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  3. ZYTIGA 250MG TABLET

ZYTIGA 250MG TABLET, Pack of 1 TABLET
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Composition :

ABIRATERONE ACETATE-250MG

Manufacturer/Marketer :

Johnson & Johnson Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About ZYTIGA 250MG TABLET

ZYTIGA 250MG TABLET is an anti-androgen medicine used in the treatment of prostate cancer. It is used to treat metastatic castration-resistant prostate cancer (a condition where cancer does not get controlled with hormonal therapy) and metastatic castration-sensitive prostate cancer (a condition where cancer has spread to other parts of the body but can be controlled) in men. Prostate cancer is a condition that occurs when the prostate gland cells increase abnormally. Symptoms may include difficulty in urinating, pain, numbness, etc.

ZYTIGA 250MG TABLET contains Abiraterone acetate, which belongs to the class of androgen biosynthesis inhibitors. Testosterone is a natural hormone produced by the body. This causes an increase in cancer cells in the prostate gland. ZYTIGA 250MG TABLET works by inhibiting the production of the testosterone hormone and thus stops the growth and spread of cancer. 

ZYTIGA 250MG TABLET may cause certain side effects such as nausea, dizziness, heartburn, headache, diarrhoea, muscle weakness, joint pain, confusion, hot flushes, loss of appetite and groin pain. These side effects usually disappear without any medical attention. However, if these side effects persist, inform your doctor. Take this medicine as advised by your doctor. It should be taken on an empty stomach at least 2 hours before or after meals. Your doctor will decide the dose of the medicine based on the severity of your disease.

ZYTIGA 250MG TABLET should be avoided if you are allergic to it. Inform your doctor if you have any pre-existing or a history of liver/kidney disease, cardiovascular disease, adrenocortical insufficiency, hypokalemia, hypoglycaemia, fluid retention before taking ZYTIGA 250MG TABLET. ZYTIGA 250MG TABLET is not recommended for use in women and children as the safety and efficacy of this medicine are not established. Inform your doctor of all your ongoing medications to avoid interactions. This medicine is used in combination with prednisolone for the treatment of prostate cancer. 

Uses of ZYTIGA 250MG TABLET

ZYTIGA 250MG TABLET is used to treat prostate cancer. The detailed uses of ZYTIGA 250MG TABLET are as follows:<br/>• Manages advanced prostate cancer: ZYTIGA 250MG TABLET is used in combination with prednisone to treat prostate cancer that has spread to other parts of the body.<br/>• Helps lower hormone levels: ZYTIGA 250MG TABLET reduces the production of certain hormones that fuel the growth of prostate cancer cells.<br/>

Directions for Use

• ZYTIGA 250MG TABLET can be taken on an empty stomach at least two hours before or after a meal as directed by the doctor.• Follow your doctor's instructions on the dosage and timing of this medication.• Swallow ZYTIGA 250MG TABLET as a whole with a glass of water.• Do not break, chew or crush ZYTIGA 250MG TABLET.

Medicinal Benefits

ZYTIGA 250MG TABLET contains Abiraterone acetate, which belongs to the class of androgen biosynthesis inhibitors. Testosterone is a natural hormone produced by the body. This causes increase of cancer cells in prostate gland. ZYTIGA 250MG TABLET works by inhibiting the production of the testosterone hormone and thus stops the growth and spread of cancer. ZYTIGA 250MG TABLET is used in combination with prednisolone for the treatment of prostate cancer. It is mainly intended for use in men only.

How ZYTIGA 250MG TABLET Works

ZYTIGA 250MG TABLET contains Abiraterone acetate, which belongs to the class of androgen biosynthesis inhibitors. Testosterone is a natural hormone produced by the body. This causes an increase in cancer cells in the prostate gland. ZYTIGA 250MG TABLET works by inhibiting the production of the testosterone hormone and thus stops the growth and spread of cancer.

Storage

Store in a cool and dry place away from sunlight
Side effects of Zytiga 250mg Tablet
  • If you have discomfort, illness, or unease after taking medication, seek medical attention.
  • Your treatment plan may be modified, including adjusting the dosage, substituting with an alternative medication, or discontinuing the medication. Additionally, certain lifestyle changes may be recommended to help manage symptoms.
  • To manage discomfort, follow your doctor's advice, like getting plenty of rest, or staying hydrated, and practising stress-reducing techniques.
  • Track your symptoms regularly and report any changes or concerns to your healthcare provider to manage the discomfort effectively.
  • Talk to your doctor about oral potassium supplements.
  • Eat potassium rich foods such as bananas, avocados, oranges, dark leafy greens, beans and peas, fish, spinach, milk and tomatoes.
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.

