PREZAR H TABLET

Manufacturer : MEE-MEDI CHEM PHARMA
Composition : LOSARTAN-50MG+HYDROCHLOROTHIAZIDE-12.5MG
Dose Form : TABLET
Description : PREZAR - H TAB
Route Of Administration : ORAL
Pack : 10
In stock
SKU
PRE0123
₹76.00
Manufacturer : MEE-MEDI CHEM PHARMA
Composition : LOSARTAN-50MG+HYDROCHLOROTHIAZIDE-12.5MG
Dose Form : TABLET
Description : PREZAR - H TAB
Route Of Administration : ORAL
Pack : 10

Drug Ingredient Information

LOSARTAN-50MG+HYDROCHLOROTHIAZIDE-12.5MG

LOSARTAN

Information for patients
Drug Information Losartan belongs to a group of medicines known as angiotensin-II receptor antagonists. Angiotensin-II is a substance produced in the body which binds to receptors in blood vessels, causing them to tighten. This results in an increase in blood pressure. Losartan prevents the binding of angiotensin-II to these receptors, causing the blood vessels to relax which in turn lowers the blood pressure. Losartan slows the decrease of kidney function in patients with high blood pressure and type 2 diabetes. Losartan potassium is used to treat patients with high blood pressure (hypertension) in adults and in children and adolescents 6-18 years of age. to protect the kidney in hypertensive type 2 diabetic patients with laboratory evidence of impaired renal function and proteinuria = 0.5 g per day (a condition in which urine contains an abnormal amount of protein). to treat patients with chronic heart failure when therapy with specific medicines called angiotensin-converting-enzyme inhibitors (ACE inhibitors, medicine used to lower high blood pressure) is not considered suitable by your doctor. If your heart failure has been stabilised with an ACE inhibitor you should not be switched to losartan. in patients with high blood pressure and a thickening of the left ventricle, LOSARTAN POTASSIUM has been shown to decrease the risk of stroke (“LIFE indication”).
Drug Alert
Alert if you are allergic (hypersensitive) to losartan or to any of its other ingredients, if your liver function is severely impaired, if you are more than 3 months pregnant.
Before Consuming the Medicine
Avoid Drug if you are allergic (hypersensitive) to losartan or to any of its other ingredients, if your liver function is severely impaired, if you are more than 3 months pregnant.
Drug Special Care if you have had a history of angiooedema (swelling of the face, lips, throat, and/or tongue). if you suffer from excessive vomiting or diarrhoea leading to an extreme loss of fluid and/or salt in your body, if you receive diuretics (medicines that increase the amount of water that you pass out through your kidneys) or are under dietary salt restriction leading to an extreme loss of fluid and salt in your body. if you are known to have narrowing or blockage of the blood vessels leading to your kidneys or if you have received a kidney transplant recently, if your liver function is impaired. if you suffer from heart failure with or without renal impairment or concomitant severe life threatening cardiac arrhythmias. Special caution is necessary when you are treated with a ß-blocker concomitantly, if you have problems with your heart valves or heart muscle, if you suffer from coronary heart disease (caused by a reduced blood flow in the blood vessels of the heart) or from cerebrovascular disease (caused by a reduced blood circulation in the brain), if you suffer from primary hyperaldosteronism (a syndrome associated with increased secretion of the hormone aldosterone by the adrenal gland, caused by an abnormality within the gland).
