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  3. Pargilin-0.5 Tablet 10's

Pargilin-0.5 Tablet 10's, Pack of 10 TABLETS
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Composition :

RASAGILINE-0.5MG

Manufacturer/Marketer :

East West Pharma India Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Pargilin-0.5 Tablet

Pargilin-0.5 Tablet is used alone or in combination with another medication to treat the symptoms of Parkinson's disease. Parkinson's disease is a condition in which regions of the brain gradually weaken over time. Parkinson's disease symptoms include involuntary shaking of certain body parts (tremors), sluggish movement, and stiff and inflexible muscles. In Parkinson's patients, there is a decrease in dopamine (a chemical messenger that is important for movement control) levels as the nerve cells that produce dopamine begin to die.

Pargilin-0.5 Tablet contains Rasagiline. It works by increasing the amount of dopamine, a chemical messenger needed to control movement in the brain. Thus, it helps treat the symptoms of Parkinson's disease.

Use Pargilin-0.5 Tablet as advised by your doctor. The most common side effects of Pargilin-0.5 Tablet are feeling sick, headaches, abdominal pain and high blood pressure. Most of these side effects of Pargilin-0.5 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Pargilin-0.5 Tablet or any other medicines, please inform your doctor. If you are a pregnant woman or nursing mother, do not consume Pargilin-0.5 Tablet without first consulting your doctor. Inform your doctor before using the Pargilin-0.5 Tablet if you have a history of hypotension, hypertension, liver or kindly impairments. To rule out any negative effects/interactions, keep your doctor informed about your health condition and all medications you use. Avoiding alcohol is recommended to rule out any possibility of side effects like dizziness. Pargilin-0.5 Tablet is not recommended in children below 12 years of age.

Uses of Pargilin-0.5 Tablet

Pargilin-0.5 Tablet is used in the treatment of Parkinson’s disease. The detailed use of Pargilin-0.5 Tablet is as follows:<br/>• Parkinson's Disease Management: Pargilin-0.5 Tablet helps to manage Parkinson's symptoms like tremors, stiffness, and slow movement by increasing dopamine levels in the brain, thereby improving motor function and enhancing mobility.<br/>

Directions for Use

• Take Pargilin-0.5 Tablet with or without food as advised by your doctor.• It is advised to take Pargilin-0.5 Tablet once daily; however, follow the doctor’s recommendation regarding the dosage and duration.• Swallow Pargilin-0.5 Tablet as a whole with a glass of water.• Do not crush, break, or chew it.

Medicinal Benefits

Pargilin-0.5 Tablet contains Rasagiline, an antiparkinson agent that is used in the treatment of Parkinson’s disease. In Parkinson’s patients, the nerve cells that produce dopamine (a chemical messenger that is important for movement control) begin to die. So, there is a decrease in dopamine levels. Pargilin-0.5 Tablet gets converted to dopamine in the brain and restores its levels. Thereby improving the symptoms of Parkinson’s disease.

How Pargilin-0.5 Tablet Works

Pargilin-0.5 Tablet contains Rasagiline. It works by increasing the amount of dopamine, a chemical messenger needed to control movement in the brain. Thus, it helps treat the symptoms of Parkinson's disease.
Side effects of Pargilin-0.5 Tablet
  • If you experience symptoms such as, involuntary movements, tongue thrusting, muscle spasms, abnormal postures or facial grimacing as a drug side effect, consult your doctor as they may adjust the dose if necessary or prescribe alternative medication.
  • Attend regular health check-ups to monitor your overall health and adjust treatment plans.
  • Take medications exactly as prescribed to minimize the risk of EPS.
  • Establish a consistent sleep schedule and create a relaxing sleep environment to improve sleep quality.
  • To decrease tension and anxiety, engage in relaxation practices like yoga, meditation, or deep breathing.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Do not stand up suddenly. Lie down and get up slowly only when you feel better.
  • Avoid alcohol and large meals.
  • Drink enough water before standing for long periods.
  • Exercise regularly; however, avoid exercising in extreme heat.
  • Eat small, low-carb meals.
  • Wear compression stockings.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
  • Weight loss without physical activity needs immediate medical attention.
  • Get a physical examination and blood tests done to identify factors causing weight loss that could be related to metabolism and thyroid function.
  • Avoid smoking and alcohol intake as it can alter your liver condition and increase your weight loss.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes of weight loss.
  • Talk to your dietician and consume food which can maintain ideal weight.
Here are the steps to manage Joint Pain caused by medication usage:
  • Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
  • Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
  • Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
  • Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.

