MYOGREL AP 150MG TABLET

Manufacturer : MAC-MACLEODS PHARMACEUTICALS
Composition : ASPIRIN-150MG+CLOPIDOGREL-75MG
Dose Form : TABLET
Description : MYOGREL AP150 TAB
Route Of Administration : ORAL
Pack : 6
Out of stock
SKU
MYO0010
₹19.60
Manufacturer : MAC-MACLEODS PHARMACEUTICALS
Composition : ASPIRIN-150MG+CLOPIDOGREL-75MG
Dose Form : TABLET
Description : MYOGREL AP150 TAB
Route Of Administration : ORAL
Pack : 6

Drug Ingredient Information

ASPIRIN-150MG+CLOPIDOGREL-75MG

ASPIRIN

Information for patients
Drug Information Aspirin belong to a group of medicines which have analgesic (pain relieving), anti-inflammatory (inflammation reducing) and antipyretic (temperature reducing) properties. These may be used for the relief of: •headache, toothache, migraine, neuralgia (nerve pain), sore throat or period pains. •symptoms of influenza, feverishness, rheumatic pains, sciatica (nerve pain of the leg/back), lumbago (lower back pain), fibrositis (muscular rheumatism), muscular aches and pains. The may also be used to prevent blood clots especially after a heart attack or in patients with unstable angina or reduced blood flow in the brain.
Drug Alert
Alert Do not take Aspirin and tell your doctor if you have: •an allergy (hypersensitivity) to aspirin, salicylates or non-steroidal anti-inflammatory drugs (NSAIDs) or other ingredients in the product. You may have developed difficulty breathing, a runny nose, itchy skin or swelling after taking aspirin or a NSAID previously •a stomach ulcer or a history of ulcers or indigestion •nasal polyps associated with asthma •haemophilia or other blood clotting disorder or are taking medicines to thin the blood •severe liver, kidney or heart failure •are in the third trimester of pregnacy •the patient is a child under 16 years old.
Before Consuming the Medicine
Avoid Drug Do not take Aspirin and tell your doctor if you have: •an allergy (hypersensitivity) to aspirin, salicylates or non-steroidal anti-inflammatory drugs (NSAIDs) or other ingredients in the product. You may have developed difficulty breathing, a runny nose, itchy skin or swelling after taking aspirin or a NSAID previously •a stomach ulcer or a history of ulcers or indigestion •nasal polyps associated with asthma •haemophilia or other blood clotting disorder or are taking medicines to thin the blood •severe liver, kidney or heart failure •are in the third trimester of pregnacy •the patient is a child under 16 years old.
Drug Special Care •asthma or allergies •heart, liver or kidney problems or gout •an overactive thyroid gland •dehydration •anaemia or suffer from a deficiency of the enzyme glucose-6-phosphate dehydrogenase (G6PD) this can cause episodes of anaemia after eating certain foods such as fava beans (favism) •systemic lupus erythematosus (SLE) or other connective tissue disease •elderly •had any disorders affecting blood vessels in the brain •received a varicella (chickenpox) vaccination within the last 6 weeks •planning to become pregnant.
Drug Drug Interactions Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription. Especially: •medicines to prevent blood clotting such as warfarin, dipyridamole and heparin •metoclopramide or domperidone (to prevent sickness) •diuretics (“water ”) e.g. spironolactone, frusemide, acetazolamide (to treat high blood pressure) •medicines which make your urine more alkaline such as antacids, citrates •probenecid, sulphinpyrazone (to treat gout) •methotrexate (to treat some cancers, psoriasis and rheumatic disease) •antidiabetics •phenytoin or sodium valproate (to treat epilepsy) •corticosteroids (to suppress the immune system) •mifepristone (to induce abortion) •other non-steroidal anti-inflammatory drugs - NSAIDs (eg ibuprofen or naproxen) •medicines which can cause hearing problems (vancomycin) •medicines to treat high blood pressure (ACE inhibitors, Calcium channel blockers) •medicines to treat depression (SSRIs) •varicella (chickenpox) vaccine. Aspirin should be avoid for 6 weeks after vaccination •herbal medicines containing ginkgo biloba
