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  3. ROPIN 0.75% INJECTION 20ML

ROPIN 0.75% INJECTION 20ML, Pack of 1
ROPIN 0.75% INJECTION 20ML, Pack of 1
ROPIN 0.75% INJECTION 20ML, Pack of 1
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Synonym :

ROPIVACAINE

Composition :

ROPIVACAINE HYDROCHLORIDE-0.75%W/V

Manufacturer/Marketer :

Neon Laboratories Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About ROPIN 0.75% INJECTION

ROPIN 0.75% INJECTION belongs to the class of local anaesthetic medications. It is indicated in adults for producing local or regional anaesthesia for surgery and acute pain management. Anesthesia is a medical procedure that prevents pain and discomfort during surgical or medical procedures. Pain is a symptom triggered by the nervous system, which causes uncomfortable sensations in the body. The tolerance level of pain might vary from person to person.

ROPIN 0.75% INJECTION contains Ropivacaine Hydrochloride. It works by blocking the transmission of pain signals from the nerves to the brain.

ROPIN 0.75% INJECTION is administered only in a hospital setting by an anaesthetist. It may occasionally cause undesirable effects during the medical procedure like hypotension, nausea, vomiting, bradycardia (slow heart rate), fever, pain, postoperative complications, anaemia, paresthesia (Pins and needles), headache, pruritus (itching), and back pain. Any problems that arise during your procedure will be promptly addressed by your anaesthetist.

ROPIN 0.75% INJECTION is recommended not to use if you are hypersensitive to Ropivacaine Hydrochloride or other similar anaesthetics. So, before taking ROPIN 0.75% INJECTION, let your doctor know about all your medical conditions, sensitivities, and all medications you are using. Also, let your doctor know if you are pregnant or breastfeeding. The safety and efficacy of ropivacaine in pediatric patients have not been established. Patients should not drive or operate heavy machinery for at least 24 hours after receiving Ropivacaine Hydrochloride.

Uses of ROPIN 0.75% INJECTION

ROPIN 0.75% INJECTION is used for Surgical Anesthesia and Acute Pain Management. The detailed uses of ROPIN 0.75% INJECTION are as follows:<br/>• Surgical Anesthesia: ROPIN 0.75% INJECTION provides surgical anesthesia by blocking nerve signals, benefiting patients with effective pain relief during procedures like cesarean section.<br/>• Acute Pain Management: ROPIN 0.75% INJECTION manages acute pain by providing epidural infusion or local infiltration, alleviating postoperative or labor pain for patients.<br/>

Directions for Use

• Your doctor will tailor the exact timing and dosage of ROPIN 0.75% INJECTION to suit your treatment plan and response to therapy.• ROPIN 0.75% INJECTION is given by the doctor or nurse in a healthcare setting.• Do not self-administer.

Medicinal Benefits

ROPIN 0.75% INJECTION contains Ropivacaine Hydrochloride, which belongs to the anaesthetics class used for surgical anaesthesia. It is indicated in adults to produce local or regional anaesthesia for surgery and acute pain management. It works by blocking the transmission of pain signals from the nerves to the brain. This helps to decrease the sensation of pain.

How ROPIN 0.75% INJECTION Works

ROPIN 0.75% INJECTION contains Ropivacaine Hydrochloride. It works by blocking the transmission of pain signals from the nerves to the brain.

Storage

Store in a cool and dry place away from sunlight
Side effects of Ropin 0.75% Injection 20ml
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Managing back pain as a side effect of medication requires a combination of self-care techniques, lifestyle modifications, and medical interventions. Here are the steps:
  • Talk to your doctor about your back pain and potential medication substitutes or dose changes.
  • Try yoga or Pilates and other mild stretching exercises to increase flexibility and strengthen your back muscles.
  • To lessen the tension on your back, sit and stand upright and maintain proper posture.
  • To alleviate discomfort and minimize inflammation, apply heat or cold packs to the afflicted area.
  • Under your doctor's supervision, think about taking over-the-counter painkillers like acetaminophen or ibuprofen.
  • Make ergonomic adjustments to your workspace and daily activities to reduce strain on your back.
  • To handle tension that could make back pain worse, try stress-reduction methods like deep breathing or meditation.
  • Use pillows and a supportive mattress to keep your spine in the right posture as you sleep.
  • Back discomfort can worsen by bending, twisting, and heavy lifting.
  • Speak with a physical therapist to create a customized training regimen to increase back strength and flexibility.
Here are the steps to manage the medication-triggered Tachycardia (Fast Heart Rate):
  • Contact your doctor immediately if you're experiencing a fast heart rate, palpitations, or other heart-related symptoms. This is crucial to determine whether the symptoms are related to your medication.
  • Your doctor may need to adjust your medication regimen to alleviate the fast heart rate symptoms. This could involve changing the medication, reducing the dosage, or adding new medications to counteract the side effects.
  • Follow your doctor's advice on monitoring your heart rate and blood pressure. This will help track any changes and ensure your heart rate returns normal.
  • If you experience severe symptoms such as chest pain, dizziness, or shortness of breath, seek immediate medical attention. These symptoms can indicate a more serious condition that requires prompt treatment.
  • Change positions or take a break from activity to relieve symptoms.
  • Avoid postures that put a lot of pressure on just one area of the body.
  • If you have vitamin deficiency, take supplements or change your diet.
  • Exercise regularly like cycling, walking or swimming.
  • Avoid sitting with your legs crossed.
  • Clench and unclench your fists and wiggle your toes.
  • Massage the affected area.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.

