Olmesartan belongs to a group of medicines called angiotensin-II receptor antagonists. They lower blood pressure by relaxing the blood vessels. Olmesartan is used for the treatment of high blood pressure (also known as ‘hypertension’). High blood pressure can damage blood vessels in organs such as the heart, kidneys, brain and eyes. In some cases this may lead to a heart attack, heart or kidney failure, stroke or blindness. Usually high blood pressure has no symptoms. It is important to have your blood pressure checked to prevent damage occurring. High blood pressure can be controlled with medicines such as Olmesartan tablets. Your doctor has probably also recommended that you make some changes in your lifestyle to help lower your blood pressure (for example losing weight, giving up smoking, reducing the amount of alcohol you drink and reducing the amount of salt in your diet). Your doctor may also have urged you to take regular exercise, such as walking or swimming. It is important to follow this advice from your doctor.
||• if you are allergic (hypersensitive) to olmesartan medoxomil or to any other of the ingredients of Olmesartan
• if you are more than 3 months pregnant. (It is also better to avoid Olmesartan tablets in early pregnancy - see pregnancy section.)
• if you suffer from yellowing of the skin and eyes (jaundice) or problems with drainage of the bile from the gallbladder (biliary obstruction e.g. gallstones).
|Drug Special Care
||Before you take the tablets, tell your doctor if you have any of the following health problems:
• Kidney problems
• Liver disease
• Heart failure or problems with your heart valves or heart muscle
• Severe vomiting, diarrhoea, treatment with high doses of water tablets (diuretics) or if you are on a low salt diet
• Increased levels of potassium in your blood
• Problems with your adrenal glands.
As with any medicine which reduces blood pressure, an excessive drop in blood pressure in patients with blood flow disturbances of the heart
or brain could lead to a heart attack or stroke. Your doctor will therefore check your blood pressure carefully. You must tell your doctor if you think you are (or might become) pregnant. Olmesartan is not recommended in early pregnancy, and must not be taken if you are more than 3 months pregnant, as it may cause serious harm to your baby if used at that stage
|Drug Drug Interactions
||• Potassium supplements, a salt substitute which contains potassium, water tablets (diuretics) or heparin (for thinning the blood). Using these medicines at the same time as Olmesartan may raise the levels of potassium in your blood.
• Lithium (a medicine used to treat mood swings and some types of depression) used at the same time as Olmesartan may increase the toxicity of lithium. If you have to take lithium, your doctor will measure your lithium blood levels.
• Non-Steroidal Anti-Inflammatory (NSAIDs) medicines (medicines used to relieve pain, swelling and other symptoms of inflammation, including arthritis) used at the same time as Olmesartan may increase the risk of kidney failure and the effect of Olmesartan can be decreased by NSAIDs.
• Other blood pressure lowering medicines, as the effect of Olmesartan can be increased.
• Certain antacids (indigestion remedies), as the effect of Olmesartan can be slightly decreased.
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.
|Drug Pregnancy Interaction
||You must tell your doctor if you think you are (or might become) pregnant. Your doctor will normally advise you to stop taking Olmesartan
before you become pregnant or as soon as you know you are pregnant and will advise you to take another medicine instead of Olmesartan. Olmesartan is not recommended in early pregnancy, and must not be taken when more than 3 months pregnant, as it may cause serious harm to your baby if used after the third month of pregnancy.
|Drug Breast feeding Interaction
||Tell your doctor if you are breast-feeding or about to start breast-feeding. Olmesartan is not recommended for mothers who are breast-feeding, and your doctor may choose another treatment for you if you wish to breast-feed, especially if your baby is newborn, or was born prematurely. Ask your doctor or pharmacist for advice before taking any medicine.
|Drug Machinery Interaction
||It is unlikely that Olmesartan will affect your ability to drive or operate machinery. However, dizziness or fatigue can occasionally occur during the treatment of high blood pressure. If you notice such effects, do not drive or use machines until the symptoms wear off. Ask your doctor for advice.
|Drug More Information
||Taking Olmesartan with food and drink
Olmesartan can be taken with or without food. Swallow the tablets with a little water. If possible, take your daily dose at the same time each day, for example at breakfast time.
Children and adolescents (under 18)
Olmesartan is not recommended for children and adolescents under the age of 18.
If you are over 65 years of age and your doctor decides to increase your dose of olmesartan medoxomil to 40 mg daily, then you need to have your blood pressure regularly checked by your doctor to make sure that your blood pressure does not become too low.
As with other similar drugs the blood pressure lowering effect of Olmesartan is somewhat less in black patients.
|How to take the
||The usual starting dose is one 10 mg tablet once a day. However, if your blood pressure is not controlled, your doctor may decide to change your dose up to 20 or 40 mg once a day, or prescribe additional medicines. In patients with mild to moderate kidney disease, your dose will not be higher than 20 mg once a day.
||Always take Olmesartan exactly as your doctor has told you. You should check with your doctor or pharmacist if you are not sure.
The tablets can be taken with or without food. Swallow the tablets with a little water. If possible, take your daily dose at the same time each day, for example at breakfast time.
|Excess Drug Consumption
||If you take more tablets than you should or if a child accidentally swallows some, go to your doctor or nearest emergency department immediately and take your medicine pack with you.
|Forgot Drug Consumption
||If you forget a dose, take your normal dose on the following day as usual. Do not take any extra tablets to make up for the missed dose.
|Stop Drug Consumption
||It is important to continue to take Olmesartan unless your doctor tells you to stop. If you have any further questions on the use of this product, ask your doctor or pharmacist.
||Like all medicines, Olmesartan can cause side effects, although not everybody gets them. If they do occur, they are often mild and do not require treatment to be stopped. Although not many people may get them, the following two side effects can be serious:
On very rare occasions the following allergic reactions have been reported: Swelling of the face, mouth and/or larynx (voice box) together with itching and rash may occur during treatment with Olmesartan. If this happens
stop taking Olmesartan and contact your doctor immediately.
Rarely (but slightly more often in elderly patients) Olmesartan can cause the blood pressure to fall too low in susceptible individuals. This could cause severe light-headedness or fainting. If this occurs stop taking Olmesartan, contact your doctor immediately and lie down flat.
|Common Drug Side Effects
||Dizziness, nausea, indigestion, diarrhoea, stomach ache, gastroenteritis, tiredness, sore throat, runny or stuffy nose, bronchitis, flu-like symptoms, cough, pain in the chest, back, bones or joints, infection of the urinary tract, swelling of ankles, feet, legs, hands or arms, blood in the urine. Some changes in blood test results have also been seen and include the following: Increased fat levels (hypertriglyceridaemia), increased uric acid levels (hyperuricaemia), increases in tests of liver and muscle function.
|Rare Drug Side Effects
||Rarely, blood test results have shown increased potassium levels (hyperkalaemia).Vertigo, skin rash, angina (pain or uncomfortable feeling in the chest).
|Very Rare Drug Side Effects
||Headache, muscle cramps and muscular pain, impaired kidney function, kidney failure, weakness, lack of energy, feeling unwell, vomiting, itching, exanthema (skin eruption). compounds related to kidney function and reduced numbers of a type of blood cell, known as platelets (thrombocytopenia). If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist
|Drug Side Effects Symptoms
|How to Store the
|How to Store the Medicine
||Keep out of the reach and sight of children. This medicinal product does not require any special storage conditions. Do not use Olmesartan after the expiry date (“EXP”) which is stated on the box and on the blister strip. The expiry date refers to the last day of that month. Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.