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Manufacturer/Marketer :

Lupin Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About R-Cinex 600 Tablet

R-Cinex 600 Tablet is used to treat tuberculosis in children. Tuberculosis is an infectious disease that mainly affects the lungs but can also spread to other body parts such as the kidneys, brain, spine, and bone marrow.
 
R-Cinex 600 Tablet contains Rifampicin, and Isoniazid. Rifampicin inhibits DNA-dependent RNA polymerase activity in the bacteria. Isoniazid inhibits the biosynthesis of mycolic acid, which is the major component of the cell wall. Together, R-Cinex 600 Tablet kills Mycobacterium tuberculosis which causes TB (tuberculosis).
 
In some cases, R-Cinex 600 Tablet may cause side effects such as nausea, vomiting, diarrhoea, stomach pain, and loss of appetite. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to the doctor if the side effects persist or worsen.
 
Let your doctor know if your child is allergic to any of the components in R-Cinex 600 Tablet. Keep your doctor informed about your child's health condition and medications to rule out any side effects/interactions.

Uses of R-Cinex 600 Tablet

R-Cinex 600 Tablet is used in the treatment of Tuberculosis. The detailed uses of R-Cinex 600 Tablet are as follows:<br/>• Treatment of Active Tuberculosis (TB): R-Cinex 600 Tablet is used in combination therapy to treat active TB infections in children. Rifampicin and Isoniazid work synergistically to kill Mycobacterium tuberculosis by disrupting bacterial protein synthesis and cell wall formation, helping reduce symptoms like persistent cough, fever, and weight loss.<br/>• Latent Tuberculosis Infection (LTBI): R-Cinex 600 Tablet is used in children who have been exposed to TB but do not yet show symptoms. It helps prevent the progression from latent to active TB, especially in high-risk groups such as those with weakened immune systems.<br/>• Tuberculous Meningitis and Disseminated TB: R-Cinex 600 Tablet may be part of a broader regimen to treat severe forms of TB, such as TB meningitis or miliary TB, due to its ability to penetrate the central nervous system and systemic circulation effectively.<br/>• Preventive Therapy in High-Risk Pediatric Contacts: R-Cinex 600 Tablet is used as a prophylactic treatment for children who have been in close contact with TB-positive individuals, aiming to stop the infection before it becomes active.<br/>

Directions for Use

• R-Cinex 600 Tablet should be administered one hour before or two hours after meals, or as directed by the doctor.• Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.• Administer the prescribed dose to the child using the measuring cup/dosing syringe.• Shake well before use.

Medicinal Benefits

R-Cinex 600 Tablet belongs to the group of medicines called anti-tuberculosis drugs primarily used to treat and prevent tuberculosis. R-Cinex 600 Tablet contains two anti-mycobacterial agents, Rifampicin and Isoniazid. Rifampicin inhibits DNA-dependent RNA polymerase activity in the bacteria. Isoniazid inhibits the biosynthesis of mycolic acid, which is the major component of the cell wall. Together, R-Cinex 600 Tablet kills Mycobacterium tuberculosis which causes TB (tuberculosis).

How R-Cinex 600 Tablet Works

R-Cinex 600 Tablet contains Rifampicin, and Isoniazid. Rifampicin inhibits DNA-dependent RNA polymerase activity in the bacteria. Isoniazid inhibits the biosynthesis of mycolic acid, which is the major component of the cell wall. Together, R-Cinex 600 Tablet kills Mycobacterium tuberculosis which causes TB (tuberculosis).

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of R-Cinex 600 Tablet

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of R-Cinex 600 Tablet may include altered sensorium, generalized tonic-clonic seizures, renal and hepatic dysfunctions, and severe metabolic acidosis. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

Do not give R-Cinex 600 Tablet to the child if he/she is allergic to any of the components in R-Cinex 600 Tablet, if he/she has acute liver disease, drug-induced liver disease, if the child has experienced liver damage linked to rifampicin or isoniazid, or if the child is taking anti-fungal (voriconazole) or medicines for HIV infection (protease inhibitors). R-Cinex 600 Tablet may cause liver damage; consult your doctor if the child experiences symptoms such as unexplained loss of appetite, nausea, vomiting, jaundice, dark urine, persistent fatigue for more than 3 days, abdominal pain and tenderness. Consult a doctor if your child gets flu-like symptoms such as headache, fever, or muscle ache. Inform the doctor if your child has HIV infection, epilepsy, psychiatric disorder, diabetes, porphyria, phenylketonuria (metabolic disorder), peripheral neuropathy (tingling sensation in hands and feet), kidney or liver problems, if your child is allergic to ethionamide or niacin (nicotinic acid), or if your child is taking cortisone or any cortisone-like drug. 

Drug-Drug Interactions

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IsoniazidLomitapide
Critical

Drug-Drug Interactions

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IsoniazidLomitapide
Critical
How does the drug interact with R-Cinex 600 Tablet:
When Lomitapide is taken with R-Cinex 600 Tablet, R-Cinex 600 Tablet may increase the blood levels of lomitapide which leads to side effects.

