NERVERICH CAPSULE

Manufacturer : IND-INDCHEMIE
Composition : ALPHA LIPOIC ACID-100MG+GAMMA LINOLENIC ACID-60MG+PYRIDOXINE (VITB6)-5MG+CHROMIUM-50MCG+METHYLCOBALAMIN-1500MCG
Dose Form : CAPSULE
Description : NERVERICH CAPS
Route Of Administration : ORAL
Pack : 10
In stock
SKU
NER0002
₹188.50
Manufacturer : IND-INDCHEMIE
Composition : ALPHA LIPOIC ACID-100MG+GAMMA LINOLENIC ACID-60MG+PYRIDOXINE (VITB6)-5MG+CHROMIUM-50MCG+METHYLCOBALAMIN-1500MCG
Dose Form : CAPSULE
Description : NERVERICH CAPS
Route Of Administration : ORAL
Pack : 10

Drug Ingredient Information

ALPHA LIPOIC ACID-100MG+GAMMA LINOLENIC ACID-60MG+PYRIDOXINE (VITB6)-5MG+CHROMIUM-50MCG+METHYLCOBALAMIN-1500MCG

ALPHA LIPOIC ACID

Information for patients
Drug Information Alpha-lipoic acid (ALA) has been used as an antioxidant for the treatment of diabetes and HIV. It also has been used for cancer, liver ailments, and various other conditions
Drug Alert
Alert People with diabetes should be careful to check their blood sugar levels because alpha-lipoic acid might lower blood sugar.
Before Consuming the Medicine
Avoid Drug
Drug Special Care
Drug Drug Interactions
Drug Pregnancy Interaction Not enough is known about the use of alpha-lipoic acid during pregnancy and breast-feeding. Stay on the safe side and avoid use.
Drug Breast feeding Interaction
Drug Machinery Interaction
Drug More Information
How to take the Medicine
Consumption Info
Drug quanitty The best dose for neuropathy is 600 mg daily. Between 50 to 100 mg is sufficient for antioxidant purposes. You can buy it in doses of 30 to 100 mg tablets. Studies are mixed about whether or not to take ALA with meals. General antioxidant support: 20 to 50 mg per day Diabetes and diabetic neuropathy: 800 mg per day in divided doses
Drug Dose
Excess Drug Consumption
Forgot Drug Consumption
Stop Drug Consumption
Possible Side Effects
General Information Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Although not all side effects are known, alpha-lipoic acid is thought to be possibly safe when taken as directed.
Common Drug Side Effects nausea; or skin rash.
Rare Drug Side Effects low blood sugar--headache, hunger, weakness, sweating, confusion, irritability, dizziness, fast heart rate, or feeling jittery; or a light-headed feeling, like you might pass out.
Very Rare Drug Side Effects
Drug Side Effects Symptoms
How to Store the Medicine
How to Store the Medicine Store in cool, dry place. Avoid humidity. In particular , alpha lipoic acid is is stored under 5 degrees

GAMMA LINOLENIC ACID

Information for patients
Drug Information Gamma-linolenic acid or GLA (?-Linolenic acid), is a fatty acid found primarily in vegetable oils. When acting on GLA, 5-lipoxygenase produces no leukotrienes and the conversion by the enzyme of arachidonic acid to leukotrienes is inhibited.
Drug Alert
Alert
Before Consuming the Medicine
Avoid Drug
Drug Special Care
Drug Drug Interactions
Drug Pregnancy Interaction
Drug Breast feeding Interaction
Drug Machinery Interaction
Drug More Information Gamma linolenic acid (GLA) is used for conditions that affect the skin including systemic sclerosis, psoriasis, and eczema. It is also used for rheumatoid arthritis (RA), polyps in the mouth, high cholesterol and other blood fats, heart disease, metabolic syndrome (Syndrome-X), diabetic nerve pain, attention deficit-hyperactivity disorder (ADHD), depression, depression after childbirth, chronic fatigue syndrome (CFS), and hay fever (allergic rhinitis). Some people use it to prevent cancer and to help breast cancer patients respond faster to treatment with the drug tamoxifen.
How to take the Medicine
Consumption Info
Drug quanitty
Drug Dose
Excess Drug Consumption
Forgot Drug Consumption
Stop Drug Consumption
Possible Side Effects
General Information
Common Drug Side Effects
Rare Drug Side Effects
Very Rare Drug Side Effects
Drug Side Effects Symptoms
How to Store the Medicine
How to Store the Medicine

PYRIDOXINE (VITB6)

