OLMESARTAN+AMLODIPINE+CHLORTALIDONE belongs to a group of medications called 'anti-hypertensives primarily used to treat high blood pressure (hypertension). High blood pressure is a chronic (long-term) condition in which blood pressure is elevated persistently in higher than normal levels. This condition can also cause fluid retention, leading to peripheral oedema (swelling of legs and hands). If left untreated, this condition can increase the risk of heart-related diseases like heart attack, heart failure, stroke, irregular heartbeat, and other complications.
OLMESARTAN+AMLODIPINE+CHLORTALIDONE contains Olmesartan, Amlodipine, and Chlorthalidone. Olmesartan is an angiotensin-II receptor blocker (ARB). Angiotensin narrows the blood vessels increasing the blood pressure; therefore, blocking angiotensin can result in the widening of the narrowed blood vessels. Amlodipine is a calcium channel blocker. It acts by relaxing the blood vessels and improving the blood flow. Chlorthalidone is a diuretic or water pill that acts by expelling excess water and salt from the body. It helps in decreasing fluid accumulation and oedema.
You should take this medicine exactly as prescribed by the doctor. The common side-effects of OLMESARTAN+AMLODIPINE+CHLORTALIDONE are dizziness, flushing (reddening of the skin, especially the face), palpitation (pounding heartbeat), and low blood pressure. These side-effects are usually mild and resolve without requiring any medical attention. However, if any of these side-effects persist or get worse, inform your doctor immediately.
It is not recommended to take OLMESARTAN+AMLODIPINE+CHLORTALIDONE if you are allergic to any contents of it. It is not advised to use in patients who are allergic to sulfa drugs, are not able to urinate, and taking aliskiren (a blood pressure medicine), and have diabetes or kidney disease. It should not be used in children and adolescents under 18 years, pregnant women, and breastfeeding mothers. It should be used with caution in elderly people. Consumption of alcohol may increase the risk of side-effects. OLMESARTAN+AMLODIPINE+CHLORTALIDONE may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy.
Hypertension
OLMESARTAN+AMLODIPINE+CHLORTALIDONE is used to treat hypertension (high blood pressure) in adults. It works by lowering the body’s production of substances that could increase heart rate and also widens narrowed blood vessels. It allows the blood to flow more smoothly in the blood vessels. It also helps to reduce oedema or fluid overload. OLMESARTAN+AMLODIPINE+CHLORTALIDONE is a combination of medicines, so it shows greater efficacy and tolerability when compared to monotherapies. It helps to reduce serious complications of hypertension such as heart attack, stroke, and end-stage kidney disease.
Before taking OLMESARTAN+AMLODIPINE+CHLORTALIDONE, inform your doctor if you have liver or kidney disease, heart disease, chest pain, hyperkalemia (high levels of potassium in the blood), have been taking a low-salt diet, have a recent history of heart attack, gout, high cholesterol, and diabetes. OLMESARTAN+AMLODIPINE+CHLORTALIDONE may cause imbalances in the electrolyte levels. Do not get overheated in hot weather or by doing heavy exercise. Make sure to get hydrated by drinking fluids in these conditions. If you are also taking colesevelam (a drug that treats high cholesterol) along with OLMESARTAN+AMLODIPINE+CHLORTALIDONE, maintain a gap of at least 4 hours between the two medicines. Do not take any potassium supplements or salt substitutes unless advised by the doctor.
Drug-Drug Interactions: OLMESARTAN+AMLODIPINE+CHLORTALIDONE may interact with medicines that suppress the immune system (cyclosporine and tacrolimus), antidepressants (lithium), a medicine used to treat high cholesterol (simvastatin), steroid medicines, a medicine used to treat heart disease (digoxin), antidiabetic medicines (insulin), other oral antidiabetic medications, non-steroidal anti-inflammatory drugs (aspirin, ibuprofen, naproxen, diclofenac, and indomethacin, etc.).
Drug-Food Interactions: Avoid taking potassium supplements or salt substitutes while using OLMESARTAN+AMLODIPINE+CHLORTALIDONE.
Drug-Disease Interactions: OLMESARTAN+AMLODIPINE+CHLORTALIDONE should not be used in patients who are allergic to sulfa drugs and not able to urinate. It should be used with caution in patients with liver or kidney disease, heart disease, chest pain, hyperkalemia (high levels of potassium in the blood), a recent history of heart attack, gout, high cholesterol, and diabetes.
Alcohol should not be taken while using OLMESARTAN+AMLODIPINE+CHLORTALIDONE. It may worsen the health condition by increasing the risk of side-effects.
OLMESARTAN+AMLODIPINE+CHLORTALIDONE is a category C medicine and may cause harmful effects to the fetus or unborn baby. So, it is not recommended for use in pregnant women.
OLMESARTAN+AMLODIPINE+CHLORTALIDONE should be used with caution in breastfeeding mothers. Please consult your doctor before use.
OLMESARTAN+AMLODIPINE+CHLORTALIDONE may cause dizziness and affect your ability to drive. So, do not drive or operate heavy machinery if you feel dizzy.
OLMESARTAN+AMLODIPINE+CHLORTALIDONE should be used with caution in patients with liver diseases. The dose may have to be adjusted by the doctor as required.
OLMESARTAN+AMLODIPINE+CHLORTALIDONE should be used with extreme caution in patients with kidney diseases. The dose may have to be adjusted by the doctor as required.
OLMESARTAN+AMLODIPINE+CHLORTALIDONE is not recommended for use in children and adolescents below 18 years of age.
Hypertension: It is a chronic (long-term) condition in which blood pressure is elevated persistently at higher than normal levels. It occurs when the blood’s force against the wall of blood vessels is too high. This condition can cause chest pain (angina) and heart attack (when the blood supply to the heart is blocked). Additionally, high blood pressure also causes damage to the brain, kidneys, and eyes. The risk of high blood pressure complications increases with the following: obesity, smoking, diabetes, alcohol intake, lack of physical inactivity, stress, and kidney diseases.