NEUROBION FORTE INJECTION 2ML

Manufacturer : EME-E MERCK INDIA LTD
Composition : PYRIDOXINE (VITB6)-100MG+CYANOCOBALAMIN-1000MCG+NICOTINAMIDE-100MG+THIAMINE (VITB1)-100MG+RIBOFLAVIN (VITB2)-5MG+PANTHENOL-50MG
Dose Form : INJECTION
Description : NEUROBION FORTE INJ 2 ML
Route Of Administration : PARENTERAL
Pack : 1
In stock
SKU
NEU0132
₹86.38
Manufacturer : EME-E MERCK INDIA LTD
Composition : PYRIDOXINE (VITB6)-100MG+CYANOCOBALAMIN-1000MCG+NICOTINAMIDE-100MG+THIAMINE (VITB1)-100MG+RIBOFLAVIN (VITB2)-5MG+PANTHENOL-50MG
Dose Form : INJECTION
Description : NEUROBION FORTE INJ 2 ML
Route Of Administration : PARENTERAL
Pack : 1

Drug Ingredient Information

PYRIDOXINE (VITB6)-100MG+CYANOCOBALAMIN-1000MCG+NICOTINAMIDE-100MG+THIAMINE (VITB1)-100MG+RIBOFLAVIN (VITB2)-5MG+PANTHENOL-50MG

PYRIDOXINE (VITB6)

Information for patients
Drug Information Pyridoxine is vitamin B6. Vitamins occur naturally in foods such as meat, poultry, nuts, whole grains, bananas, and avocados. Vitamin B6 is important for many processes in the body. Pyridoxine is used to treat or prevent vitamin B6 deficiency. It is also used to treat a certain type of anemia (lack of red blood cells). Pyridoxine injection is also used to treat some types of seizure in babies. Pyridoxine taken by mouth (oral) is available without a prescription. Injectable pyridoxine must be given by a healthcare professional.
Drug Alert
Alert do not exceed stated dose
Before Consuming the Medicine
Avoid Drug Many drugs may alter the metabolism or bioavailability of pyridoxine, including isoniazid, penicillamine and oral contraceptives, which may increase the requirements for pyridoxine. Pyridoxine hydrochloride may reduce the effect of levodopa, a drug used in the treatment of Parkinsons Disease unless a dopa decarboxylase inhibitor is also given.
Drug Special Care You should not use pyridoxine if you have ever had an allergic reaction to it.
Drug Drug Interactions Many drugs may alter the metabolism or bioavailability of pyridoxine, including isoniazid, penicillamine and oral contraceptives, which may increase the requirements for pyridoxine. Pyridoxine hydrochloride may reduce the effect of levodopa, a drug used in the treatment of Parkinsons Disease unless a dopa decarboxylase inhibitor is also given.
Drug Pregnancy Interaction Data on exposed pregnancies indicate no adverse effects of pyridoxine in therapeutic doses on pregnancy or the health of the foetus or newborn child, or during lactation. Animal studies are insufficient with respect to effects on pregnancy, embryonal/foetal development, parturition or postnatal development. Caution should be exercised when prescribing to pregnant women.
Drug Breast feeding Interaction Data on exposed pregnancies indicate no adverse effects of pyridoxine in therapeutic doses on pregnancy or the health of the foetus or newborn child, or during lactation.
Drug Machinery Interaction no data
Drug More Information Long term administration of large doses of pyridoxine is associated with the development of severe peripheral neuritis.
How to take the Medicine
Consumption Info Pyridoxine Hydrochloride is used for isoniazid-induced peripheral neuritis, idiopathic sideroblastic anaemia and Vitamin B6 deficiency states.
Drug quanitty Treatment and prophylaxis of vitamin B<209>6<190> deficiency states Adult: Up to 150 mg daily. May also be given via SC, IM or IV routes. Sideroblastic anaemia Adult: Up to 400 mg daily. May also be given via SC, IM or IV routes.
Drug Dose to be taken in s.c ,i.m or i.v route.
Excess Drug Consumption no data
Forgot Drug Consumption Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
Stop Drug Consumption no data
Possible Side Effects
General Information As well as its needed effects, pyridoxine may cause unwanted side effects that require medical attention
Common Drug Side Effects With large doses Clumsiness numbness of hands or feet
Rare Drug Side Effects Nervous system side effects have included sensory neuropathy with axonal degeneration. The adverse neurologic side effects have been reported following a single large dose (10 g) administered intravenously. It may rarely occur following chronic administration of lower doses. Peripheral sensory neuropathy has also been reported
Very Rare Drug Side Effects Dermatologic side effects have included allergic contact dermatitis. Photosensitivity has been confirmed in a female patient taking pyridoxine 100 mg orally daily
Drug Side Effects Symptoms no data
How to Store the Medicine
How to Store the Medicine no data..