What if I have taken an overdose of ZYTIGA 250MG TABLET

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of ZYTIGA 250MG TABLET may include fast or irregular heartbeat, lightheadedness, dizziness, or fainting, shortness of breath or difficulty breathing, swelling of the feet, ankles, or lower legs, and unexplained weight gain. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

ZYTIGA 250MG TABLET should be avoided if you are allergic to it or any other components present in it. Inform your doctor if you have/had any conditions like liver/kidney disease, cardiovascular disease, adrenocortical insufficiency, hypokalemia, hypoglycaemia, fluid retention or taking any other medicines before taking ZYTIGA 250MG TABLET as it may cause serious side effects. ZYTIGA 250MG TABLET is not recommended for use in women and children as the safety and efficacy of this medicine are not established. This medicine is used in combination with prednisolone for the treatment of prostate cancer.

Drug-Drug Interactions

verifiedApollotooltip
AbirateroneEliglustat
Critical
AbirateroneMesoridazine
Critical

Drug-Drug Interactions

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AbirateroneEliglustat
Critical
How does the drug interact with Zytiga 250mg Tablet:
Coadministration of Zytiga 250mg Tablet with Eliglustat can increase the levels of Eliglustat in the body. This increases the risk or severity of side effects.

How to manage the interaction:
Taking Zytiga 250mg Tablet with Eliglustat is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, slow heart rate, weak pulse, or heart palpitations. Do not discontinue any medications without consulting a doctor.
AbirateroneMesoridazine
Critical
How does the drug interact with Zytiga 250mg Tablet:
Taking Zytiga 250mg Tablet with Mesoridazine can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Zytiga 250mg Tablet and Mesoridazine together is not recommended as it can result in an interaction. It can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat. Do not discontinue any medications without consulting a doctor.
AbirateroneZiprasidone
Critical
How does the drug interact with Zytiga 250mg Tablet:
Taking Zytiga 250mg Tablet with ziprasidone can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Although there is an interaction between Zytiga 250mg Tablet and ziprasidone, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not discontinue any medications without consulting a doctor.
AbirateroneThioridazine
Critical
How does the drug interact with Zytiga 250mg Tablet:
Taking Zytiga 250mg Tablet with Thioridazine can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Zytiga 250mg Tablet and Thioridazine together is not recommended and can result in an interaction; it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, or a rapid heartbeat. Do not discontinue any medications without consulting a doctor.
AbirateroneSaquinavir
Critical
How does the drug interact with Zytiga 250mg Tablet:
Taking Zytiga 250mg Tablet with Saquinavir can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Zytiga 250mg Tablet and Saquinavir together is not recommended as it can result in an interaction; it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
AbirateroneGatifloxacin
Severe
How does the drug interact with Zytiga 250mg Tablet:
Taking Zytiga 250mg Tablet with Gatifloxacin can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Zytiga 250mg Tablet with Gatifloxacin together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AbirateroneSparfloxacin
Severe
How does the drug interact with Zytiga 250mg Tablet:
Taking Zytiga 250mg Tablet with Sparfloxacin can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Zytiga 250mg Tablet and Sparfloxacin together can result in an interaction; it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, or a rapid heartbeat. Do not discontinue any medications without consulting a doctor.
AbirateroneHydrocodone
Severe
How does the drug interact with Zytiga 250mg Tablet:
Coadministration of Zytiga 250mg Tablet with Hydrocodone can increase the levels of Hydrocodone in the body. This increases the risk or severity of side effects like low blood pressure, and low respiratory rate.

How to manage the interaction:
Taking Zytiga 250mg Tablet with Hydrocodone together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience drowsiness, dizziness, lightheadedness, difficulty concentrating, impairment in thinking and judgment, fainting, confusion, excessive drowsiness, slow heart rate, and shallow or difficult breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AbirateroneTamoxifen
Severe
How does the drug interact with Zytiga 250mg Tablet:
Taking tamoxifen with Zytiga 250mg Tablet may reduce the effectiveness of tamoxifen and increase the risk of side effects.

