NEBIVEL H TABLET

Manufacturer : RHY-RHYTHM PHARMA INDIA PVT LT
Composition : NEBIVOLOL-5MG+HYDROCHLOROTHIAZIDE-12.5MG
Dose Form : TABLET
Description : NEBIVEL H TAB
Route Of Administration : ORAL
Pack : 10
Out of stock
SKU
NEB0165
₹91.00
Manufacturer : RHY-RHYTHM PHARMA INDIA PVT LT
Composition : NEBIVOLOL-5MG+HYDROCHLOROTHIAZIDE-12.5MG
Dose Form : TABLET
Description : NEBIVEL H TAB
Route Of Administration : ORAL
Pack : 10

Drug Ingredient Information

NEBIVOLOL-5MG+HYDROCHLOROTHIAZIDE-12.5MG

NEBIVOLOL

Information for patients
Drug Information Nebivolol contains nebivolol which is a selective beta blocker and it dilates blood vessels (vasodilator). It is used for the treatment of raised blood pressure (hypertension). Nebivolol is also used to treat chronic heart failure in patients aged 70 or over.
Drug Alert
Alert
Before Consuming the Medicine
Avoid Drug •if you are allergic (hypersensitive) to nebivolol or to any of the other ingredients of Nebivolol. •if you have low blood pressure (the systolic or “upper” pressure is less than 90 mmHg) •if you have poor circulation in the arms or legs •if you have a very slow heartbeat (less than 60 heart beats per minute before having started this medication) •if you have been diagnosed with conduction disorders in your heart (such as sick sinus syndrome or atrio-ventricular blockade) and you do not have a functioning pacemaker •if you have acute heart failure, or you are receiving treatment into a vein (by intravenous ‘drip’) to help your heart work •if you have difficulty in breathing or wheezing (or history of) •if you have a tumour of the adrenal gland called phaeochromocytoma •if you have severe liver disease or liver function impairment •if you have a metabolic acidosis (such as in diabetic patients when the blood sugar has risen too much and blood has become too acidic) •if you use either floctafenine or sultopride containing medications.
Drug Special Care -If you have or develop one of the following conditions: •heart failure (inability of heart to pump enough blood for body´s needs) •a mild (first degree) atrioventricular blockade in your heart •chest pain caused by cramping of the coronary arteries (called Prinzmetal´s angina or variant angina) •poor circulation in the arms or legs, e.g. Raynaud’s disease or syndrome, cramp-like pains on walking •prolonged breathing problems (or history of) •diabetes: Nebivolol has no effect on blood sugar, but it could mask the signs of a low sugar level (e.g. trembling, fast heartbeat). •overactive thyroid gland, as Nebivolol may mask the signs of an abnormally fast heart rate due to this condition •allergy, as the allergic reactions may become stronger and more medicines may be needed to treat them •a skin condition known as psoriasis, as Nebivolol\ may aggravate the symptoms •wear contact lenses, as Nebivolol may reduce lacrimation and make the eyes dryer. Use in children and adolescents below 18 years old is not recommended. In these cases, your doctor may need to adapt your treatment or check you more often. If you need to have an operation and need an anaesthetic, it is important that you tell the surgeon or dentist that you are taking this medicine. If you have kidney problems, do not take this medicine for heart failure and inform your doctor.
Drug Drug Interactions Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription, herbal remedies and strong vitamins and minerals. Always tell your doctor or pharmacist if you are using or receiving any of the following medicines in addition to Nebivolol: •diltiazem or verapamil (used for high blood pressure and other heart problems). During Nebivolol treatment, verapamil should not be injected into a vein •other medicinal products known as calcium channel blockers for high blood pressure or other heart problems such as amlodipine, felodipine, lacidipine, nifedipine, nicardipine, nimodipine, nitrendipine •other antihypertensive medications or organic nitrates to treat chest pain •clonidine, guanfacin, moxonidine, methyldopa, rilmenidine used for the treatment of high blood pressure •medicinal products for cardiac arrhythmias (irregular heartbeat) such as quinidine, hydroquinidine, amiodarone, cibenzoline, flecainide, disopyramide, lidocaine, mexiletine, propafenone •tricyclic antidepressants (for depression), phenothiazines (for psychoses), or barbiturates (for epilepsy) •medicinal products for diabetes mellitus (insulins and oral preparations) •digoxin or other so called digitalis glycosides (to treat heart failure) •anti-inflammatory analgesics (NSAIDs) for pain and inflammation- please note that small daily antithrombotic doses of acetylsalicylic acid (e.g., 50 or 100 mg) can be used safely with Nebivolol •medicinal products for asthma, blocked nose or certain eye disorders such as glaucoma (increased pressure in the eye) or dilation of the pupil •anaesthetics: always inform your anaesthetist that you are on Nebivolol before being anaesthetized •cimetidine (to treat excessive stomach acid)- you should take Nebivolol during a meal, and the antacid drug between meals •medicinal products affecting the metabolism of nebivolol namely terbinafine (for fungal or yeast infections), bupropion (to help in cessation of smoking), chloroquine (for malaria or rheumatoid arthritis), levomepromazine (for psychoses), paroxetine, fluoxetine, thioridiazine (for depression) •amifostine (a protecting substance during chemo- or radiation therapy) •baclofen (a muscle relaxant) •mefloquine (an antimalarial).
