NIMULID MR TABLET

Manufacturer : PAN-PANACEA BIOTEC LIMITED
Composition : NIMESULIDE-100MG+TIZANIDINE-2MG
Dose Form : TABLET
Description : NIMULID MR TAB
Route Of Administration : ORAL
Pack : 10
Out of stock
SKU
NIM0017
₹108.30

BANNED FOR SALE

As per the Drugs and Cosmetics Act, Ministry of Health and Family Welfare

Manufacturer : PAN-PANACEA BIOTEC LIMITED
Composition : NIMESULIDE-100MG+TIZANIDINE-2MG
Dose Form : TABLET
Description : NIMULID MR TAB
Route Of Administration : ORAL
Pack : 10

Drug Ingredient Information

NIMESULIDE-100MG+TIZANIDINE-2MG

NIMESULIDE

Information for patients
Drug Information Nimesulide is a relatively COX-2 selective, non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties. Its approved indications are the treatment of acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea in adolescents and adults above 12 years old. Due to concerns about the risk of hepatotoxicity, nimesulide has been withdrawn from market in many countries. Nimesulide is primarily indicated in conditions like Bursitis, Gynecological infections, Osteoarthritis, Rheumatoid arthritis, Tendinitis, Thrombophlebitis, Trauma, and can also be given in adjunctive therapy as an alternative drug of choice in Ent infections.
Drug Alert
Alert Nimesulide must be used with care among patients with a history of bleeding, with illnesses of the upper gastrointestinal tract and to subjects undergoing treatment with anticoagulants or drugs that inhibit platelet aggregation. The patients must be under direct medical supervision while taking substances with limited gastric tolerance at the same time. Since the drug is eliminated mainly through the kidneys, patient with the renal insufficiency must have a lower dosage depending on the glomerular filtration rate.
Before Consuming the Medicine
Avoid Drug Nimesulide must be used with care among patients with a history of bleeding, with illnesses of the upper gastrointestinal tract and to subjects undergoing treatment with anticoagulants or drugs that inhibit platelet aggregation. The patients must be under direct medical supervision while taking substances with limited gastric tolerance at the same time. Since the drug is eliminated mainly through the kidneys, patient with the renal insufficiency must have a lower dosage depending on the glomerular filtration rate. The product must not be administered to the patient with severe renal insufficiency. The product can cause water retention, therefore it must not be administered to the patient with reduced cardiac function. Patients whose activity require alertness must take the product with care in case they notice drowsiness or vertigo during therapy . Cases of visual disturbances when using other non-steroidal anti-inflammatory drugs have been reported, If eye problems appear, the treatment must be interrupted and an eye examination must be performed.
Drug Special Care Nimesulide is contraindicated in conditions like GI ulceration, GI hemorrhage.
Drug Drug Interactions No data regarding the interactions of Nimesulide was found.
Drug Pregnancy Interaction Women should use the drug with caution during lactation and it is contraindicated during pregnancy
Drug Breast feeding Interaction Women should use the drug with caution during lactation and it is contraindicated during pregnancy
Drug Machinery Interaction
Drug More Information
How to take the Medicine
Consumption Info
Drug quanitty Adult Dosage ( >12 years. ) 100.000 mg 100 (100) 12 hourly PO Increase upto 200mg bid. Paedriatic Dosage ( 20 Kg. ) No data regarding the Paediatric dosage details of Nimesulide is available. Neonatal Dosage ( 3 Kg. ) No data regarding the Neonatal dosage details of Nimesulide is available.
Drug Dose
Excess Drug Consumption
Forgot Drug Consumption
Stop Drug Consumption
Possible Side Effects
General Information
Common Drug Side Effects Like most drugs in NSAID category, nimesulide is known to be hepatotoxic (damaging to the liver) in rare but unpredictable cases and should be taken with care. The patient information leaflet informs that the use of nimesulide in children under the age of 12 is contraindicated. The drug has certain side effects, that can affect individuals in different ways. The following are some of the side effects, that are often associated with the drug: Diarrhoea Vomiting Skin rash Pruritis Dizziness Headache Bitterness in mouth Women should use the drug with caution during lactation and it is contraindicated during pregnancy.
Rare Drug Side Effects
Very Rare Drug Side Effects
Drug Side Effects Symptoms
How to Store the Medicine
How to Store the Medicine Stoe in a cool and dry place.

