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Drug-Drug Interactions
AmlodipineDantrolene
Critical
Critical
Drug-Drug Interactions
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AmlodipineDantrolene
Critical
How does the drug interact with Triplixam 4mg/1.25mg/5mg Tablet:
Using Triplixam 4mg/1.25mg/5mg Tablet together with dantrolene may increase the risk of hyperkalemia (high blood potassium).
How to manage the interaction:
Taking Triplixam 4mg/1.25mg/5mg Tablet with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
Using Triplixam 4mg/1.25mg/5mg Tablet together with dantrolene may increase the risk of hyperkalemia (high blood potassium).
How to manage the interaction:
Taking Triplixam 4mg/1.25mg/5mg Tablet with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
Critical
How does the drug interact with Triplixam 4mg/1.25mg/5mg Tablet:
Combining Aliskiren with Triplixam 4mg/1.25mg/5mg Tablet can increase the risk of low blood pressure, high potassium levels, and kidney damage.
How to manage the interaction:
Taking Triplixam 4mg/1.25mg/5mg Tablet with Aliskiren is not recommended, but can be taken if prescribed by a doctor. However, if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Combining Aliskiren with Triplixam 4mg/1.25mg/5mg Tablet can increase the risk of low blood pressure, high potassium levels, and kidney damage.
How to manage the interaction:
Taking Triplixam 4mg/1.25mg/5mg Tablet with Aliskiren is not recommended, but can be taken if prescribed by a doctor. However, if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
IndapamideDroperidol
Critical
How does the drug interact with Triplixam 4mg/1.25mg/5mg Tablet:
Taking Droperidol with Triplixam 4mg/1.25mg/5mg Tablet can lead to severe heart problems.
How to manage the interaction:
Taking Droperidol with Triplixam 4mg/1.25mg/5mg Tablet is not recommended, but can be taken if prescribed by the doctor.
Taking Droperidol with Triplixam 4mg/1.25mg/5mg Tablet can lead to severe heart problems.
How to manage the interaction:
Taking Droperidol with Triplixam 4mg/1.25mg/5mg Tablet is not recommended, but can be taken if prescribed by the doctor.
IndapamideProtriptyline
Critical
How does the drug interact with Triplixam 4mg/1.25mg/5mg Tablet:
Taking Protriptyline along with Triplixam 4mg/1.25mg/5mg Tablet can lead to serious heart problems.
How to manage the interaction:
Taking Protriptyline with Triplixam 4mg/1.25mg/5mg Tablet is not recommended, but can be taken if prescribed by the doctor.
Taking Protriptyline along with Triplixam 4mg/1.25mg/5mg Tablet can lead to serious heart problems.
How to manage the interaction:
Taking Protriptyline with Triplixam 4mg/1.25mg/5mg Tablet is not recommended, but can be taken if prescribed by the doctor.
Critical
How does the drug interact with Triplixam 4mg/1.25mg/5mg Tablet:
Taking Triplixam 4mg/1.25mg/5mg Tablet with Thioridazine can increase the risk of heart problems.
How to manage the interaction:
Taking Thioridazine with Triplixam 4mg/1.25mg/5mg Tablet is not recommended, but can be taken if prescribed by the doctor.
Taking Triplixam 4mg/1.25mg/5mg Tablet with Thioridazine can increase the risk of heart problems.
How to manage the interaction:
Taking Thioridazine with Triplixam 4mg/1.25mg/5mg Tablet is not recommended, but can be taken if prescribed by the doctor.
Severe
How does the drug interact with Triplixam 4mg/1.25mg/5mg Tablet:
Co-administration of Tizanidine and Triplixam 4mg/1.25mg/5mg Tablet can increase the risk or severity of developing side effects like low blood pressure.
How to manage the interaction:
Although co-administration of Triplixam 4mg/1.25mg/5mg Tablet with tizanidine can result in an interaction, it can be taken when a doctor has advised it. However, if you experience headache, dizziness, palpitations, or irregular heart rate while taking these drugs, contact the doctor immediately. Use caution while getting up from a sitting or sleeping position and avoid driving or using dangerous machinery. Do not discontinue any medications without consulting the doctor.
Co-administration of Tizanidine and Triplixam 4mg/1.25mg/5mg Tablet can increase the risk or severity of developing side effects like low blood pressure.
How to manage the interaction:
Although co-administration of Triplixam 4mg/1.25mg/5mg Tablet with tizanidine can result in an interaction, it can be taken when a doctor has advised it. However, if you experience headache, dizziness, palpitations, or irregular heart rate while taking these drugs, contact the doctor immediately. Use caution while getting up from a sitting or sleeping position and avoid driving or using dangerous machinery. Do not discontinue any medications without consulting the doctor.
Severe
How does the drug interact with Triplixam 4mg/1.25mg/5mg Tablet:
Coadministration of lemborexant and Triplixam 4mg/1.25mg/5mg Tablet may increase the blood levels of lemborexant.
How to manage the interaction:
Although co-administration of Triplixam 4mg/1.25mg/5mg Tablet with Lemborexant can result in an interaction, it can be taken if a doctor has advised it. However, consult your doctor if you experience abnormal sleep patterns, worsening of depression, changes in heartbeat, or headache. Do not discontinue any medications without consulting a doctor.
