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About TRANEXAMIC ACID+ETAMSYLATE

TRANEXAMIC ACID+ETAMSYLATE belongs to the class of medications called ‘Antihemorrhagic agents’ used to treat menorrhagia. Menorrhagia is a condition characterized by heavy or prolonged bleeding during menstrual periods. You are said to have menorrhagia if the bleeding is heavy to disrupt your daily activities, soaking one or more sanitary pads or tampons every hour for several consecutive hours, bleeding for more than a week, and experiencing symptoms such as fatigue, weakness, pale face, and shortness of breath. It is also used to stop postoperative hemorrhage (excessive bleeding after a surgical procedure), and local fibrinolysis (abnormal breakdown of blood clots)

TRANEXAMIC ACID+ETAMSYLATE is a combination of two medicines: Tranexamic acid and Etamsylate. Tranexamic acid belongs to the class of ‘anti-fibrinolytic agents’ which acts by regulating the breakdown of blood clots. It blocks the release and action of plasmin, an enzyme essential for the breakdown of clots present in the blood. Etamsylate is a hemostatic agent (prevents bleeding). It increases the ability of platelets to stick together (platelet adhesion) and form blood clots. It inhibits the action of chemical substances that cause the breakdown of platelets. These effects help to decrease abnormal bleeding.

You should take this medicine as prescribed by your doctor. TRANEXAMIC ACID+ETAMSYLATE may cause side-effects such as nausea, vomiting, diarrhea, stomach pain, fever, chills, rash, severe headache, back or joint pain, muscle pain, difficulty moving, and runny or stuffy nose. These side-effects usually go away without any treatment. If you develop any other serious side-effects such as vision problems while using TRANEXAMIC ACID+ETAMSYLATE, consult your doctor immediately.

Do not take TRANEXAMIC ACID+ETAMSYLATE if you are allergic to Tranexamic acid, Etamsylate, and any other ingredients present in it. Do not take this medicine if you have a history of kidney failure, thrombosis (formation of blood clots in the blood vessels), disseminated intravascular coagulation (a disease where blood clots form throughout your body), porphyria (a group of inherited blood disorders), and seizures (fits). Inform your doctor if you are taking birth control pills or fibrinolytic agents (medicines that dissolve blood clots). Also, inform your doctor if you are pregnant or breastfeeding.

Uses of TRANEXAMIC ACID+ETAMSYLATE

Menorrhagia, Postoperative hemorrhage (excessive bleeding after a surgical procedure), and local fibrinolysis (abnormal breakdown of blood clots)

Medicinal Benefits

TRANEXAMIC ACID+ETAMSYLATE is a combination of two medicines: Tranexamic acid and Etamsylate. Tranexamic acid belongs to the class of ‘anti-fibrinolytic agents’. It acts by regulating the breakdown of blood clots in the body. It blocks the release and action of plasmin, an enzyme essential for the breakdown of clots present in the blood. Etamsylate increases the ability of platelets to stick together (platelet adhesion) and form blood clots. It inhibits the action of chemical substances that cause the breakdown of platelets. This effect helps to slow down the abnormal bleeding.

Directions for Use

Swallow TRANEXAMIC ACID+ETAMSYLATE as a whole with a glass of water. Do not break, chew, or crush the tablet/capsule. The dose and duration are prescribed by the doctor based on your condition.

Storage

Store in a cool and dry place away from sunlight

Side Effects of TRANEXAMIC ACID+ETAMSYLATE

  • Nausea (feeling sick)
  • Vomiting (being sick)
  • Diarrhea
  • Stomach pain
  • Swelling of face, lips, eyelids, tongue, hands, and feet
  • Dizziness
  • Headache
  • Chills
  • Fever
  • Rash
  • Pale skin
  • Severe headache
  • Back or joint pain
  • Muscle pain
  • Difficulty moving
  • Difficulty breathing
  • Runny or stuffy nose

In-Depth Precautions and Warning

Drug Warnings

You should not take this medicine until the underlying cause of menorrhagia is established. Inform your doctor if you are using birth control pills, including the patch, vaginal ring, and an intrauterine device (IUD), as there is a risk of deep vein thrombosis (a condition in which blood clot is formed in the deeper vein, mostly legs). Inform your doctor if you are using fibrinolytic agents (drugs that break blood clots) as they may interfere with the activity of TRANEXAMIC ACID+ETAMSYLATE.

Drug Interactions

Drug-drug interactions: TRANEXAMIC ACID+ETAMSYLATE may interact with birth control pills, fibrinolytic drugs (streptokinase, urokinase, reteplase, and alteplase, etc.), an antipsychotic drug (chlorpromazine), and a drug used to treat blood cancer (tretinoin), and progestins (levonorgestrel).

Drug-food interactions: Alcohol consumption may increase the risk of side-effects.

