PIOPOD GM 2MG TABLET

Manufacturer : TOR-TORRENT PHARMA LTD
Composition : GLIMEPIRIDE-2MG+METFORMIN-500MG+PIOGLITAZONE-15MG
Dose Form : TABLET
Description : PIOPOD GM 2MG TAB
Route Of Administration : ORAL
Pack : 10
Out of stock
SKU
PIO0082
₹126.40
Manufacturer : TOR-TORRENT PHARMA LTD
Composition : GLIMEPIRIDE-2MG+METFORMIN-500MG+PIOGLITAZONE-15MG
Dose Form : TABLET
Description : PIOPOD GM 2MG TAB
Route Of Administration : ORAL
Pack : 10

Drug Ingredient Information

GLIMEPIRIDE-2MG+METFORMIN-500MG+PIOGLITAZONE-15MG

GLIMEPIRIDE

Information for patients
Drug Information Glimepiride is a medicine taken by mouth to help lower blood sugar. It belongs to a group of medicines called sulfonylureas. Glimepiride works by increasing the amount of insulin released from your pancreas. The insulin then lowers your blood sugar levels. What Glimepiride is used for: • Glimepiride is used to treat a certain form of diabetes (type 2 diabetes mellitus) when diet, physical exercise and weight reduction alone have not been able to control your blood sugar levels
Drug Alert
Alert You are allergic (hypersensitive) to: Glimepiride or other sulfonylureas (medicines used to lower your blood sugar such as glibenclamide) or sulfonamides (medicines for bacterial infections such as sulfamethoxazole) or any of the other ingredients of Glimepiride (listed in Section 6 What Glimepiride contains) • You have insulin dependent diabetes (type 1 diabetes mellitus)
Before Consuming the Medicine
Avoid Drug You are allergic (hypersensitive) to: Glimepiride or other sulfonylureas (medicines used to lower your blood sugar such as glibenclamide) or sulfonamides (medicines for bacterial infections such as sulfamethoxazole) or any of the other ingredients of Glimepiride (listed in Section 6 What Glimepiride contains) • You have insulin dependent diabetes (type 1 diabetes mellitus) • You have diabetic ketoacidosis (a complication of diabetes when your acid level is raised in your body and you may have some of the following signs: fatigue, feeling sick (nausea), frequent urination and muscular stiffness) • You are in a diabetic coma • You have severe kidney disease • You have a severe liver disease Do not take this medicine if any of the above apply to you. If you are not sure, talk to your doctor or pharmacist before taking Glimepiride
Drug Special Care Check with your doctor or pharmacist before taking your medicine if: • You are recovering from an injury, operation, infections with fever, or from other forms of stress, inform your doctor as temporary change of treatment may be necessary • You have a severe liver or kidney disorder If you are not sure if any of these apply to you, talk to your doctor or pharmacist before taking Glimepiride. Lowering of the haemoglobin level and breakdown of red blood cells (haemolytic anemia) can occur in patients missing the enzyme glucose-6-phosphate dehydrogenase. The information available on the use of Glimepiride in people under 18 years of age is limited. Therefore, its use in these patients is not recommende
Drug Drug Interactions Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription. Your doctor may wish to change your dose of Glimepiride if you are taking other medicines, which may weaken or strengthen the effect of Glimepiride on the level of sugar in your blood. The following medicines can increase the blood sugar lowering effect of Glimepiride. This can lead to a risk of hypoglycaemia (low blood sugar): • Other medicines to treat diabetes mellitus (such as insulin or metformin) • Medicines to treat pain and inflammation (phenylbutazone, azopropazone, oxyphenbutazone, aspirin-like medicines) • Medicines to treat urinary infections (such as some long acting sulfonamides) • Medicines to treat bacterial and fungal infections (tetracyclines, chloramphenicol, fluconazole, miconazole, quinolones, clarithromycin) • Medicines to inhibit blood clotting (coumarin derivatives such as warfarin) • Medicines supporting muscle build up (anabolics) • Medicines used for male sex hormone replacement therapy • Medicines to treat depression (fluoxetine, MAO- inhibitors) • Medicines lowering high cholesterol level (fibrates) • Medicines lowering high blood pressure (ACE inhibitors) • Medicines called anti-arrhythmic agents used to control abnormal heart beat (disopyramide) • Medicines to treat gout (allopurinol, probenecid, sulfinpyrazone) • Medicines to treat cancer (cyclophosphamide, ifosfamide, trofosfamide) • Medicines used to reduce weight (fenfluramine) • Medicines to increase circulation when given in a high dose intravenous infusion (pentoxifylline) • Medicines to treat nasal allergies such as hay fever (tritoqualine) • Medicines called sympatholytics to treat high blood pressure, heart failure, or prostate symptoms The following medicines may decrease the blood sugar lowering effect of Glimepiride. This can