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Dose Form : TABLET
Description : PLACIDA PLUS TAB
Route Of Administration : ORAL
Pack : 10

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Drug Ingredient Information



Information for patients
Drug Information Etizolam is a type of hypnotics. Etizolam belongs to category of hypnotics and sedatives drugs. Etizolam is athienodiazepine drug which is a benzodiazepine analog. The etizolam molecule differs from most other benzodiazepines in that the benzene ring has been replaced by a thiophene ring. It possesses amnesic, anxiolytic, anti convulsion, hypnotic, sedative and skeletal muscle relaxant properties. Myasthenia gravis, acute angle closure glaucoma, pregnancy, breast feeding, hypersensitivity, serve respiratory failure or hepatic impairment. Anxiety, tension, depression, neurasthenic symptoms or sleep disorders in neurosis. Cervical vertebral disease, low back pain and tension headache.
Drug Alert
Alert no data available
Before Consuming the Medicine
Avoid Drug Severe hepatic, renal, cardiac and cerebral organic disturbance, children, elderly patients, patients with weakness, driving, pregnancy, delivery or lactation, children.
Drug Special Care no data available
Drug Drug Interactions CNS depressants phenothiazines, barbiturates and alcohol; MAO inhibitors, Fluvoxamine maleate.
Drug Pregnancy Interaction Contraindicated
Drug Breast feeding Interaction Contraindicated
Drug Machinery Interaction Contraindicated
Drug More Information no data available
How to take the Medicine
Consumption Info no data available
Drug quanitty Anxiety : 0.51mg BID or TID, Panic disorders with agoraphobia : 0.5mg BID, Neurosis or depression : 1 mg TID, Psychosomatic disease, cervical vertebral disease, low back pain or Tension headache : 0.5mg TID, Sleep disorder : 13mg at bedtime. Maximum dose : Adults: 3 mg/day, Elderly 1.5mg/day. Treatment should be as short as possible; duratÏon of treatment should not exceed 8-12 weeks
Drug Dose no data available
Excess Drug Consumption Dail 1066. OR Contact doctor immediately
Forgot Drug Consumption Contact Your doctor
Stop Drug Consumption Do not stop the drug untill your doctor says you to do so.
Possible Side Effects
General Information no data available
Common Drug Side Effects Drowsiness, malaise, jaundice, thirst, nausea, retching, rash and weakness.
Rare Drug Side Effects no data available
Very Rare Drug Side Effects no data available
Drug Side Effects Symptoms no data available
How to Store the Medicine
How to Store the Medicine Store in a cool and dry place. Keep away from Children


Information for patients
Drug Information Escitalopram is used to treat depression. It belongs to a group of medicines called selective serotonin reuptake inhibitors (SSRIs). They are thought to work by their actions on brain chemicals called amines which are involved in controlling mood. Depression is longer lasting or more severe than the “low moods” everyone has from time to time due to the stress of everyday life. It is thought to be caused by a chemical imbalance in parts of the brain. This imbalance affects your whole body and can cause emotional and physical symptoms such as feeling low in spirit, loss of interest in activities, being unable to enjoy life, poor appetite or overeating, disturbed sleep, often waking up early, loss of sex drive, lack of energy and feeling guilty over nothing. Escitalopram corrects this chemical imbalance and may help relieve the symptoms of depression. Escitalopram may also be used to treat patients who may avoid and/or are fearful of social situations. Escitalopram may also be used to treat patients who have excessive anxiety and worry. Escitalopram may also be used to treat irrational fears or obsessional behaviour (obsessive- compulsive disorder). Obsessive-compulsive disorder involves having both obsessions and compulsions. Obsessions are unwanted thoughts that occur over and over again. Compulsions are the ongoing need to repeat certain actions as a result of these thoughts. Your doctor, however, may prescribe it for another purpose. Ask your doctor if you have any questions about why it has been prescribed for you. This medicine is only available with a doctor’s prescription. Escitalopram is not addictive.
Drug Alert
Before Consuming the Medicine
Avoid Drug Do not take Escitalopram if you are allergic to it, to any medicine containing citalopram, or any of the ingredients listed in the contents Symptoms of an allergic reaction may include shortness of breath, wheezing or difficulty breathing, swelling of the face, lips, tongue or other parts of the body, or rash, itching or hives on the skin. Do not take it after the expiry date printed on the pack. If you take it after the expiry date has passed, it may not work as well. The expiry date refers to the last day of the month. Do not take it if the packaging is torn or shows signs of tampering.
