| Information for
patients
|
| Drug Information |
This medication is used in women who are pregnant with a single baby, and who have delivered a baby too early (preterm) in the past. It is used to help lower the risk of having a preterm baby again. Hydroxyprogesterone is a man-made form of a female hormone (progestin). It is not known how it works to prevent preterm labor.
This medication is not intended to prevent preterm birth in women pregnant with more than one baby (such as twins, triplets). It is also not intended to stop active preterm labor. |
| Drug Alert |
| Alert |
Dosing
Administer intramuscularly at a dose of 250 mg (1 mL) once weekly (every 7 days) by a healthcare provider
Begin treatment between 16 weeks, 0 days and 20 weeks, 6 days of gestation
Continue administration once weekly until week 37 (through 36 weeks, 6 days) of gestation or delivery, whichever occurs first
Preparation and Administration
Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit. Makena (hydroxyprogesterone caproate injection) is a clear, yellow solution. Do not use if solid particles appear or if the solution is cloudy.
Instructions for administration:
Clean the vial top with an alcohol swab before use.
Draw up 1 mL of drug into a 3 mL syringe with an 18 gauge needle.
Change the needle to a 21 gauge 1½ inch needle.
After preparing the skin, inject in the upper outer quadrant of the gluteus maximus. The solution is viscous and oily. Slow injection (over one minute or longer) is recommended.
Applying pressure to the injection site may minimize bruising and swelling. |
| Before Consuming
the Medicine
|
| Avoid Drug |
Before using hydroxyprogesterone, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. |
| Drug Special Care |
Before using this medication, tell your doctor or pharmacist your medical history, especially of: asthma, blood clots or other blood clotting problems, cancer (especially of the breast or other female organs), depression, diabetes, severe headaches/migraines, heart problems, high blood pressure, kidney problems, liver problems, seizure disorder, unusual vaginal bleeding, yellowing eyes/skin (jaundice) during pregnancy.
If you have diabetes, this medication may make it harder to control your blood sugar. Check your blood sugar level regularly as directed and share the results with your doctor. Tell your doctor right away if you have symptoms of high blood sugar, such as increased thirst and urination. Your doctor may need to adjust your diabetes medication or diet.
Tell your doctor if you will be having surgery or will be confined to a chair or bed for a long time (such as a long plane flight). You may need to take special precautions.
Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). |
| Drug Drug Interactions |
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval. |
| Drug Pregnancy Interaction |
This medication is used to prevent preterm birth during pregnancy. Discuss the risks and benefits with your doctor. |
| Drug Breast feeding Interaction |
This drug may pass into breast milk. However, it is not used after 37 weeks of pregnancy, or after delivery. Consult your doctor before breast-feeding. |
| Drug Machinery Interaction |
no data available |
| Drug More Information |
no data available |
| How to take the
Medicine
|
| Consumption Info |
no data available |
| Drug quanitty |
no data available |
| Drug Dose |
Read the Patient Information Leaflet if available from your pharmacist before you start using hydroxyprogesterone and each time you get a refill. If you have any questions, ask your doctor or pharmacist.
This medication is given by injection into your hip area (upper outer area of the buttocks) by a health care professional, usually once a week (every 7 days) or as directed by your doctor. You will start receiving injections any time from 16 to 20 weeks of your pregnancy. You will continue to receive injections once a week until week 37 of your pregnancy or when your baby is delivered, whichever happens first.
Use this medication regularly to get the most benefit from it. |
| Excess Drug Consumption |
If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call the US National Poison Hotline at 1-800-222-1222. Canada residents can call a provincial poison control center.
NOTES: Keep all regular medical and laboratory appointments. |
| Forgot Drug Consumption |
For the best possible benefit, it is important to receive each scheduled dose of this medication as directed. If you miss a dose, contact your doctor immediately to establish a new dosing schedule. |
| Stop Drug Consumption |
do not stop the medicine untill adviced by your physician |
| Possible Side
Effects
|
| General Information |
Pain, swelling, itching, bruising, or a lump at the injection site may occur. Nausea or diarrhea may also occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. |
| Common Drug Side Effects |
including: dark urine, mental/mood changes (such as depression, nervousness), persistent nausea/vomiting, stomach/abdominal pain, unusual vaginal bleeding, yellowing eyes/skin. |
| Rare Drug Side Effects |
chest/jaw/left arm pain, confusion, pain/swelling/redness/warmth in the leg, slurred speech, sudden shortness of breath, sudden vision changes (such as partial/complete blindness), weakness on one side of the body. |
| Very Rare Drug Side Effects |
no data available |
| Drug Side Effects Symptoms |
serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. |
| How to Store the
Medicine
|
| How to Store the Medicine |
Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.
Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company. |
Sign In
Create New Account