What if I have taken an overdose of Pargilin-0.5 Tablet

Do not take more than the prescribed dose of Pargilin-0.5 Tablet as it may cause overdose. The symptoms of overdose include fainting, dizziness, irritability, drowsiness, severe headache, confusion, hyperactivity, restlessness or agitation, loss of coordination, cool/clammy skin, sweating, difficulty or slowed breathing and seizures (fits). If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Before taking the Pargilin-0.5 Tablet , let your doctor know about all your allergic or hypersensitivity reactions to medicines or food. Keep your doctor informed about your health condition and all your medications before taking Pargilin-0.5 Tablet to rule out any side effects. Inform your doctor if you are suffering from hypotension, psychosis (psychotic disorder) and hepatic impairment. Limit or avoid the consumption of caffeine or alcohol intake.

Drug-Drug Interactions

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RasagilineDuloxetine
Critical
RasagilineSelegiline
Critical

Drug-Drug Interactions

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RasagilineDuloxetine
Critical
How does the drug interact with Pargilin-0.5 Tablet:
Taking Pargilin-0.5 Tablet with Duloxetine can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Pargilin-0.5 Tablet and Duloxetine is not recommended as they can possibly result in an interaction, but they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, shivering, pain in the muscles, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting a doctor.
RasagilineSelegiline
Critical
How does the drug interact with Pargilin-0.5 Tablet:
Co-administration of Selegiline with Pargilin-0.5 Tablet can increase the risk of high blood pressure.

How to manage the interaction:
Although there is a possible interaction between Selegiline and Pargilin-0.5 Tablet, but can be taken together if prescribed by a doctor. However, if you experience confusion, hallucination (seeing or hearing things that do not exist), fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasms, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor right away. Do not discontinue any medications without consulting a doctor.
RasagilineDextromethorphan
Critical
How does the drug interact with Pargilin-0.5 Tablet:
Taking Pargilin-0.5 Tablet with Dextromethorphan can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Dextromethorphan with Pargilin-0.5 Tablet is not recommended as it can possibly result in an interaction, it can be taken if a doctor has advised it. If you notice any of these symptoms like confusion, hallucination, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, shaking, incoordination, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor. Do not discontinue any medications without consulting a doctor.
RasagilineErgotamine
Critical
How does the drug interact with Pargilin-0.5 Tablet:
Taking Ergotamine and Pargilin-0.5 Tablet together can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Pargilin-0.5 Tablet and Ergotamine is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm, stomach cramp, nausea, vomiting, and diarrhea contact your doctor right away. Do not discontinue any medications without first consulting your doctor.
RasagilineTranylcypromine
Critical
How does the drug interact with Pargilin-0.5 Tablet:
Taking tranylcypromine with Pargilin-0.5 Tablet can increase the risk severe high blood pressure.

How to manage the interaction:
Taking Tranylcypromine with Pargilin-0.5 Tablet is not recommended, as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and fainting, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
RasagilineTapentadol
Critical
How does the drug interact with Pargilin-0.5 Tablet:
Using tapentadol together with Pargilin-0.5 Tablet might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to severe side effects.

