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About CALCIUM CARBONATE+CALCITRIOL+ZINC SULFATE

CALCIUM CARBONATE+CALCITRIOL+ZINC SULFATE belongs to the class of ‘Multi-minerals’ primarily used to treat low blood calcium levels (hypocalcaemia) in patients undergoing dialysis for chronic renal failure. CALCIUM CARBONATE+CALCITRIOL+ZINC SULFATE effectively treats various conditions caused by low calcium levels in the body, such as osteoporosis (weak and brittle bones), osteomalacia/rickets (weak bones), and hypoparathyroidism (low levels of parathyroid hormone). CALCIUM CARBONATE+CALCITRIOL+ZINC SULFATE is also indicated in the treatment of psoriasis (a skin disease that causes itchy scaly patches), hypocalcaemia (low calcium levels in the blood) and hypomagnesaemia (low levels of magnesium in the blood) after small bowel resection. CALCIUM CARBONATE+CALCITRIOL+ZINC SULFATE can also be given to pregnant, nursing, and postmenopausal women to get enough calcium. Additionally, CALCIUM CARBONATE+CALCITRIOL+ZINC SULFATE is used to treat hyperparathyroidism (overactive parathyroid glands) and metabolic bone disease in people with chronic kidney disease, surgery, or other conditions.

CALCIUM CARBONATE+CALCITRIOL+ZINC SULFATE consists of three medicines, namely: Calcium (mineral), Calcitriol (Vitamin D3), and Zinc sulfate (mineral). Calcium is a mineral that is used to prevent or treat a calcium deficiency. It provides essential nutrients to maintain bone formation and maintenance. Calcitriol is a synthetic version of Vitamin D3 and treats calcium deficiency with hypoparathyroidism (the parathyroid gland's decreased activity) and metabolic bone diseases in people with chronic kidney failure. It raises Vitamin D levels and thereby increases calcium levels in the blood. This helps in improving the absorption rate of calcium from the intestine. Zinc sulfate is a mineral that has an essential role in bone health. Zinc helps to stimulate osteoblastic bone formation and mineralization.

Take CALCIUM CARBONATE+CALCITRIOL+ZINC SULFATE as recommended by your doctor. In some cases, CALCIUM CARBONATE+CALCITRIOL+ZINC SULFATE can cause side effects like constipation or stomach upset, nausea, vomiting, loss of appetite, weakness, tiredness, fast or pounding heartbeat, bone/muscle pain, and headache. Most of these side effects of CALCIUM CARBONATE+CALCITRIOL+ZINC SULFATE do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.

If you are known to be allergic to CALCIUM CARBONATE+CALCITRIOL+ZINC SULFATE or its inactive components, please inform your doctor. Pregnant or breastfeeding women should consult their doctor before taking CALCIUM CARBONATE+CALCITRIOL+ZINC SULFATE. Higher doses of Vitamin D than the recommended daily dose should be used in pregnant women only when the doctor advises. CALCIUM CARBONATE+CALCITRIOL+ZINC SULFATE may pass into the breast milk. Hence breastfeeding mothers need to seek medical advice before starting CALCIUM CARBONATE+CALCITRIOL+ZINC SULFATE. Do not take CALCIUM CARBONATE+CALCITRIOL+ZINC SULFATE if you have renal failure, Hypervitaminosis D(excess of vitamin D), Nephrolithiasis/nephrocalcinosis (kidney stones). Inform your doctor if you have any heart/kidney/liver/blood vessel diseases, kidney stones, sarcoidosis (growth of inflammatory cells in different parts of the body), Crohn's disease (inflammatory bowel disease), Whipple's disease (bacterial infection affecting joints and digestive system), low levels of bile, and phosphate imbalance. CALCIUM CARBONATE+CALCITRIOL+ZINC SULFATE may contain sugar or sorbitol; hence caution should be taken to have sugar intolerance, diabetes, and phenylketonuria (increased levels of an amino acid called phenylalanine).

Uses of CALCIUM CARBONATE+CALCITRIOL+ZINC SULFATE

Osteoporosis, Postmenopausal osteoporosis, Osteomalacia, Rickets, Calcium deficiency, Tetany and Hypoparathyroidism

Medicinal Benefits

CALCIUM CARBONATE+CALCITRIOL+ZINC SULFATE is a combination of three drugs, namely; Calcium (mineral), Calcitriol (Vitamin D3), and Zinc sulfate (mineral) used to treat low blood calcium levels and various associated conditions caused by low calcium levels in the body, such as osteoporosis (weak and brittle bones), osteomalacia/rickets (weak bones), hypoparathyroidism (low levels of parathyroid hormone), and tetany (a muscle disease with low blood calcium levels). Calcium is a mineral and prevents or treats calcium deficiency. It helps to maintain bone and teeth health. Calcitriol, a synthetic form of Vitamin D3, treats calcium deficiency with hypoparathyroidism (the parathyroid gland's decreased activity) and metabolic bone diseases in people with chronic kidney failure. Zinc sulfate is an important mineral in the normal growth and development of the skeletal system. It helps maintain bone density by increasing protein synthetase, which helps protect bone health.