Drug Pregnancy Interaction Avoid taking Aspirin during pregnancy especially in the last 3 months of pregnancy or whilst breast-feeding. Ask your doctor or pharmacist for advice before taking this medicine.
Drug Breast feeding Interaction Avoid taking Aspirin during pregnancy especially in the last 3 months of pregnancy or whilst breast-feeding. Ask your doctor or pharmacist for advice before taking this medicine.
Drug Machinery Interaction
Drug More Information There is a possible association between aspirin and Reye’s Syndrome when given to children. Reye’s syndrome is a very rare disease, which can be fatal. For this reason aspirin should not be given to children aged under 16 years, unless on the advice of a doctor.
How to take the Medicine
Consumption Info If you need to have an operation including having your teeth removed or blood and urine tests, tell your doctor or dentist you are taking this medicine.
Drug quanitty Adults, including the elderly: 1 or 2 every 3 to 4 hours as required. No more than 12 in any 24 hour period. Children under 16 years old: Not recommended. For prevention of blood clots: 1 once a day
Drug Dose Always take Aspirin exactly as your doctor has told you. If you are not sure, check with your doctor or pharmacist. Avoid alcohol whilst taking this medicine. Swallow the with a glass of water.
Excess Drug Consumption If you (or someone else) swallow a lot of at the same time, or you think a child may have swallowed any contact your nearest hospital casualty department or tell your doctor immediately. Symptoms of an overdose include ringing in the ears, spinning sensation, fast breathing rate, changes in some of the chemicals in the body, heart or kidney failure, fever or coma.
Forgot Drug Consumption Do not take a double dose to make up for a forgotten dose. If you forget to take a dose take it as soon as you remember it and then take the next dose at the right time. Do not take more than one dose in any 4 hour period.
Stop Drug Consumption
Possible Side Effects
General Information
Common Drug Side Effects Allergic reactions - runny nose, itchy, red, blotchy, blistered skin, swelling of the face, lips, throat or tongue, difficulty breathing, worsening of asthma. Gastrointestinal system - stomach ulcers or bleeding which can be severe (you may develop bloody or black tarry stools, severe stomach pain and vomit blood), stomach irritation (mild stomach pain, heartburn and feeling or being sick) and inflammation of the liver. Deaths have occurred. Blood - anaemia, changes in numbers and types of blood cells and enzymes seen in blood tests. If you have an increase in number of nose bleeds, longer bleeding time or notice that you bruise more easily or have more infections talk to your doctor. Kidney - changes in the amount or need to urinate. Ears - ringing or buzzing in the ear. Salicylism - if you take large doses for a long time you may develop symptoms of salicylism, these include: dizziness, ringing or buzzing in the ear, deafness, sweating, feeling or being sick, headache and confusion.
Rare Drug Side Effects
Very Rare Drug Side Effects
Drug Side Effects Symptoms
How to Store the Medicine
How to Store the Medicine Keep out of the reach and sight of children. Store the below 25°C in a dry place. Do not use Aspirin after the expiry date stated on the label/carton/bottle. The expiry date refers to the last day of that month. Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.