lead to a risk of hyperglycaemia (high blood sugar level): • Medicines containing female sex hormones (oestrogens, progestogens) • Medicines to treat high blood pressure called thiazide diuretics (water tablets) • Medicines used to stimulate the thyroid gland (such as levothyroxine) • Medicines to treat allergies and inflammation (glucocorticoids) • Medicines to treat severe mental disorders (chlorpromazine and other phenothiazine derivatives) • Medicines used to raise heart beat, to treat asthma or nasal congestion, coughs and colds, used to reduce weight, or used in life-threatening emergencies (adrenaline and sympathomimetics) • Medicines to treat high cholesterol level (nicotinic acid) • Medicines to treat constipation when they are used long term (laxatives) • Medicines to treat fits (phenytoin) • Medicines to treat nervousness and sleep problems (barbiturates) • Medicines to treat increased pressure in the eye (azetazolamide) • Medicines to treat high blood pressure or lowering blood sugar (diazoxide) • Medicines to treat infections, tuberculosis (rifampicine) • Medicines to treat severe low blood sugar levels (glucagon) The following medicines can increase or decrease the blood sugar lowering effect of Glimepiride: • Medicines to treat stomach ulcers (called H2 antagonists) • Medicines to treat high blood pressure or heart failure such as beta-blockers, clonidine, guanethidine and reserpine. These can also hide the signs of hypoglycaemia, so special care is needed when taking these medicines Glimepiride may either increase or weaken the effects of the following medicines: • Medicines inhibiting blood clotting (coumarin derivatives such as warfarin)
Drug Pregnancy Interaction Glimepiride should not be taken during pregnancy. Tell your doctor if you are, you think you might be or are planning to become pregnant
Drug Breast feeding Interaction Glimepiride may pass into breast milk. Glimepiride should not be taken during breast feeeding. Ask your doctor or pharmacist for advice before taking any medicine
Drug Machinery Interaction your blood sugar is lowered (hypoglycaemia), or raised (hyperglycaemia) or if you develop visual problems as a result of such conditions. Bear in mind that you could endanger yourself or others (e.g. when driving a car or using machines). Please ask your doctor whether you can drive a car if you: • have frequent episodes of hypoglycaemia, • have fewer or no warning signals of hypoglycaemia
Drug More Information Important information about hypoglycaemia (low blood sugar) When you take Glimepiride, you may get hypoglycaemia (low blood sugar). Please see below for additional information about hypoglycaemia, its signs and treatment. Following factors could increase the risk of you getting hypoglycaemia: • Undernourishment, irregular meal time, missed or delayed meal or period of fasting • Changes to your diet • Taking more Glimepiride than needed • Having kidneys that do not work properly • Having severe liver disease • If you suffer from particular hormone-induced disorders (disorders of the thyroid glands, of the pituitary gland or adrenal cortex) • Drinking alcohol (especially when you skip a meal) • Taking certain other medicines (See Taking other medicines below) • If you increase the amount of exercise you do and you don''t eat enough food or eat food containing less carbohydrate than usual. Signs of hypoglycaemia include: • Hunger pangs, headache, nausea, vomiting, sluggishness, sleepiness, problems sleeping, restlessness, aggression, problems with concentration, reduced alertness and reaction time, depression, confusion, problems with your speech and sight, slurred speech, shakiness, partial paralysis, dizziness, helplessness • The following signs may also occur: sweating, clammy skin, anxiety, fast or increased heart beat, high blood pressure, awareness of your heart beat, sudden strong pain in the breast that may radiate into neighbouring areas (angina pectoris and cardiac arrhythmias) If blood sugar levels continue to drop you may suffer from considerable confusion (delirium), develop fits, lose self control, breathing may be shallow and your heart beat slowed down, you may fall into unconsciousness. The clinical picture of a severe reduced blood sugar level may resemble that of a stroke. Treating hypoglycaemia: In most cases the signs of reduced blood sugar vanish very quickly when you consume some form of sugar, e.g. sugar cubes, sweet juice, sweetened tea. You should therefore always take some form of sugar with you (e.g. sugar cubes). Remember that artificial sweeteners are not effective. Please contact your doctor or go to the hospital if taking sugar does not help or if the symptoms recur. Laboratory Tests The level of sugar in your blood or urine should be checked regularly. Your doctor may also take blood tests to monitor your blood cell levels and liver function.
