corticosteroids. It blocks the production of prostaglandins (chemical messengers) that make the affected area red, swollen and itchy. On the other hand, Neomycin is an aminoglycoside antibiotic and prevents the synthesis of essential proteins required by bacteria to carry out vital functions. Polymyxin B, an antibiotic, destroys the bacterial membranes by binding to the phospholipids on the cell membranes of gram-negative bacteria. This process of binding causes the loss of essential metabolites in bacteria.

Your doctor will advise the appropriate dose that suits your infection. Common side effects of Neosporin-H Ointment 5 gm include itching, redness, dryness, and eye irritation. These side effects may not occur in every patient using this medication and differ individually. If the side effects persist longer or worsen, please seek a doctor's advice.

Let your doctor know if you are sensitive to Neosporin-H Ointment 5 gm or any other medications. Let your doctor know if you have kidney disease, myasthenia gravis (neuromuscular disease), or Parkinson's disease (a brain disorder that affects movement) before using Neosporin-H Ointment 5 gm. Avoid contact of the dispensing container with the eye, eyelids, fingers, and other surfaces to prevent contamination. Pregnant and breastfeeding women should consult their doctor before starting Neosporin-H Ointment 5 gm. 

Uses of Neosporin-H Ointment 5 gm

Neosporin-H Ointment 5 gm used in the treatment of bacterial eye infections. The detailed uses of Neosporin-H Ointment 5 gm are as follows:

  • Treating bacterial eye infections: Neosporin-H Ointment 5 gm helps to prevent and treat infections in the eye by killing the bacteria that cause the infection.
  • Relief from eye irritations: Neosporin-H Ointment 5 gm involves reducing the irritation, redness, and burning caused by infection, chemicals, heat, radiation, foreign bodies in the eye, and other eye conditions.
  • Reduce eye inflammation: Hydrocortisone in Neosporin-H Ointment 5 gm helps in reducing inflammation, providing relief from eye discomfort.

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication to ensure safety. • Lie down and tilt your head backwards. Pull your lower eyelid gently with your index finger to form a pocket. Instil the number of drops advised by the doctor into the pocket of the lower eyelid. Close your eyes for 1-2 minutes. • Avoid touching the dropper tip to prevent contamination.

Medicinal Benefits

Neosporin-H Ointment 5 gm treats bacterial eye infections. It comprises four medicines, namely Bacitracin, Hydrocortisone, Neomycin, and Polymyxin B. Bacitracin is a bacteriostatic medicine (stops the growth or reproduction of bacteria) and works by inhibiting the bacterial cell wall synthesis. Bacitracin is active against many gram-positive and some gram-negative bacteria. Hydrocortisone is a corticosteroid and blocks prostaglandins' production (chemical messengers) that make the affected area red, swollen and itchy. Neomycin is an aminoglycoside antibiotic and prevents the synthesis of essential proteins required by bacteria to carry out vital functions. Polymyxin B, an antibiotic, destroys the bacterial membranes by binding to the phospholipids on cell membranes of gram-negative bacteria. This process of binding causes the loss of essential metabolites in bacteria. It is bactericidal against most gram-negative bacteria and has no in-vitro activity against gram-positive bacteria.

How Neosporin-H Ointment 5 gm Works

Neosporin-H Ointment 5 gm is composed of four medicines: Bacitracin, Hydrocortisone, Neomycin, and Polymyxin B. Bacitracin is a bacteriostatic medicine (stops the growth or reproduction of bacteria). It works by inhibiting bacterial cell wall synthesis. Hydrocortisone belongs to the class of corticosteroids. It blocks the production of prostaglandins (chemical messengers) that make the affected area red, swollen and itchy. On the other hand, Neomycin is an aminoglycoside antibiotic and prevents the synthesis of essential proteins required by bacteria to carry out vital functions. Polymyxin B, an antibiotic, destroys the bacterial membranes by binding to the phospholipids on the cell membranes of gram-negative bacteria. This process of binding causes the loss of essential metabolites in bacteria.

Storage

• Store in a cool and dry place away from sunlight.• Keep out of sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Neosporin-H Ointment 5 gm

Use Neosporin-H Ointment 5 gm only as prescribed by the physician. Though it is unlikely to cause any harm if you have overdosed, it is advised not to exceed the recommended dose. Seek immediate medical attention if you experience any unusual symptoms.