CLOPIDOGREL

Information for patients
Drug Information Clopidogrel belongs to a group of medicines called antiplatelet medicinal products. Platelets are very small structures in the blood, smaller than red or white blood cells, which clump together during blood clotting. By preventing this clumping, antiplatelet medicinal products reduce the chances of blood clots forming (a process called thrombosis). Clopidogrel is taken to prevent blood clots (thrombi) forming in hardened blood vessels (arteries), a process known as atherothrombosis, which can lead to atherothrombotic events (such as stroke, heart attack, or death). You have been prescribed Clopidogrel to help prevent blood clots and reduce the risk of these severe events because: -You have a condition of hardening of arteries (also known as atherosclerosis), and -You have previously experienced a heart attack, stroke or have a condition known as peripheral arterial disease, or -You have experienced a severe type of chest pain known as ‘unstable angina’ or ‘myocardial infarction’ (heart attack). For the treatment of this condition your doctor may have placed a stent in the blocked or narrowed artery to restore effective blood flow. You should also be given acetylsalicylic acid (a substance present in many medicines used to relieve pain and lower fever as well as to prevent blood clotting) by your doctor.
Drug Alert
Alert •If you are allergic (hypersensitive) to clopidogrel •If you have a medical condition that is currently causing bleeding such as a stomach ulcer or bleeding within the brain; •If you suffer from severe liver disease. If you think any of these apply to you, or if you are in any doubt at all, consult your doctor before taking Clopidogrel.
Before Consuming the Medicine
Avoid Drug •If you are allergic (hypersensitive) to clopidogrel •If you have a medical condition that is currently causing bleeding such as a stomach ulcer or bleeding within the brain; •If you suffer from severe liver disease. If you think any of these apply to you, or if you are in any doubt at all, consult your doctor before taking Clopidogrel.
Drug Special Care If any of the situations mentioned below apply to you, you should tell your doctor before taking Clopidogrel: •if you have a risk of bleeding such as -a medical condition that puts you at risk of internal bleeding (such as a stomach ulcer) -a blood disorder that makes you prone to internal bleeding (bleeding inside any tissues, organs or joints of your body). -a recent serious injury -a recent surgery (including dental) -a planned surgery (including dental) in the next seven days •if you have had a clot in an artery of your brain (ischaemic stroke) which occurred within the last seven days •if you have kidney or liver disease While you are taking Clopidogrel: •You should tell your doctor if a surgery (including dental) is planned. •You should also tell your doctor immediately if you develop a medical condition (also known as Thrombotic Thrombocytopenic Purpura or TTP) that includes fever and bruising under the skin that may appear as red pinpoint dots, with or without unexplained extreme tiredness, confusion, yellowing of the skin or eyes (jaundice). •If you cut or injure yourself, it may take longer than usual for bleeding to stop. This is linked to the way your medicine works as it prevents the ability of blood clots to form. For minor cuts and injuries e.g., cutting yourself, shaving, this is usually of no concern. However, if you are concerned by your bleeding, you should contact your doctor straight away. •Your doctor may order blood tests. Clopidogrel is not intended for use in children or adolescents.
Drug Drug Interactions Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription. Some other medicines may influence the use of Clopidogrel or vice versa. You should specifically tell your doctor if you take -oral anticoagulants, medicines used to reduce blood clotting, -a non-steroidal anti-inflammatory medicine, usually used to treat painful and/or inflammatory conditions of muscle or joints, -heparin or any other medicine used to reduce blood clotting, -a proton pump inhibitor (e.g, omeprazole) for upset stomach, -fluconazole, voriconazole, ciprofloxacin, or chloramphenicol, medicines to treat bacterial and fungal infections, -cimetidine, medicine to treat upset stomach, -fluoxetine, fluvoxamine, or moclobemide, medicines to treat depression, -carbamazepine, or oxcarbazepine, medicines to treat some forms of epilepsy, -ticlopidine, other antiplatelet agent. If you have experienced severe chest pain (unstable angina or heart attack), you may be prescribed Clopidogrel in combination with acetylsalicylic acid, a substance present in many medicines used to relieve pain and lower fever. An occasional use of acetylsalicylic acid (no more than 1,000 mg in any 24 hour period) should generally not cause a problem, but prolonged use in other circumstances should be discussed with your doctor.