How to take the Medicine
Consumption Info Glimepiride contains lactose. If you have been told by your doctor that you cannot tolerate some sugars, contact your doctor before taking this medicinal product. Alcohol intake may increase or decrease the blood sugar lowering action of Glimepiride in an unpredictable way.
Drug quanitty The dose of Glimepiride depends on your needs, condition and results of blood and urine sugar tests and is determined by your doctor. Do not take more tablets than your doctor has prescribed. • The usual starting dose is one Glimepiride 1 mg tablet once a day • If necessary, your doctor may increase the dose after each 1 - 2 weeks of treatment • The maximum recommended dose is 6 mg Glimepiride per day • A combination therapy of glimepiride plus metformin or of glimepiride plus insulin may be started. In such a case your doctor will determine the proper doses of glimepiride, metformin or insulin individually for you • Your dose of Glimepiride may need to be adjusted if you change weight, change your lifestyle, or if you are under a lot of stress. Please speak to your doctor if any of these situations apply to you • If you feel the effect of your medicine is too weak or too strong do not change the dose yourself, but ask your doctor
Drug Dose • Take this medicine by mouth, just before or with the first main meal of the day (usually breakfast). If you do not have breakfast you should take the product on schedule as prescribed by your doctor. It is important not to leave out any meal when you are on Glimepiride • Swallow the tablets whole with at least half glass of water. Do not crush or chew the tablets
Excess Drug Consumption If you happen to have taken too much Glimepiride or an additional dose there is a danger of hypoglycaemia (signs of hypoglycaemia see Section 2 - Take special care with Glimepiride) and therefore you should instantly consume enough sugar (e.g. a small bar of sugar cubes, sweet juice, sweetened tea) and inform a doctor immediately. When treating hypoglycaemia due to accidental intake in children, the quantity of sugar given must be carefully controlled to avoid the possibility of producing dangerous hyperglycaemia. Persons in a state of unconsciousness must not be given food or drink. Since the state of hypoglycaemia may last for some time it is very important that the patient is carefully monitored until there is no more danger. Admission into hospital may be necessary, also as a measure of precaution. Show the doctor the package or remaining tablets, so the doctor knows what has been taken. Severe cases of hypoglycaemia accompanied by loss of consciousness and coma are cases of medical emergency requiring immediate medical treatment and admission into hospital. It may be helpful to tell your family and friends to call a doctor immediately if this happens to you
Forgot Drug Consumption If you forget to take a dose, do not take a double dose to make up for forgotten doses
Stop Drug Consumption If you interrupt or stop the treatment you should be aware that the desired blood sugar lowering effect is not achieved or that the disease will get worse again. Keep taking Glimepiride until your doctor tells you to stop.
Possible Side Effects
General Information • Allergic reactions (including inflammation of blood vessels, often with skin rash) which may develop into serious reactions with difficulty in breathing, fall in blood pressure and sometimes progressing to shock • Abnormal liver function including yellowing of the skin and eyes (jaundice), problems with the bile flow (cholestasis), inflammation of the liver (hepatitis) or liver failure • Allergy (hypersensitivity) of the skin such as itching, rash, hives and increased sensitivity to sun. Some mild allergic reactions may develop into serious reactions • Severe hypoglycaemia including loss of consciousness, seizures or coma Some patients experienced the following side effects whilst taking
Common Drug Side Effects • Allergy (hypersensitivity) of the skin may occur such as itching, rash, hives and increased sensitivity to sun. Some mild allergic reactions may develop into serious reactions with swallowing or breathing problems, swelling of your lips, throat or tongue. Therefore in the event of one of these side effects, tell your doctor immediately • Allergic reactions with sulfonylureas, sulfonamides, or related drugs may occur • Problems with your sight may occur when beginning treatment with Glimepiride. This is due to changes in blood sugar levels and should soon improve • Increased liver enzymes If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist
Rare Drug Side Effects • Lower blood sugar than normal (hypoglycaemia) (See Section 2 - Take special care with Glimepiride) • Decrease in the number of blood cells: • Blood platelets (which increases risk of bleeding or bruising) • White blood cells (which makes infections more likely) • Red blood cells (which can make the skin pale and cause weakness or breathlessness) These problems generally get better after you stop taking Glimepiride
Very Rare Drug Side Effects • Allergic reactions (including inflammation of blood vessels, often with skin rash) which may develop into serious reactions with difficulty in breathing, fall in blood pressure and sometimes progressing to shock. If you experience any of these symptoms, tell your doctor immediately • Abnormal liver function including yellowing of the skin and eyes (jaundice), impairment of the bile flow (cholestasis), inflammation of the liver (hepatitis) or liver failure. If you experience any of these symptoms, tell your doctor immediately • Feeling or being sick, diarrhoea, feeling full or bloated, and abdominal pain • Decrease in the amount of sodium level in your blood (shown by blood tests)
Drug Side Effects Symptoms
How to Store the Medicine
How to Store the Medicine Keep out of the reach and sight of children. Do not use Glimepiride after the expiry date which is stated after ‘EXP’ on the blister and carton. The expiry date refers to the last day of that month. Glimepiride 1 mg, 2 mg, 3 mg, and 4 mg tablets: do not store above 30°C. Store in the original package in order to protect from moisture Do not use Glimepiride if you notice visible signs of deterioration. Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.