Drug Warnings

Let your doctor know if you are sensitive to Neosporin-H Ointment 5 gm or any other medications.  Let your doctor know if you have any kidney disease, myasthenia gravis (neuromuscular disease), or Parkinson's disease (a brain disorder that affects movement) before using Neosporin-H Ointment 5 gm. Avoid contact of the dispensing container with the eye, eyelids, fingers, and other surfaces to prevent contamination. Let your doctor know if you plan to become pregnant or are already pregnant and a lactating mother. Avoid driving or operating machines since the administration of eye ointment may cause temporary blurred vision for a while after use. Neosporin-H Ointment 5 gm should be used for children only when advised by a doctor.

Drug-Drug Interactions

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HydrocortisoneIopamidol
Critical
HydrocortisoneMifepristone
Critical

Drug-Drug Interactions

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HydrocortisoneIopamidol
Critical
How does the drug interact with Neosporin-H Ointment 5 gm:
Taking Iopamidol and Neosporin-H Ointment 5 gm together can increase the risk of seizures, meningitis, and inflammation of the spinal membranes.

How to manage the interaction:
Taking Neosporin-H Ointment 5 gm with Iopamidol is not recommended, please consult your doctor before taking it. If you experience any symptoms , consult the doctor immediately. Do not stop using any medications without a doctor's advice.
HydrocortisoneMifepristone
Critical
How does the drug interact with Neosporin-H Ointment 5 gm:
Combining Mifepristone and Neosporin-H Ointment 5 gm can reduce the effects of Neosporin-H Ointment 5 gm.

How to manage the interaction:
Taking Neosporin-H Ointment 5 gm with Mifepristone is not recommended, consult a doctor before taking it. If you experience any symptoms, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
BacitracinEverolimus
Severe
How does the drug interact with Neosporin-H Ointment 5 gm:
Everolimus can cause kidney issues, and taking it with Neosporin-H Ointment 5 gm, can enhance the risk.

How to manage the interaction:
Although taking Neosporin-H Ointment 5 gm and Everolimus together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medication without consulting a doctor.
BacitracinHuman immunoglobulin
Severe
How does the drug interact with Neosporin-H Ointment 5 gm:
Taking Human immunoglobulin with Neosporin-H Ointment 5 gm, may raise the risk of kidney problems.

How to manage the interaction:
Taking Human immunoglobulin with Neosporin-H Ointment 5 gm together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
BacitracinHydroxycarbamide
Severe
How does the drug interact with Neosporin-H Ointment 5 gm:
Hydroxycarbamide when used in conjunction with Neosporin-H Ointment 5 gm may raise the risk of severe infections.

How to manage the interaction:
There may be a possibility of interaction between hydroxycarbamide with Neosporin-H Ointment 5 gm, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhoea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
BacitracinAmikacin
Severe
How does the drug interact with Neosporin-H Ointment 5 gm:
Coadministration of Amikacin with Neosporin-H Ointment 5 gm can increase the risk of developing side effects like hearing loss, difficulty breathing, or kidney problems.

How to manage the interaction:
Although taking amikacin and Neosporin-H Ointment 5 gm together can result in an interaction, it can be taken if a doctor has prescribed it. Consult a doctor if you experience ringing in the ears, difficulty breathing, vomiting, increased or decreased urination, swelling, muscle cramps, dizziness, or palpitations. Do not stop using any medications without talking to a doctor.
BacitracinPolymyxin b
Severe
How does the drug interact with Neosporin-H Ointment 5 gm:
Taking Polymyxin b and Neosporin-H Ointment 5 gm together can increase the risk of kidney and inner ear damage

How to manage the interaction:
Although taking Polymyxin b and Neosporin-H Ointment 5 gm together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience ringing in the ears, hearing loss, vertigo, nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, swelling, difficulty breathing, bone pain, muscle pain, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
BacitracinSirolimus
Severe
How does the drug interact with Neosporin-H Ointment 5 gm:
Co-administration of Neosporin-H Ointment 5 gm and Sirolimus can increase the risk or severity of Kidney problems.

How to manage the interaction:
Co-administration of Sirolimus with Neosporin-H Ointment 5 gm can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
BacitracinCarboplatin
Severe
How does the drug interact with Neosporin-H Ointment 5 gm:
Taking carboplatin and Neosporin-H Ointment 5 gm can increase the risk of nephrotoxicity(kidney damage).

How to manage the interaction:
Co-administration of carboplatin and Neosporin-H Ointment 5 gm can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any unusual symptoms consult the doctor. Do not discontinue any medications without a doctor's advice.
BacitracinClindamycin
Severe
How does the drug interact with Neosporin-H Ointment 5 gm:
Co-administration of Clindamycin with Neosporin-H Ointment 5 gm may increase the risk of kidney and/or nerve damage.