CYANOCOBALAMIN

Information for patients
Drug Information Cyanocobalamin is indicated for vitamin B12 deficiencies due to malabsorption which may be associated with the following conditions: Addisonian (pernicious) anemia Gastrointestinal pathology, dysfunction, or surgery, including gluten enteropathy or sprue, small bowel bacteria overgrowth, total or partial gastrectomy Fish tapeworm infestation Malignancy of pancreas or bowel Folic acid deficiency It may be possible to treat the underlying disease by surgical correction of anatomic lesions leading to small bowel bacterial overgrowth, expulsion of fish tapeworm, discontinuation of drugs leading to vitamin malabsorption (see Drug Interactions), use of a gluten-free diet in nontropical sprue, or administration of antibiotics in tropical sprue. Such measures remove the need for long-term administration of cyanocobalamin. Requirements of vitamin B12 in excess of normal (due to pregnancy, thyrotoxicosis, hemolytic anemia, hemorrhage, malignancy, hepatic and renal disease) can usually be met with oral supplementation. Cyanocobalamin Injection, USP is also suitable for the vitamin B12 absorption test ( Schilling test).
Drug Alert
Alert Patients with early Leber's disease (hereditary optic nerve atrophy) who were treated with cyanocobalamin suffered severe and swift optic atrophy. Hypokalemia and sudden death may occur in severe megaloblastic anemia which is treated intensely. Anaphylactic shock and death have been reported after parenteral vitamin B12 administration. An intradermal test dose is recommended before Cyanocobalamin Injection, USP is administered to patients suspected of being sensitive to this drug. This product contains Benzyl Alcohol. Benzyl Alcohol has been reported to be associated with a fatal "Gasping Syndrome" in premature infants. This product contains aluminum that may be toxic. Aluminum may reach toxic levels with prolonged parenteral administration if kidney function is impaired. Premature neonates are particularly at risk because their kidneys are immature, and they require large amounts of calcium and phosphate solutions, which contain aluminum. Research indicates that patients with impaired kidney function, including premature neonates, who receive parenteral levels of aluminum at greater than 4 to 5 mcg/kg/day accumulate aluminum at levels associated with central nervous system and bone toxicity. Tissue loading may occur at even lower rates of administration.
Before Consuming the Medicine
Avoid Drug Sensitivity to cobalt and/or vitamin B12 is a contraindication.
Drug Special Care General Precautions: Vitamin B12 deficiency that is allowed to progress for longer than 3 months may produce permanent degenerative lesions of the spinal cord. Doses of folic acid greater than 0.1 mg per day may result in hematologic remission in patients with vitamin B12 deficiency. Neurologic manifestations will not be prevented with folic acid, and if not treated with vitamin B12, irreversible damage will result. Doses of cyanocobalamin exceeding 10 mcg daily may produce hematologic response in patients with folate deficiency. Indiscriminate administration may mask the true diagnosis. Information for Patients: Patients with pernicious anemia should be informed that they will require monthly injections of vitamin B12 for the remainder of their lives. Failure to do so will result in return of the anemia and in development of incapacitating and irreversible damage to the nerves of the spinal cord. Also, patients should be warned about the danger of taking folic acid in place of vitamin B12, because the former may prevent anemia but allow progression of subacute combined degeneration. A vegetarian diet which contains no animal products (including milk products or eggs) does not supply any vitamin B12. Patients following such a diet, should be advised to take oral vitamin B12 regularly. The need for vitamin B12 is increased by pregnancy and lactation. Deficiency has been recognized in infants of vegetarian mothers who were breast fed, even though the mothers had no symptoms of deficiency at the time. Laboratory Tests: During the initial treatment of patients with pernicious anemia, serum potassium must be observed closely the first 48 hours and potassium replaced if necessary. Hematocrit, reticulocyte count, vitamin B12, folate and iron levels should be obtained prior to treatment. Hematocrit and reticulocyte counts should be repeated daily from the fifth to seventh days of therapy and then frequently until the hematocrit is normal. If folate levels are low, folic acid should also be administered. If reticulocytes have not increased after treatment or if reticulocyte counts do not continue at least twice normal as long as the hematocrit is less than 35%, diagnosis or treatment should be reevaluated. Repeat determinations of iron and folic acid may reveal a complicating illness that might