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  3. Samtica 500 mg Tablet 60's

Samtica 500 mg Tablet 60's, Pack of 1 Tablet
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Synonym :

ABIRATERONE ACETATE

Composition :

ABIRATERONE-500MG

Manufacturer/Marketer :

Samarth Life Sciences Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Samtica 500 mg Tablet 60's

Samtica 500 mg Tablet 60's belongs to the group of medicines called androgen biosynthesis inhibitors that is indicated in combination with prednisone or prednisolone to treat prostate cancer in adult men that have spread to other body parts.

Samtica 500 mg Tablet 60's contains ‘Abiraterone’ that works by stopping the body from making testosterone, thereby slowing the growth of prostate cancer.

In some cases, Samtica 500 mg Tablet 60's may cause common side effects such as diarrhoea, urinary tract infection, high blood pressure, low blood potassium, and oedema. If any of the side effects persist or worsen, consult your doctor.

Samtica 500 mg Tablet 60's is not for use in women, children, and adolescents. Samtica 500 mg Tablet 60's should not be given in combination with Ra-233 (a radioactive isotope used to treat prostate cancer) due to the increased risk of bone fracture or death. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Uses of Samtica 500 mg Tablet 60's

Samtica 500 mg Tablet 60's is used in the treatment of prostate cancer. The detailed uses of Samtica 500 mg Tablet 60's are as follows:<br/>• Treats advanced prostate cancer: Samtica 500 mg Tablet 60's lowers levels of certain hormones (androgens) that fuel the growth of prostate cancer cells.<br/>• Slows cancer progression: Samtica 500 mg Tablet 60's helps delay the spread and worsening of prostate cancer.<br/>• Improves overall management of prostate cancer: Samtica 500 mg Tablet 60's is often used along with other medicines to enhance treatment effectiveness.<br/>

Directions for Use

• Samtica 500 mg Tablet 60's can be taken on an empty stomach, i.e., 1 hour before or 2 hours after food. • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.• Swallow Samtica 500 mg Tablet 60's as a whole with a glass of water.• Do not chew, crush or break it.

Medicinal Benefits

Samtica 500 mg Tablet 60's belongs to the group of medicines called androgen biosynthesis inhibitors, indicated in combination with prednisone or prednisolone to treat prostate cancer in adult men that have spread to other body parts. Samtica 500 mg Tablet 60's contains ‘Abiraterone’ that works by stopping the body from making testosterone, thereby slowing the growth of prostate cancer. It is indicated in patients with metastatic castration-resistant prostate cancer (CRPC) who have received prior chemotherapy containing docetaxel and metastatic high-risk castration-sensitive prostate cancer (CSPC). Samtica 500 mg Tablet 60's is prescribed in the early stages of the disease, where it is still responding to hormone therapy. It is used with androgen deprivation therapy (a treatment that lowers testosterone).

How Samtica 500 mg Tablet 60's Works

Samtica 500 mg Tablet 60's contains ‘Abiraterone’ that works by stopping the body from making testosterone, thereby slowing the growth of prostate cancer.

Storage

Store in a cool and dry place away from sunlight
Side effects of Samtica 500 mg Tablet
  • If you have discomfort, illness, or unease after taking medication, seek medical attention.
  • Your treatment plan may be modified, including adjusting the dosage, substituting with an alternative medication, or discontinuing the medication. Additionally, certain lifestyle changes may be recommended to help manage symptoms.
  • To manage discomfort, follow your doctor's advice, like getting plenty of rest, or staying hydrated, and practising stress-reducing techniques.
  • Track your symptoms regularly and report any changes or concerns to your healthcare provider to manage the discomfort effectively.
  • Talk to your doctor about oral potassium supplements.
  • Eat potassium rich foods such as bananas, avocados, oranges, dark leafy greens, beans and peas, fish, spinach, milk and tomatoes.
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.

