Chronic, worsening left-sided headaches during sleep or early mornings can point to conditions like migraines, cluster headaches, or sleep-related headache disorders. Because these conditions have different triggers, there is no single medication that provides a permanent cure without a precise diagnosis. Relying solely on pain relievers can actually worsen your symptoms through medication overuse. To find a lasting solution, you should consult a neurologist. They can prescribe daily preventive medications (such as amitriptyline, topiramate, or beta-blockers) to reduce headache frequency and severity, while safely addressing your nervousness and sleeplessness. Please avoid self-medicating.