About DEXTROMETHORPHAN+CHLORPHENIRAMINE+GUAIFENESIN+AMMONIUM CHLORIDE
DEXTROMETHORPHAN+CHLORPHENIRAMINE+GUAIFENESIN+AMMONIUM CHLORIDE belongs to a class of medications called ‘expectorants’ primarily used to treat cough. Coughing (dry or productive) is a body’s way of clearing irritants (like allergens, mucus, or smoke) from airways and preventing infection. There are two types of coughs, namely: Dry cough and chesty cough. A dry cough is tickly and doesn't produce any vicious or thick mucus, while a chesty cough (wet cough) means mucous or sputum is produced to help clear your airways.
DEXTROMETHORPHAN+CHLORPHENIRAMINE+GUAIFENESIN+AMMONIUM CHLORIDE contains four medicines namely: Dextromethorphan (cough suppressant), Chlorpheniramine (antihistamine/antiallergic), Guaifenesin (expectorant), and Ammonium chloride (irritative agent). Dextromethorphan belongs to the class of cough suppressants that works by blocking the transmission of nerve signals from the cough center in the brain to the muscles that produce cough thereby decreasing the urge to cough. Chlorpheniramine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, responsible for causing allergic reactions. It also provides relief from symptoms of allergic symptoms such as sneezing, running nose, watery eyes, itching, swelling, and congestion or stiffness. Guaifenesin and Ammonium chloride belongs to the class of irritants and expectorants that works by irritating the airways which increase the production of respiratory tract fluids and decrease the stickiness of mucus that can be coughed out easily. Thus, together DEXTROMETHORPHAN+CHLORPHENIRAMINE+GUAIFENESIN+AMMONIUM CHLORIDE helps in removing mucus from the airways and helps in easy breathing especially.
Take DEXTROMETHORPHAN+CHLORPHENIRAMINE+GUAIFENESIN+AMMONIUM CHLORIDE as prescribed. Your doctor will recommend you how often you take DEXTROMETHORPHAN+CHLORPHENIRAMINE+GUAIFENESIN+AMMONIUM CHLORIDE based on your medical condition. Some people may experience dry mouth, throat or nose, nausea, stomach upset, vomiting, drowsiness, headache, blurred vision, constipation, dizziness, restlessness, or nervousness. Most of these side effects of DEXTROMETHORPHAN+CHLORPHENIRAMINE+GUAIFENESIN+AMMONIUM CHLORIDE do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
If you are allergic to DEXTROMETHORPHAN+CHLORPHENIRAMINE+GUAIFENESIN+AMMONIUM CHLORIDE or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using DEXTROMETHORPHAN+CHLORPHENIRAMINE+GUAIFENESIN+AMMONIUM CHLORIDE. DEXTROMETHORPHAN+CHLORPHENIRAMINE+GUAIFENESIN+AMMONIUM CHLORIDE is not recommended for children below 12 years of age. Drink plenty of fluids while taking DEXTROMETHORPHAN+CHLORPHENIRAMINE+GUAIFENESIN+AMMONIUM CHLORIDE to loosen mucus. If you have high blood pressure, fits, glaucoma, hyperthyroidism (overactive thyroid), chronic bronchitis, asthma, cough with mucus, cough caused by smoking, chronic bronchitis or emphysema (a lung condition causing shortness of breath), chronic obstructive pulmonary disease (COPD), blockage in stomach or intestines, phenylketonuria (a birth defect that causes accumulation of amino acid, phenylalanine in the body), enlarged prostate, pheochromocytoma (tumor in the adrenal glands), kidney, liver, lung, heart or urinary problems, inform your doctor before taking DEXTROMETHORPHAN+CHLORPHENIRAMINE+GUAIFENESIN+AMMONIUM CHLORIDE.