METFORMIN

Information for patients
Drug Information Metformin is used alone or with other medications, including insulin, to treat type 2 diabetes (condition in which the body does not use insulin normally and, therefore, cannot control the amount of sugar in the blood). Metformin helps to control the amount of glucose (sugar) in your blood. It decreases the amount of glucose you absorb from your food and the amount of glucose made by your liver. Metformin also increases your body's response to insulin, a natural substance that controls the amount of glucose in the blood. Metformin is not used to treat type 1 diabetes (condition in which the body does not produce insulin and therefore cannot control the amount of sugar in the blood).
Drug Alert
Alert no data available
Before Consuming the Medicine
Avoid Drug Tell your doctor if you regularly drink alcohol or sometimes drink large amounts of alcohol in a short time (binge drinking). Drinking alcohol increases your risk of developing lactic acidosis or may cause a decrease in blood sugar. Ask your doctor how much alcohol is safe to drink while you are taking metformin.
Drug Special Care Before taking metformin, tell your doctor and pharmacist if you are allergic to metformin or any other medications. tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking. Be sure to mention the medications listed in the IMPORTANT WARNING section and any of the following: amiloride (Midamor, Moduretic); antihistamines; beta-blockers such as atenolol (Tenormin), labetalol (Normodyne), metoprolol (Lopressor, Toprol XL), nadolol (Corgard), and propranolol (Inderal); calcium channel blockers such as amlodipine (Norvasc), diltiazem (Cardizem, Dilacor, Tiazac, others), felodipine (Lexxel, Plendil), isradipine (DynaCirc), nicardipine (Cardene), nifedipine (Adalat, Procardia), nimodipine (Nimotop), nisoldipine (Sular), and verapamil (Calan, Isoptin, Verelan); cimetidine (Tagamet); digoxin (Lanoxin, Lanoxicaps); furosemide (Lasix); hormone replacement therapy; insulin or other medications for diabetes; isoniazid (INH, Nydrazid); medications for asthma and colds; medications for mental illness and nausea such as fluphenazine (Prolixin), mesoridazine (Serentil), perphenazine (Trilafon), prochlorperazine (Compazine), promethazine (Phenergan), thioridazine (Mellaril), thiothixene (Navane), trifluoperazine (Stelazine), and triflupromazine (Vesprin); medications for thyroid disease; morphine (MS Contin, Roxanol, others); nicotinic acid; oral contraceptives ('birth control pills'); oral steroids such as dexamethasone (Decadron, Dexone), methylprednisolone (Medrol), and prednisone (Deltasone); phenytoin (Dilantin, Phenytek); procainamide (Procanbid); quinidine (Quinidex); quinine; ranitidine (Zantac); triamterene (Dyazide, Maxzide, others); or trimethoprim (Proloprim, Trimpex). Your doctor may need to change the doses of your medications or monitor you carefully for side effects. tell your doctor if you have or have ever had any medical condition, especially those mentioned in the IMPORTANT WARNING section. tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking metformin, call your doctor. if you are using the extended-release tablets, you should know that sometimes the tablet shell may appear in your stool. If this occurs, it is not harmful and will not affect the way the medication works. tell your doctor if you eat less or exercise more than usual. This can affect your blood sugar. Your doctor will give you instructions if this happens.
