PLANEP 50MG TABLET

Manufacturer : LUP-LUPIN LABORATORIES
Composition : EPLERENONE-50MG
Dose Form : TABLET
Description : PLANEP 50MG TAB
Route Of Administration : ORAL
Pack : 10
In stock
SKU
PLA0190
₹324.35
Manufacturer : LUP-LUPIN LABORATORIES
Composition : EPLERENONE-50MG
Dose Form : TABLET
Description : PLANEP 50MG TAB
Route Of Administration : ORAL
Pack : 10

Drug Ingredient Information

EPLERENONE-50MG

EPLERENONE

Information for patients
Drug Information Eplerenone belongs to a group of medicines known as selective aldosterone blocking agents. These blocking agents inhibit the action of aldosterone, a substance produced within the body, which controls your blood pressure and heart function. High levels of aldosterone can cause changes in your body that lead to heart failure.Eplerenone can help prevent worsening heart failure after a heart attack, in combination with other drugs that are used to treat your heart failure.
Drug Alert
Alert if you are hypersensitive (allergic) to eplerenone or to any other ingredients of Eplerenone if you have high levels of potassium in your blood (hyperkalemia) if you are taking groups of drugs which help you to excrete excessive body fluid, (potassium sparing diuretics) or “salt tablets” (potassium supplements) if you have moderate to severe kidney disease if you have severe liver disease if you are taking medicines that are used to treat fungal infection (ketoconazole or itraconazole) if you are taking antiviral medication for treating HIV (nelfinavir or ritonavir) if you are taking antibiotics used to treat bacterial infections (clarithromycin or telithromycin) if you are taking nefazodone used to treat depression.
Before Consuming the Medicine
Avoid Drug if you are hypersensitive (allergic) to eplerenone or to any other ingredients of Eplerenone if you have high levels of potassium in your blood (hyperkalemia) if you are taking groups of drugs which help you to excrete excessive body fluid, (potassium sparing diuretics) or “salt tablets” (potassium supplements) if you have moderate to severe kidney disease if you have severe liver disease if you are taking medicines that are used to treat fungal infection (ketoconazole or itraconazole) if you are taking antiviral medication for treating HIV (nelfinavir or ritonavir) if you are taking antibiotics used to treat bacterial infections (clarithromycin or telithromycin) if you are taking nefazodone used to treat depression.
Drug Special Care if you have kidney or liver disease (see also “Do not take Eplerenone”) if you are taking lithium (usually given for manic depressive disorder, also called bipolar disorder) if you are taking tacrolimus or cyclosporin (used to treat skin conditions such as psoriasis or eczema, and to prevent rejection after organ transplantation)
Drug Drug Interactions Itraconazole or ketoconazole (used to treat fungal infections), ritonavir, nelfinavir (antiviral medication for treating HIV), clarithromycin, telithromycin (used to treat bacterial infections) or nefazodone (used to treat depression) as these drugs reduce the break-down of Eplerenone, thereby prolonging its effect on the body. Potassium sparing diuretics (drugs which help you to excrete excess body fluid) and potassium supplements (salt tablets) as these drugs increase the risk of high potassium levels in your blood. Please inform your doctor if you are taking any of the following medicines: Lithium (usually given for manic depressive disorder, also called bipolar disorder). Use of lithium together with diuretics and ACE inhibitors (used to treat high blood pressure and heart disease) has been shown to cause levels of lithium in the blood to become too high, which may cause side effects of: loss of appetite; visual impairment; tiredness; muscle weakness; muscle twitches. Cyclosporin or tacrolimus (used to treat skin conditions such as psoriasis or eczema, and to prevent rejection after organ transplantation). These drugs can cause kidney problems and therefore increase the risk of high potassium levels in your blood. Non-steroidal anti-inflammatory drugs (NSAIDs - certain pain killers such as ibuprofen, used to relieve pain, stiffness and inflammation). These drugs may lead to kidney problems and therefore increase the risk of high potassium levels in your blood. Trimethoprim (used to treat bacterial infections) may increase the risk of high potassium levels in your blood. ACE inhibitors (such as enalapril) and angiotensin II receptor antagonists (such as candesartan) (which are used to treat high blood pressure, heart disease or particular kidney conditions) may increase the risk of high potassium levels in your blood. -Alpha I blockers, such as prazosin or alfuzosin (used to treat high blood pressure and particular prostate conditions) may lead to a fall in blood pressure and dizziness upon standing. -Tricyclic antidepressants such as amitryptyline or amoxapine (for treatment of depressions), antipsychotics (also known as neuroleptics) such as chlorpromazine or haloperidol (for the treatment of psychiatric disorders), amifostine (used during cancer chemotherapy) and baclofen (used to treat muscle spasm). These drugs may lead to a fall in blood pressure and dizziness upon standing. -Glucocorticoids, such as hydrocortisone or prednisone (used