Drug Drug Interactions Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines,including medicines obtained without a prescription or herbal medicines and natural products.Take particular care if you are taking the following medicines while under treatment with Losartan potassium other blood pressure lowering medicines as they may additionally reduce your blood pressure.?Blood pressure may also be lowered by one of the following drugs/ class of drugs: tricyclic?antidepressants, antipsychotics, baclofen, amifostine, medicines which retain potassium or may increase potassium levels (e.g. potassium supplements, potassium-containing salt substitutes or potassium-sparing medicines such as certain diuretics [amiloride, triamterene, spironolactone] or heparin), non-steroidal anti-inflammatory drugs such as indometacin, including COX-2-inhibitors (medicines that reduce inflammation, and can be used to help relieve pain) as they may reduce the blood pressure lowering effect of losartan. If your kidney function is impaired, the concomitant use of these medicines may lead to a worsening of the kidney function. Lithium containing medicines should not be taken in combination with losartan without close supervision by your doctor. Special precautionary measures (e.g. blood tests) may be appropriate.
Drug Pregnancy Interaction You must tell your doctor if you think you are (or might become) pregnant. Your doctor will normally advise you to stop taking Losartan potassium before you become pregnant or as soon as you know you are pregnantand will advise you to take another medicine instead of Losartan potassium. Losartan potassium is not recommended in early pregnancy, and must not be taken when more than 3 months pregnant, as it may cause serious harm to your baby if used after the third month of pregnancy.
Drug Breast feeding Interaction Tell your doctor if you are breast feeding or about to start breast feeding. Losartan potassium is not recommended for mothers who are breast feeding, and your doctor may choose another treatment for you if you wish to breast feed. Especially if your baby is a newborn, or born prematurely. Ask your doctor or pharmacist for advice before taking any medicine.
Drug Machinery Interaction No studies on the effects on the ability to drive and use machines have been performed.Losartan potassium is unlikely to affect your ability to drive or use machines. However, as with many other medicines used to treat high blood pressure, losartan may cause dizziness or drowsiness in some people. If you experience dizziness or drowsiness, you should consult your doctor before attempting such activities.
Drug More Information Losartan potassium has been studied in children. For more information,, talk to your doctor.
How to take the Medicine
Consumption Info Losartan potassium may be taken with or without food.
Drug quanitty The doctor may advise a lower dose, especially when starting treatment in certain patients such as those treated with diuretics in high doses, in patients with liver impairment, or in patients over the age of 75 years. The use of losartan is not recommended in patients with severe hepatic impairment. Adult patients with high blood pressure Treatment usually starts with 50 mg losartan (one tablet Losartan potassium 50 mg) once a day. The maximal blood pressure lowering effect should be reached 3-6 weeks after beginning treatment. In some patients the dose may later be increased to losartan (two Losartan potassium 50 mg) once daily. If you have the impression that the effect of losartan is too strong or too weak, please talk to your doctor or pharmacist. Use in children and adolescents (6 to 18 years old) The recommended starting dose in patients who weigh between 20 and 50 kg is 0.7 mg of losartan per kg of body weight administered once a day (up to 25 mg of Losartan potassium). The doctor may increase the dose if blood pressure is not controlled. Adult patients with high blood pressure and type 2 diabetes Treatment usually starts with 50 mg losartan (one tablet Losartan potassium 50 mg) once a day. The dose may later be increased to losartan (two Losartan potassium 50 mg) once daily depending on your blood pressure response. Losartan may be administered with other blood pressure lowering medicines (e.g. diuretics, calcium channel blockers, alpha- or beta-blockers, and centrally acting agents) as well as with insulin and other commonly used medicines that decrease the level of glucose in the blood (e.g. sulfonylureas, glitazones and glucosidase inhibitors). Adult Patients with heart failure Treatment usually starts with 12.5 mg losartan (one tablet Losartan potassium 12.5 mg) once a day. Generally, the dose should be increased