Composition : MILRINONE-1MG/ML
Description : PRIMACOR INJ - 10 ML
Route Of Administration : PARENTERAL
Pack : 1
Out of stock
Composition : MILRINONE-1MG/ML
Description : PRIMACOR INJ - 10 ML
Route Of Administration : PARENTERAL
Pack : 1

Drug Ingredient Information



Information for patients
Drug Information Suddenly Serious Symptoms of Heart Failure Milrinone is a vasodilator that works by relaxing the muscles in your blood vessels to help them dilate (widen). This lowers blood pressure and allows blood to flow more easily through your veins and arteries.Milrinone is used as a short-term treatment for treat life-threatening heart failure.Milrinone may also be used for other purposes not listed in this medication guide.
Drug Alert
Alert Whether given orally or by continuous or intermittent intravenous infusion,milrinone has not been shown to be safe or effective in the longer (greater than 48 hours) treatment of patients with heart failure. In a multicenter trial of 1088 patients with Class III and IV heart failure, long-term oral treatment with milrinone was associated with no improvement in symptoms and an increased risk of hospitalization and death. In this study, patients with Class IV symptoms appeared to be at particular risk of life-threatening cardiovascular reactions. There is no evidence that milrinone given by long-term continuous or intermittent infusion does not carry a similar risk.The use of milrinone both intravenously and orally has been associated with increased frequency of ventricular arrhythmias, including nonsustained ventricular tachycardia. Long-term oral use has been associated with an increased risk of sudden death. Hence, patients receiving milrinone should be observed closely with the use of continuous electrocardiographic monitoring to allow the prompt detection and management of ventricular arrhythmias.
Before Consuming the Medicine
Avoid Drug You should not receive this medication if you are allergic to milrinone, or if you have recently had a heart attack.
Drug Special Care If possible before you receive milrinone, tell your doctor if you have a heart rhythm disorder or low levels of potassium in your blood (hypokalemia). In an emergency situation, it may not be possible before you are treated with milrinone to tell your caregivers if you are pregnant or breast-feeding. However, make sure any doctor caring for your pregnancy or your baby knows that you have received this medication.
Drug Drug Interactions digoxin (digitalis, Lanoxin, Lanoxicaps); or diuretic (water pill). This list is not complete and there may be other drugs that can interact with milrinone. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.
Drug Pregnancy Interaction It is not known whether milrinone is harmful to an unborn baby. Before taking this medication, tell your doctor if you are pregnant or plan to become pregnant during treatment.
Drug Breast feeding Interaction It is not known whether milrinone passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
Drug Machinery Interaction
Drug More Information Follow your doctor's instructions about any restrictions on food, beverages, or activity after your treatment with milrinone.
How to take the Medicine
Consumption Info
Drug quanitty 50 mcg/kg: Administer slowly over 10 minutes
Drug Dose Milrinone is given as an injection through a needle placed into a vein. You will receive this injection in a clinic or hospital setting. Milrinone is usually given around-the-clock for up to 48 hours. Your heart rate and blood pressure will be constantly monitored while you are being treated with milrinone. Your kidney function and electrolytes may also need to be checked with blood tests.
Excess Drug Consumption Tell your caregivers right away if you think you have received too much of this medicine. Overdose can cause severe dizziness or fainting.
Forgot Drug Consumption Since milrinone is given by a healthcare professional, you are not likely to miss a dose.
Stop Drug Consumption
Possible Side Effects
General Information headache; tremors; or easy bruising or bleeding.
Common Drug Side Effects chest pain; feeling like you might pass out; bronchospasm (wheezing, chest tightness, trouble breathing); or low potassium (confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling).
Rare Drug Side Effects
Very Rare Drug Side Effects
Drug Side Effects Symptoms
How to Store the Medicine
How to Store the Medicine Avoid excessive heat. Protect from freezing. It is recommended that the Flexible Containers be stored at room temperature, 25° C (77° F), however, brief exposure up to 40° C (104° F) does not adversely affect the product.

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