How to manage the interaction:
Although taking tamoxifen and Zytiga 250mg Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience any unusual symptoms consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
AbirateronePasireotide
Severe
How does the drug interact with Zytiga 250mg Tablet:
Taking Zytiga 250mg Tablet with Pasireotide can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Zytiga 250mg Tablet with Pasireotide together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Try to take vegetables like cauliflower, cabbage, broccoli, spinach and kale. This food slows the growth of prostate cancer and even reduces the risk of prostate cancer.
  • It is advised to consume fewer dairy products as these foods may increase the risk of prostate cancer. 
  • Physical activity helps in strengthening muscles, reduces fatigue, helps in weight loss and gives strength.
  • Maintain a healthy weight by doing regular simple exercises and yoga. 
  • Getting adequate sleep as resting helps improve your health and mental ability and improves attention. 
  • Avoid including red meat high amounts of meat in your diet. When meat is cooked, it may increase the risk of developing prostate cancer.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

ZYTIGA 250MG TABLET Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

Interaction of ZYTIGA 250MG TABLET with alcohol is unknown. It is advisable to consult your doctor if you have concerns.

bannner image

Pregnancy

Not applicable

Not intended for women.

bannner image

Breast Feeding

Not applicable

Not intended for women.

bannner image

Driving

Caution

ZYTIGA 250MG TABLET may decrease alertness or make you feel sleepy and dizzy. So, do not drive or operate heavy machinery while taking ZYTIGA 250MG TABLET until your vision improves.

bannner image

Liver

Caution

ZYTIGA 250MG TABLET should be used with caution, especially if you have a history of liver diseases/conditions. Your doctor may adjust the dose based on your condition.

bannner image

Kidney

Caution

ZYTIGA 250MG TABLET should be used with caution, especially if you have a history of kidney diseases/conditions. Your doctor may adjust the dose based on your condition.

bannner image

Children

Unsafe

ZYTIGA 250MG TABLET is not recommended for use in children as the safety and efficacy of this medicine are not established.

Have a query?

FAQs

ZYTIGA 250MG TABLET is used to treat Prostate Cancer.

ZYTIGA 250MG TABLET contains Abiraterone acetate, which belongs to the class of androgen biosynthesis inhibitors. It works by inhibiting the production of the testosterone hormone and thus stops the growth and spread of cancer.

No, do not stop taking ZYTIGA 250MG TABLET without consulting your doctor. It is recommended to take this medicine for the entire prescribed duration, even when symptoms improve or resolve.

The common side-effects of ZYTIGA 250MG TABLET are nausea, dizziness, heartburn, headache, diarrhoea, muscle weakness, joint pain, confusion, hot flushes, loss of appetite, and groin pain. These side effects usually do not require any medical attention.

Take ZYTIGA 250MG TABLET as advised by your doctor. However, if you forget or miss any dose of ZYTIGA 250MG TABLET, take it as soon as you remember unless it is time for your next dose. But do not double the dose.

Inform your doctor if you have a pre-existing or a history of liver/kidney disease, hypoglycemia, hypokalemia, bone disorders, adrenocortical insufficiency, fluid retention and cardiovascular conditions before taking ZYTIGA 250MG TABLET.

ZYTIGA 250MG TABLET is not a cure for prostate cancer. However, it helps manage advanced stages by blocking testosterone production, thereby slowing the growth and progression of the cancer.

No, ZYTIGA 250MG TABLET is not a chemotherapy drug. ZYTIGA 250MG TABLET is a hormonal therapy that lowers testosterone levels to reduce the growth of prostate cancer.

You need to take prednisolone with ZYTIGA 250MG TABLET to reduce the risk of high blood pressure, fluid retention (too much water in your body), and low potassium levels in your blood which may be caused by ZYTIGA 250MG TABLET.

Yes, ZYTIGA 250MG TABLET can affect the liver. Your healthcare provider will perform blood tests to check your liver function before and during treatment.

Liver function tests (investigation) should be conducted before starting ZYTIGA 250MG TABLET and periodically during treatment, as advised by your healthcare provider.

ZYTIGA 250MG TABLET should be taken once daily on an empty stomach, at least two hours after eating or one hour before eating. Swallow ZYTIGA 250MG TABLET whole with a glass of water; do not chew, crush, or break it. Always follow the recommended dose.

Country of origin

INDIA

Manufacturer/Marketer address

Corporate Communications, Johnson & Johnson Private Limited., 501 Arena Space, Behind Majas Bus Depot, Off Jogeshwari Vikhroli Link Road, Jogeshwari (E), Mumbai 400 060
Other Info - ZYT0040

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Author Details

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 7:04 AM IST

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Reference

  1. https://www.sterisindia.com/latest-update/abiraterone-acetate-/2822
  2. https://lotusinternational.com/product/zytiga/
  3. https://www.zytiga.com/
  4. https://medlineplus.gov/druginfo/meds/a611046.html
  5. https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/202379s031s033lbl.pdf

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