weekly step-by-step (i.e., 12.5 mg daily during the first week, 25 mg daily during the second week, 50 mg daily during the third week, daily during the fourth week, 150 mg daily during the fifth week) up to the maintenance dose as determined by your physician. A maximum dose of 150 mg losartan (for example, three of Losartan potassium 50 mg or one tablet each of Losartan potassium and Losartan potassium 50 mg) once daily may be used. In the treatment of heart failure, losartan is usually combined with a diuretic (medicine that increases the amount of water that you pass out through your kidneys) and/or digitalis (medicine that helps to make the heart stronger and more efficient) and/or a beta-blocker.
Drug Dose The should be swallowed with a glass of water. You should try to take your daily dose at about the same time each day. It is important that you continue to take Losartan potassium until your doctor tells you otherwise.
Excess Drug Consumption If you accidentally take too many, contact your doctor immediately. Symptoms of overdose are low blood pressure, increased heartbeat, possibly decreased heartbeat.
Forgot Drug Consumption If you accidentally miss a daily dose, just take the next dose as normal. Do not take a double dose to make up for a forgotten tablet. If you have any further questions on the use of this product, ask your doctor or pharmacist.
Stop Drug Consumption Do not stop the drug untill your doctor says you to do so.
Possible Side Effects
General Information dizziness, low blood pressure, debility, fatigue, too little sugar in the blood (hypoglycaemia), too much potassium in the blood (hyperkalaemia), changes in kidney function including kidney failure, reduced number of red blood cells (anaemia), increase in blood urea, serum creatinine and serum potassium in patients with heart failure
Common Drug Side Effects somnolence, headache, sleep disorders, feeling of increased heart rate (palpitations), severe chest pain (angina pectoris), low blood pressure (especially after excessive loss of water from the body within blood vessels e.g. in patients with severe heart failure or under treatment with high dose diuretics), dose-related orthostatic effects such as lowering of blood pressure appearing when rising from a lying or sitting position, shortness of breath (dyspnoea), abdominal pain, obstipation, diarrhoea, nausea, vomiting, hives (urticaria), itching (pruritus), rash, localised swelling (oedema), cough. hypersensitivity, angiooedema, inflammation of blood vessels (vasculitis including Henoch-Schonlein purpura), numbness or tingling sensation (paraesthesia), fainting (syncope), very rapid and irregular heartbeat (atrial fibrillation) brain attack (stroke), inflammation of the liver (hepatitis), elevated blood alanine aminotransferase (ALT) levels, usually resolved upon discontinuation of treatment.
Rare Drug Side Effects reduced number of thrombocytes, migraine, liver function abnormalities, muscle and joint pain, flu-like symptoms, back pain and urinary tract infection, increased sensitivity to the sun (photosensitivity), unexplained muscle pain with dark (tea-coloured) urine (rhabdomyolysis), impotence, inflammation of the pancreas (pancreatitis), low levels of sodium in the blood (hyponatraemia), depression, generally feeling unwell (malaise), ringing, buzzing, roaring, or clicking in the ears (tinnitus).
Very Rare Drug Side Effects no data available
Drug Side Effects Symptoms no data available
How to Store the Medicine
How to Store the Medicine Keep out of the reach and sight of children.Do not use Losartan potassium after the expiry date which is stated on the carton or the bottle label. The expiry date refers to the last day of that month. Blisters Store Losartan potassium in the original package in order to protect from light and moisture. Do not open the blister pack until you are ready to take the medicine. Bottles Store Losartan potassium in the original container in order to protect from light. Do not store above 25OC.Keep the bottle tightly closed in order to protect from moisture.Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment

