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About INSULIN HUMAN+ISOPHANE INSULIN

INSULIN HUMAN+ISOPHANE INSULIN is used for the treatment of both type 1 and type 2 diabetes mellitus. In Diabetes Mellitus Type 1, the body does not make enough insulin to control blood sugar levels. In Diabetes Mellitus type 2, either the body stops producing enough insulin (the hormone which helps to decrease sugar levels in the blood) or there is resistance to the action of insulin. As a result, insulin is produced in large amounts, but it cannot act on the organs of the body.

INSULIN HUMAN+ISOPHANE INSULIN is a combination of two drugs, namely: Insulin Human (a short-acting type of insulin) and Isophane Insulin (intermediate-acting). INSULIN HUMAN+ISOPHANE INSULIN suppresses the production of sugar in the liver and facilitates the reuptake of sugar in the fat and muscle cells, thereby INSULIN HUMAN+ISOPHANE INSULIN ensures rapid and consistent sugar control. 

You are advised to take INSULIN HUMAN+ISOPHANE INSULIN for as long as your doctor has prescribed it for you, depending on your medical conditions. In some cases, INSULIN HUMAN+ISOPHANE INSULIN may cause certain common side effects like an allergic reaction at the site of injection, hypoglycemia (low blood glucose level), itching, lipodystrophy (skin thickening or pits at the injection site), oedema (swelling), rashes, and weight gain. Most of these side effects of INSULIN HUMAN+ISOPHANE INSULIN do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Consult your doctor before taking INSULIN HUMAN+ISOPHANE INSULIN if you are pregnant or breastfeeding. INSULIN HUMAN+ISOPHANE INSULIN may cause drowsiness, so drive with caution. Avoid alcohol consumption along with INSULIN HUMAN+ISOPHANE INSULIN as it may cause unpleasant side effects. INSULIN HUMAN+ISOPHANE INSULIN should be given to children only if prescribed by the doctor. Keep your doctor informed about your health condition and medications to rule out any interactions. INSULIN HUMAN+ISOPHANE INSULIN has to be stored in the refrigerator between 2-8°C else its efficiency may be lost. Do not store in the freezer.

Uses of INSULIN HUMAN+ISOPHANE INSULIN

Diabetes (Type 1 diabetes mellitus, Type 2 diabetes mellitus).

Medicinal Benefits

INSULIN HUMAN+ISOPHANE INSULIN is a combination of two drugs, namely: Insulin Human (a short-acting type of insulin) and Isophane Insulin (intermediate-acting). INSULIN HUMAN+ISOPHANE INSULIN is used for the treatment of both type 1 and type 2 diabetes mellitus. INSULIN HUMAN+ISOPHANE INSULIN suppresses the production of sugar in the liver and facilitates the reuptake of sugar in the fat and muscle cells, thereby INSULIN HUMAN+ISOPHANE INSULIN ensures rapid and consistent sugar control.  INSULIN HUMAN+ISOPHANE INSULIN helps in improving the glycaemic control which in turn decreases the risk of progression of diabetes complications like damage of retina (retinopathy), damage of kidney (nephropathy), damage of nerve cells (neuropathy), delayed wound healing, and diabetic foot ulcer.

Directions for Use

INSULIN HUMAN+ISOPHANE INSULIN should be administered subcutaneously (in the upper thigh, abdomen, upper arm, or buttocks). It should never be administered intravenously or in the vein. If you are not well trained to self-administer INSULIN HUMAN+ISOPHANE INSULIN, ask a healthcare professional to administer it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of INSULIN HUMAN+ISOPHANE INSULIN

  • Allergic reaction at the site of injection
  • Hypoglycemia (low blood glucose level)
  • Itching
  • Lipodystrophy (skin thickening or pits at the injection site)
  • Oedema (swelling)
  • Rashes
  • Weight gain

In-Depth Precautions and Warning

Drug Warnings

Do not take INSULIN HUMAN+ISOPHANE INSULIN if you are allergic to any of the contents. Inform your doctor if you have hypoglycemia (low blood glucose levels), hypokalemia (low levels of potassium in the blood), heart, kidney or liver problems. Consult a doctor before taking INSULIN HUMAN+ISOPHANE INSULIN if you are pregnant or breastfeeding. INSULIN HUMAN+ISOPHANE INSULIN may cause dizziness, so drive only if you are alert. You are recommended not to consume alcohol as it may cause unpleasant side effects. Care should be taken when you are travelling across more than 2 time zones; your doctor may adjust your insulin schedule. 

Drug Interactions

Drug-Drug Interaction: INSULIN HUMAN+ISOPHANE INSULIN may interact with medicines such as pain killer (aspirin), antibiotic (ciprofloxacin), bronchodilators (albuterol, ipratropium), diuretic (furosemide), anti-hypertensive (metoprolol), anti-depressant (sertraline), oral hypoglycemic agents, monoamine oxidase inhibitors, anabolic steroids, glucocorticoids, thyroid hormones and sympathomimetics.

Drug-Food Interaction: Avoid consumption of alcohol along with INSULIN HUMAN+ISOPHANE INSULIN as it may lead to unpleasant side effects.