How to manage the interaction:
Taking tapentadol with Pargilin-0.5 Tablet is generally avoided, but can be taken only if prescribed by a doctor. However, if you experience confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, blurred vision, muscle spasm or stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea call a doctor right away. Do not discontinue any medications without consulting a doctor.
RasagilineDesvenlafaxine
Critical
How does the drug interact with Pargilin-0.5 Tablet:
Taking Pargilin-0.5 Tablet with Desvenlafaxine can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Desvenlafaxine with Pargilin-0.5 Tablet together can possibly result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucinations (seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting a doctor.
RasagilineOxcarbazepine
Critical
How does the drug interact with Pargilin-0.5 Tablet:
Combining Oxcarbazepine with Pargilin-0.5 Tablet can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Oxcarbazepine with Pargilin-0.5 Tablet is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience confusion, hallucination(seeing or hearing things that do not exist), seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasms, stomach cramps, nausea, vomiting, and diarrhoea, contact a doctor right away. Do not discontinue any medications without consulting a doctor.
RasagilineMethyldopa (racemic)
Critical
How does the drug interact with Pargilin-0.5 Tablet:
Taking Pargilin-0.5 Tablet and Methyldopa may increase the risk of high blood pressure and CNS effects.

How to manage the interaction:
Taking Pargilin-0.5 Tablet with Methyldopa is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. If you notice any of these symptoms like severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting, it's a good idea to reach out to your doctor right away. Do not discontinue any medications without first consulting your doctor.
RasagilineBuspirone
Critical
How does the drug interact with Pargilin-0.5 Tablet:
Combining Pargilin-0.5 Tablet with Buspirone can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Pargilin-0.5 Tablet with Buspirone is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience confusion, hallucination, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramps, nausea, vomiting, and loose stools, consult a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A balanced diet rich in vitamins, fibres, and minerals, such as grains and leafy greens, is essential for showing improvement in Parkinson's disease. In addition to this food, one should include dairy products, protein-rich foods like meat and beans, and solid fats like nuts, olive oil, fish, and eggs in their diet. However, limit your sugar intake.
  • Constipation is a common complaint among Parkinson's disease patients. Drinking more liquids and increasing fibre intake can help you overcome this problem.
  • Parkinson's disease is frequently caused by decreased bone thickness. Taking calcium and vitamin D supplements may help in this regard. However, before taking any supplements, consult with your doctor.
  • One should drink a lot of water as a person with this disease often feels dehydrated.

Habit Forming

Not enough scientific literature available around this hence it is best to consult your physician

Therapeutic Class

ANTIPARKINSON AGENTS

Pargilin-0.5 Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Limit or avoid alcohol consumption; alcohol consumption makes you feel sleepy or tired.

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Pregnancy

Caution

Pargilin-0.5 Tablet is not recommended for use in pregnancy unless clearly necessary. So, inform your doctor if you are pregnant or suspect pregnancy before taking this medicine. Your doctor will weigh the benefits and potential risks before prescribing Pargilin-0.5 Tablet .

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Breast Feeding

Caution

Pargilin-0.5 Tablet should not be used in nursing mothers unless clearly necessary. So, inform your doctor before taking this medicine if you are a nursing mother. Your doctor will weigh the benefits and potential risks before prescribing Pargilin-0.5 Tablet .

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Driving

Caution

Pargilin-0.5 Tablet may cause a reduction in mental attentiveness; hence, avoid driving or using machinery.

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Liver

Caution

Let your doctor know before receiving Pargilin-0.5 Tablet if you have liver disease or have a history of liver impairment/disorder. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Tell your doctor before receiving the Pargilin-0.5 Tablet if you have kidney problems or a history of liver diseases/conditions. Your doctor may adjust your dose depending upon your current kidney conditions.

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Children

Caution

Pargilin-0.5 Tablet is not recommended for use in children under 18 years of age.

Have a query?

FAQs

Pargilin-0.5 Tablet is used alone or in combination with another medication to treat the symptoms of Parkinson&amp;#039;s disease.

Pargilin-0.5 Tablet contains Rasagiline, which works by increasing the amount of dopamine, a chemical messenger needed to control movement in the brain. Thus, it helps to treat the symptoms of Parkinson&amp;#039;s disease.

