Indapamide is used either alone or in combination with other medicines to treat high blood pressure (hypertension).
The active ingredient is indapamide hemihydrate, which is thought to work by relaxing some of the blood vessels in the body causing blood pressure to fall. The exact way in which it does this however, is not fully understood.
Ask your doctor if you have any questions about why this medicine has been prescribed for you. Your doctor may have prescribed it for another reason.
There is not enough information to recommend the use of this medicine in children.
This medicine is available only with a doctor’s prescription.
There is no evidence that Indapamide is addictive.
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||Do not take Indapamide if you have:
• an allergy to any medicine containing indapamide hemihydrate or Sulfonamide or sulfa (sulpha) medicines or any of the ingredients listed in the contents.
Some of the symptoms of an allergic reaction may include: shortness of breath; wheezing or difficulty breathing; swelling of the face, lips, tongue or other parts of the body; rash, itching or hives on the skin.
• Severe liver disease or kidney problems.
• Do not take this medicine if you are pregnant or plan to become pregnant.
• Do not take this medicine if you are breastfeeding or plan to breastfeed
• Do not take this medicine after the expiry date printed on the pack or if the packaging is torn or shows signs of tampering. If it has expired or is damaged, return it to your pharmacist for disposal.
If you are not sure whether you should start taking this medicine, talk to your doctor
|Drug Special Care
||Before you start to take it:
Tell your doctor if you have allergies to any other medicines, foods, preservatives or dyes.
Tell your doctor if you have or have had any of the following medical conditions:
• Systemic lupus erythematosus (SLE)
• Low blood pressure
• Kidney problems
• Liver problems.
Your doctor may want to take special care if you have any of these conditions.
If you have not told your doctor about any of the above, tell him/her before you start taking Indapamide.
Things you must do
If you are about to be started on any new medicine, remind your doctor and pharmacist that you are taking Indapamide.
Tell any other doctors, dentists, and pharmacists who treat you that you are taking this medicine.
If you become pregnant while taking this medicine, tell your doctor immediately.
If you are about to have any blood tests, tell your doctor that you are taking this medicine. It may interfere with the results of some tests.
Keep all of your doctor’s appointments so that your progress can be checked. Your doctor may want to check your blood pressure, kidney function, sodium levels and potassium levels from time to time to make sure the medicine is working and to prevent unwanted side effects.
Things you must not do
Do not take Indapamide to treat any other complaints unless your doctor tells you to.
Do not give your medicine to anyone else, even if they have the same condition as you.
Things to be careful of
Be careful when drinking alcohol while you are taking this medicine. Dizziness or light-headedness may be worse if you drink alcohol, take strong pain killers, barbiturates or other medicines for high blood pressure while being treated with Indapamide.
If you feel light-headed, dizzy or faint when getting out of bed or standing up, get up slowly. Standing up slowly, especially when you get up from bed or chairs, will help your body get used to the change in position and blood pressure. If this problem continues or gets worse, talk to your doctor.
Make sure you drink enough water in hot weather and during exercise when you are taking Indapamide, especially if you sweat a lot.
Also make sure you tell your doctor if you become sick and have severe or continuing vomiting or diarrhoea while taking Indapamide. The loss of additional water and certain salts such as potassium from the body may make you feel faint, light-headed, weak or sick.
|Drug Drug Interactions
||Tell your doctor or pharmacist if you are taking any other medicines, including any that you get without a prescription from your pharmacy, supermarket or health food shop. Some medicines and Indapamide may interfere with each other. These include:
• Lithium, a medicine used to treat mood swings and some types of depression
• Other medicines used to treat high blood pressure
• Diuretics, also known as water or fluid tablets
• Barbiturates, medicines used to treat epilepsy, produce calmness or to help you sleep
• Corticosteroids, medicines used in the treatment of conditions such as allergic reactions, asthma, inflammatory and ''auto-immune'' diseases
• Strong pain killers.
These medicines may be affected by Indapamide or may affect how well it works. You may need different amounts of your medicines, or you may need to take different medicines.