How to manage the interaction:
Taking R-Cinex 600 Tablet with Lomitapide is not recommended but can be taken if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, exhaustion, nausea, vomiting, dark urine, light stools, and skin or eye yellowing, decreased hunger, consult the doctor.
How does the drug interact with R-Cinex 600 Tablet:
When Lovastatin is taken with R-Cinex 600 Tablet, can increase the risk of myopathy (muscles problems), including rhabdomyolysis (a condition that causes your muscles to break down, which leads to muscle death).

How to manage the interaction:
Taking R-Cinex 600 Tablet with Lovastatin is not recommended but can be taken if a doctor has prescribed it.
How does the drug interact with R-Cinex 600 Tablet:
When R-Cinex 600 Tablet is taken with Regorafenib, it can increase the levels of Regorafenib leading to side effects.

How to manage the interaction:
Taking Regorafenib with R-Cinex 600 Tablet is not recommended, it taken can be taken if prescribed by the doctor.
How does the drug interact with R-Cinex 600 Tablet:
Taking darunavir with R-Cinex 600 Tablet can decrease the blood levels of darunavir, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between darunavir and R-Cinex 600 Tablet, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with R-Cinex 600 Tablet:
Taking pirfenidone with R-Cinex 600 Tablet can reduce the levels and effects of pirfenidone

How to manage the interaction:
Although there is an interaction between pirfenidone and R-Cinex 600 Tablet, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with R-Cinex 600 Tablet:
Taking Voriconazole with R-Cinex 600 Tablet can increase blood level of Voriconazole.

How to manage the interaction:
Although there is an interaction between Voriconazole with R-Cinex 600 Tablet, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with R-Cinex 600 Tablet:
When ranolazine is taken with R-Cinex 600 Tablet, it can reduce the blood levels and effects of ranolazine.

How to manage the interaction:
Although there is an interaction between ranolazine and R-Cinex 600 Tablet, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with R-Cinex 600 Tablet:
When Indinavir is taken with R-Cinex 600 Tablet, it can reduce the blood levels and effects of Indinavir.

How to manage the interaction:
Although there is an interaction between indinavir and R-Cinex 600 Tablet, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
RifampicinSaquinavir
Critical
How does the drug interact with R-Cinex 600 Tablet:
Taking saquinavir with R-Cinex 600 Tablet can increase the risk or severity of side effects.

How to manage the interaction:
Although there is an interaction between pyrazinamide and R-Cinex 600 Tablet, they can be taken together if prescribed by a doctor. However, if you experience fever, stomach pain, less desire to eat, nausea, yellowing of the skin or eyes, or dark urine, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
IsoniazidMipomersen
Severe
How does the drug interact with R-Cinex 600 Tablet:
Taking R-Cinex 600 Tablet and Mipomersen can increase the risk and severity of side effects of liver.

How to manage the interaction:
Although taking R-Cinex 600 Tablet and Mipomersen together can cause an interaction, it can be taken if a doctor has suggested it. If you notice any of these symptoms -fatigue, decreased hunger, nausea, vomiting, abdominal discomfort, dark urine, pale feces, yellowing of the skin or eyes, joint pain or swelling, fever, chills, unusual bleeding or bruises, skin rash, itching, and/or skin itchiness, please contact a doctor right away. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Pineapple juice might help soothe the symptoms of cough and cold. It also has anti-inflammatory and mucolytic properties.
  • Foods rich in vitamin C, such as kiwi, broccoli, and bell pepper, help improve the immune system. 
  • Avoid processed and fried foods.
  • Warm ginger tea or warm soup can help in providing relief from a cough.

Habit Forming

No

Therapeutic Class

ANTI- TUBERCULOSIS
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Alcohol

Not applicable

-

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Pregnancy

Not applicable

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Breast Feeding

Not applicable

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Driving

Not applicable

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Liver

Consult your doctor

Please consult the doctor if your child has a liver impairment or if you have any concerns regarding this.

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Kidney

Consult your doctor

Please consult the doctor if your child has kidney problems.

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Children

Safe if prescribed

R-Cinex 600 Tablet is safe for children if prescribed by the doctor. Your doctor may prescribe the dose and duration based on the child's condition and age.

Have a query?

FAQs

R-Cinex 600 Tablet is used to treat Tuberculosis.

R-Cinex 600 Tablet works by killing Mycobacterium tuberculosis which causes TB (tuberculosis).

R-Cinex 600 Tablet may cause reddish-orange discolouration of body fluids such as tears, sputum and urine; this is not harmful and does not require medical attention. However, consult your doctor if you have any concerns.

R-Cinex 600 Tablet might stain soft contact lenses. The child should use spectacles and avoid wearing contact lens while taking R-Cinex 600 Tablet.

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India Country of Origin: India
Other Info - RCI0007

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