How to manage the interaction:
Although there is a possible interaction, clindamycin can be taken with Neosporin-H Ointment 5 gm if prescribed by the doctor. Consult the prescriber if you experience signs and symptoms of kidney damage such as sudden weight gain or weight loss, nausea, vomiting, fluid retention, loss of appetite, increased or decreased urination, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Let your doctor know if you develop seizures; hearing problems; or numbness, burning or tingling in your hands and feet. If you develop diarrhoea or vomiting during treatment with these medications, drink plenty of fluids to prevent dehydration, as dehydration may harm the kidney.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Do not rub your eyes even though some ophthalmic drugs make your eye itchy.
  • If you wear contact lenses: Clean and replace contact lenses more often. Never share contact lenses. Always remember to wash your hands before inserting and after removing the contact lens. 
  • Avoid staring at digital screens for longer durations. Rest your eyes every 20 minutes.
  • Avoid or limit the intake of alcohol and caffeine.
  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Know your allergy triggers, such as pollen, dust and other factors.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS
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Alcohol

Safe if prescribed

No interaction found/ established. Please consult your doctor before using Neosporin-H Ointment 5 gm.

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Pregnancy

Caution

It is advised to consult your doctor if you plan to conceive or already pregnant before starting Neosporin-H Ointment 5 gm.

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Breast Feeding

Caution

There are limited studies on how Neosporin-H Ointment 5 gm affects breastfed infants. Please consult your doctor before taking Neosporin-H Ointment 5 gm if you are breastfeeding.

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Driving

Caution

Neosporin-H Ointment 5 gm may cause side effects like temporary blurry vision, affecting your driving ability. Do not drive or operate machinery in such cases. Drive only when you are alert and have clear vision.

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Liver

Caution

Let your doctor know if you have any history of liver diseases or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing Neosporin-H Ointment 5 gm.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases. Your doctor will weigh the benefits and potential risks before prescribing Neosporin-H Ointment 5 gm.

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Children

Caution

Neosporin-H Ointment 5 gm should be used for children only If it is prescribed by a doctor.

Have a query?

FAQs

Neosporin-H Ointment 5 gm is used to treat bacterial infections of the external eye and uveitis (inflammation of the middle layer of the eye (uvea)).

Neosporin-H Ointment 5 gm consists Bacitracin, Neomycin, Hydrocortisone, and Polymyxin B. Neosporin-H Ointment 5 gm inhibits bacteria's growth by causing damage to its cell wall and prevents the synthesis of essential proteins required by bacteria to carry out its vital functions. It also relieves itchiness and redness caused by the infection.

Your doctor will decide the dose and duration of Neosporin-H Ointment 5 gm based on the severity of your infection. It is advised to use Neosporin-H Ointment 5 gm only for the prescribed period since long-term usage of Neosporin-H Ointment 5 gm may increase the severity of side effects. Prolonged use of Neosporin-H Ointment 5 gm can cause an overgrowth of other microorganisms like fungi and develop bacterial resistance.

Please do not stop using Neosporin-H Ointment 5 gm on your own, even if the symptoms are relieved. Your symptoms may improve before the infection is completely cured. Continue the usage of Neosporin-H Ointment 5 gm until your course advised by the doctor is finished.

Avoid the contact of dropper or tip with fingers, eyes, and eyelids when you use eye ointment or eye drops of Neosporin-H Ointment 5 gm. Topical eye products, when contaminated by patients with eye diseases, bacterial keratitis (an infection of the cornea) and ocular infections (eye infections), may occur, which result in vision loss.

If you use other eye ointments/drops along with Neosporin-H Ointment 5 gm, it is advised to maintain a gap of at least 5-10 minutes after each administration. Also, use eye drops before applying any ointments.

It is generally not recommended to apply cosmetic products to the affected area unless advised by the doctor.

Neosporin-H Ointment 5 gm can be applied to the affected areas in or around the eyes and skin to treat bacterial infections. However, it is essential to use separate tubes for eye and skin infections to avoid contamination and maintain the efficacy of the treatment. Using the same tube for both areas may introduce bacteria from one site to another, potentially leading to further complications. Always follow your doctor's guidance when using this medication for different areas.

You should use Neosporin-H Ointment 5 gm for as long as your doctor has prescribed, based on the severity of your condition. However, if your symptoms do not improve or worsen within 2 days after starting treatment, stop using Neosporin-H Ointment 5 gm and contact your doctor. If you use this medicine for longer than 10 days, you may need frequent vision tests to check the pressure inside your eyes. Always follow your doctor's instructions for the best results.

