| Information for
patients
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| Drug Information |
Nimesulide is a relatively COX-2 selective, non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties. Its approved indications are the treatment of acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea in adolescents and adults above 12 years old. Due to concerns about the risk of hepatotoxicity, nimesulide has been withdrawn from market in many countries.
Nimesulide is primarily indicated in conditions like Bursitis, Gynecological infections, Osteoarthritis, Rheumatoid arthritis, Tendinitis, Thrombophlebitis, Trauma, and can also be given in adjunctive therapy as an alternative drug of choice in Ent infections. |
| Drug Alert |
| Alert |
Nimesulide must be used with care among patients with a history of bleeding, with illnesses of the upper gastrointestinal tract and to subjects undergoing treatment with anticoagulants or drugs that inhibit platelet aggregation. The patients must be under direct medical supervision while taking substances with limited gastric tolerance at the same time. Since the drug is eliminated mainly through the kidneys, patient with the renal insufficiency must have a lower dosage depending on the glomerular filtration rate. |
| Before Consuming
the Medicine
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| Avoid Drug |
Nimesulide must be used with care among patients with a history of bleeding, with illnesses of the upper gastrointestinal tract and to subjects undergoing treatment with anticoagulants or drugs that inhibit platelet aggregation. The patients must be under direct medical supervision while taking substances with limited gastric tolerance at the same time. Since the drug is eliminated mainly through the kidneys, patient with the renal insufficiency must have a lower dosage depending on the glomerular filtration rate. The product must not be administered to the patient with severe renal insufficiency. The product can cause water retention, therefore it must not be administered to the patient with reduced cardiac function. Patients whose activity require alertness must take the product with care in case they notice drowsiness or vertigo during therapy . Cases of visual disturbances when using other non-steroidal anti-inflammatory drugs have been reported, If eye problems appear, the treatment must be interrupted and an eye examination must be performed. |
| Drug Special Care |
Nimesulide is contraindicated in conditions like GI ulceration, GI hemorrhage. |
| Drug Drug Interactions |
No data regarding the interactions of Nimesulide was found. |
| Drug Pregnancy Interaction |
Women should use the drug with caution during lactation and it is contraindicated during pregnancy |
| Drug Breast feeding Interaction |
Women should use the drug with caution during lactation and it is contraindicated during pregnancy |
| Drug Machinery Interaction |
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| Drug More Information |
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| How to take the
Medicine
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| Consumption Info |
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| Drug quanitty |
Adult Dosage ( >12 years. )
100.000 mg 100 (100) 12 hourly PO Increase upto 200mg bid.
Paedriatic Dosage ( 20 Kg. )
No data regarding the Paediatric dosage details of Nimesulide is available.
Neonatal Dosage ( 3 Kg. )
No data regarding the Neonatal dosage details of Nimesulide is available. |
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| Excess Drug Consumption |
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| Forgot Drug Consumption |
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| Possible Side
Effects
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| General Information |
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| Common Drug Side Effects |
Like most drugs in NSAID category, nimesulide is known to be hepatotoxic (damaging to the liver) in rare but unpredictable cases and should be taken with care. The patient information leaflet informs that the use of nimesulide in children under the age of 12 is contraindicated.
The drug has certain side effects, that can affect individuals in different ways. The following are some of the side effects, that are often associated with the drug:
Diarrhoea
Vomiting
Skin rash
Pruritis
Dizziness
Headache
Bitterness in mouth
Women should use the drug with caution during lactation and it is contraindicated during pregnancy. |
| Rare Drug Side Effects |
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| Very Rare Drug Side Effects |
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| Drug Side Effects Symptoms |
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| How to Store the
Medicine
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| How to Store the Medicine |
Stoe in a cool and dry place. |
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