TIZANIDINE

Information for patients
Drug Information - Are allergic (hypersensitive) to tizanidine hydrochloride or any of the other ingredients in TIZANIDINE. - Have liver problems. - Are taking a medicine called fluvoxamine or ciprofloxacin. TIZANIDINE is not suitable for children or the elderly
Drug Alert
Alert - Are allergic (hypersensitive) to tizanidine hydrochloride or any of the other ingredients in TIZANIDINE. - Have liver problems. - Are taking a medicine called fluvoxamine or ciprofloxacin. TIZANIDINE is not suitable for children or the elderly
Before Consuming the Medicine
Avoid Drug - Are allergic (hypersensitive) to tizanidine hydrochloride or any of the other ingredients in TIZANIDINE. - Have liver problems. - Are taking a medicine called fluvoxamine or ciprofloxacin. TIZANIDINE is not suitable for children or the elderly
Drug Special Care - An intolerance to certain sugars (lactose and cellulose). - Kidney problems. If any of the above apply to you, you should speak to your doctor before taking this medicine.
Drug Drug Interactions Please tell your doctor or pharmacist if you are taking or have recently taken, any other medicines, including medicines obtained without a prescription. This is especially important if you are taking any of the following: • Theoralcontraceptivepill. • Antibiotics called norfloxacin, enoxacin. • Ticlopidinetothintheblood. • Cimetidineforstomachulcers. • Medicineswhichmaymakeyoudrowsye.g.sedatives. • Medicinesfor high blood pressure (e.g. water tablets or beta-blockers). • Medicinesforabnormal heart rhythms e.g. digoxin, amiodarone, mexiletine or propafenone. • Medicinesthatcouldaffecttheelectricalrhythmofyourheart(QTprolongation)
Drug Pregnancy Interaction TIZANIDINE is not recommended for use during pregnancy and breast-feeding. If you are pregnant, think you might be pregnant, or are breast-feeding tell your doctor or pharmacist before you take this medicine
Drug Breast feeding Interaction TIZANIDINE is not recommended for use during pregnancy and breast-feeding. If you are pregnant, think you might be pregnant, or are breast-feeding tell your doctor or pharmacist before you take this medicine
Drug Machinery Interaction TIZANIDINE can sometimes cause drowsiness or dizziness in some people. If you are affected you should not drive or operate machinery
Drug More Information Alcohol can sometimes increase the chance of you feeling drowsy while taking TIZANIDINE. You should not drink alcohol with Tizanidine as it may cause sedation, consult your doctor before taking alcohol with Tizanidine
How to take the Medicine
Consumption Info TIZANIDINE contains lactose and cellulose which are types of sugars. If you have been told you have an intolerance to some sugars contact your doctor before taking this medicine.
Drug quanitty Your doctor will usually start treatment with one 2 mg tablet once a day, but may instruct you to gradually increase the number of tablets you take and spread them out over the day. The exact dose will depend on your response to the tablets. The total dose should not exceed 36 mg.
Drug Dose Always take your medicine exactly as your doctor has told you. You should check with your doctor or pharmacist if you are not sure In patients with kidney disease the dose may be increased more slowly and you may need blood tests to check on your kidneys
Excess Drug Consumption If you take too much TIZANIDINE you should contact your doctor or go to the nearest hospital emergency department immediately. Take the packet and this leaflet with you so that the doctor will know what you have taken
Forgot Drug Consumption If you forget to take your dose in the morning you should take it as soon as you remember unless it is nearly time for your next dose. Do not take a double dose to make up for a forgotten one
Stop Drug Consumption The following side effects have been observed when patients stop taking TIZANIDINE suddenly after a long period of time, especially in patients on a high dose of TIZANIDINE or patients who take TIZANIDINE with drugs used to lower blood pressure: high blood pressure, increased heart rate (which may result in headache, blurred vision). Talk to your doctor before stopping treatment with TIZANIDINE
Possible Side Effects
General Information Like all medicines, TIZANIDINE can cause side effects, although not everyone gets them. You should tell your doctor immediately if you experience signs of liver damage such as dark urine or yellowing of the eyes or skin. Other side effects include: • Drowsiness,feelingtired,problemssleepingandweakmuscles. • Drymouth,feelingsickandstomachproblems. • Slowpulseorlowbloodpressure. • Mildhallucinations,dizzinessandlossofconsciousness. • Skinreactionssuchasitchingornettlerash. • Abnormallivertestsorinflammationoftheliver. If any of the side effects become serious or you notice any side effects which are not listed in this leaflet, please tell your doctor or pharmacist
Common Drug Side Effects
Rare Drug Side Effects
Very Rare Drug Side Effects
Drug Side Effects Symptoms
How to Store the Medicine
How to Store the Medicine Keep out of the reach and sight of children. Keep the tablets in the pack and do not use after the expiry date stated on the pack. There are no special precautions for storage Medicinesshouldnotbedisposedofviawastewaterorhouseholdwaste.Askyourpharmacisthowto dispose of medicines no longer required. These measures help protect the environment

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