Information for patients
Drug Information Pyridoxine is vitamin B6. Vitamins occur naturally in foods such as meat, poultry, nuts, whole grains, bananas, and avocados. Vitamin B6 is important for many processes in the body. Pyridoxine is used to treat or prevent vitamin B6 deficiency. It is also used to treat a certain type of anemia (lack of red blood cells). Pyridoxine injection is also used to treat some types of seizure in babies. Pyridoxine taken by mouth (oral) is available without a prescription. Injectable pyridoxine must be given by a healthcare professional.
Drug Alert
Alert do not exceed stated dose
Before Consuming the Medicine
Avoid Drug Many drugs may alter the metabolism or bioavailability of pyridoxine, including isoniazid, penicillamine and oral contraceptives, which may increase the requirements for pyridoxine. Pyridoxine hydrochloride may reduce the effect of levodopa, a drug used in the treatment of Parkinsons Disease unless a dopa decarboxylase inhibitor is also given.
Drug Special Care You should not use pyridoxine if you have ever had an allergic reaction to it.
Drug Drug Interactions Many drugs may alter the metabolism or bioavailability of pyridoxine, including isoniazid, penicillamine and oral contraceptives, which may increase the requirements for pyridoxine. Pyridoxine hydrochloride may reduce the effect of levodopa, a drug used in the treatment of Parkinsons Disease unless a dopa decarboxylase inhibitor is also given.
Drug Pregnancy Interaction Data on exposed pregnancies indicate no adverse effects of pyridoxine in therapeutic doses on pregnancy or the health of the foetus or newborn child, or during lactation. Animal studies are insufficient with respect to effects on pregnancy, embryonal/foetal development, parturition or postnatal development. Caution should be exercised when prescribing to pregnant women.
Drug Breast feeding Interaction Data on exposed pregnancies indicate no adverse effects of pyridoxine in therapeutic doses on pregnancy or the health of the foetus or newborn child, or during lactation.
Drug Machinery Interaction no data
Drug More Information Long term administration of large doses of pyridoxine is associated with the development of severe peripheral neuritis.
How to take the Medicine
Consumption Info Pyridoxine Hydrochloride is used for isoniazid-induced peripheral neuritis, idiopathic sideroblastic anaemia and Vitamin B6 deficiency states.
Drug quanitty 50mg three times a day
Drug Dose no data
Excess Drug Consumption a) Symptoms – None reported b) Treatment – no treatment necessary
Forgot Drug Consumption no data
Stop Drug Consumption no data
Possible Side Effects
General Information As well as its needed effects, pyridoxine may cause unwanted side effects that require medical attention
Common Drug Side Effects With large doses Clumsiness numbness of hands or feet
Rare Drug Side Effects Nervous system side effects have included sensory neuropathy with axonal degeneration. The adverse neurologic side effects have been reported following a single large dose (10 g) administered intravenously. It may rarely occur following chronic administration of lower doses. Peripheral sensory neuropathy has also been reported
Very Rare Drug Side Effects Dermatologic side effects have included allergic contact dermatitis. Photosensitivity has been confirmed in a female patient taking pyridoxine 100 mg orally daily
Drug Side Effects Symptoms no data
How to Store the Medicine
How to Store the Medicine Store below 25°C Protect from light and moisture.

CHROMIUM

Information for patients
Drug Information Treating or preventing chromium deficiency. Chromium Picolinate is a mineral. It works by increasing the blood levels of chromium.
Drug Alert
Alert
Before Consuming the Medicine
Avoid Drug • Diabetes patients - Chromium Picolinate may affect your blood sugar. Check blood sugar levels closely and ask your doctor before adjusting the dose of your diabetes medicine. • PREGNANCY and BREAST-FEEDING: If you become pregnant, discuss with your doctor the benefits and risks of using Chromium Picolinate during pregnancy. If you are or will be breast-feeding while you are using Chromium Picolinate, check with your doctor or pharmacist to discuss the risks to your baby. • you are allergic to any ingredient in Chromium Picolinate Contact your doctor or health care provider right away if any of these apply to you.
Drug Special Care Some medical conditions may interact with Chromium Picolinate. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you: • if you are pregnant, planning to become pregnant, or are breast-feeding • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement • if you have allergies to medicines, foods, or other substances Some MEDICINES MAY INTERACT with Chromium Picolinate. However, no specific interactions with Chromium Picolinate are known at this time. This may not be a complete list of all interactions that may occur. Ask your health care provider if Chromium Picolinate may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
Drug Drug Interactions no data available
Drug Pregnancy Interaction : If you become pregnant, discuss with your doctor the benefits and risks of using Chromium Picolinate during pregnancy
Drug Breast feeding Interaction . If you are or will be breast-feeding while you are using Chromium Picolinate, check with your doctor or pharmacist to discuss the risks to your baby.
Drug Machinery Interaction no data available
Drug More Information no data available
How to take the Medicine
Consumption Info no data available
Drug quanitty no data available
Drug Dose How to use Chromium Picolinate: Use Chromium Picolinate as directed by your doctor. Check the label on the medicine for exact dosing instructions. • Take Chromium Picolinate with food. • Take Chromium Picolinate with a full glass of water (8 oz/240 mL). • If you miss taking a dose of Chromium Picolinate for 1 or more days, there is no cause for concern. If your doctor recommended that you take it, try to remember your dose every day. Ask your health care provider any questions you may have about how to use Chromium Picolinate.
Excess Drug Consumption Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include kidney or liver damage; loss of consciousness; seizures; upset stomach; vomiting.
Forgot Drug Consumption Contact Your doctor
Stop Drug Consumption Do not stop the drug untill your doctor says you to do so.
Possible Side Effects
General Information no data available
Common Drug Side Effects All medicines may cause side effects, but many people have no, or minor, side effects. When used in small doses, no COMMON side effects have been reported with this product. Seek medical attention right away if any of these SEVERE side effects occur:Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue).This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency,
Rare Drug Side Effects no data available
Very Rare Drug Side Effects no data available
Drug Side Effects Symptoms no data available
How to Store the Medicine
How to Store the Medicine Store in a cool and dry place.