Coadministration of lemborexant and Triplixam 4mg/1.25mg/5mg Tablet may increase the blood levels of lemborexant.
How to manage the interaction:
Although co-administration of Triplixam 4mg/1.25mg/5mg Tablet with Lemborexant can result in an interaction, it can be taken if a doctor has advised it. However, consult your doctor if you experience abnormal sleep patterns, worsening of depression, changes in heartbeat, or headache. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Triplixam 4mg/1.25mg/5mg Tablet:
Taking simvastatin with Triplixam 4mg/1.25mg/5mg Tablet may result in considerably higher blood levels of simvastatin and may increase the risk of side effects (liver damage and rhabdomyolysis - an uncommon but serious illness characterized by the breakdown of skeletal muscle tissue).
How to manage the interaction:
Although taking Triplixam 4mg/1.25mg/5mg Tablet with simvastatin can result in an interaction, it can be taken if a doctor has advised it. If you have unexplained muscular pain, soreness, or weakness while using simvastatin, especially if these symptoms are accompanied by fever or dark-colored urine, consult the doctor immediately. However, if you develop a fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes, consult the doctor. Do not stop using any medications without a doctor's advice.
Taking simvastatin with Triplixam 4mg/1.25mg/5mg Tablet may result in considerably higher blood levels of simvastatin and may increase the risk of side effects (liver damage and rhabdomyolysis - an uncommon but serious illness characterized by the breakdown of skeletal muscle tissue).
How to manage the interaction:
Although taking Triplixam 4mg/1.25mg/5mg Tablet with simvastatin can result in an interaction, it can be taken if a doctor has advised it. If you have unexplained muscular pain, soreness, or weakness while using simvastatin, especially if these symptoms are accompanied by fever or dark-colored urine, consult the doctor immediately. However, if you develop a fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes, consult the doctor. Do not stop using any medications without a doctor's advice.
AmlodipineMitotane
Severe
How does the drug interact with Triplixam 4mg/1.25mg/5mg Tablet:
Using Triplixam 4mg/1.25mg/5mg Tablet and mitotane together may drastically lower Triplixam 4mg/1.25mg/5mg Tablet blood levels, which makes the medicine less effective.
How to manage the interaction:
Although co-administration of Triplixam 4mg/1.25mg/5mg Tablet with mitotane can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
Using Triplixam 4mg/1.25mg/5mg Tablet and mitotane together may drastically lower Triplixam 4mg/1.25mg/5mg Tablet blood levels, which makes the medicine less effective.
How to manage the interaction:
Although co-administration of Triplixam 4mg/1.25mg/5mg Tablet with mitotane can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipineDolasetron
Severe
How does the drug interact with Triplixam 4mg/1.25mg/5mg Tablet:
Using dolasetron together with Triplixam 4mg/1.25mg/5mg Tablet can increase the risk of an irregular heart rhythm that may be serious.
How to manage the interaction:
There may be a possibility of interaction between Triplixam 4mg/1.25mg/5mg Tablet and Dolasetron, but it can be taken if prescribed by a doctor. If you have any of these symptoms, like feeling dizzy, lightheaded, or your heart beating irregularly, it's important to call a doctor right away. Do not stop using any medications without a doctor's advice.
Using dolasetron together with Triplixam 4mg/1.25mg/5mg Tablet can increase the risk of an irregular heart rhythm that may be serious.
How to manage the interaction:
There may be a possibility of interaction between Triplixam 4mg/1.25mg/5mg Tablet and Dolasetron, but it can be taken if prescribed by a doctor. If you have any of these symptoms, like feeling dizzy, lightheaded, or your heart beating irregularly, it's important to call a doctor right away. Do not stop using any medications without a doctor's advice.
Drug-Food Interactions
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.
Drug-Food Interactions
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Alcohol
Caution
Avoid consuming alcohol as it might cause increased dizziness.
Pregnancy
Caution
Triplixam 4mg/1.25mg/5mg Tablet is not recommended during early pregnancy and should not be taken when more than 3 months pregnant as it may cause serious harm to the baby. Please consult your doctor if you are pregnant, think you are pregnant or planning for pregnancy.
Breast Feeding
Unsafe
Triplixam 4mg/1.25mg/5mg Tablet is not recommended for breastfeeding mothers. Talk to your doctor if you have any concerns.
Driving
Caution
Triplixam 4mg/1.25mg/5mg Tablet may cause dizziness, do not drive or operate heavy machinery if you feel dizzy.
Liver
Caution
Dose adjustment may be needed. Please consult your doctor if you have liver problems or any concerns regarding this. Avoid taking Triplixam 4mg/1.25mg/5mg Tablet if you have severe liver disease or hepatic encephalopathy.
Kidney
Caution
Dose adjustment may be needed. Avoid taking Triplixam 4mg/1.25mg/5mg Tablet if you have severe kidney problems. Please consult your doctor if you have kidney problems or any concerns regarding this.
Children
Unsafe
Triplixam 4mg/1.25mg/5mg Tablet is not recommended for children as safety and effectiveness have not been established.
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