Drug Drug Interactions acyclovir (Zovirax); acetaminophen (Tylenol); aminoglycoside antibiotics such as amikacin (Amikin), gentamicin (Garamycin), Kanamycin (Kantrex), Neomycin (Neo-Fradin, Neo-Rx), netilmicin (Netromycin), paromomycin (Humatin), streptomycin and tobramycin (Nebcin, Tobi); amphotericin B (Abelcet, Amphocin, others); angiotensin converting enzyme (ACE) inhibitors such as benazepril (Lotensin), captopril (Capoten), enalapril (Vasotec), fosinopril (Monopril), lisinopril (Prinvil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), ramipril (Altace), and trandolapril (Mavik); aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Advil, Motrin) and naproxen (Aleve, Naprosyn); cancer chemotherapy medications; cyclosporine (Sandimmune, Neoral); dapsone (Avlosulfon); diuretics (water pills); foscarnet (Foscavir); gold compounds such as auranofin (Ridaura), aurothioglucose (Aurolate, Solganol), and gold sodium thiomalate (Myochrysine); hydralazine (Hydra-Zide); lithium (Eskalith, Lithobid); medications to treat human immunodeficiency virus (HIV) or acquired immunodeficiency syndrome (AIDS); methicillin (Staphcillin); nitrates; penicillin and sulfa antibiotics; penicillamine (Cuprimine, Depen); primaquine; propranolol (Inderal); rifampin (Rifadin, Rimactane); tacrolimus (Prograf); vancomycin (Vancocin); or if you have ever taken the Chinese weight-loss herb Aristolochia.
Drug Pregnancy Interaction no data available
Drug Breast feeding Interaction no data available
Drug Machinery Interaction no data available
Drug More Information In addition to describing the cardiovascular risks, the drug labels have been revised to state that rosiglitazone and rosiglitazone-containing medicines should only be used: In patients already being treated with these medicines In patients whose blood sugar cannot be controlled with other anti-diabetic medicines and who, after consulting with their healthcare professional, do not wish to use pioglitazone-containing medicines
How to take the Medicine
Consumption Info If you are having surgery, including dental surgery, any x-ray procedure in which dye is injected, or any major medical procedure, tell the doctor that you are taking metformin. You may need to stop taking metformin before the procedure and wait 48 hours to restart treatment. Your doctor will tell you exactly when you should stop taking metformin and when you should start taking it again.
Drug quanitty no data available
Drug Dose Metformin comes as a liquid, a tablet and an extended-release (long-acting) tablet to take by mouth. The liquid is usually taken with meals one or two times a day. The regular tablet is usually taken with meals two or three times a day. The extended-release tablet is usually taken once daily with the evening meal. To help you remember to take metformin, take it around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take metformin exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Swallow metformin extended-release tablets whole; do not split, chew, or crush them. Your doctor may start you on a low dose of metformin and gradually increase your dose not more often than once every 1 to 2 weeks. You will need to monitor your blood sugar carefully so your doctor will be able to tell how well metformin is working. Metformin controls diabetes but does not cure it. Continue to take metformin even if you feel well. Do not stop taking metformin without talking to your doctor.
Excess Drug Consumption In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911. Symptoms of overdose may include: extreme tiredness weakness discomfort vomiting nausea stomach pain decreased appetite deep, rapid breathing shortness of breath dizziness lightheadedness abnormally fast or slow heartbeat flushing of the skin muscle pain feeling cold
Forgot Drug Consumption Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
Stop Drug Consumption Do not stop the drug untill your doctor says you to do so.
Possible Side Effects
General Information extreme tiredness, weakness, or discomfort; nausea; vomiting; stomach pain; decreased appetite; deep and rapid breathing or shortness of breath; dizziness; lightheadedness; fast or slow heartbeat; flushing of the skin; muscle pain; or feeling cold.
Common Drug Side Effects Metformin may rarely cause a serious, life-threatening condition called lactic acidosis. Tell your doctor if you have or have ever had a heart attack; stroke; high blood pressure; diabetic ketoacidosis (blood sugar that is high enough to cause severe symptoms and requires emergency medical treatment) or coma; surgery to remove part of your small intestine; anemia (not enough red blood cells), or heart, kidney, lung, or liver disease.