Uses of DEXTROMETHORPHAN+CHLORPHENIRAMINE+GUAIFENESIN+AMMONIUM CHLORIDE
Cough
Medicinal Benefits
DEXTROMETHORPHAN+CHLORPHENIRAMINE+GUAIFENESIN+AMMONIUM CHLORIDE is a combination of four drugs, namely: Dextromethorphan, Chlorpheniramine, Guaifenesin, and Ammonium chloride. Dextromethorphan belongs to the class of cough suppressants that decrease the urge to cough. Chlorpheniramine is an antihistamine (anti-allergic drug) that provides relief from symptoms of allergy such as sneezing, stuffy/runny nose, watery eyes, itching, swelling, and congestion or stiffness. Guaifenesin and Ammonium chloride belongs to the class of irritants and expectorants that works by irritating the airways which increase the production of respiratory tract fluids and decrease the stickiness of mucus that can be coughed out easily. Together DEXTROMETHORPHAN+CHLORPHENIRAMINE+GUAIFENESIN+AMMONIUM CHLORIDE helps in clearing the respiratory tract from cough for easy breathing.
Directions for Use
Storage
Side Effects of DEXTROMETHORPHAN+CHLORPHENIRAMINE+GUAIFENESIN+AMMONIUM CHLORIDE
- Dry mouth, throat or nose
- Nausea
- Vomiting
- Stomach upset
- Constipation
- Drowsiness
- Headache
- Blurred vision
- Dizziness
- Restlessness or nervousness
In-Depth Precautions and Warning
Drug Warnings
If you are allergic to DEXTROMETHORPHAN+CHLORPHENIRAMINE+GUAIFENESIN+AMMONIUM CHLORIDE or pregnant or breastfeeding, then it is advised to inform your doctor before using DEXTROMETHORPHAN+CHLORPHENIRAMINE+GUAIFENESIN+AMMONIUM CHLORIDE. DEXTROMETHORPHAN+CHLORPHENIRAMINE+GUAIFENESIN+AMMONIUM CHLORIDE is not recommended for children below 12 years of age. If you are about to undergo any medical tests or surgery, please inform your doctor that you are taking DEXTROMETHORPHAN+CHLORPHENIRAMINE+GUAIFENESIN+AMMONIUM CHLORIDE. Avoid using DEXTROMETHORPHAN+CHLORPHENIRAMINE+GUAIFENESIN+AMMONIUM CHLORIDE if you have taken medicines such as linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine, and methylene blue injection in the past 14 days. If you have high blood pressure, fits, glaucoma, hyperthyroidism (overactive thyroid), chronic bronchitis, asthma, cough with mucus, cough caused by smoking, chronic bronchitis or emphysema (a lung condition causing shortness of breath), chronic obstructive pulmonary disease (COPD), blockage in stomach or intestines, phenylketonuria (a congenital disability that causes accumulation of amino acid, phenylalanine in the body), enlarged prostate, pheochromocytoma (tumor in the adrenal glands), kidney, liver, lung, heart or urinary problems, inform your doctor before taking DEXTROMETHORPHAN+CHLORPHENIRAMINE+GUAIFENESIN+AMMONIUM CHLORIDE.
Drug Interactions
Drug-Drug Interaction: DEXTROMETHORPHAN+CHLORPHENIRAMINE+GUAIFENESIN+AMMONIUM CHLORIDE may have interaction with anti-allergic drugs (diphenhydramine, cetirizine), antidepressants (duloxetine, sertraline, escitalopram), opioid painkiller (methadone), narcotic analgesics (hydrocodone, codeine), antipsychotics (haloperidol, quetiapine), antianxiety drug (alprazolam), medicines used to treat irregular heartbeats (quinidine, amiodarone), anticonvulsants (pregabalin) and a central nervous system stimulant (amphetamine).
Drug-Food Interaction: DEXTROMETHORPHAN+CHLORPHENIRAMINE+GUAIFENESIN+AMMONIUM CHLORIDE may interact with alcohol. Therefore, avoid consumption of alcohol with DEXTROMETHORPHAN+CHLORPHENIRAMINE+GUAIFENESIN+AMMONIUM CHLORIDE as it may increase the risk of adverse effects such as drowsiness, dizziness, or difficulty in concentrating.