Drug-Disease Interaction: Inform your doctor if you have kidney disease, liver disease, low potassium level (hypokalaemia), and low blood sugar/glucose level (hypoglycemia).

Drug-Drug Interactions Checker List:

  • ASPIRIN
  • CIPROFLOXACIN
  • ALBUTEROL
  • IPRATROPIUM
  • FUROSEMIDE
  • METOPROLOL
  • SERTRALINE
  • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      You are recommended not to consume alcohol along with INSULIN HUMAN+ISOPHANE INSULIN to avoid unpleasant side effects. Alcohol may cause increased drowsiness.

    • Safety Warning

      Pregnancy

      safe if prescribed

      It is safe to use INSULIN HUMAN+ISOPHANE INSULIN during pregnancy if prescribed by the doctor. However, consult your doctor if you have any concerns regarding this.

    • Safety Warning

      Breast Feeding

      safe if prescribed

      It is safe to use INSULIN HUMAN+ISOPHANE INSULIN by breastfeeding mothers if prescribed by the doctor. However, consult your doctor if you have any concerns regarding this.

    • Safety Warning

      Driving

      caution

      INSULIN HUMAN+ISOPHANE INSULIN may cause drowsiness and hypoglycemia (low blood sugar). Therefore, drive only if you are alert.

    • Safety Warning

      Liver

      caution

      INSULIN HUMAN+ISOPHANE INSULIN should be taken with caution, especially if you have a history of liver disease. The dose may have to be adjusted by your doctor.

    • Safety Warning

      Kidney

      caution

      INSULIN HUMAN+ISOPHANE INSULIN should be taken with caution, especially if you have a history of kidney disease. The dose may have to be adjusted by your doctor.

    • Safety Warning

      Children

      safe if prescribed

      INSULIN HUMAN+ISOPHANE INSULIN can be given safely to children provided the dose has been prescribed by a child specialist.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Include foods rich in healthy carbohydrates and fibre, fruits, whole grains, and vegetables in your diet.
    • Try eating food at regular intervals. Do not skip meals. Also, try not to overeat.
    • Follow a healthy diet and walk for at least a few minutes to complement treatment with INSULIN HUMAN+ISOPHANE INSULIN.
    • Maintain a healthy weight by exercising regularly.
    • Rest properly, avoid stress by doing meditation or yoga.

    Special Advise

    If you experience any symptoms of hypoglycemia (fatigue, dizziness, confusion, heart palpitations, shakiness and anxiety), consult your doctor immediately.  

    Patients Concern

    Disease/Condition Glossary

    Diabetes: Diabetes is a chronic or lifelong disease that prevents the body from utilizing insulin properly. Insulin is the hormone that controls sugar levels in the blood. Diabetes is a condition in which blood glucose levels are above normal. It is of two types, namely: type-1 and type-2 diabetes. Type-1 diabetes is a condition in which the pancreas produces little or no insulin. Type-2 diabetes affects the way body processes the sugar. Symptoms of diabetes include lack of energy, tiredness, frequent urination, excess thirst, dry mouth, blurry vision, constant hunger, weight loss, and itchy skin.

    FAQs

    How does INSULIN HUMAN+ISOPHANE INSULIN work?

    INSULIN HUMAN+ISOPHANE INSULIN suppresses the production of sugar in the liver and facilitates the reuptake of sugar in the fat and muscle cells, thereby INSULIN HUMAN+ISOPHANE INSULIN ensures rapid and consistent sugar control.

    Does INSULIN HUMAN+ISOPHANE INSULIN cause hypoglycaemia (low blood glucose levels)?

    INSULIN HUMAN+ISOPHANE INSULIN may sometimes lower the blood glucose levels more than normal, leading to hypoglycaemia. Regularly monitor your blood sugar levels while taking INSULIN HUMAN+ISOPHANE INSULIN. Hypoglycaemia symptoms include headache, drowsiness, cold sweat, feeling sick, unusual tiredness or weakness, and visual disturbances.

    Can I stop taking INSULIN HUMAN+ISOPHANE INSULIN on my own?

    Do not stop taking INSULIN HUMAN+ISOPHANE INSULIN without consulting your doctor on your own as it may cause an increase in blood glucose levels. Continue taking INSULIN HUMAN+ISOPHANE INSULIN for as long as your doctor has prescribed it to you. Do not be reluctant to speak with your doctor if you experience any difficulty while taking INSULIN HUMAN+ISOPHANE INSULIN.

    How to prevent hypoglycaemia?

    Maintain a healthy diet by regular intake of carbohydrates such as bread and products containing starch and sugar. Eat your meals regularly, and do not exercise heavily for longer durations with an empty stomach.

    When does INSULIN HUMAN+ISOPHANE INSULIN cause hypoglycaemia?

    Hypoglycaemia may occur following prolonged or severe exercise, during illness, alcohol consumption, low food intake, or when INSULIN HUMAN+ISOPHANE INSULIN is taken along with other antidiabetic medicines.

    Available Medicines for

    INSULIN HUMAN+ISOPHANE INSULIN