Your doctor and pharmacist have more information on medicines to be careful with or avoid while taking this medicine.
|Drug Pregnancy Interaction
||There is no information on the use of Indapamide in pregnancy, therefore, Indapamide is not recommended for use in pregnant women.
|Drug Breast feeding Interaction
||Indapamide is not recommended for use in breastfeeding women, as it is not known whether this medicine passes into breast milk and how it may affect your baby.
|Drug Machinery Interaction
||Be careful driving or operating machinery until you know how Indapamide affects you. This medicine may cause tiredness, dizziness and light-headedness in some people. If you have any of these symptoms, do not drive, operate machinery or do anything else that could be dangerous.
|Drug More Information
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|How to take the
||Follow all directions given to you by your doctor or pharmacist carefully. They may differ from the information contained in this leaflet. If you do not understand the instructions on the box, ask your doctor or pharmacist for help.
||The usual adult dose is one tablet daily, taken in the morning.
||How to take it
Swallow the tablets whole with a full glass of water. Do not halve the tablets.
When to take it
Take your medicine at about the same time each morning. Taking it at the same time each morning will have the best effect. It will also help you remember when to take it.
It does not matter if you take this medicine before or after food.
How long to take it
Continue taking your medicine for as long as your doctor tells you. This medicine helps to control your condition, but does not cure it. It is important to keep taking your medicine even if you feel well.
|Excess Drug Consumption
||Immediately telephone your doctor or the National Poisons Information Centre for advice, or go to Accident and Emergency at the nearest hospital, if you think that you or anyone else may have taken too much Indapamide. Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention.
|Forgot Drug Consumption
||If it is almost time for your next dose, skip the dose you missed and take your next dose when you are meant to. Otherwise, take it as soon as you remember, and then go back to taking your medicine as you would normally. Do not take a double dose to make up for the dose that you missed.
If you are not sure what to do, ask your doctor or pharmacist.
If you have trouble remembering to take your medicine, ask your pharmacist for some hints.
|Stop Drug Consumption
||Do not stop taking your medicine or lower the dosage without checking with your doctor.
||Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking Indapamide. This medicine helps most people with high blood pressure, but it may have unwanted side effects in a few people. All medicines can have side effects. Sometimes they are serious, most of the time they are not. You may need medical attention if you get some of the side effects. Do not be alarmed by the following lists of side effects. You may not experience any of them.
Ask your doctor or pharmacist to answer any questions you may have.
|Common Drug Side Effects
||Tell your doctor or pharmacist if you notice any of the following and they worry you:
Loss of appetite
Unusual tiredness or weakness
Dizziness or lightheadedness, especially when getting up from a sitting or lying position
The above list includes the more common side effects of your medicine. They are usually mild and short-lived.
|Rare Drug Side Effects
||Tell your doctor immediately or go to Accident and Emergency at your nearest hospital if you notice any of the following:
• Fast or irregular heart beat
• Signs of a water or salt, e.g. potassium, imbalance in the body. Symptoms may include:
o Dryness of mouth
o Increased thirst
o Irregular heartbeat
o Weak pulse
o Muscle cramps or pain
o Nausea or vomiting
o Unusual tiredness or weakness
• Signs of an allergic reaction such as skin rash, itching or hives; swelling of the face, lips or tongue which may cause difficulty in swallowing or breathing; wheezing or shortness of breath.
The above list includes serious side effects. You may need urgent medical attention or hospitalisation.
|Very Rare Drug Side Effects
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|Drug Side Effects Symptoms
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|How to Store the
|How to Store the Medicine
Keep your tablets in the pack until it is time to take them. If you take the tablets out of the pack they may not keep well.
Keep your tablets in a cool dry place where the temperature stays below 30 degree Celcius.
Do not store Indapamide or any other medicine in the bathroom or near a sink. Do not leave it on a window sill or in the car. Heat and dampness can destroy some medicines.
Keep it where children cannot reach it. A locked cupboard at least one-and-a half metres above the ground is a good place to store medicines.
If your doctor tells you to stop taking this medicine or the expiry date has passed, ask your pharmacist what to do with any medicine that is left over.