Drug-Disease Interaction: If you have high blood pressure, fits, glaucoma, hyperthyroidism (overactive thyroid), chronic bronchitis, asthma, cough with mucus, cough caused by smoking, chronic bronchitis or emphysema (a lung condition causing shortness of breath), chronic obstructive pulmonary disease (COPD), blockage in stomach or intestines, phenylketonuria (a congenital disability that causes accumulation of amino acid, phenylalanine in the body), enlarged prostate, pheochromocytoma (tumor in the adrenal glands), kidney, liver, lung, heart or urinary problems, inform your doctor before taking DEXTROMETHORPHAN+CHLORPHENIRAMINE+GUAIFENESIN+AMMONIUM CHLORIDE.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeAvoid consumption of alcohol with DEXTROMETHORPHAN+CHLORPHENIRAMINE+GUAIFENESIN+AMMONIUM CHLORIDE as it may increase adverse effects. Please consult a doctor before consuming alcohol with DEXTROMETHORPHAN+CHLORPHENIRAMINE+GUAIFENESIN+AMMONIUM CHLORIDE.
Pregnancy
cautionThe safety of DEXTROMETHORPHAN+CHLORPHENIRAMINE+GUAIFENESIN+AMMONIUM CHLORIDE in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks benefits outweigh risks.
Breast Feeding
safe if prescribedDEXTROMETHORPHAN+CHLORPHENIRAMINE+GUAIFENESIN+AMMONIUM CHLORIDE is given to breastfeeding mothers only if the doctor thinks benefits are greater than risks.
Driving
cautionDEXTROMETHORPHAN+CHLORPHENIRAMINE+GUAIFENESIN+AMMONIUM CHLORIDE may impair thinking or cause blurred vision or dizziness in some people. Therefore, drive only if you are alert after taking DEXTROMETHORPHAN+CHLORPHENIRAMINE+GUAIFENESIN+AMMONIUM CHLORIDE.
Liver
cautionTake DEXTROMETHORPHAN+CHLORPHENIRAMINE+GUAIFENESIN+AMMONIUM CHLORIDE with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required if you have severe liver disease.
Kidney
cautionTake DEXTROMETHORPHAN+CHLORPHENIRAMINE+GUAIFENESIN+AMMONIUM CHLORIDE with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required in sever kidney disease.
Children
unsafeDEXTROMETHORPHAN+CHLORPHENIRAMINE+GUAIFENESIN+AMMONIUM CHLORIDE is not recommended for children below 12 years of age. Please consult a doctor if you have any concerns.
Habit Forming
Diet & Lifestyle Advise
- Avoid dairy products such as milk as it may increase mucus production. Also, avoid processed or refined foods to have relief from cough. Instead replace baked foods, fried foods, white bread, white pasta, French fries, sugary desserts and chips with green leafy vegetables.
- Drink plenty of fluids to avoid dry throat while you have a cough and loosen mucus.
- Avoid citrus fruits as it may worsen the cough. Eat fruits rich in water content such as pears, watermelon, peaches and pineapples.
Special Advise
- You are recommended to inform your doctor that you are taking DEXTROMETHORPHAN+CHLORPHENIRAMINE+GUAIFENESIN+AMMONIUM CHLORIDE before undergoing any medical tests or surgery.
- It is advised to stop the use of DEXTROMETHORPHAN+CHLORPHENIRAMINE+GUAIFENESIN+AMMONIUM CHLORIDE if your cough persists for more than 1 week and it reoccurs or is accompanied by hay fever, skin rash or persistent fever.
Patients Concern
Disease/Condition Glossary
Cough: Coughing is a body’s way of clearing irritants (like allergens, mucus, or smoke) from airways and preventing infection. Coughs may be dry or productive. A productive cough (wet cough) brings up sputum (phlegm, mucus, and other matter) from the lungs. Cough is commonly caused as a response to allergy or viral infection but coughing up mucus is possibly an indication of infection in the respiratory tract. If you are coughing thick, solid white mucus, you may have a bacterial infection in the airways. If the mucus is clear or light-colored, you may have allergies or a minor infection in the respiratory tract, and yellow or green mucus indicates a respiratory infection.