What if I have taken an overdose of Samtica 500 mg Tablet 60's

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Samtica 500 mg Tablet 60's may include fast or irregular heartbeat, lightheadedness, dizziness, or fainting, shortness of breath or difficulty breathing, swelling of the feet, ankles, or lower legs, and unexplained weight gain. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

Do not take Samtica 500 mg Tablet 60's if you are allergic to any of its components, if you have severe liver damage, or in combination with Ra-233 (used to treat prostate cancer). Inform your doctor if you have liver problems, high blood pressure, low blood potassium, heart failure, heart or blood vessel problems, irregular or rapid heartbeat, heart rhythm problems, shortness of breath, rapid weight gain, swelling in the legs, ankles, or feet, high blood sugar, bone problems, or if you have taken ketoconazole in the past for prostate cancer. Samtica 500 mg Tablet 60's may cause libido (decreased sex drive), muscle weakness, decreased red blood cells, and/or muscle pain. Samtica 500 mg Tablet 60's should not be given in combination with Ra-233 due to an increased risk of bone fracture or death.

Drug-Drug Interactions

verifiedApollotooltip
AbirateroneThioridazine
Critical
AbirateroneEliglustat
Critical

Drug-Drug Interactions

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AbirateroneThioridazine
Critical
How does the drug interact with Samtica 500 mg Tablet:
Taking Samtica 500 mg Tablet with Thioridazine can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Samtica 500 mg Tablet and Thioridazine together is not recommended and can result in an interaction; it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, or a rapid heartbeat. Do not discontinue any medications without consulting a doctor.
AbirateroneEliglustat
Critical
How does the drug interact with Samtica 500 mg Tablet:
Coadministration of Samtica 500 mg Tablet with Eliglustat can increase the levels of Eliglustat in the body. This increases the risk or severity of side effects.

How to manage the interaction:
Taking Samtica 500 mg Tablet with Eliglustat is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, slow heart rate, weak pulse, or heart palpitations. Do not discontinue any medications without consulting a doctor.
AbirateroneMesoridazine
Critical
How does the drug interact with Samtica 500 mg Tablet:
Taking Samtica 500 mg Tablet with Mesoridazine can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Samtica 500 mg Tablet and Mesoridazine together is not recommended as it can result in an interaction. It can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat. Do not discontinue any medications without consulting a doctor.
AbirateroneZiprasidone
Critical
How does the drug interact with Samtica 500 mg Tablet:
Taking Samtica 500 mg Tablet with ziprasidone can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Although there is an interaction between Samtica 500 mg Tablet and ziprasidone, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not discontinue any medications without consulting a doctor.
AbirateroneSaquinavir
Critical
How does the drug interact with Samtica 500 mg Tablet:
Taking Samtica 500 mg Tablet with Saquinavir can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Samtica 500 mg Tablet and Saquinavir together is not recommended as it can result in an interaction; it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
AbirateroneMethadone
Severe
How does the drug interact with Samtica 500 mg Tablet:
Taking Samtica 500 mg Tablet with Methadone can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Samtica 500 mg Tablet and Methadone together can result in an interaction; it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat Do not discontinue any medications without consulting a doctor.
AbirateroneEdoxaban
Severe
How does the drug interact with Samtica 500 mg Tablet:
Coadministration of Samtica 500 mg Tablet with Edoxaban can increase the levels of Edoxaban in the body. This increases the risk or severity of side effects like serious bleeding complications.

How to manage the interaction:
Taking Samtica 500 mg Tablet with Edoxaban together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience dizziness; lightheadedness; red or black, tarry stools; coughing up or vomiting blood that looks like coffee grounds; severe headache; and weakness, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AbirateroneCarbamazepine
Severe
How does the drug interact with Samtica 500 mg Tablet:
Taking carbamazepine and Samtica 500 mg Tablet together may reduce the blood level of Samtica 500 mg Tablet.

How to manage the interaction:
Taking carbamazepine and Samtica 500 mg Tablet together can result in an interaction, it can be taken if your doctor has advised it. Without consulting a doctor, never stop taking any medication.
AbirateroneTamoxifen
Severe
How does the drug interact with Samtica 500 mg Tablet:
Taking tamoxifen with Samtica 500 mg Tablet may reduce the effectiveness of tamoxifen and increase the risk of side effects.