inhibit the response of the marrow. Patients with pernicious anemia have about 3 times the incidence of carcinoma of the stomach as the general population, so appropriate tests for this condition should be carried out when indicated. Drug/Laboratory Test Interactions: Persons taking most antibiotics, methotrexate and pyrimethamine invalidate folic acid and vitamin B12 diagnostic blood assays. Colchicine para-aminosalicylic acid and heavy alcohol intake for longer than 2 weeks may produce malabsorption of vitamin B12. Carcinogenesis, Mutagenesis, Impairment of Fertility: Long term studies in animals to evaluate carcinogenic potential have not been done. There is no evidence from long-term use in patients with pernicious anemia that cyanocobalamin is carcinogenic. Pernicious anemia is associated with an increased incidence of carcinoma of the stomach, but this is believed to be related to the underlying pathology and not to treatment with cyanocobalamin. Pregnancy: Teratogenic Effects. Pregnancy Category C: Adequate and well-controlled studies have not been done in pregnant women. However, vitamin B12 is an essential vitamin and requirements are increased during pregnancy. Amounts of vitamin B12 that are recommended by the Food and Nutrition Board, National Academy of Science-National Research Council for pregnant women (4 mcg daily) should be consumed during pregnancy. Nursing Mothers: Vitamin B12 is known to be excreted in human milk. Amounts of vitamin B12 that are recommended by the Food and Nutrition Board, National Academy of Science-National Research Council for lactating women (4 mcg daily) should be consumed during lactation. Pediatric Use: Intake in children should be in the amount (0.5 to 3 mcg daily) recommended by the Food and Nutrition Board, National Academy of Science-National Research Council.
Drug Drug Interactions no data available
Drug Pregnancy Interaction Pregnancy: Teratogenic Effects. Pregnancy Category C: Adequate and well-controlled studies have not been done in pregnant women. However, vitamin B12 is an essential vitamin and requirements are increased during pregnancy. Amounts of vitamin B12 that are recommended by the Food and Nutrition Board, National Academy of Science-National Research Council for pregnant women (4 mcg daily) should be consumed during pregnancy.
Drug Breast feeding Interaction Vitamin B12 is known to be excreted in human milk. Amounts of vitamin B12 that are recommended by the Food and Nutrition Board, National Academy of Science-National Research Council for lactating women (4 mcg daily) should be consumed during lactation.
Drug Machinery Interaction no data available
Drug More Information no data available
How to take the Medicine
Consumption Info no data available
Drug quanitty Avoid using the intravenous route. Use of this product intravenously will result in almost all of the vitamin being lost in the urine. Pernicious Anemia: Parenteral vitamin B12 is the recommended treatment and will be required for the remainder of the patient's life. The oral form is not dependable. A dose of 100 mcg daily for 6 or 7 days should be administered by intramuscular or deep subcutaneous injection. If there is clinical improvement and if a reticulocyte response is observed, the same amount may be given on alternate days for seven doses, then every 3 to 4 days for another 2 to 3 weeks. By this time hematologic values should have become normal. This regimen should be followed by 100 mcg monthly for life. Folic acid should be administered concomitantly if needed. Patients with Normal Intestinal Absorption: Where the oral route is not deemed adequate, initial treatment similar to that for patients with pernicious anemia may be indicated depending on the severity of the deficiency. Chronic treatment should be with an oral B12 preparation. If other vitamin deficiencies are present, they should be treated. Schilling Test: The flushing dose is 1000 mcg. Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit.
Drug Dose no data available
Excess Drug Consumption Dail 1066. OR Contact doctor immediately
Forgot Drug Consumption Contact Your doctor
Stop Drug Consumption Do not stop the drug untill your doctor says you to do so.
Possible Side Effects
General Information no data available
Common Drug Side Effects Generalized: Anaphylactic shock and death have been reported with administration of parenteral vitamin B12 (see WARNINGS). Cardiovascular: Pulmonary edema and congestive heart failure early in treatment; peripheral vascular thrombosis. Hematological: Polycythemia vera Gastrointestinal: Mild transient diarrhea Dermatological: Itching; transitory exanthema Miscellaneous: Feeling of swelling of entire body
Rare Drug Side Effects no data available
Very Rare Drug Side Effects no data available
Drug Side Effects Symptoms no data available
How to Store the Medicine
How to Store the Medicine Store in a cool and dry place.