Rare Drug Side Effects no data available
Very Rare Drug Side Effects no data available
Drug Side Effects Symptoms This medication may cause changes in your blood sugar. You should know the symptoms of low and high blood sugar and what to do if you have these symptoms. You may experience hypoglycemia (low blood sugar) while you are taking this medication. Your doctor will tell you what you should do if you develop hypoglycemia. He or she may tell you to check your blood sugar, eat or drink a food or beverage that contains sugar, such as hard candy or fruit juice, or get medical care. Follow these directions carefully if you have any of the following symptoms of hypoglycemia: shakiness dizziness or lightheadedness sweating nervousness or irritability sudden changes in behavior or mood headache numbness or tingling around the mouth weakness pale skin hunger clumsy or jerky movements If hypoglycemia is not treated, severe symptoms may develop. Be sure that your family, friends, and other people who spend time with you know that if you have any of the following symptoms, they should get medical treatment for you immediately: confusion seizures loss of consciousness Call your doctor immediately if you have any of the following symptoms of hyperglycemia (high blood sugar): extreme thirst frequent urination extreme hunger weakness blurred vision If high blood sugar is not treated, a serious, life-threatening condition called diabetic ketoacidosis could develop. Call your doctor immediately if you have any of these symptoms: dry mouth nausea and vomiting shortness of breath breath that smells fruity decreased consciousness Metformin may cause side effects. Tell your doctor if any of these symptoms are severe, do not go away, go away and come back, or do not begin for some time after you begin taking metformin: diarrhea bloating stomach pain gas constipation unpleasant metallic taste in mouth heartburn headache sneezing cough runny nose flushing of the skin nail changes muscle pain Some side effects can be serious. The following symptoms are uncommon, but if you experience any of them or those listed in the IMPORTANT WARNING section, call your doctor immediately: chest pain rash Some female laboratory animals given high doses of metformin developed non-cancerous polyps (abnormal growths of tissue) in the uterus (womb). It is not known if metformin increases the risk of polyps in humans. Talk to your doctor about the risks of taking this medication. Metformin may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
How to Store the Medicine
How to Store the Medicine Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from light excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

PIOGLITAZONE

Information for patients
Drug Information PIOGLITAZONE is a tablet that is used to improve the action of the body?s naturally produced insulin. It is used in the management of type 2 diabetes not controlled by diet. It helps to control the level of glucose in your blood when you have type 2 diabetes. This is the „adult onset? type of diabetes and is controlled by diet, certain oral medications and occasionally insulin. This medicine is available as pioglitazone hydrochloride and belongs to a group of medicines called glitazones. Glitazones decrease insulin resistance. Ask your doctor if you have any questions about why this medicine has been prescribed for you. Your doctor may have prescribed it for another reason. PIOGLITAZONE can be used alone (when diet and exercise is not enough to treat your diabetes) or together with other anti-diabetic medicines. This medicine is available only with a doctor?s prescription. The use of PIOGLITAZONE has not been studied in children.
Drug Alert
Alert no data available
Before Consuming the Medicine
Avoid Drug Do not take PIOGLITAZONE if you have: heart failure requiring treatment. Talk to your doctor if you have heart failure type 1 diabetes or diabetic ketoacidosis (often caused by very high blood glucose levels) an allergy to any medicine containing pioglitazone hydrochloride or any of the ingredients listed in the contents. Some of the symptoms of an allergic reaction may include shortness of breath, wheezing or difficulty breathing; swelling of the face, lips, tongue or other parts of the body; rash, itching or hives on the skin. Do not take this medicine after the date printed on the pack or if the packaging is torn or shows signs of tampering. If it has expired or is damaged, return it to your pharmacist for disposal. If you are not sure whether you should start taking this medicine, talk to your doctor.
Drug Special Care Before you start to take it • Tell your doctor if you have allergies to any other medicines, foods, preservatives or dyes. • Tell your doctor if you have or have had any of the following medical conditions: • heart disease with shortness of breath after minimal physical activity • heart disease with severe symptoms at rest • swelling of hands, ankles or feet • problems with your liver • problems with your kidneys that requires dialysis. PIOGLITAZONE is not recommended for use if you are on dialysis • some women who do not have monthly periods and have not been through menopause may restart their periods when taking PIOGLITAZONE. These women may be at increased risk of pregnancy • bone fractures, usually in the hand, upper arm or foot, have been seen in some women when taking PIOGLITAZONE. Talk to your doctor for advice on how to keep your bones healthy. • Tell your doctor if you are pregnant or plan to become pregnant or are breast-feeding.Things you must do It is important that you remember to take PIOGLITAZONE daily and at the dose prescribed by your doctor. Tell any other doctors, dentists and pharmacists who treat you that you are taking PIOGLITAZONE. If you are about to be started on any new medicine, remind your doctor and pharmacist that you are taking PIOGLITAZONE. If you are going to have surgery, tell the surgeon or anaesthetist that you are taking this medicine. It may affect other medicines used during surgery. If you are about to have any blood tests, tell your doctor that you are taking this medicine. It may interfere with the results of some tests. Keep all of your doctor’s appointments so that your progress can be checked. Your doctor may do some tests from time to time to make sure the medicine is working and to prevent unwanted side effects. Tell your doctor if you have gained weight since taking PIOGLITAZONE. Weight gain can be associated with improved blood sugar control however; it may also be a symptom of heart failure. Things you must not do Do not take PIOGLITAZONE to treat any other complaints unless your doctor tells you to. Do not give your medicine to anyone else, even if their symptoms seem similar to yours or they have the same condition as you.