METHYLCOBALAMIN

Information for patients
Drug Information Vitamin B12, is used to treat vitamin B12 deficiency, cyanide poisoning, and hereditary deficiency of transcobalamin II.[3] It is also given as part of the schilling test for detecting pernicious anemia.[3] For cyanide poisoning, large amount may be given intravenously, and sometimes in combination with sodium thiosulfate.[4] The mechanism of action is straightforward: the hydroxycobalamin hydroxide ligand is displaced by the toxic cyanide ion, and the resulting harmless B12 complex is excreted in urine. In the United States, the Food and Drug Administration approved (in 2006) the use of hydroxocobalamin for acute treatment of cyanide poisoning.[5] High vitamin B12 level in elderly individuals may protect against brain atrophy or shrinkage, associated with Alzheimer's disease and impaired cognitive function.[6] High-dose administration of Vitamin B12 has been additionally validated to stimulate the activity of the body's TH1 suppressor T-Cells, which then down-regulates the over-production of the allagen antibody 1gE in allergic individuals.
Drug Alert
Alert no data available
Before Consuming the Medicine
Avoid Drug no data available
Drug Special Care Vitamin B12 supplements in theory should be avoided in people sensitive or allergic to cobalamin, cobalt, or any other product ingredients. However, direct allergy to a vitamin or nutrient is extremely rare, and if reported, other causes should be sought.
Drug Drug Interactions Aminosalicylic acid (para-aminosalicylic acid, PAS, Paser): Aminosalicylic acid can reduce oral vitamin B12 absorption, possibly by as much as 55%, as part of a general malabsorption syndrome. Megaloblastic changes, and occasional cases of symptomatic anemia have occurred, usually after doses of 8 to 12 g/day for several months. Vitamin B12 levels should be monitored in people taking aminosalicylic acid for more than one month. Antibiotics: An increased bacterial load can bind significant amounts of vitamin B12 in the gut, preventing its absorption. In people with bacterial overgrowth of the small bowel, antibiotics such as metronidazole (Flagyl) can actually improve vitamin B12 status. The effects of most antibiotics on gastrointestinal bacteria are unlikely to have clinically significant effects on vitamin B12 levels. Hormonal contraception: The data regarding the effects of oral contraceptives on vitamin B12serum levels are conflicting. Some studies have found reduced serum levels in oral contraceptive users, but others have found no effect despite use of oral contraceptives for up to 6 months. When oral contraceptive use is stopped, normalization of vitamin B12 levels usually occurs. Lower vitamin B12serum levels seen with oral contraceptives probably are not clinically significant. Chloramphenicol (Chloromycetin): Limited case reports suggest that chloramphenicol can delay or interrupt the reticulocyte response to supplemental vitamin B12 in some patients. Blood counts should be monitored closely if this combination cannot be avoided. Cobalt irradiation: Cobalt irradiation of the small bowel can decrease gastrointestinal (GI) absorption of vitamin B12. Colchicine: Colchicine in doses of 1.9 to 3.9 mg/day can disrupt normal intestinal mucosal function, leading to malabsorption of several nutrients, including vitamin B12. Lower doses do not seem to have a significant effect on vitamin B12 absorption after 3 years of colchicine therapy. The significance of this interaction is unclear. Vitamin B12 levels should be monitored in people taking large doses of colchicine for prolonged periods. Colestipol (Colestid), cholestyramine (Questran): These resins used for sequestering bile acids to decrease cholesterol, can decrease gastrointestinal (GI) absorption of vitamin B12. It is unlikely this interaction will deplete body stores of vitamin B12 unless there are other factors contributing to deficiency. In a group of children treated with cholestyramine for up to 2.5 years, there was not any change in serum vitamin B12 levels. Routine supplements are not necessary. H2-receptor antagonists: include cimetidine (Tagamet), famotidine (Pepcid), nizatidine (Axid), and ranitidine (Zantac). Reduced secretion of gastric acid and pepsin produced by H2 blockers can reduce absorption of protein-bound (dietary) vitamin B12, but not of supplemental vitamin B12. Gastric acid is needed to release vitamin B12 from protein for absorption. Clinically significant vitamin B12 deficiency and megaloblastic anemia are unlikely, unless H2 blocker therapy is prolonged (2 years or more), or the person's diet is poor. It is also more likely if the person is rendered achlorhydric(with complete absence of gastric acid secretion), which occurs more frequently with proton pump inhibitors than H2 blockers. Vitamin B12 levels should be monitored in people taking high doses of H2 blockers for prolonged periods. Metformin (Glucophage): Metformin may reduce serum folic acid and vitamin B12 levels. These changes can lead to hyperhomocysteinemia, adding to the risk of cardiovascular disease in people with diabetes.