Drug Pregnancy Interaction Nebivolol should not be used during pregnancy unless instructed to do so by a doctor.
Drug Breast feeding Interaction Breast-feeding is not recommended during administration of Nebivolol.
Drug Machinery Interaction No studies on the effects on the ability to drive and use machines have been performed. This medicine may cause dizziness or fainting as a result to reduction in blood pressure. If these occur, DO NOT drive or operate machinery. These effects are more likely to occur after initiation of the treatment or after dose increases.
Drug More Information Nebivolol 5 mg tablets can be taken before, during or after a meal, but also you can take them without food. The tablet or its parts should be swallowed with some water or another liquid.
How to take the Medicine
Consumption Info
Drug quanitty Treatment of raised blood pressure (hypertension) •The usual dose is 1 tablet per day. •Elderly patients and patients with a kidney disorder will usually start with 1/2 tablet daily. •It may take up to 4 weeks for this medicine to have full effect. Treatment of chronic heart failure •Your treatment will be started and monitored by an experienced physician. •Your doctor will start your treatment with 1/4 tablet per day. This may be increased after 1-2 weeks to 1/2 tablet per day, then to 1 tablet per day and then to 2 tablets per day until the correct dose is reached for you. •The maximum recommended dose is 10 mg (2 tablets a day). •You will need to be monitored for 2 hours by an experienced physician when you start treatment and every time your dose is increased. •Your doctor may reduce your dose if necessary, and you should not stop abruptly as this can worsen heart failure. •Patients with serious kidney problems should not take this medicine.
Drug Dose Always take Nebivolol exactly as your doctor has told you. You should check with your doctor or pharmacist if you are not sure.Take your medicine once daily, preferably at about the same time of day. Your doctor may decide to combine your tablets with other medicine for your condition. Nebivolol is not recommended in children and adolescents.
Excess Drug Consumption If you accidentally take too many tablets (overdose), you may experience slow heart beat, low blood pressure or other heart problems, or difficulty in breathing or wheezing. Contact your nearest hospital casualty department or tell your doctor or pharmacist immediately.
Forgot Drug Consumption If you forget to take your medicine, but remember to take it after a short time, take the next tablet normally, when it is the time to take it. However, if a long delay has occurred (e.g. all day) skip that dose and take the next dose the next day at the usual time and skip the forgotten dose. Do not take a double or a larger dose to make up with a forgotten dose (s). Repeated skipping is to be avoided.
Stop Drug Consumption Do not stop taking Nebivolol without consulting your doctor first. If the medication is terminated abruptly, the patient may experience dangerous worsening of the symptoms. This concerns especially the patients with angina pectoris.
Possible Side Effects
General Information
Common Drug Side Effects When used for raised blood pressure: •Headache •Dizziness •Tiredness •An unusual itching or tingling feeling •Diarrhoea •Constipation •Nausea •Shortness of breath •Swollen hands or feet
Rare Drug Side Effects when used for raised blood pressure: •Slow heartbeat or other heart complaints •Low blood pressure •Abnormal vision •Impotence (difficulty in getting an erection) •Depressive feelings •Indigestion, gas in stomach or bowel •Vomiting •Skin rash •Tightening of the chest, difficulty in breathing or wheezing •Nightmares •In a clinical study for chronic heart failure, the side effects seen were slow heart beat, dizziness, worsening of heart failure, low blood pressure (such as feeling faint when getting up quickly), inability to tolerate medicine, irregular heart beat, swelling (such as swollen ankles).
Very Rare Drug Side Effects •Fainting •Psoriasis aggravated
Drug Side Effects Symptoms •Angioedema: swelling of the skin of the face or extremities, lips, tongue, mucous membranes of the throat and airway, resulting in shortness of breath or difficulty to swallow – contact a doctor immediately! •Hypersensitivity
How to Store the Medicine
How to Store the Medicine Keep out of the reach and sight of children. Do not use Nebivolol after the expiry date which is stated on the carton after . The expiry date refers to the last day of that month. Do not store above 30°C. Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.