Drug Drug Interactions Tell your doctor if you are using another medicine for diabetes. PIOGLITAZONE can enhance the action of other medicines. You may be at risk of low blood sugar (hypoglycaemia). If this happens, your doctor may need to adjust the dose of your other medicines. Tell your doctor if you suffer from lactose intolerance (because PIOGLITAZONE tablets contain lactose). If you have not told your doctor about any of the above, tell him/her before you start taking PIOGLITAZONE. Taking other medicines Tell your doctor or pharmacist if you are taking any other medicines, including any that you get without a prescription from your pharmacy, supermarket or health food shop. Some medicines and PIOGLITAZONE may interfere with each other. These include: chlorpropamide gemfibrozil glibenclamide gliclazide insulin metformin oral contraceptives rifampicin tolbutamide These medicines may be affected by PIOGLITAZONE or may affect how well it works. You may need different amounts of your medicines, or you may need to take different medicines. Your doctor or pharmacist has more information on medicines to be careful with or to avoid while taking this medicine.
Drug Pregnancy Interaction It is not recommended for use during pregnancy. If there is a need to consider PIOGLITAZONE during your pregnancy, your doctor will discuss with you the benefits and risks of taking PIOGLITAZONE.
Drug Breast feeding Interaction It is recommended that you do not breast-feed while taking PIOGLITAZONE, as it is not known whether this drug passes into breast milk.
Drug Machinery Interaction PIOGLITAZONE alone is unlikely to affect your ability to drive or operate machinery. However, be careful to avoid hypoglycaemia whilst driving or operating machinery if using PIOGLITAZONE combination with other diabetes medicines.
Drug More Information no data available
How to take the Medicine
Consumption Info Follow all directions given to you by your doctor or pharmacist carefully. They may differ from the information contained in this leaflet. If you do not understand the instructions on the carton, ask your doctor or pharmacist for help.
Drug quanitty Your doctor will tell you how many PIOGLITAZONE tablets you should take. The dose your doctor will prescribe for you will usually be in the range of 15 mg to 45 mg per day. PIOGLITAZONE tablets should be taken once a day as advised by your doctor. Your doctor may increase or decrease your dose in order to find the appropriate dose for your condition.
Drug Dose PIOGLITAZONE tablets should be swallowed whole with a glass of water. When to take it Take your medicine at about the same time each day. Taking it at the same time each day will have the best effect. It will also help you remember when to take it. It does not matter if you take this medicine before or after food. How long to take it Continue taking your medicine for as long as your doctor tells you. This medicine helps to control your condition, but does not cure it. It is important to keep taking your medicine even if you feel well.
Excess Drug Consumption Immediately telephone your doctor or the Poisons Information Centre or go to Accident and Emergency at the nearest hospital, if you think that you or anyone else may have taken too much PIOGLITAZONE. Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention.
Forgot Drug Consumption If it is almost time for your next dose, skip the dose you missed and take your next dose when you are meant to. Otherwise, take it as soon as you remember, and then go back to taking your medicine as you would normally. Do NOT take a double dose to make up for the dose that you missed. If you are not sure what to do, ask your doctor or pharmacist. If you have trouble remembering to take your medicine, ask your pharmacist for some hints.
Stop Drug Consumption Do not stop taking your medicine or lower the dosage without checking with your doctor. If you stop taking it suddenly, your condition may worsen or you may have unwanted side effects.
Possible Side Effects
General Information Tell your doctor or pharmacist as soon as possible if you experience any undesirable effect or feel unwell while you are taking PIOGLITAZONE. This medicine helps most people with type 2 diabetes not controlled by diet, but it may have unwanted side effects in some people. All medicines can have side effects. Sometimes they are serious, most of the time they are not. You may need medical attention if you get some of the side effects. Some side effects may be related to the dose of PIOGLITAZONE. Accordingly, it is important that you tell your doctor as soon as possible about any unwanted effects. Your doctor may then decide to adjust the dose of PIOGLITAZONE you are taking. Do not be alarmed by the following list of side effects. You may not experience any of them. Ask your doctor or pharmacist to answer any questions you may have.
Common Drug Side Effects A few patients have experienced the following side effects whilst taking PIOGLITAZONE: a small increase in weight low blood sugar levels (hypoglycaemia). This occurs more often when PIOGLITAZONE is taken with a sulfonylurea or insulin heart failure which may show as localised swelling of the ankles, feet and hands (oedema) and/or fluid in the lungs (pulmonary oedema). This has been reported in clinical trials mainly in patients who are taking PIOGLITAZONE in combination with insulin increased risk of fracture in women macular oedema (an eye disorder that can affect vision) altered or impaired liver function.
