PROTERA I CAPSULE

Manufacturer : LUP-LUPIN LABORATORIES
Composition : PANTOPRAZOLE-40MG+ITOPRIDE HYDROCHLORIDE-150MG
Dose Form : CAPSULE
Description : PROTERA -I CAP
Route Of Administration : ORAL
Pack : 10
In stock
SKU
PRO0079
₹213.30
Manufacturer : LUP-LUPIN LABORATORIES
Composition : PANTOPRAZOLE-40MG+ITOPRIDE HYDROCHLORIDE-150MG
Dose Form : CAPSULE
Description : PROTERA -I CAP
Route Of Administration : ORAL
Pack : 10

Drug Ingredient Information

PANTOPRAZOLE-40MG+ITOPRIDE HYDROCHLORIDE-150MG

PANTOPRAZOLE

Information for patients
Drug Information Pantoprazole is used to treat certain stomach and esophagus problems (such as acid reflux). It works by decreasing the amount of acid your stomach makes. This medication relieves symptoms such as heartburn, difficulty swallowing, and persistent cough. It helps heal acid damage to the stomach and esophagus, helps prevent ulcers, and may help prevent cancer of the esophagus. Pantoprazole belongs to a class of drugs known as proton pump inhibitors (PPIs). This section contains uses of this drug that are not listed in the approved US professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional. This medication may also be used to treat and prevent stomach and intestinal ulcers.
Drug Alert
Alert
Before Consuming the Medicine
Avoid Drug Before taking pantoprazole, tell your doctor or pharmacist if you are allergic to it; or to similar drugs (such as lansoprazole, omeprazole); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Drug Special Care Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease. Some symptoms may actually be signs of a more serious condition. Tell your doctor immediately if you have: heartburn with lightheadedness/sweating/dizziness, chest pain or shoulder pain (especially with trouble breathing, sweating, lightheadedness, pain spreading to arms/jaw/neck/shoulders), unexplained weight loss. Proton pump inhibitors (such as pantoprazole) may increase your risk for bone fractures, especially with longer use, higher doses, and in older adults. Talk with your doctor or pharmacist about ways to prevent bone loss/fracture, such as by taking calcium (such as calcium citrate) and vitamin D supplements. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
Drug Drug Interactions Before taking pantoprazole, tell your doctor if you are using any of the following drugs: ampicillin (Omnipen, Principen); atazanavir (Reyataz); a blood thinner such as warfarin (Coumadin); clopidogrel (Plavix); ketoconazole (Nizoral); or iron (Feosol, Mol-Iron, Fergon, Femiron, others). This list is not complete and there may be other drugs that can interact with pantoprazole. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
Drug Pregnancy Interaction During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.
Drug Breast feeding Interaction This medication passes into breast milk. Consult your doctor before breast-feeding.
Drug Machinery Interaction
Drug More Information Follow your doctor's instructions about any restrictions on food, beverages, or activity while you are using pantoprazole.
How to take the Medicine
Consumption Info
Drug quanitty
Drug Dose Read the Patient Information Leaflet if available from your pharmacist before you start taking pantoprazole and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Take this medication by mouth as directed by your doctor, usually once daily. Dosage and length of treatment are based on your medical condition and response to treatment. If you are taking the tablets, you may take them with or without food. Swallow the tablets whole. Do not split, crush, or chew the medication. Doing so may destroy the drug. If you are taking the granules, take your dose 30 minutes before a meal. To take it by mouth, open the packet and mix the granules in applesauce or apple juice. Do not mix with other foods or liquids. Do not crush or chew the granules. Sprinkle the granules on 1 teaspoon (5 milliliters) of applesauce and swallow all of the mixture right away (within 10 minutes). Follow with sips of water. Or you can mix the granules with 1 teaspoon (5 milliliters) of apple juice in a small cup, stir for 5 seconds, and swallow all of the mixture right away. To make sure you take the entire dose, rinse the cup once or twice with apple juice to mix any remaining granules, and swallow the juice. Do not prepare the mixture ahead of time for later use. If you are giving the granules through a tube into the stomach (nasogastric or gastric tube), ask your health care professional for detailed instructions on how to properly mix and give it. If needed, antacids may be taken along with this medication. If you are also taking sucralfate, take pantoprazole at least 30 minutes before sucralfate. Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day. Continue to take this medication for the prescribed length of treatment even if you are feeling better. Tell your doctor if your condition persists or worsens.
Excess Drug Consumption Seek emergency medical attention if you think you have used too much of this medicine. An overdose of pantoprazole is not expected to produce life-threatening symptoms.
Forgot Drug Consumption If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
Stop Drug Consumption
Possible Side Effects
General Information including: symptoms of a low magnesium blood level (such as unusually fast/slow/irregular heartbeat, persistent muscle spasms, seizures).
Common Drug Side Effects serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
Rare Drug Side Effects
Very Rare Drug Side Effects
Drug Side Effects Symptoms
How to Store the Medicine
How to Store the Medicine Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

