| Information for
patients
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| Drug Information |
Ceftriaxone contains a medicine called ceftriaxone. This belongs to a group of medicines called antibiotics.
•Ceftriaxone is used to treat infections caused by bacteria.
•It can be used to treat infections in different parts of the body including the lungs (pneumonia), blood (septicaemia), skin, other soft body parts (tissues), bone, and for infections such as meningitis and gonorrhoea (a sexually transmitted infection).
•It can be used to treat infections in people with low numbers of white blood cells (neutropenia).
•It can also be given before and after operations to stop infections from happening.
It works by stopping the bacteria from growing properly. This causes the bacteria to die. |
| Drug Alert |
| Alert |
•You are allergic (hypersensitive) to ceftriaxone (the only ingredient in Ceftriaxone ).
•You are allergic to antibiotics called ‘cephalosporins’. These include cefalexin, cefaclor and cefuroxime.
•You have had a sudden or severe allergic reaction to penicillin or similar antibiotics (such as amoxicillin or flucloxacillin). The signs include sudden swelling of the throat or face which might make it difficult to breathe or swallow, sudden swelling of the hands, feet and ankles, and a severe rash that develops quickly.
•You are allergic to lidocaine and you are to be given Ceftriaxone as an injection into a muscle
You must not be given Ceftriaxone if any of the above apply to you. If you are not sure, talk to your doctor or nurse before having Ceftriaxone .
Ceftriaxone must not be given to babies if:
•The baby is premature.
•The baby is newborn (up to 28 days) and has certain blood problems or jaundice (yellowing of the skin or the whites of the eyes) or is about to be given another injection that contains calcium.. |
| Before Consuming
the Medicine
|
| Avoid Drug |
•You are allergic (hypersensitive) to ceftriaxone (the only ingredient in Ceftriaxone ).
•You are allergic to antibiotics called ‘cephalosporins’. These include cefalexin, cefaclor and cefuroxime.
•You have had a sudden or severe allergic reaction to penicillin or similar antibiotics (such as amoxicillin or flucloxacillin). The signs include sudden swelling of the throat or face which might make it difficult to breathe or swallow, sudden swelling of the hands, feet and ankles, and a severe rash that develops quickly.
•You are allergic to lidocaine and you are to be given Ceftriaxone as an injection into a muscle
You must not be given Ceftriaxone if any of the above apply to you. If you are not sure, talk to your doctor or nurse before having Ceftriaxone .
Ceftriaxone must not be given to babies if:
•The baby is premature.
•The baby is newborn (up to 28 days) and has certain blood problems or jaundice (yellowing of the skin or the whites of the eyes) or is about to be given another injection that contains calcium.. |
| Drug Special Care |
Check with your doctor or nurse before having Ceftriaxone if:
•You have had a mild allergic reaction to penicillin or similar antibiotics (such as a skin rash which may have been itchy).
•You are allergic to anything not already mentioned in this leaflet.
•You have asthma.
•You have recently received or are about to receive calcium.
•You have ever had problems with your gut, in particular colitis (inflammation of the bowel).
•You have liver or kidney problems.
•You have other illnesses, such as blood problems.
•You are on a low sodium diet.
If any of the above apply to you, or if you are not sure, talk to your doctor or nurse before you have Ceftriaxone . |
| Drug Drug Interactions |
Please tell your doctor or nurse if you are taking or have recently taken any other medicines. This includes medicines that you buy without a prescription and herbal medicines. This is because Ceftriaxone can affect the way some medicines work. Also some medicines can affect the way Ceftriaxone works.
In particular, tell your doctor or nurse if you are taking any of the following medicines:
•Oral contraceptives (the pill). Ceftriaxone can stop the pill from working, so you should use extra barrier contraception methods (such as condoms) while you are taking Ceftriaxone and for one month afterwards.
•Chloramphenicol (used to treat infections, particularly of the eyes).
•Anticoagulants (medicines used to thin the blood).
•Probenecid (used to treat gout).
•Amsacrine (an anti-cancer medicine).
•Fluconazole (an anti-fungal medicine).
•Vancomycin or other antibiotics (used to treat infections). |
| Drug Pregnancy Interaction |
Talk to your doctor before taking this medicine if you are pregnant, might become pregnant, or are breast-feeding. |
| Drug Breast feeding Interaction |
Talk to your doctor before taking this medicine if you are pregnant, might become pregnant, or are breast-feeding. |
| Drug Machinery Interaction |
Ceftriaxone can cause dizziness. Talk to your doctor if any of these happen to you and do not drive or use any tools or machines |
| Drug More Information |
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| How to take the
Medicine
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| Consumption Info |
|
| Drug quanitty |
Adults, the elderly and children aged 12 years and over
•The usual dose is 1 g (gram) once a day. If you have a severe infection, your doctor may give you a higher dose (between 2 g and 4 g once a day).