What if I have taken an overdose of ROPIN 0.75% INJECTION

As ROPIN 0.75% INJECTION is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly.

Drug Warnings

ROPIN 0.75% INJECTION is not recommended in individuals with known hypersensitivity to ropivacaine or other amide-type local anaesthetic medication. So, tell your doctor about your medical conditions, sensitivities, and prescriptions. Inform your doctor if you are pregnant or breastfeeding. Ropivacaine's safety and efficacy in pediatric patients have not been established. After receiving Ropivacaine Hydrochloride, patients should not drive or operate heavy machinery for at least 24 hours. ROPIN 0.75% INJECTION may cause cardiac arrhythmia or cardiac arrest in some patients. Hence, careful monitoring is recommended during the treatment.

Drug-Drug Interactions

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RopivacaineGlyceryl trinitrate
Severe
RopivacaineRasburicase
Severe

Drug-Drug Interactions

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RopivacaineGlyceryl trinitrate
Severe
How does the drug interact with Ropin 0.75% Injection 20ml:
Coadministration of Ropin 0.75% Injection 20ml and glyceryl trinitrate has the potential to induce methemoglobinemia (a rare condition where red blood cells are unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although taking Ropin 0.75% Injection 20ml and glyceryl trinitrate together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as gray discoloration of the skin, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult your doctor immediately. Do not discontinue any medications without first consulting your doctor.
RopivacaineRasburicase
Severe
How does the drug interact with Ropin 0.75% Injection 20ml:
Taking rasburicase with Ropin 0.75% Injection 20ml can increase the risk of methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
There may be a possibility of interaction between Rasburicase and Ropin 0.75% Injection 20ml, but it can be taken if prescribed by a doctor. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, tiredness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
RopivacainePhenobarbital
Severe
How does the drug interact with Ropin 0.75% Injection 20ml:
Taking Phenobarbital with Ropin 0.75% Injection 20ml can increase the risk of methemoglobinemia (a rare condition that can lead to oxygen deprivation in tissues).

How to manage the interaction:
Although taking Phenobarbital and Ropin 0.75% Injection 20ml together can cause an interaction, it can be taken if a doctor has suggested it. Seek immediate medical attention if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without a doctor's advice.
RopivacainePhenazopyridine
Severe
How does the drug interact with Ropin 0.75% Injection 20ml:
Taking phenazopyridine with Ropin 0.75% Injection 20ml can increase the risk of methemoglobinemia(a blood disorder in which too little oxygen is delivered to the cells).

How to manage the interaction:
Taking Phenazopyridine with Ropin 0.75% Injection 20ml together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience symptoms such as gray discoloration of the skin, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult your doctor immediately. Do not discontinue any medications without first consulting your doctor.
RopivacaineSulfasalazine
Severe
How does the drug interact with Ropin 0.75% Injection 20ml:
Coadministration of Sulfasalazine with Ropin 0.75% Injection 20ml can increase the risk of methemoglobinemia, (a rare red blood cell condition where the oxygen-carrying capacity decreases).

How to manage the interaction:
Although taking Ropin 0.75% Injection 20ml and sulfasalazine together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
RopivacaineNitroprusside
Severe
How does the drug interact with Ropin 0.75% Injection 20ml:
Co-administration of Ropin 0.75% Injection 20ml and Nitroprusside can rarely cause methemoglobinemia(a rare condition that can reduce oxygen-carrying capacity of the blood).