ITOPRIDE HYDROCHLORIDE

Information for patients
Drug Information Itopride (INN, trade name Ganaton) is a prokinetic benzamide derivative. These drugs inhibit dopamine and have a gastrokinetic effect. Itopride is indicated for the treatment of functional dyspepsia and other gastrointestinal conditions.
Drug Alert
Alert
Before Consuming the Medicine
Avoid Drug contraindicated: Known hypersensitivity to itopride hydrochloride or any of the excipients. Patients in whom an increase in gastrointestinal motility could be harmful eg, gastrointestinal hemorrhage, mechanical obstruction or perforation.
Drug Special Care Use in children: Safety of itopride in children <16 years has not been established. Use in the elderly: In general, appropriate caution should be exercised in the administration and monitoring of itopride hydrochloride in elderly patients reflecting the greater frequency of decreased hepatic, renal function and of concomitant disease or other drug therapy.
Drug Drug Interactions Metabolic interactions are not expected since itopride is primarily metabolized by flavine monooxygenase and not by CYP450. No changes in protein-binding have been seen with co-administration of warfarin, diazepam, diclofenac sodium, ticlopidine hydrochloride, nifedipine and nicardipine hydrochloride. Since itopride has gastrokinetic effects it could influence the absorption of concomitantly orally administered drugs. Particular caution should be taken with drugs with a narrow therapeutic index, sustained-release or enteric-coated formulations. Antiulcer drugs eg, cimetidine, ranitidine, teprenone and cetraxate do not affect the prokinetic action of itopride. Anticholinergic drugs may reduce the action of itopride.
Drug Pregnancy Interaction Itopride hydrochloride enhances the action of acetylcholine and may produce cholinergic side effects. Data on long-term use are not available. Use in pregnancy: There are no adequate and well-controlled studies in pregnant women. Therefore, itopride hydrochloride should not be used during pregnancy unless the benefits outweigh the potential risks. Labor and Delivery: There are no known effects of itopride hydrochloride on labor or delivery.
Drug Breast feeding Interaction Use in lactation: Because itopride is excreted in milk in rats, and because of the potential for adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or discontinue the drug, taking into account the importance of the drug to the mother.
Drug Machinery Interaction
Drug More Information indications: Treatment of gastrointestinal symptoms of functional, non-ulcer dyspepsia (chronic gastritis) ie, sensation of bloating, early satiety, upper abdominal pain or discomfort, anorexia, heartburn, nausea and vomiting.
How to take the Medicine
Consumption Info Mechanism of Action: Itopride hydrochloride activates gastrointestinal propulsive motility due to its dopamine D2 antagonizing activity and acetylcholinesterase inhibitory activity. Itopride activates acetylcholine release and inhibits degradation. Pharmacodynamics: Itopride hydrochloride also has antiemetic action through interaction with D2 receptors located in the chemoreceptor trigger zone. This was demonstrated by dose-dependent inhibition of apomorphine-induced vomiting in dogs. In conscious dogs, itopride hydrochloride activates propulsive gastric motility through dopamine D2 receptor antagonistic actions and dose-dependent inhibition of acetylcholinesterase. Itopride hydrochloride has been shown to accelerate gastric emptying in humans, dogs and rats. In single-dose studies in dogs, itopride hydrochloride was shown to promote gastric emptying. The action of itopride hydrochloride is highly specific for the upper gastrointestinal tract. It does not affect serum gastrin levels.
Drug quanitty Recommended Dose: 50 mg daily (150-mg tab taken orally 3 times a day before meals). The dose may be reduced according to the patient's age and symptoms (see Precautions). Duration of Treatment: In clinical studies, itopride has been administered up to 8 weeks.
Drug Dose
Excess Drug Consumption There have been no reported cases of overdose in humans. In case of excessive overdose, the usual measures of gastric lavage and symptomatic therapy should be applied.
Forgot Drug Consumption
Stop Drug Consumption
Possible Side Effects
General Information
Common Drug Side Effects Diarrhea, constipation, headache, abdominal pain, irritated feeling and dizziness.
Rare Drug Side Effects Genitourinary - Spontaneous milk secretion and breast enlargement in male. Miscellaneous - Decrease in white blood cells.
Very Rare Drug Side Effects
Drug Side Effects Symptoms
How to Store the Medicine
How to Store the Medicine Store below 30°C (86°F). Protect from light and moisture.

Substitute Drugs

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