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush, break or chew it. Oral Suspension/syrup: Shake the bottle well before each use. Take the recommended dose by mouth using the measuring cup/dosing syringe/dropper.

Storage

Store in a cool and dry place away from sunlight

Side Effects of CALCIUM CARBONATE+CALCITRIOL+ZINC SULFATE

  • Constipation
  • Stomach pain
  • Fast or pounding heartbeat
  • Bone or muscle pain

In-Depth Precautions and Warning

Drug Warnings

Please inform your doctor if you are allergic to CALCIUM CARBONATE+CALCITRIOL+ZINC SULFATE or any other medicines. If you are pregnant or planning to become pregnant, it is advised to inform your doctor before using CALCIUM CARBONATE+CALCITRIOL+ZINC SULFATE. Higher doses of Vitamin D than the recommended daily dose should be used in pregnant women only when the doctor advises. Calcitriol in higher doses may harm the fetus. CALCIUM CARBONATE+CALCITRIOL+ZINC SULFATE may pass into the breast milk; hence consult your doctor before taking CALCIUM CARBONATE+CALCITRIOL+ZINC SULFATE if you are a breastfeeding mother. CALCIUM CARBONATE+CALCITRIOL+ZINC SULFATE should be used with caution in children and only if advised by a doctor. Calcitriol in CALCIUM CARBONATE+CALCITRIOL+ZINC SULFATE can affect growth in children. Inform your doctor if your child is not growing normally while using the CALCIUM CARBONATE+CALCITRIOL+ZINC SULFATE. CALCIUM CARBONATE+CALCITRIOL+ZINC SULFATE is not recommended if you have hypercalcemia (high calcium levels), metastatic calcification (extra deposits of calcium in the body), hypervitaminosis D (high vitamin D levels), and malabsorption syndrome (difficulty absorbing nutrition from food).

Drug Interactions

Drug-Drug Interactions: CALCIUM CARBONATE+CALCITRIOL+ZINC SULFATE may interact with calcium supplements (ergocalciferol, cholecalciferol), steroid medicines (hydrocortisone, prednisolone), central nervous system stimulants (dextroamphetamine, amphetamine), anti-depressants (duloxetine), minerals (ferrous sulfate), anti-ulcer drugs (ranitidine), synthetic thyroid hormone (levothyroxine), painkillers (aspirin), antibiotics (doxycycline, minocycline), quinolone antibiotics (ciprofloxacin, levofloxacin), weight-loss drugs (orlistat), and anti-cancer medication (estramustine).

Drug-Food Interactions: Avoid or reduce the intake of caffeine, soft drinks, and alcohol that inhibit calcium absorption.

Drug-Disease Interactions: CALCIUM CARBONATE+CALCITRIOL+ZINC SULFATE is contraindicated in hypercalcemia (high calcium level in blood), hypervitaminosis D (high vitamin D level in the body), Vitamin D toxicity, malabsorption syndrome, heart/kidney/liver/blood vessel diseases, kidney stones.

Drug-Drug Interactions Checker List:

  • CHOLECALCIFEROL
  • ERGOCALCIFEROL
  • HYDROCORTISONE
  • PREDNISOLONE
  • DEXTROAMPHETAMINE
  • AMPHETAMINE
  • DULOXETINE
  • FERROUS SULPHATE
  • RANITIDINE
  • LEVOTHYROXINE
  • ASPIRIN
  • DOXYCYCLINE
  • MINOCYCLINE
  • CIPROFLOXACIN
  • LEVOFLOXACIN
  • ORLISTAT
  • ESTRAMUSTINE
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      Drinking alcohol can affect calcium absorption; hence it is advised to limit the alcohol intake while using CALCIUM CARBONATE+CALCITRIOL+ZINC SULFATE.

    • Safety Warning

      Pregnancy

      caution

      During pregnancy, use higher doses of CALCIUM CARBONATE+CALCITRIOL+ZINC SULFATE than the daily dietary allowance only when the doctor advises. Calcitriol in higher doses may harm the fetus. Your doctor will weigh the potential risks and benefits before advising CALCIUM CARBONATE+CALCITRIOL+ZINC SULFATE.

    • Safety Warning

      Breast Feeding

      caution

      Consult your doctor before taking CALCIUM CARBONATE+CALCITRIOL+ZINC SULFATE if you are breastfeeding. CALCIUM CARBONATE+CALCITRIOL+ZINC SULFATE can pass into the breast milk. If CALCIUM CARBONATE+CALCITRIOL+ZINC SULFATE is used during breastfeeding, please monitor the mother and the infant's serum calcium levels.

    • Safety Warning

      Driving

      caution

      It does not impact your ability to drive or operate machinery.

    • Safety Warning

      Liver

      caution

      Let your doctor know if you have any history of liver diseases before taking CALCIUM CARBONATE+CALCITRIOL+ZINC SULFATE. Hepatic impairment/liver disease can alter certain Vitamin D forms' metabolic and therapeutic activity.