How to manage the interaction:
Co-administration of Ropin 0.75% Injection 20ml and Nitroprusside can lead to an interaction, but it can be taken if your doctor advises. However, contact your doctor immediately if you experience any symptoms like discoloration of the skin, nausea, headache, dizziness, shortness of breath, or irregular heartbeat. Do not discontinue any medications without consulting your doctor.
RopivacaineIsosorbide dinitrate
Severe
How does the drug interact with Ropin 0.75% Injection 20ml:
Taking isosorbide dinitrate with Ropin 0.75% Injection 20ml may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although taking isosorbide dinitrate and Ropin 0.75% Injection 20ml together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
RopivacaineCyclophosphamide
Severe
How does the drug interact with Ropin 0.75% Injection 20ml:
Co-administration of Ropin 0.75% Injection 20ml with Cyclophosphamide can cause methemoglobinemia (low levels of oxygen in the blood).

How to manage the interaction:
Although there is a possible interaction between Ropin 0.75% Injection 20ml and Cyclophosphamide, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
RopivacaineDapsone
Severe
How does the drug interact with Ropin 0.75% Injection 20ml:
Taking Dapsone with Ropin 0.75% Injection 20ml can increase the risk of a condition called methemoglobinemia. (blood disorder in which too little oxygen is delivered to the cells).

How to manage the interaction:
Although there is a possible interaction between Dapsone and Ropin 0.75% Injection 20ml, you can take these medicines together if prescribed by a doctor. However, if you experience headache, dizziness, shortness of breath, or a rapid heartbeat contact a doctor immediately. Do not stop using any medications without consulting a doctor.
RopivacaineBupivacaine
Severe
How does the drug interact with Ropin 0.75% Injection 20ml:
Combining Ropin 0.75% Injection 20ml with Bupivacaine can have additive toxic effects, so using them together increases the risk of serious side effects like methemoglobinemia (a condition that can deprive tissues and organs of oxygen), reactions in the central nervous system (e.g-convulsions, unconsciousness, coma, respiratory arrest), and cardiovascular disorders (e.g- low blood pressure, heart block, irregular heart rhythm).

How to manage the interaction:
Although there is a possible interaction between Ropin 0.75% Injection 20ml and Bupivacaine, you can take these medicines together if prescribed by a doctor. However, if you experience pale, grey, or blue-coloured skin, headache, rapid heart rate, shortness of breath, lightheadedness, or fatigue, consult a doctor. Do not stop using any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

GENERAL ANESTHETICS

ROPIN 0.75% INJECTION Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

You are recommended to avoid alcohol consumption with ROPIN 0.75% INJECTION.

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Pregnancy

Caution

Inform your doctor before receiving the ROPIN 0.75% INJECTION if you are pregnant or planning to be pregnant. Your doctor will prescribe only if clinically needed if the benefits outweigh the risks.

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Breast Feeding

Caution

ROPIN 0.75% INJECTION may be excreted into the breast milk. Your doctor may suggest you stop breastfeeding for a certain period.

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Driving

Unsafe

Patients should not drive or operate heavy machinery for at least 24 hours after receiving ROPIN 0.75% INJECTION.

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Liver

Caution

Since the liver metabolizes amide-type local anaesthetics like ropivacaine, patients with liver disease should use ROPIN 0.75% INJECTION with caution, especially if they are taking repeat doses. Individuals with severe liver disease are more likely to experience toxic plasma concentrations due to their impaired ability to metabolize local anaesthetics.

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Kidney

Caution

Since the kidneys are known to excrete this medication and its metabolites, patients with impaired renal function may be more vulnerable to toxic reactions from ROPIN 0.75% INJECTION. Inform your doctor if you have kidney problems.

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Children

Caution

The safety and efficacy of ropivacaine hydrochloride in pediatric patients have not been established.

Have a query?

FAQs

ROPIN 0.75% INJECTION is used for Surgical Anesthesia and Acute Pain Management.

ROPIN 0.75% INJECTION contains Ropivacaine Hydrochloride. It works by blocking the transmission of pain signals from the nerves to the brain.

ROPIN 0.75% INJECTION may affect your heart rhythm. Disturbances of the heart rhythm are very common. Your anaesthetist will quickly deal with any problems that arise during your operation.

Country of origin

INDIA

Manufacturer/Marketer address

140, Damji Samji Industrial Complex, Mahakali Caves Rd., Andheri(East), Mumbai-93.
Other Info - ROP0010

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 18, 2025 | 9:22 AM IST

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Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2006/020533s014lbl.pdf
  2. https://www.pfizermedicalinformation.com/en-us/patient
  3. https://labeling.pfizer.com/ShowLabeling.aspx?id=4594

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