Retagil Plus 100mg/325mg Tablet is a combination medication that belongs to the analgesic medication class. It is widely used in the treatment of acute and chronic pain, fever, headache, joint pains, dysmenorrhea (period pain), postoperative pain, toothache after dental extraction, and myalgia (muscle pain). Pain is a widely used term used to describe an unpleasant feeling or discomfort. It ranges from mild to severe. The severity of the pain depends on the underlying condition. Inflammation is the immune system's natural response to injury or infection.

Retagil Plus 100mg/325mg Tablet contains flupirtine and paracetamol. Flupirtine is an analgesic (non-opioid analgesic) which works by blocking the transmission of pain signals to the brain to lower pain perception. Paracetamol is an analgesic (pain reliever) and an antipyretic (fever reducer), which works by blocking the release of certain chemical messengers that cause fever and pain. Thus Retagil Plus 100mg/325mg Tablet alleviates pain and other associate conditions.

Use Retagil Plus 100mg/325mg Tablet as directed by the physician only. The dose and duration of the medication depend on your condition and its severity. The common side effects of Retagil Plus 100mg/325mg Tablet include nausea, vomiting, wind, abdominal discomfort, diarrhoea, constipation, heartburn, drowsiness, dizziness, headache, and depression. Most of these side effects of Retagil Plus 100mg/325mg Tablet are temporary, do not require medical attention, and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Before taking Retagil Plus 100mg/325mg Tablet, inform your doctor if you are allergic to flupirtine, paracetamol, or other ingredients. Besides, inform your doctor if you are pregnant, breastfeeding, or have any pre-existing conditions such as liver diseases such as hepatic encephalopathy (loss of brain function due to liver damage), chronic alcoholism, or cholestasis (reduced bile flow), renal impairment, myasthenia gravis (chronic neuromuscular disease), or heart diseases. If Retagil Plus 100mg/325mg Tablet is given in patients with liver diseases, liver function should be monitored closely. Retagil Plus 100mg/325mg Tablet causes drowsiness and dizziness, so drive only if you are alert. Retagil Plus 100mg/325mg Tablet is not recommended for children younger than six years old.

Retagil Plus 100mg/325mg Tablet contains flupirtine (non-opioid analgesic) and paracetamol (analgesic and antipyretic). Flupirtine works by blocking the glutamate receptors that are involved in producing pain signals. It also has muscle relaxant properties. Paracetamol acts as an analgesic and antipyretic by inhibiting the release of prostaglandins (chemical mediators) that cause pain, inflammation, and fever. Altogether provide relief from pain and associated symptoms.

Avoid using Retagil Plus 100mg/325mg Tablet if you are allergic to analgesics or painkillers. People with liver diseases, kidney diseases, and elderly people above 65 years of age may require dose adjustments. If Retagil Plus 100mg/325mg Tablet is given to patients with liver impairment, liver function should be closely monitored. It is advised to discontinue use if you notice any signs of liver damage such as nausea, vomiting, yellowed skin and eyes (jaundice), abdominal pain, loss of appetite, itchy skin, and dark-coloured urine, etc.