Neosporin-H Ointment 5 gm may cause common side effects, such as itching, redness, dryness, and eye irritation. Usually, these fade away with time. In case these side effects persist longer or worsen, please seek your doctor's advice.

Overusing Neosporin-H Ointment 5 gm may increase the risk of side effects (such as eye irritation, redness, or dryness) and contribute to antibiotic resistance, making the treatment less effective. Prolonged use of Neosporin-H Ointment 5 gm may also lead to decreased or blurred vision. To minimize these risks and get the potential benefits of Neosporin-H Ointment 5 gm, always follow the dosage and duration your doctor directs.

Neosporin-H Ointment 5 gm should be stored in a cool and dry place, away from direct light and moisture. Do not freeze it. Keep it out of reach of children.

Neosporin-H Ointment 5 gm is generally safe for short-term use on the skin to treat minor infections and inflammation. However, it should be used as directed by your doctor, as overuse or prolonged use may cause side effects like skin irritation. Please consult your doctor if you have any concerns about the safety of Neosporin-H Ointment 5 gm.

Neosporin-H Ointment 5 gm can be beneficial and harmful, depending on its use. It can effectively treat eye infections and inflammation, but improper use or overuse may lead to side effects. Following your doctor’s advice for safe and effective use is important.

Wash your hands thoroughly before applying Neosporin-H Ointment 5 gm to your eye to avoid contamination. Do not touch the tip of the ointment tube or allow it to touch your eye or any other surface. Tilt your head back, look upward, and create a pouch by pulling your lower eyelid down. Gently squeeze the tube to place a 1/2-inch strip of ointment into the pouch. Close your eye and roll your eyeball to help spread the medication. Avoid blinking or rubbing your eyes. After use, wipe the tip of the tube with a clean tissue and tightly close the cap.

Neosporin-H Ointment 5 gm should not be used by patients who are allergic to any of its ingredients. It should be avoided by individuals with fungal or viral eye infections, including herpes simplex. It is also not recommended for use by children under 18 years old.

To achieve the maximum benefits, you should apply Neosporin-H Ointment 5 gm at the time and for the duration prescribed by your doctor. It is typically applied every 3-4 hours, around the same time each day, until the prescribed course of treatment is complete.

Neosporin-H Ointment 5 gm is not recommended for treating pimples. It is specifically formulated for eye infections and may not be effective or safe for pimples. Additionally, Neosporin-H Ointment 5 gm may cause skin irritation or worsen acne. Please consult your doctor for the appropriate treatment of pimples.

Neosporin-H Ointment 5 gm specifically is not a steroid. However, it contains hydrocortisone, which is a steroid. Hydrocortisone is a corticosteroid that effectively reduces inflammation, while the other ingredients in Neosporin-H Ointment 5 gm are antibiotics. Therefore, Neosporin-H Ointment 5 gm has both steroid and antibiotic properties.

No, Neosporin-H Ointment 5 gm is not an antifungal. It is a combination of three antibiotics (Bacitracin, Neomycin, and Polymyxin B) and an anti-inflammatory (Hydrocortisone) used to treat bacterial infections and reduce eye inflammation. These ingredients do not address fungal infections.

Yes, Neosporin-H Ointment 5 gm is commonly used to treat minor skin and eye infections, including those caused by cuts, burns, and radiation. However, it is essential to consult a healthcare provider for an accurate diagnosis and appropriate treatment, especially for more profound or severe wounds.

Country of origin

India

Manufacturer/Marketer address

Stiefel India Ltd., 401& 402, A Wing, IV Floor, Floral Deck Plaza, Opp. Rolta Bhavan, Central MIDC Road, Andheri (East), Mumbai – 400093
Other Info - NEO0022

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Aug 6, 2025 | 9:56 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2004/50417slr011_neosporin_lbl.pdf
  2. https://www.webmd.com/drugs/2/drug-11001/neomycin-bacitracin-polymyxin-topical/details
  3. https://www.webmd.com/drugs/2/drug-161995/neosporin-neo-bac-polym-ophthalmic-eye/details
  4. https://www.drugs.com/mtm/bacitracin-neomycin-and-polymyxin-b-topical.html
  5. https://www.drugs.com/mtm/bacitracin-hydrocortisone-neomycin-and-polymyxin-b-ophthalmic.html
  6. https://www.webmd.com/drugs/2/drug-5986/neomycin-polymyxin-b-bacitracin-hydrocortisone-topical/details#:~:text=Reviews%20(0)-,Uses,by%20reducing%20swelling%20and%20itching.

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