HYDROCHLOROTHIAZIDE

Information for patients
Drug Information Hydrochlorothiazide, a 'water pill,' is used to treat high blood pressure and fluid retention caused by various conditions, including heart disease. It causes the kidneys to get rid of unneeded water and salt from the body into the urine. This medicine is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.Hydrochlorothiazide may also be used to treat patients with diabetes insipidus and certain electrolyte disturbances and to prevent kidney stones in patients with high levels of calcium in their blood. Talk to your doctor about the possible risks of using this medicine for your condition.
Drug Alert
Alert You should not use this medication if you are allergic to hydrochlorothiazide or if you are unable to urinate. Before using hydrochlorothiazide, tell your doctor if you have liver disease, kidney disease, glaucoma, asthma or allergies, gout, diabetes, or if you are allergic to sulfa drugs or penicillin. Avoid drinking alcohol, which can increase some of the side effects of hydrochlorothiazide. Avoid becoming overheated or dehydrated during exercise and in hot weather. Follow your doctor's instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough. There are many other drugs that can interact with hydrochlorothiazide. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you. If you are being treated for high blood pressure, keep using hydrochlorothiazide even if you feel fine. High blood pressure often has no symptoms.
Before Consuming the Medicine
Avoid Drug You should not use this medication if you are allergic to hydrochlorothiazide, or if you are unable to urinate. To make sure you can safely take hydrochlorothiazide, tell your doctor if you have any of these other conditions: kidney disease; liver disease; glaucoma; asthma or allergies; gout; diabetes; or an allergy to sulfa drugs. FDA pregnancy category B. Hydrochlorothiazide is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Hydrochlorothiazide can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
Drug Special Care tell your doctor and pharmacist if you are allergic to hydrochlorothiazide, sulfa drugs, or any other drugs. tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially other medicines for high blood pressure, anti-inflammatory medications such as ibuprofen (Motrin, Nuprin) or naproxen (Aleve), corticosteroids (e.g., prednisone), lithium (Eskalith, Lithobid), medications for diabetes, probenecid (Benemid), and vitamins. If you also are taking cholestyramine or colestipol, take it at least 1 hour after hydrochlorothiazide. tell your doctor if you have or have ever had diabetes, gout, or kidney, liver, thyroid, or parathyroid disease. tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking hydrochlorothiazide, call your doctor immediately. if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking hydrochlorothiazide. you should know that this drug may make you drowsy. Do not drive a car or operate machinery until you know how this drug affects you. remember that alcohol can add to the drowsiness caused by this drug. plan to avoid unnecessary or prolonged exposure to sunlight and to wear protective clothing, sunglasses, and sunscreen. Hydrochlorothiazide may make your skin sensitive to sunlight.
Drug Drug Interactions lithium (Eskalith, Lithobid); digoxin (Lanoxin); cholestyramine (Prevalite, Questran) or colestipol (Colestid); steroids (prednisone and others); other blood pressure medications; NSAIDs (non-steroidal anti-inflammatory drugs) such as aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn, Naprelan, Treximet), celecoxib (Celebrex), diclofenac (Arthrotec, Cambia, Cataflam, Voltaren, Flector Patch, Pennsaid, Solareze), indomethacin (Indocin), meloxicam (Mobic), and others; or insulin or oral diabetes medication.
Drug Pregnancy Interaction
Drug Breast feeding Interaction
Drug Machinery Interaction
Drug More Information Follow your doctor's directions. They may include following a daily exercise program or a low-salt or low-sodium diet, potassium supplements, and increased amounts of potassium-rich foods (e.g., bananas, prunes, raisins, and orange juice) in your diet.
How to take the Medicine
Consumption Info Drinking alcohol can increase certain side effects of hydrochlorothiazide. Avoid becoming overheated or dehydrated during exercise and in hot weather. Follow your doctor's instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough.
Drug quanitty Usual Adult Hydrochlorothiazide Dose for Edema: 25 to 100 mg orally as a single or divided dose. Usual Adult Dose for Hypertension: Initial dose: 25 mg orally once a day. Maintenance dose: May increase to 50 mg orally as a single or 2 divided doses. Usual Adult Hydrochlorothiazide Dose for Nephrocalcinosis: Initial: 25 mg orally once a day Maintenance dose: May increase to 50 mg twice a day Usual Adult Dose for Osteoporosis: Initial: 25 mg orally once a day Maintenance dose: May increase to 50 mg per day Usual Adult Hydrochlorothiazide Dose for Diabetes Insipidus: Initial: 50 mg orally once a day Maintenance dose: May increase to 100 mg per day
Drug Dose Hydrochlorothiazide comes as a tablet and liquid to take by mouth. It usually is taken once or twice a day. If you are to take it once a day, take it in the morning; if you are to take it twice a day, take it in the morning and in the late afternoon to avoid going to the bathroom during the night. Take this medication with a meal or snack. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take hydrochlorothiazide exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Hydrochlorothiazide controls high blood pressure but does not cure it. Continue to take hydrochlorothiazide even if you feel well. Do not stop taking hydrochlorothiazide without talking to your doctor.
Excess Drug Consumption Take the missed dose as soon as you remember it. However, if it is almost time for your next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
Forgot Drug Consumption Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
Stop Drug Consumption
Possible Side Effects
General Information sore throat with fever unusual bleeding or bruising severe skin rash with peeling skin difficulty breathing or swallowing
Common Drug Side Effects muscle weakness dizziness cramps thirst stomach pain nausea vomiting diarrhea loss of appetite headache hair loss
Rare Drug Side Effects
Very Rare Drug Side Effects
Drug Side Effects Symptoms
How to Store the Medicine
How to Store the Medicine Keep this medicine in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Do not allow the liquid to freeze. Throw away any medicine that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medicine.

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