Rare Drug Side Effects dark urine or pale stools, yellowing of the skin or eyes, severe cramps of the stomach, nausea or vomiting, loss of weight, tiredness shortness of breath when at rest or after minimal physical activity with swelling of legs, feet and hands, rapid increase in weight The above list includes serious side effects, which may require medical attention. Serious side effects are rare.
Very Rare Drug Side Effects no data available
Drug Side Effects Symptoms weight gain signs of hypoglycaemia which may include weakness, trembling or shaking, sweating, light-headedness, headache, dizziness, lack of concentration, tearfulness or crying, irritability, hunger, numbness around the lips and fingers eye problems including blurred or double vision.
How to Store the Medicine
How to Store the Medicine Storage Keep your tablets in the aluminium blister pack until it is time to take them. Keep your tablets in a cool, dry place where the temperature stays below 30 degree celcius. Do not store PIOGLITAZONE or any other medicine in the bathroom or near a sink. Do not leave it on a window sill or in the car. Heat and dampness can destroy some medicines. Keep it where children cannot reach it. A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines. Disposal If your doctor tells you to stop taking PIOGLITAZONE or the expiry date has passed, ask your pharmacist what to do with any medicine that is left over.

Substitute Drugs

BEPRIDE FORTE TAB70
COFORMIN P2 TAB72.8
DEBISTAL GM TAB69.4
DIAGLIM MP2 TAB94
ENDOGLIM MP2 TAB89
EUGLIM-MP 2 TAB78.6
FORDIA PG 1MG TAB55
FORDIA PG 2MG TAB65
FORMIN PGL 2 TAB69.5
GEMER P2 TAB106
GEMINOR MP 2MG TAB98.8
GIVOV PM 2 TAB80
GLAMOR PM TAB67.6
GLISEN PM 2MG TAB103.5
GLIMESTAR PM 2MG TAB86.4
GLIMY MP 2 TAB95
GLIMSER-P2 TAB94.5
GLISTA PM 2MG TAB82.8
GLIMFIRST -MP 2 TAB80
GLIMIPRIME MP 2MG TAB72
GLIMISON PM 2 TAB42
GLIMISON-MP 2MG TAB28
GLITARAY MP 2 TAB80
GLISS-MP2 TAB 10'S72
GLUCUT-2 GMP TAB72.6
GLYCIPHAGE PG 2MG TAB83
GLYCIFIT TRIO G2 TAB93.6
GLYCICHEK-MP2 TAB72
GMP 2MG TAB47.3
GPM SR 2 TAB65
GPM 2 MG TAB83.5
HILMET GMP2 TAB79
INSTAMET PG2 TAB99.3
K-PIO-GM 2 MG TAB50
MATCE PG2 TAB (1X10)99.2
METSURGE GP2 TAB47
MOFIN PG-2 TAB89.9
OZOMET PG2 TAB20
PIOPOD GM 2MG TAB115
PIOMED MG 2 TAB92
PIOCON-GM2 TAB61.5
PIOPLUS 2MG TAB72
PIONEER GM2 TAB69
PIOBIT-GM 2 TAB65.9
PMG 2 MG TAB72.9
RIOMET TRIO 2 TAB108.5
SECRIN P2 TAB99
SUGAMET-GP2 TAB70.5
TIMER P-2 TAB72.5
TRIBET 2 MG TAB103.5
TRIGLIMIPREX 2MG TAB83
TRIPRIDE -2 TAB128
TRIOPIL-2MG TAB83
TRIGPM 2MG TAB96
TRIGLIMISAVE 2MG TAB85.8
TRIGLAZ FORTE CAP81.5
TRIGEM 2 MG80
TRILIFE-2MG TAB80
TRIDART-2MG TAB72.8
TRIXER 2 MG TAB121
TRIGLIMICURE 2MG TAB82
TRIBLEND 2 MG TAB68
TRIGLI LS 2 MG TAB42
TRIAPRIGLIM 2 TAB96
VIPRIDE-PM2 TAB72.8
ZETAGLIM MP2 TAB72
ZIGLIM PLUS 2MG TAB58
ZORYL MP 2 MG TAB166.05
3D-OHA TAB95.5
ADGLIM MP2 TAB73
ALNAMET 2GP TAB72.8
AMARYL MP2 MG TAB125.3
AMETO GP2 TAB82
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