Domperidone
About Domperidone
Domperidone is an antiemetic medicine. It is used to treat vomiting (being sick) in infants and children. Besides this, it also helps in the treatment of indigestion. In children, vomiting is a symptom of milk intolerance or food allergy.
Domperidone contains domperidone which is a dopamine antagonist. It works by blocking certain receptors like dopamine and serotonin which stimulate the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. It increases the upper gastrointestinal tract's motility and helps decrease stomach emptying time.
Domperidone cause dry mouth as a side effect in your child. If this side effect worsens, please consult your paediatrician. Domperidone should be given as advised by your doctor. Symptoms of nausea and vomiting may usually resolve within 3-4 days after taking Domperidone. However, if it does not resolve even after this, stop giving this medicine to your child and contact the paediatrician. Do not give more than the prescribed dose of Domperidone to the child. Domperidone can be given with or without food. The dose of the medicine will be decided by your pediatrician depending upon the type and severity of the infection.
Domperidone is intended for paediatric use only. Avoid giving Domperidone to your child if she/he is allergic to any of the components present in the formulation. Keep your doctor informed about your child’s health condition including his current medications and medical history to rule out any side effects/interactions. Before administration, inform your child’s doctor about liver and kidney disease.
Uses of Domperidone
• Nausea Relief: Domperidone helps alleviate nausea and vomiting in infants, making it easier for them to settle after feeding.
• Digestive Aid: Domperidone supports healthy digestion by reducing gut discomfort, which can be beneficial for babies experiencing colic or gas.
• Motion Sickness: Domperidone can be used to prevent or treat motion sickness in young children during travel.
Medicinal Benefits
Domperidone contains domperidone which is a dopamine antagonist. It works by blocking certain receptors like dopamine and serotonin which stimulate the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. It increases the upper gastrointestinal tract's motility and helps decrease stomach emptying time. If you're experiencing difficulty while nursing the child, your doctor may prescribe it if nothing else has helped.
Directions for Use
• Domperidone should be administered 15 to 30 minutes before meals, or as directed by the doctor. • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety. • Administer the prescribed dose to the child using the measuring cup/dosing syringe. • Shake well before use.
Storage
Side Effects of Domperidone
- Nausea
- Diarrhoea
- Stomach upset
- Indigestion
Drug Warnings
Avoid giving Domperidone to your child if she/he is allergic to any of the components present in the formulation. Keep your doctor informed about your child’s health condition, including his current medications and medical history, to rule out any side effects/interactions. Before administration, inform your child’s doctor about liver and kidney disease. Domperidone is intended for paediatric use only. Hence, avoid using it for the adult population and pregnant women.
Drug Interactions
Drug-Drug Interactions: Domperidone has interactions with antibiotics (azithromycin, erythromycin), anti-fungal (ketoconazole) and anti-viral/anti-HIV drugs (ritonavir).
Drug-Food Interactions: No interactions found/established.
Drug-Disease Interactions: Inform your doctor before administering Domperidone if your child has any history of kidney or liver disease.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
not applicable-
Pregnancy
not applicable-
Breast Feeding
not applicable-
Driving
not applicable-
Liver
cautionPlease consult your doctor if your child has a liver impairment or if you have any concerns regarding this.
Kidney
cautionPlease consult your doctor if your child has a kidney impairment or if you have any concerns regarding this.
Children
safe if prescribedDomperidone is safe for children above if prescribed by the doctor. The dose of the medicine will be decided by your paediatrician. Do not give more than the recommended dose to your child.
Habit Forming
Diet & Lifestyle Advise
- The child’s immune system is affected by stress and raises the risk of being sick. Hence try progressive muscle relaxation techniques to relieve stress.
- Sleeping for 7-9 hours each night can make your child stay fit and safe.
- Certain food items are known to cause vomiting in your child.
- Make your child drink more fluids to avoid dehydration.
Patients Concern
Disease/Condition Glossary
Vomiting is the forcible voluntary or involuntary emptying of stomach contents through the mouth. In short, vomiting is not a disease but a symptom of milk intolerance and food allergies. A receptor in our brain known as the chemoreceptor zone (CTZ) controls vomiting.
FAQs
Domperidone is used to treat vomiting.
Domperidone contains domperidone which is a dopamine antagonist. It works by blocking certain receptors like dopamine and serotonin which stimulate the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain.
If your child feels better, please consult your paediatrician before you stop giving Domperidone to your child.