[citation needed] There are also rare reports of megaloblastic anemia in people who have taken metformin for five years or more. Reduced serum levels of vitamin B12 occur in up to 30% of people taking metformin chronically.[20][21] However, clinically significant deficiency is not likely to develop if dietary intake of vitamin B12 is adequate. Deficiency can be corrected with vitamin B12 supplements even if metformin is continued. The metformin-induced malabsorption of vitamin B12 is reversible by oral calcium supplementation.[22] The general clinical significance of metformin upon B12 levels is as yet unknown.[23] Neomycin: Absorption of vitamin B12 can be reduced by neomycin, but prolonged use of large doses is needed to induce pernicious anemia. Supplements are not usually needed with normal doses. Nicotine: Nicotine can reduce serum vitamin B12 levels. The need for vitamin B12 supplementation in smokers has not been adequately studied. Nitrous oxide: Nitrous oxide inactivates the cobalamin form of vitamin B12 by oxidation. Symptoms of vitamin B12 deficiency, including sensory neuropathy, myelopathy, and encephalopathy, can occur within days or weeks of exposure to nitrous oxide anesthesia in people with subclinical vitamin B12 deficiency. Symptoms are treated with high doses of vitamin B12, but recovery can be slow and incomplete. People with normal vitamin B12 levels have sufficient vitamin B12 stores to make the effects of nitrous oxide insignificant, unless exposure is repeated and prolonged (such as recreational use). Vitamin B12 levels should be checked in people with risk factors for vitamin B12 deficiency prior to using nitrous oxide anesthesia. Chronic nitrous oxide B12 poisoning (usually from use of nitrous oxide as a recreational drug), however, may result in B12 functional deficiency even with normal measured blood levels of B12.[24] Phenytoin (Dilantin), phenobarbital, primidone (Mysoline): These anticonvulsants have been associated with reduced vitamin B12 absorption, and reduced serum and cerebrospinal fluidlevels in some patients. This may contribute to the megaloblastic anemia, primarily caused by folate deficiency, associated with these drugs. It is also suggested that reduced vitamin B12 levels may contribute to the neuropsychiatric side effects of these drugs. Patients should be encouraged to maintain adequate dietary vitamin B12 intake. Folate and vitamin B12 status should be checked if symptoms of anemia develop. Proton pump inhibitors (PPIs): The PPIs include omeprazole (Prilosec, Losec), lansoprazole(Prevacid), rabeprazole (Aciphex), pantoprazole (Protonix, Pantoloc), and esomeprazole (Nexium). The reduced secretion of gastric acid and pepsin produced by PPIs can reduce absorption of protein-bound (dietary) vitamin B12, but not supplemental vitamin B12. Gastric acid is needed to release vitamin B12 from protein for absorption. Reduced vitamin B12 levels may be more common with PPIs than with H2-blockers, because they are more likely to produce achlorhydria (complete absence of gastric acid secretion). However, clinically significant vitamin B12 deficiency is unlikely, unless PPI therapy is prolonged (2 years or more) or dietary vitamin intake is low. Vitamin B12 levels should be monitored in people taking high doses of PPIs for prolonged periods. Zidovudine (AZT, Combivir, Retrovir): Reduced serum vitamin B12 levels may occur when zidovudine therapy is started. This adds to other factors that cause low vitamin B12 levels in people with HIV, and might contribute to the hematological toxicity associated with zidovudine. However, the data suggest vitamin B12 supplements are not helpful for people taking zidovudine.[citation needed] Folic acid: Folic acid, particularly in large doses, can mask vitamin B12 deficiency by completely correcting hematological abnormalities. In vitamin B12 deficiency, folic acid can produce complete resolution of the characteristic megaloblastic anemia, while allowing potentially irreversible neurological damage (from continued inactivity of methylmalonyl mutase) to progress. Thus, vitamin B12 status should be determined before folic acid is given as monotherapy. Potassium: Potassium supplements can reduce absorption of vitamin B12 in some people. This effect has been reported with potassium chloride and, to a lesser extent, with potassium citrate. Potassium might contribute to vitamin B12 deficiency in some people with other risk factors, but routine supplements are not necessary.[