How to manage the interaction:
Although taking tamoxifen and Samtica 500 mg Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience any unusual symptoms consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
AbirateroneDroperidol
Severe
How does the drug interact with Samtica 500 mg Tablet:
Using Droperidol together with Samtica 500 mg Tablet can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Samtica 500 mg Tablet and Droperidol together can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms, it's important to contact a doctor right away: an irregular heart rhythm, a heart condition, problems with your heart's electrical system, severe or long-lasting diarrhea or vomiting, complications, sudden dizziness or lightheadedness, fainting, difficulty breathing, heart palpitations, weakness, feeling sleepy or confused, muscle pain, or feeling nauseous or vomiting. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Avoid fast, fried, processed meats, refined carbs, and added sugar.
  • Get optimal sleep; rest well.

Habit Forming

No

Therapeutic Class

MISCELLANEOUS

Samtica 500 mg Tablet 60's Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Consult your doctor

It is unknown if alcohol affects Samtica 500 mg Tablet 60's. Please consult your doctor.

bannner image

Pregnancy

Unsafe

Samtica 500 mg Tablet 60's is not for use in women.

bannner image

Breast Feeding

Not applicable

Samtica 500 mg Tablet 60's is not for use in women.

bannner image

Driving

Safe if prescribed

Samtica 500 mg Tablet 60's is not likely to affect your ability to drive or operate machinery.

bannner image

Liver

Caution

Do not take Samtica 500 mg Tablet 60's if you have severe liver damage. Please consult your doctor if you have a liver impairment or any concerns.

bannner image

Kidney

Consult your doctor

Please consult your doctor if you have kidney impairment or any concerns.

bannner image

Children

Not applicable

Samtica 500 mg Tablet 60's is not for use in children and adolescents.

Have a query?

FAQs

Samtica 500 mg Tablet 60's is used to treat Prostate cancer.

Samtica 500 mg Tablet 60's works by stopping the body from making testosterone, thereby slowing the growth of prostate cancer.

Prednisolone/prednisone is prescribed along with Samtica 500 mg Tablet 60's to lower the chances of getting high blood pressure, fluid retention (having too much water in the body), or low blood potassium levels.

Samtica 500 mg Tablet 60's should not be given along with Ra-233 (a radioactive isotope used to treat prostate cancer) due to the increased risk of bone fracture or death. If you are prescribed to take Ra-233 following treatment with Samtica 500 mg Tablet 60's and prednisolone/prednisone, you must wait five days before starting treatment with Ra-233.

No, Samtica 500 mg Tablet 60's cannot cure prostate cancer. However, it is used to manage advanced or metastatic prostate cancer that works by inhibiting the production of testosterone, thereby preventing the growth and spread of cancer.

No, Samtica 500 mg Tablet 60's is not a chemotherapy drug. It is a hormone therapy medication, which reduces testosterone levels to help manage prostate cancer.

Yes, Samtica 500 mg Tablet 60's may affect the liver. Therefore, the doctor may advise regular blood tests to monitor its effects on the liver.

For patients taking Samtica 500 mg Tablet 60's liver investigations are recommended. However, the frequency may differ for each individual and can be determined by the doctor based on your medical condition.

Samtica 500 mg Tablet 60's can be taken orally on an empty stomach, either 1 hour before a meal or 2 hours after the meal. Swallow it as a whole with a glass of water. Do not chew or break it.

The side effects of Samtica 500 mg Tablet 60's include oedema, urinary tract infection, high blood pressure, low blood potassium, and diarrhoea. Consult the doctor if any of these symptoms persist or worsen.

Country of origin

India

Manufacturer/Marketer address

Samarth House, 168, Bangur Nagar, Off Link Road, Near Ayappa Temple & Kallol Kali Temple, Goregaon (W), Mumbai - 400 090.
Other Info - SAM0236

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 9:23 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.medicines.org.uk/emc/files/pil.2381.pdf
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/202379lbl.pdf
  3. https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=4e338e89-3cf2-48eb-b6e2-a06c608c6513
  4. https://medlineplus.gov/druginfo/meds/a611046.html

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