Drug Special Care Before you start to take it Tell your doctor if: 1. you have allergies to any other substances such as foods, preservatives or dyes. 2. you are pregnant or intend to become pregnant. 3. you are breast-feeding or planning to breast-feed. 4. you have, or have had, the following medical conditions: a tendency to bleed or bruise easily diabetes heart disease kidney disease liver disease bipolar disorder (manic depression) a history of seizures or fits restlessness and/or a need to move often. 5. you are receiving electroconvulsive therapy. Do not give Escitalopram to a child or adolescent. There is no experience with its use in children or adolescents under 18 years old. Escitalopram can be given to elderly patients over 65 years of age with a reduced dose. The effects of Escitalopram in elderly patients are similar to that in other patients. If you have not told your doctor about any of the above, tell them before you use Escitalopram. Things you must do If you are about to be started on any new medicine, remind your doctor and pharmacist that you are taking Escitalopram. Tell any other doctors, dentists and pharmacists who treat you that you are taking this medicine. Tell your doctor immediately if you have any suicidal thoughts or other mental or mood changes. All mentions of suicide or violence must be taken seriously. Occasionally, the symptoms of depression may include thoughts of suicide or self-harm. It is possible that these symptoms continue or get worse until the full antidepressant effect of the medicine becomes apparent. This is more likely to occur if you are a young adult, i.e. 18 to 24 years of age, and you have not used antidepressant medicines before. If you or someone you know demonstrates any of the following warning signs of suicide-related behaviour while taking Escitalopram, contact a health care provider immediately, or even go to the nearest hospital for treatment: thoughts or talk of death or suicide thoughts or talk of self-harm or harm to others any recent attempts of self-harm increase in aggressive behaviour, irritability or agitation. Do not stop taking this medicine or change the dose without consulting your doctor, even if you experience increased anxiety at the beginning of treatment. At the beginning of treatment, some patients may experience increased anxiety which will disappear during continued treatment. Tell your doctor immediately if you experience symptoms such as restlessness or difficulty in sitting or standing still. These symptoms can occur during the first weeks of treatment. Contact your doctor as soon as possible if you suddenly experience an episode of mania. Some patients with bipolar disorder (manic depression) may enter into a manic phase. This is characterised by profuse and rapidly changing ideas, exaggerated gaiety and excessive physical activity. Sometimes you may be unaware of the above-mentioned symptoms and therefore you may find it helpful to ask a friend or relative to help you to observe the possible signs of change in your behaviour. Things you must not do Do not give the tablets to anyone else, even if they have the same condition as you. Do not take Escitalopram to treat any other complaints unless your doctor tells you to. Do not stop taking Escitalopram, or lower the dosage, without checking with your doctor. Do not let yourself run out of medicine over the weekend or on holidays. Suddenly stopping Escitalopram may cause unwanted discontinuation symptoms such as dizziness, headache and nausea. Your doctor will tell you when and how Escitalopram should be discontinued. Your doctor will gradually reduce the amount you are using, usually over a period of one to two weeks, before stopping completely. Things to be careful of Avoid alcohol while you are taking this medicine. It is not advisable to drink alcohol while you are being treated for depression.