to treat inflammation and certain skin conditions) and tetracosactide (mainly used for diagnosing and treating disorders of the adrenal cortex) may reduce the blood-pressure lowering effect of Eplerenone. -Digoxin (used in the treatment of heart conditions). Digoxin blood levels may be increased when taken together with Eplerenone. -Warfarin (an anti-clotting drug): Caution is warranted when taking warfarin because high levels of warfarin in the blood may cause changes in the effect of Eplerenone on the body. -Erythromycin (used to treat bacterial infections), saquinavir (antiviral medication for treating HIV), fluconazole (used to treat fungal infections), amiodarone, diltiazem and verapamil (for the treatment of heart problems and high blood pressure) reduce the break-down of Eplerenone thereby prolonging the effect of Eplerenone on the body. -St John's Wort (herbal medicinal product), rifampicin (used to treat bacterial infections), carbamazepine, phenytoin, and phenobarbital (used, among others, to treat epilepsy) may increase the break-down of Eplerenone and thus decrease its effect.
Drug Pregnancy Interaction Ask your doctor or pharmacist for advice before taking any medicine. The effect of Eplerenone has not been evaluated during pregnancy in humans.
Drug Breast feeding Interaction It is not known if eplerenone is excreted in human breast milk. A decision should be made with your doctor, whether to discontinue breast-feeding or to discontinue the drug.
Drug Machinery Interaction You may feel dizzy after taking Eplerenone. If this should happen, do not drive or operate machinery.
Drug More Information Eplerenone may be taken with or without food.
How to take the Medicine
Consumption Info no data available
Drug quanitty Eplerenone is usually administered together with other medication for heart failure eg beta blockers. The usual starting dose is one 25 mg tablet once daily, increasing after about 4 weeks to 50 mg once daily (either as one 50 mg tablet or two 25 mg tablets). Blood potassium levels should be measured before starting Eplerenone therapy, within the first week and at one month after the start of treatment or after a change in dose. The dose may be adjusted by your doctor, depending on the potassium levels in your blood. In patients with mild kidney disease and patients with mild-to-moderate liver disease no adjustment of the starting dose is required. If you have liver or kidney problems, you may need more frequent testing of your blood potassium levels.
Drug Dose Always take Eplerenone exactly as your doctor has told you. You should check with your doctor or pharmacist if you are not sure. Eplerenone tablets may be taken together with food or on an empty stomach. Swallow the tablets whole with plenty of water.
Excess Drug Consumption If you take more Eplerenone than you should, tell your doctor or pharmacist immediately. If you have taken too much of your medicine, the most likely symptoms will be low blood pressure (expressed as a light feeling in your head, dizziness, blurred vision, weakness, acute loss of consciousness) or hyperkalemia, high levels of potassium in the blood (expressed by muscle cramps, diarrhoea, nausea, dizziness or headache).
Forgot Drug Consumption If it is almost time for your next tablet, skip the tablet you missed and take your next tablet when it is due. Otherwise take the tablet as soon as you remember, providing there is more than 12 hours to when you are due to take your next tablet. Then go back to taking your medicine as you would normally.Do not take a double dose to make up for the forgotten tablet.
Stop Drug Consumption It is important to keep taking Eplerenone as prescribed unless your doctor tells you to stop your treatment.
Possible Side Effects
General Information swollen face, tongue or throat difficulty swallowing hives and difficulties breathing These are the symptoms of angioneurotic oedema.
Common Drug Side Effects elevated potassium level in your blood (symptoms include muscle cramps, diarrhoea, nausea, dizziness or headache) dizziness low blood pressure diarrhoea nausea abnormal functioning of your kidney rash
Rare Drug Side Effects eosinophilia (increase in certain white blood cells) dehydration elevated quantity of cholesterol or triglycerides (fats) in your blood low sodium blood levels insomnia (difficulty sleeping) headache heart complaints eg irregular heart beat, heart attack and heart failure decreased blood pressure that can cause dizziness upon standing thrombosis (blood clot) in the leg sore throat flatulence vomiting itching increased sweating back pain leg cramps feeling weak and generally unwell increased urea and creatinine blood levels which may indicate kidney problems kidney inflammation enlargement of breasts in men
Very Rare Drug Side Effects no data available
Drug Side Effects Symptoms no data available
How to Store the Medicine
How to Store the Medicine Keep out of the reach and sight of children.This medicinal product does not require any special storage conditions. Do not use Eplerenone film-coated tablets after the expiry date {EXP} stated on the pack and blister. The expiry date refers to the last day of that month. Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.

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