Take Pargilin-0.5 Tablet medicine as prescribed by your doctor. Take one dose on a regular basis. Try to take the Pargilin-0.5 Tablet at the same time of day every day, as this will assist you in making sure to take them.

It is possible that a person may face unsteadiness or dizziness, particularly when they get up from a lying or sitting position while on treatment with Pargilin-0.5 Tablet . Getting up slowly may help.

A person dealing with Parkinson&amp;#039;s disease can notice an improvement in their condition after some weeks of starting the treatment.

Do not double the dosage to compensate for a missed one. You can skip the missed portion and take the next dosage at the standard time of the following day.

To ensure safe and effective treatment, take Pargilin-0.5 Tablet orally once a day, with or without food, and at the same time every day to maintain a consistent therapeutic level. Always follow the instructions on your prescription label carefully, and don't hesitate to ask your doctor or pharmacist to explain any part you don't understand. Adhere to these guidelines to take Pargilin-0.5 Tablet effectively and safely.

Pargilin-0.5 Tablet is generally well-tolerated, and most people taking the medication do not experience significant side effects. While some individuals may encounter mild side effects such as headaches, nausea, abdominal pain, or high blood pressure, these effects are usually temporary and resolve on their own over time. If you do experience any side effects, rest assured that your doctor is available to provide guidance and support to ensure your comfort and well-being.

Pargilin-0.5 Tablet falls under the category of Monoamine Oxidase B (MAO-B) inhibitors, a specific class of medications that work by blocking the action of an enzyme called monoamine oxidase B (MAO-B) in the brain. This medication is specifically used for the treatment of Parkinson's disease, helping to manage its symptoms and improve the quality of life for those affected.

Yes, smoking can reduce the levels of Rasagiline in the blood, potentially making it less effective. Please tell your doctor if you smoke or intend to stop smoking while taking Pargilin-0.5 Tablet .

To maximize the benefits of Pargilin-0.5 Tablet , it's essential to be mindful of your diet. Focus on avoiding foods rich in tyramine, such as aged cheeses, fermented foods, red wine, soy products, and certain fruits like avocado and bitter orange, as they can cause a sudden increase in blood pressure. Additionally, avoiding tobacco is a great idea, as it can reduce the effectiveness of it. By following your doctor's personalized dietary recommendations, you'll be well on your way to getting the most out of your treatment.

Pargilin-0.5 Tablet is a valuable treatment option, and while it's essential to acknowledge potential risks, it's also important to emphasize proactive measures for minimizing them. There is a possible link between Pargilin-0.5 Tablet and an increased risk of melanoma, a type of skin cancer. However, you can significantly reduce this risk by being vigilant about your skin health. Regularly monitor your skin for any unusual changes, and don't hesitate to consult your doctor if you notice anything suspicious. Additionally, scheduling regular dermatological check-ups while using Rasagiline can provide added peace of mind and catch any potential issues early.

Pargilin-0.5 Tablet may cause low blood pressure when standing (orthostatic hypotension), leading to dizziness or light-headedness, affecting your ability to drive or operate heavy machinery. If you experience these symptoms, avoid driving unless you are fully alert.

Fainting after getting up from bed may be due to low blood pressure (orthostatic hypotension), a possible side effect of Pargilin-0.5 Tablet . If you experience this, sit up slowly before standing and stay hydrated to reduce the risk. Please consult the doctor if this symptom persists or worsens.

Pargilin-0.5 Tablet may interact with certain cold and flu medications, including those containing decongestants like pseudoephedrine or phenylephrine, which can raise blood pressure. Therefore, please consult your doctor before taking cold and flu medications with Pargilin-0.5 Tablet to ensure safety.

Country of origin

India

Manufacturer/Marketer address

No. 10, 2nd Cross, Maravaneri, Salem - 636007, Tamil Nadu.
Other Info - PAR0931

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:35 AM IST

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Reference

  1. https://www.webmd.com/drugs/2/drug-144380/rasagiline-oral/details
  2. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3721659/
  3. https://www.nhs.uk/conditions/parkinsons-disease/

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