Drug Pregnancy Interaction no data available
Drug Breast feeding Interaction no data available
Drug Machinery Interaction no data available
Drug More Information Alcohol (ethanol): Excessive alcohol intake lasting longer than two weeks can decrease vitamin B12 absorption from the gastrointestinal tract.[c
How to take the Medicine
Consumption Info no data available
Drug quanitty The dietary reference intake for an adult ranges from 2 to 3 µg per day.[9] Vitamin B12 is believed to be safe when used orally in amounts that do not exceed the recommended dietary allowance (RDA). There have also been studies that showed no adverse consequences of doses above the RDA.[10] The RDA for vitamin B12 in pregnant women is 2.6 µg per day and 2.8 µg during lactation periods.[citation needed] There is insufficient reliable information available about the safety of consuming greater amounts of vitamin B12 during pregnancy. The Vegan Society, the Vegetarian Resource Group, and the Physicians Committee for Responsible Medicine, among others, recommend that vegans either consistently eat foods fortified with B12 or take a daily or weekly B12 supplement.[11][12][13] Fortified breakfast cereals are a particularly valuable source of vitamin B12 for vegetarians and vegans. In addition, adults age 51 and older are recommended to consume B12 fortified food or supplements to meet the RDA, because they are a population at an increased risk of deficiency
Drug Dose Can you take too much? No. Unlike other supplements which you can overdose on, your body doesn’t store excess vitamin B12. But you don’t want to waste it. I usually go with ~1cc every week or so.
Excess Drug Consumption no data available
Forgot Drug Consumption contact your doctor
Stop Drug Consumption do not stop the medicine untill adviced by your doctor
Possible Side Effects
General Information no data available
Common Drug Side Effects Vitamin B12 has extremely low toxicity and even taking it in enormous doses appears not to be harmful to healthy individuals.[17][18] Hematologic: Peripheral vascular thrombosis has been reported. Treatment of vitamin B12 deficiency can unmask polycythemia vera, which is characterized by an increase in blood volume and the number of red blood cells. The correction of megaloblastic anemia with vitamin B12 can result in fatal hypokalemia and gout in susceptible individuals, and it can obscure folate deficiency in megaloblastic anemia. Caution is warranted. Leber's disease: Vitamin B12 in the form of cyanocobalamin is contraindicated in early Leber's disease, which is hereditary optic nerve atrophy. Cyanocobalamin can cause severe and swift optic atrophy, but other forms of vitamin B12 are available. However, the sources of this statement are not clear, while an opposing view[19] concludes: "The clinical picture of optic neuropathy associated with vitamin B12 deficiency shows similarity to that of Leber's disease optic neuropathy. Both involve the nerve fibres of the papillomacular bundle. The present case reports suggest that optic neuropathy in patients carrying a primary LHON mtDNA mutation may be precipitated by vitamin B12 deficiency. Therefore, known carriers should take care to have an adequate dietary intake of vitamin B12 and malabsorption syndromes like those occurring in familial pernicious anaemia or after gastric surgery should be excluded."
Rare Drug Side Effects no data available
Very Rare Drug Side Effects no data available
Drug Side Effects Symptoms no data available
How to Store the Medicine
How to Store the Medicine Precautions: Keep away from heat. Keep away from sources of ignition. Empty containers pose a fire risk, evaporate the residue under a fume hood. Ground all equipment containing material. Do not ingest. Do not breathe dust. If ingested, seek medical advice immediately and show the container or the label. Keep away from incompatibles such as oxidizing agents. Storage: Keep container tightly closed. Keep container in a cool, well-ventilated area.

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