HYDROCHLOROTHIAZIDE

Information for patients
Drug Information Hydrochlorothiazide, a 'water pill,' is used to treat high blood pressure and fluid retention caused by various conditions, including heart disease. It causes the kidneys to get rid of unneeded water and salt from the body into the urine. This medicine is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.Hydrochlorothiazide may also be used to treat patients with diabetes insipidus and certain electrolyte disturbances and to prevent kidney stones in patients with high levels of calcium in their blood. Talk to your doctor about the possible risks of using this medicine for your condition.
Drug Alert
Alert You should not use this medication if you are allergic to hydrochlorothiazide or if you are unable to urinate. Before using hydrochlorothiazide, tell your doctor if you have liver disease, kidney disease, glaucoma, asthma or allergies, gout, diabetes, or if you are allergic to sulfa drugs or penicillin. Avoid drinking alcohol, which can increase some of the side effects of hydrochlorothiazide. Avoid becoming overheated or dehydrated during exercise and in hot weather. Follow your doctor's instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough. There are many other drugs that can interact with hydrochlorothiazide. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you. If you are being treated for high blood pressure, keep using hydrochlorothiazide even if you feel fine. High blood pressure often has no symptoms.
Before Consuming the Medicine
Avoid Drug You should not use this medication if you are allergic to hydrochlorothiazide, or if you are unable to urinate. To make sure you can safely take hydrochlorothiazide, tell your doctor if you have any of these other conditions: kidney disease; liver disease; glaucoma; asthma or allergies; gout; diabetes; or an allergy to sulfa drugs. FDA pregnancy category B. Hydrochlorothiazide is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Hydrochlorothiazide can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
Drug Special Care tell your doctor and pharmacist if you are allergic to hydrochlorothiazide, sulfa drugs, or any other drugs. tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially other medicines for high blood pressure, anti-inflammatory medications such as ibuprofen (Motrin, Nuprin) or naproxen (Aleve), corticosteroids (e.g., prednisone), lithium (Eskalith, Lithobid), medications for diabetes, probenecid (Benemid), and vitamins. If you also are taking cholestyramine or colestipol, take it at least 1 hour after hydrochlorothiazide. tell your doctor if you have or have ever had diabetes, gout, or kidney, liver, thyroid, or parathyroid disease. tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking hydrochlorothiazide, call your doctor immediately. if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking hydrochlorothiazide. you should know that this drug may make you drowsy. Do not drive a car or operate machinery until you know how this drug affects you. remember that alcohol can add to the drowsiness caused by this drug. plan to avoid unnecessary or prolonged exposure to sunlight and to wear protective clothing, sunglasses, and sunscreen. Hydrochlorothiazide may make your skin sensitive to sunlight.
Drug Drug Interactions lithium (Eskalith, Lithobid); digoxin (Lanoxin); cholestyramine (Prevalite, Questran) or colestipol (Colestid); steroids (prednisone and others); other blood pressure medications; NSAIDs (non-steroidal anti-inflammatory drugs) such as aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn, Naprelan, Treximet), celecoxib (Celebrex), diclofenac (Arthrotec, Cambia, Cataflam, Voltaren, Flector Patch, Pennsaid, Solareze), indomethacin (Indocin), meloxicam (Mobic), and others; or insulin or oral diabetes medication.
Drug Pregnancy Interaction
Drug Breast feeding Interaction
Drug Machinery Interaction
Drug More Information Follow your doctor's directions. They may include following a daily exercise program or a low-salt or low-sodium diet, potassium supplements, and increased amounts of potassium-rich foods (e.g., bananas, prunes, raisins, and orange juice) in your diet.
How to take the Medicine
Consumption Info Drinking alcohol can increase certain side effects of hydrochlorothiazide. Avoid becoming overheated or dehydrated during exercise and in hot weather. Follow your doctor's instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough.
Drug quanitty Usual Adult Hydrochlorothiazide Dose for Edema: 25 to 100 mg orally as a single or divided dose. Usual Adult Dose for Hypertension: Initial dose: 25 mg orally once a day. Maintenance dose: May increase to 50 mg orally as a single or 2 divided doses. Usual Adult Hydrochlorothiazide Dose for Nephrocalcinosis: Initial: 25 mg orally once a day Maintenance dose: May increase to 50 mg twice a day Usual Adult Dose for Osteoporosis: Initial: 25 mg orally once a day Maintenance dose: May increase to 50 mg per day Usual Adult Hydrochlorothiazide Dose for Diabetes Insipidus: Initial: 50 mg orally once a day Maintenance dose: May increase to 100 mg per day
Drug Dose Hydrochlorothiazide comes as a tablet and liquid to take by mouth. It usually is taken once or twice a day. If you are to take it once a day, take it in the morning; if you are to take it twice a day, take it in the morning and in the late afternoon to avoid going to the bathroom during the night. Take this medication with a meal or snack. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take hydrochlorothiazide exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Hydrochlorothiazide controls high blood pressure but does not cure it. Continue to take hydrochlorothiazide even if you feel well. Do not stop taking hydrochlorothiazide without talking to your doctor.
Excess Drug Consumption Take the missed dose as soon as you remember it. However, if it is almost time for your next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
Forgot Drug Consumption Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
Stop Drug Consumption
Possible Side Effects
General Information sore throat with fever unusual bleeding or bruising severe skin rash with peeling skin difficulty breathing or swallowing
Common Drug Side Effects muscle weakness dizziness cramps thirst stomach pain nausea vomiting diarrhea loss of appetite headache hair loss
Rare Drug Side Effects
Very Rare Drug Side Effects
Drug Side Effects Symptoms
How to Store the Medicine
How to Store the Medicine Keep this medicine in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Do not allow the liquid to freeze. Throw away any medicine that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medicine.

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