    • Safety Warning

      Kidney

      caution

      It is advised to seek a doctor's advice before starting CALCIUM CARBONATE+CALCITRIOL+ZINC SULFATE if you have kidney diseases like kidney stones or undergoing dialysis. Calcitriol in CALCIUM CARBONATE+CALCITRIOL+ZINC SULFATE increases inorganic phosphate levels in serum; hence caution should be taken in patients undergoing dialysis to maintain adequate phosphorus levels and avoid ectopic calcification (calcium deposition).

    • Safety Warning

      Children

      caution

      Caution should be excercised, and it should be used only if the doctor recommends it.

    Habit Forming

    No

    Diet & Lifestyle Advise

    •  
    • Include dairy products like milk, yoghurt, cheese, or milk-based custard in your regular diet.
    • Eat a serving of broccoli, cabbage, bok choy, spinach, and other green leafy vegetables.
    • Snack on calcium-rich nuts like Brazil nuts or almonds.
    • Sprinkle sesame seeds over your food, vegetables, and salads. Sesame seeds are high in calcium.
    • Avoid or reduce the intake of caffeine, soft drinks, and alcohol that inhibit calcium absorption.
    • Replace the meat with tofu or tempeh for extra calcium in your food.

    Special Advise

    • Clinical monitoring of serum electrolyte concentrations and cardiac function is recommended.
    • A low phosphate diet is recommended to control serum phosphorus levels in dialysis patients. 

    Patients Concern

    Disease/Condition Glossary

    Osteoporosis: Osteoporosis is a bone disease that weakens and brittle bones by decreasing bone density.  As bones become less dense, they weaken and are more likely to break. Breaking a bone is a serious complication of osteoporosis, especially in older patients. Women are much more likely to develop osteoporosis than men. Signs and symptoms include back pain caused by a fractured or collapsed vertebra, loss of height over time, a stooped posture, and a bone that breaks much more easily than expected.

    Osteomalacia/Rickets: A bone disease caused by softening and weakening bones in children due to inadequate vitamin D. Adults can experience a similar condition known as osteomalacia. It causes bone pain, poor growth, and weak bones, leading to bone deformities.

    Tetany: A disease condition due to low calcium levels (hypocalcemia) in the body that causes cramps and spasms in the hands, feet, and larynx (voice box).

    Hypoparathyroidism: It is a disease characterized by low levels of parathyroid hormone. This can cause low calcium levels and trigger tetany.

    FAQs

    How does CALCIUM CARBONATE+CALCITRIOL+ZINC SULFATE work?

    CALCIUM CARBONATE+CALCITRIOL+ZINC SULFATE is a combination of three medicines: Calcitriol, Calcium, and Zinc sulfate. Calcitriol helps your body absorb Calcium Carbonate and supports the muscles needed to avoid falls. Calcium and Zinc sulfate help build and maintain bones. Collectively, CALCIUM CARBONATE+CALCITRIOL+ZINC SULFATE used to treat osteoporosis (weak and brittle bones), osteomalacia/rickets (weak bones), hypoparathyroidism (low levels of parathyroid hormone), and tetany (a muscle disease with low blood calcium levels).

    Can I take CALCIUM CARBONATE+CALCITRIOL+ZINC SULFATE if I suffer from hypercalcemia (high levels of calcium in the blood)?

    CALCIUM CARBONATE+CALCITRIOL+ZINC SULFATE is used to increase low levels of calcium in the body. Hence it is not advised to use CALCIUM CARBONATE+CALCITRIOL+ZINC SULFATE during hypercalcemia since it causes an overdose of calcium leading to kidney stones and other effects.

    Does CALCIUM CARBONATE+CALCITRIOL+ZINC SULFATE cause kidney stones?

    CALCIUM CARBONATE+CALCITRIOL+ZINC SULFATE can cause kidney stones due to excess calcium deposition when used for a prolonged period. Please consult your doctor before taking CALCIUM CARBONATE+CALCITRIOL+ZINC SULFATE as a daily supplement if you have kidney problems or kidney stones history.

    What are the common side effects of CALCIUM CARBONATE+CALCITRIOL+ZINC SULFATE?

    Common side effects of CALCIUM CARBONATE+CALCITRIOL+ZINC SULFATE include constipation, stomach pain, loss of appetite, fast or pounding heartbeat, and bone or muscle pain.

    In which conditions should I avoid taking CALCIUM CARBONATE+CALCITRIOL+ZINC SULFATE?

    Do not take it if you are allergic to CALCIUM CARBONATE+CALCITRIOL+ZINC SULFATE or other ingredients present in CALCIUM CARBONATE+CALCITRIOL+ZINC SULFATE. CALCIUM CARBONATE+CALCITRIOL+ZINC SULFATE is not recommended in hypercalcemia (high calcium levels), metastatic calcification (extra deposits of calcium in the body), hypervitaminosis D (high vitamin D levels), and malabsorption syndrome (difficulty absorbing nutrition from food), and renal failure.

    Available Medicines for

    CALCIUM CARBONATE+CALCITRIOL+ZINC SULFATE