•If you are going to have an operation you may be given between 1 g and 2 g in one or two injections.
•The usual treatment for an infection called ‘gonorrhoea’ is one dose of 250 mg (milligrams), given as an injection into a muscle.
Children up to 12 years
•The dose is worked out by the doctor based on the child’s weight. The medicine is usually given to the child once a day through a small tube into a vein (intravenous infusion). This usually takes at least 30 minutes.
Newborn babies
•The dose is worked out by the doctor based on the baby’s weight. The medicine is usually given to the baby once a day through a small tube into a vein (intravenous infusion). This usually takes 1 hour.
People with liver and kidney problems
•If you have problems with your liver and kidneys, you may be given a lower dose. You may need to have blood tests to check that you are getting the dose you need. |
| Drug Dose |
Ceftriaxone will be given to you by a doctor or nurse. It will be given to you in one of the following ways:
•As an injection into a muscle (such as the muscle in your arm).
•By slow injection into one of your veins. This may take between 2 and 4 minutes.
•Through a small tube into one of your veins. This is called an ‘intravenous infusion’. It may take at least 30 minutes. The number of days or weeks that you are given Ceftriaxone for depends on what sort of infection you have.
You will usually continue to be given Ceftriaxone for 2 to 3 days after you have started to recover from your illness |
| Excess Drug Consumption |
•If you think you have been given too much Ceftriaxone , tell your doctor or nurse.
If you have any further questions on the use of this medicine, ask your doctor or nurse |
| Forgot Drug Consumption |
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| Stop Drug Consumption |
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| Possible Side
Effects
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| General Information |
Severe allergic reactions (uncommon, affect less than 1 in 100 people)
If you have a severe allergic reaction, tell a doctor straight away. The signs may include:
•Sudden swelling of the face, throat, lips or mouth. This can make it difficult to breathe or swallow.
•Sudden swelling of the hands, feet and ankles.
Severe skin rashes (very rare, affect less than 1 in 10,000 people)
If you get a severe skin rash, tell a doctor straight away.
•The signs may include a severe rash that develops quickly, with blisters or peeling of the skin and possibly blisters in the mouth. |
| Common Drug Side Effects |
•Loose stools or diarrhoea.
•Feeling sick or being sick. |
| Rare Drug Side Effects |
•Other types of infection, such as those caused by fungi and yeasts (for example, thrush).
•Blood problems. The signs include feeling tired, bruising easily, being short of breath and nosebleeds.
•Headache
•Feeling dizzy.
•A sore mouth.
•Inflammation of the tongue (glossitis). The signs include swelling, redness and soreness of the tongue.
•Liver problems (shown in a blood test).
•Problems with your gallbladder which may cause pain, feeling sick and being sick.
•Kidney problems. These may affect the amount of water (urine) that you pass. Some people pass less water than usual. Very rarely, people stop passing water altogether.
•Blood or sugar in your urine.
•Pain or a burning feeling along the vein where Ceftriaxone has been given.
•Pain where the injection was given.
•A high temperature (fever) or shivering. |
| Very Rare Drug Side Effects |
•Positive results in a Coombs’ test (a test for some blood problems).
•Problems with the way your blood clots. The signs include bruising easily and pain and swelling of your joints.
•Changes in the numbers of white cells in your blood. The signs include a sudden high temperature (fever), shivering and a sore throat.
•Inflammation of the pancreas (pancreatitis). The signs include severe pain in the stomach which spreads to your back.
•Inflammation of the large bowel (colon). The signs include diarrhoea, usually with blood and mucus, stomach pain and fever. |
| Drug Side Effects Symptoms |
•Other skin reactions. These include a rash which may cover a lot of your body, a lumpy rash (hives), feeling itchy and swelling |
| How to Store the
Medicine
|
| How to Store the Medicine |
•Your doctor or pharmacist is responsible for storing Ceftriaxone . They are also responsible for disposing of any unused Ceftriaxone correctly.
•Keep out of the reach and sight of children.
•Do not store Ceftriaxone above 25°C.
•Do not use Ceftriaxone after the expiry date printed on the pack. |
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