Drug Pregnancy Interaction It is preferable not to use this product during pregnancy and breast-feeding. If you are pregnant or suspect that you are pregnant, you should tell your doctor or your pharmacist before taking Clopidogrel. If you become pregnant while taking Clopidogrel, consult your doctor immediately as it is recommended not to take clopidogrel while you are pregnant. While taking Clopidogrel, consult your doctor about the breast-feeding of a baby. Ask your doctor or pharmacist for advice before taking any medicine.
Drug Breast feeding Interaction It is preferable not to use this product during pregnancy and breast-feeding. If you are pregnant or suspect that you are pregnant, you should tell your doctor or your pharmacist before taking Clopidogrel. If you become pregnant while taking Clopidogrel, consult your doctor immediately as it is recommended not to take clopidogrel while you are pregnant. While taking Clopidogrel, consult your doctor about the breast-feeding of a baby. Ask your doctor or pharmacist for advice before taking any medicine.
Drug Machinery Interaction Clopidogrel is unlikely to affect your ability to drive or to use machines.
Drug More Information Clopidogrel may be taken with or without food.
How to take the Medicine
Consumption Info
Drug quanitty Always take Clopidogrel exactly as your doctor has told you. You should check with your doctor or pharmacist if you are not sure. If you have experienced severe chest pain (unstable angina or heart attack), your doctor may give you 300 mg of Clopidogrel (1 tablet of 300 mg or 4 tablets of 75 mg) once at the start of treatment. Then, the usual dose is one 75-mg tablet of Clopidogrel per day to be taken orally with or without food, and at the same time each day. You should take Clopidogrel for as long as your doctor continues to prescribe it.
Drug Dose
Excess Drug Consumption Contact your doctor or the nearest hospital emergency department because of the increased risk of bleeding.
Forgot Drug Consumption If you forget to take a dose of Clopidogrel, but remember within 12 hours of your usual time, take your tablet straightaway and then take your next tablet at the usual time.If you forget for more than 12 hours, simply take the next single dose at the usual time. Do not take a double dose to make up for the forgotten individual doses. For the 7, 14, 28 and 84 tablets pack sizes, you can check the day on which you last took a tablet of Clopidogrel by referring to the calendar printed on the blister.
Stop Drug Consumption Do not stop the treatment. Contact your doctor or pharmacist before stopping. If you have any further questions on the use of this product, ask your doctor or pharmacist.
Possible Side Effects
General Information Bleeding may occur as bleeding in the stomach or bowels, bruising, haematoma (unusual bleeding or bruising under the skin), nose bleed, blood in the urine. In a small number of cases, bleeding in the eye, inside the head, the lung or the joints has also been reported.
Common Drug Side Effects Diarrhoea, abdominal pain, indigestion or heartburn.
Rare Drug Side Effects Headache, stomach ulcer, vomiting, nausea, constipation, excessive gas in stomach or intestines, rashes, itching, dizziness, sensation of tingling and numbness.Vertigo.
Very Rare Drug Side Effects Jaundice; severe abdominal pain with or without back pain; fever, breathing difficulties sometimes associated with cough; generalised allergic reactions; swelling in the mouth; blisters of the skin; skin allergy; inflammation of the mouth (stomatitis); decrease in blood pressure; confusion; hallucinations; joint pain; muscular pain; changes in the way things taste.In addition, your doctor may identify changes in your blood or urine test results.
Drug Side Effects Symptoms If you cut or injure yourself, it may take longer than usual for bleeding to stop. This is linked to the way your medicine works as it prevents the ability of blood clots to form. For minor cuts and injuries e.g., cutting yourself, shaving, this is usually of no concern. However, if you are concerned by your bleeding, you should contact your doctor straightaway.-fever, signs of infection or extreme tiredness. These may be due to rare decrease of some blood cells. -signs of liver problems such as yellowing of the skin and/or the eyes (jaundice), whether or not associated with bleeding which appears under the skin as red pinpoint dots and/or confusion. -swelling in the mouth or skin disorders such as rashes and itching, blisters of the skin. These may be the signs of an allergic reaction.
How to Store the Medicine
How to Store the Medicine Keep out of the reach and sight of children.Do not use Clopidogrel after the expiry date which is stated on the carton and on the blister.Refer to the storage conditions on the carton. If Clopidogrel is supplied in PVC/PVDC/aluminium blisters, store below 30°C. If Clopidogrel is supplied in all aluminium blisters, it does not require any special storage conditions. Do not use Clopidogrel if you notice any visible sign of deterioration. Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.

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