Drug Drug Interactions Do not take Escitalopram at the same time as the following other medicines: ? pimozide, a medicine used to treat mental disorders ? monoamine oxidase inhibitors (MAOIs), which are also used for the treatment of depression. Do not take Escitalopram when you are taking a MAOI or when you have been taking a MAOI within the last 14 days. Taking Escitalopram with MAOIs may cause a serious reaction with a sudden increase in body temperature, extremely high blood pressure and severe convulsions. Your doctor will know when it is safe to start Escitalopram after the MAOI has been stopped. Tell your doctor if you are taking any other medicines, including any that you buy without a prescription from your pharmacy, supermarket or health food shop. Some medicines and Escitalopram may interfere with each other. These include: ? bupropion, a medicine helping to treat nicotine dependence ? medicines used to treat reflux and ulcers, such as cimetidine, omeprazole, esomeprazole ? and lansoprazole ? medicines known to prolong bleeding, e.g. aspirin or other non-steroidal anti-inflammatory ? drugs (NSAIDs) ? ticlopidine and warfarin, medicines used to prevent blood clots ? mefloquine, an anti-malaria medicine ? sumatriptan, used to treat migraines ? tramadol, used to relieve pain ? medicines affecting the chemicals in the brain ? some heart medications, e.g. flecainide, propafenone, metoprolol ? tryptophan, an amino-acid ? lithium, used to treat mood swings and some types of depression ? antipsychotics, a class of medicines used to treat certain mental and emotional conditions, e.g. risperidone, thioridazine and haloperidol ? tricyclic antidepressants, e.g. imipramine, desipramine ? St John''s Wort (Hypericum perforatum), a herbal remedy ? any other medicines for depression, anxiety, obsessive-compulsive disorder or pre- menstrual dysphoric disorder. These medicines may be affected by Escitalopram, or may affect how well it works. You may need to use different amounts of your medicines, or take different medicines. Your doctor will advise you. Your doctor or pharmacist has more information on medicines to be careful with or avoid while taking Escitalopram.
Drug Pregnancy Interaction Do not take Escitalopram if you are pregnant unless you and your doctor have discussed the risks and benefits involved. If you take this medicine during the last three months of your pregnancy, the general condition of your newborn baby might be affected. Make sure your doctor and/or midwife know you are on Escitalopram. When taken during pregnancy, particularly in the last 3 months of pregnancy, medicines like Escitalopram may increase the risk of a serious condition in babies, called persistent pulmonary hypertension of the newborn (PPHN), making the baby breathe faster and appear bluish. These symptoms usually begin during the first 24 hours after the baby is born. If this happens to your baby you should contact your doctor and/or midwife immediately. If used during pregnancy Escitalopram should never be stopped abruptly. Ask your doctor or pharmacist for advice before taking any medicine.
Drug Breast feeding Interaction Do not take Escitalopram if you are breast-feeding unless you and your doctor have discussed the risks and benefits involved. It is not recommended that you breast-feed while taking Escitalopram as it is excreted in breast milk.
Drug Machinery Interaction Be careful driving or operating machinery until you know how Escitalopram affects you. It may cause nausea, fatigue and dizziness in some people, especially early in the treatment. If you have any of these symptoms, do not drive, operate machinery, or do anything else that could be dangerous.
Drug More Information
How to take the Medicine
Consumption Info
Drug quanitty Your doctor will decide what dose you will receive. Follow the instructions they give you. If you take the wrong dose, Escitalopram may not work as well and your condition may not improve. The standard dose for this medicine is 10 mg per day. This may be increased by your doctor to 20 mg per day. The recommended maximum dose in elderly patients is 10 mg per day. It is recommended that patients with liver disease receive an initial dose of 5 mg daily for the first two weeks. Your doctor may increase the dose to 10 mg daily. Your doctor may have prescribed a different dose. Ask your doctor or pharmacist if you are unsure of the correct dose for you. They will tell you exactly how much to take.
Drug Dose How to take it To remove tablet: - It is not recommended that you push the tablet through both layers of paper and foil. Peeling back the top layer of paper first, (as shown by an arrow on the corner of the blister), will expose the foil which when broken, will allow you to release the tablet from the blister bubble. Swallow the tablets whole with a full glass of water. Do not chew them. When to take it Take Escitalopram as a single dose either in the morning or in the evening. Take Escitalopram with or without food. How long to take it Continue to take Escitalopram even if it takes some time before you feel any improvement in your condition. As with other medicines for the treatment of these conditions it may take a few weeks before you feel any improvement. Individuals will vary greatly in their response to Escitalopram. Your doctor will check your progress at regular intervals. The duration of treatment may vary for each individual, but is usually at least 6 months. In some cases the doctor may decide that longer treatment is necessary. Continue taking your medicine for as long as your doctor tells you, even if you begin to feel better. The underlying illness may persist for a long time and if you stop your treatment too soon, your symptoms may return.
Excess Drug Consumption Immediately telephone your doctor, or the Poisons Information Centre or go to Accident and Emergency at your nearest hospital, if you think you or anyone else may have taken too much Escitalopram. Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention.Symptoms of an overdose may include dizziness, low blood pressure, nausea (feeling sick), vomiting, agitation, tremor (shaking) and rarely convulsions and coma.
