Using Ofloxacin (an antibiotic) repeatedly without a clear diagnosis can cause rebound irritation. Since the redness and pain are shifting between your eyes, you may have viral conjunctivitis, an allergic reaction, or an inflammatory condition like uveitis, which antibiotics cannot cure. Please stop self-medicating and see an ophthalmologist immediately for a proper examination. They will determine the exact cause and prescribe targeted therapy, such as antiviral, steroid, or lubricating drops. Meanwhile, practice strict hygiene: avoid touching your eyes, wash your hands frequently, and use preservative-free artificial tears or cold compresses for temporary relief. Do not share towels or pillows to prevent spreading.

Ofloxacin is an antibiotic, which only treats bacterial infections. Since your primary symptoms are red and itchy eyes with no relief after three days, your condition is likely caused by an allergy (allergic conjunctivitis) or dry eyes, rather than a bacterial infection. I recommend stopping the Ofloxacin drops and consulting an eye doctor for a proper diagnosis. For immediate, safe relief from itching and redness, you can try over-the-counter antihistamine eye drops (like Ketotifen) and preservative-free artificial tears. Additionally, applying a cool compress over closed eyelids can help soothe the irritation. Avoid rubbing your eyes.