NICOTINAMIDE

Information for patients
Drug Information
Drug Alert
Alert
Before Consuming the Medicine
Avoid Drug
Drug Special Care
Drug Drug Interactions
Drug Pregnancy Interaction
Drug Breast feeding Interaction
Drug Machinery Interaction
Drug More Information
How to take the Medicine
Consumption Info
Drug quanitty
Drug Dose
Excess Drug Consumption
Forgot Drug Consumption
Stop Drug Consumption
Possible Side Effects
General Information
Common Drug Side Effects
Rare Drug Side Effects
Very Rare Drug Side Effects
Drug Side Effects Symptoms
How to Store the Medicine
How to Store the Medicine

THIAMINE (VITB1)

Information for patients
Drug Information Wernicke-Korsakoff syndrome
Drug Alert
Alert no data available
Before Consuming the Medicine
Avoid Drug no data available
Drug Special Care Parenteral admin. Increased daily requirements in pregnancy and lactation.
Drug Drug Interactions May enhance the effect of neuromuscular blocking agents.
Drug Pregnancy Interaction Category A: Controlled studies in women fail to demonstrate a risk to the foetus in the 1st trimester (and there is no evidence of a risk in later trimesters), and the possibility of foetal harm remains remote. if dose > US RDA. Category C: Either studies in animals have revealed adverse effects on the foetus (teratogenic or embryocidal or other) and there are no controlled studies in women or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the foetus.
Drug Breast feeding Interaction no data available
Drug Machinery Interaction no data available
Drug More Information Should be taken with food.
How to take the Medicine
Consumption Info no data available
Drug quanitty no data available
Drug Dose Wernicke-Korsakoff syndrome Adult: Initially, 100 mg by slow IV Inj over 10 min, then 50-100 mg/day IM or IV until the patient can take oral thiamine. Incompatibility: Alkaline or neutral solutions and with oxidizing and reducing agents
Excess Drug Consumption Call 1066 or Contact your near emergency
Forgot Drug Consumption Contact your doctor
Stop Drug Consumption Do not stop taking medicine untill your doctor ask you to do so.
Possible Side Effects
General Information no data available
Common Drug Side Effects IV: Warm sensation, tingling, pruritus, pain, urticaria, weakness, sweating, nausea, restlessness, tightness of the throat, angioedema, respiratory distress, cyanosis, pulmonary oedema, GI bleeding, transient vasodilation and hypotension, vascular collapse. IM: Tenderness and induration. Potentially Fatal: Very rarely, fatal anaphylactic shock.
Rare Drug Side Effects no data available
Very Rare Drug Side Effects no data available
Drug Side Effects Symptoms no data available
How to Store the Medicine
How to Store the Medicine Store between 15-30°C.

RIBOFLAVIN (VITB2)

Information for patients
Drug Information
Drug Alert
Alert
Before Consuming the Medicine
Avoid Drug
Drug Special Care
Drug Drug Interactions
Drug Pregnancy Interaction
Drug Breast feeding Interaction
Drug Machinery Interaction
Drug More Information
How to take the Medicine
Consumption Info
Drug quanitty
Drug Dose
Excess Drug Consumption
Forgot Drug Consumption
Stop Drug Consumption
Possible Side Effects
General Information
Common Drug Side Effects
Rare Drug Side Effects
Very Rare Drug Side Effects
Drug Side Effects Symptoms
How to Store the Medicine
How to Store the Medicine

PANTHENOL

Information for patients
Drug Information Panthenol (also called pantothenol) is the alcohol analog of pantothenic acid (vitamin B5), and is thus a provitamin of B5. In organisms it is quickly oxidized to pantothenic acid. It is a viscous transparent liquid at room temperature. Panthenol is used as a moisturizer and to improve wound healing in pharmaceutical and cosmetic products. available as d.panthenol and l-panthenol.
Drug Alert
Alert
Before Consuming the Medicine
Avoid Drug no data
Drug Special Care no data
Drug Drug Interactions no data
Drug Pregnancy Interaction no data
Drug Breast feeding Interaction no data
Drug Machinery Interaction no data
Drug More Information no data
How to take the Medicine
Consumption Info
Drug quanitty
Drug Dose
Excess Drug Consumption
Forgot Drug Consumption
Stop Drug Consumption
Possible Side Effects
General Information no data
Common Drug Side Effects no data
Rare Drug Side Effects no data
Very Rare Drug Side Effects no data
Drug Side Effects Symptoms no data
How to Store the Medicine
How to Store the Medicine no data

Substitute Drugs

Write Your Own Review
You're reviewing:NEUROBION FORTE INJECTION 2ML
Your Rating

Get Captcha Image