Forgot Drug Consumption If you miss a dose and remember in less than 12 hours, take it straight away, and then go back to taking it as you would normally. Otherwise, if it is almost time for your next dose, skip the dose you missed and take the next dose when you are meant to. Do not take a double dose to make up for the dose you have missed. If you are not sure what to do, ask your doctor or pharmacist. If you have trouble remembering when to take your medicine, ask your pharmacist for hints.
Stop Drug Consumption Do not stop taking this medicine suddenly. If Escitalopram is stopped suddenly you may experience mild, but usually temporary, symptoms such as dizziness, pins and needles, electric shock sensations, sleep disturbances (vivid dreams, inability to sleep), feeling anxious or agitated, headaches, feeling sick (nausea), vomiting, sweating, tremor (shaking), feeling confused, feeling emotional or irritable, diarrhoea, visual disturbances, or fast or irregular heart beats. When you have completed your course of treatment, the dose of Escitalopram is gradually reduced over a couple of weeks rather than stopped abruptly. Your doctor will tell you how to reduce the dosage so that you do not get these unwanted effects.
Possible Side Effects
General Information All medicines may have some unwanted side effects. Sometimes they are serious, but most of the time they are not. Your doctor has weighed the risks of using this medicine against the benefits he/she expects it will have for you. Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking Escitalopram. It helps most people with depression, social anxiety disorder (social phobia), generalised anxiety disorder and obsessive-compulsive disorder, but it may have unwanted side effects in a few people. The side effects of Escitalopram are, in general, mild and disappear after a short period of time. Tell your doctor if you notice anything else that is making you feel unwell. Other side effects not listed above may occur in some people. Do not be alarmed by this list of possible side effects. You may not experience any of them.
Common Drug Side Effects Tell your doctor if you notice any of the following and they worry you: ? decreased appetite or loss of appetite ? dry mouth ? diarrhoea ? nausea (feeling sick) ? sleeplessness ? fatigue, sleepiness or drowsiness, yawning ? increased sweating ? sexual disturbances (decreased sexual drive; problems with ejaculation or erection; women may experience difficulties achieving orgasm).
Rare Drug Side Effects Tell your doctor as soon as possible if you notice any of the following: ? agitation, confusion, panic attacks, anxiety, restlessness ? dizziness ? dizziness when you stand up due to low blood pressure ? low sodium levels in the blood (the symptoms are feeling sick and unwell with weak muscles or feeling confused) ? abnormal liver function tests (increased amounts of liver enzymes in the blood) ? difficulties urinating ? unusual secretion of breast milk ? increased tendency to develop bruises ? rash, itching, patches of circumscribed swellings. These may be serious side effects of Escitalopram. You may need urgent medical attention.
Very Rare Drug Side Effects Tell your doctor immediately, or go to Accident and Emergency at your nearest hospital, if you notice any of the following: ? serious allergic reaction ? (symptoms of an allergic reaction may include swelling of the face, lips, mouth or throat ? which may cause difficulty in swallowing or breathing, or hives) ? high fever, agitation, confusion, trembling and abrupt contractions of muscles ? (these symptoms may be signs of a rare condition called serotonin syndrome)* ? mania*, hallucinations ? seizures, tremors, movement disorders (involuntary movements of the muscles)*. These are very serious side effects. You may need urgent medical attention or hospitalisation. *The side effects marked with an asterisk (*) are a number of rare side effects that are known to occur with medicines that work in a similar way to Escitalopram.
Drug Side Effects Symptoms
How to Store the Medicine
How to Store the Medicine Storage Keep Escitalopram tablets in the blister pack until it is time to take them. If you take the tablets out of the box or the blister pack they may not keep well. Keep Escitalopram tablets in a cool dry place where the temperature stays below 30°C. Keep Escitalopram oral solution in a cool dry place where the temperature stays below 25°C. Discard Escitalopram oral solution 3 months after first opening. Do not store it or any other medicine in the bathroom, near a sink, or on a window-sill. Do not leave it in the car. Heat and damp can destroy some medicines. Keep it where children cannot reach it. A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines. Disposal If your doctor tells you to stop taking Escitalopram, or the medicine has passed its expiry date, ask your pharmacist what to do with any that is left over. Return any unused medicine to your pharmacist.

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