Drug-disease interactions: TRANEXAMIC ACID+ETAMSYLATE should not be used in patients with a history of thrombosis (formation of blood clots in the blood vessels), disseminated intravascular coagulation (a disease where blood clots form throughout your body), porphyria (a group of inherited blood disorders), bleeding in the brain, seizures (fits), liver disease, and kidney failure.

Drug-Drug Interactions Checker List:

  • STREPTOKINASE
  • UROKINASE
  • RETEPLASE
  • ALTEPLASE
  • CHLORPROMAZINE
  • TRETINOIN
  • LEVONORGESTREL
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      Consumption of alcohol may worsen your health condition as it may increase the risk of side-effects.

    • Safety Warning

      Pregnancy

      caution

      TRANEXAMIC ACID+ETAMSYLATE is a category B medicine and may not show any toxic effects to the fetus. However, it should be used with caution in pregnant women to avoid unwanted risks and only when prescribed by a doctor.

    • Safety Warning

      Breast Feeding

      caution

      TRANEXAMIC ACID+ETAMSYLATE may get secreted in breast milk in very low amounts. However, it should be used with caution in breastfeeding mothers to avoid unwanted risks and only when prescribed by a doctor.

    • Safety Warning

      Driving

      safe if prescribed

      TRANEXAMIC ACID+ETAMSYLATE may not affect your ability to drive.

    • Safety Warning

      Liver

      safe if prescribed

      TRANEXAMIC ACID+ETAMSYLATE is probably safe in patients with liver diseases. Consult your doctor for further advice.

    • Safety Warning

      Kidney

      caution

      TRANEXAMIC ACID+ETAMSYLATE should be used with caution in patients with kidney diseases. The dose may have to be adjusted by your doctor.

    • Safety Warning

      Children

      unsafe

      TRANEXAMIC ACID+ETAMSYLATE is not recommended for use in children.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Maintain a healthy weight. Stay physically active.
    • Consume fresh fruits and vegetables. Avoid spicy, salty, and deep-fried foods. Eating healthy can help you to recover faster.
    • Avoid tea, coffee, and cold drinks.
    • Drink plenty of fluids to stay hydrated. Fluids are necessary to maintain blood flow in your body.
    • Avoid the intake of alcoholic beverages as it can make you dehydrated and also can affect your sleep.
    • Avoid physical and psychological stress.
    • Relax in a hot bath, use a heating pad, or take herbal teas to reduce stomach cramps. Massage therapy can also help to reduce cramps.

    Special Advise

    • TRANEXAMIC ACID+ETAMSYLATE may cause an increase in body temperature in some patients. Contact your doctor immediately if you experience a high fever.
    • TRANEXAMIC ACID+ETAMSYLATE is not recommended for use in patients with a history of any disease where the eye's blood vessels are obstructed due to clot formation.

    Patients Concern

    Disease/Condition Glossary

    Menorrhagia: Menorrhagia is heavy bleeding during periods. Symptoms include heavy bleeding that disrupts your daily activities, soaking one or more sanitary pads or tampons every hour for several consecutive hours, bleeding for more than a week, and experiencing anemia symptoms such as fatigue, weakness, pale face, and shortness of breath. It can occur various causes such as hormonal imbalance, ovarian failure, uterine fibroids (benign tumors in the uterus), and cancer of the uterus or cervix.

    FAQs

    How does TRANEXAMIC ACID+ETAMSYLATE work?

    TRANEXAMIC ACID+ETAMSYLATE is a combination of two medicines: Tranexamic acid and Etamsylate. Etamsylate acts by increasing the ability to stick together and form blood clots, whereas tranexamic acid prevents the breakdown of the clots. These effects helps to reduce the heavy bleeding during periods.

    Does TRANEXAMIC ACID+ETAMSYLATE stop periods?

    TRANEXAMIC ACID+ETAMSYLATE is used to control heavy bleeding during periods and doesn’t stop periods. However, do not use this medicine for any indication without consulting your doctor.

    In which conditions should I avoid taking TRANEXAMIC ACID+ETAMSYLATE?

    Do not take this medicine if you are previously diagnosed with kidney failure, thrombosis (formation of blood clots in the blood vessels), disseminated intravascular coagulation (a disease where blood clots form throughout your body), porphyria (a group of inherited blood disorders), and seizures (fits).

    I am using birth control pills, can I take TRANEXAMIC ACID+ETAMSYLATE?

    TRANEXAMIC ACID+ETAMSYLATE should not be taken with birth control pills, including the vaginal ring, intrauterine device, and the patch, as there is a risk of ‘deep vein thrombosis (formation of a blood clot in the deeper vein, mostly legs). So, inform your doctor before taking TRANEXAMIC ACID+ETAMSYLATE if you are taking any birth control pills.

    What are the common side-effects of TRANEXAMIC ACID+ETAMSYLATE?

    The common side-effects of TRANEXAMIC ACID+ETAMSYLATE are nausea, vomiting, diarrhea, stomach pain, fever, chills, rash, severe headache, back or joint pain, muscle pain, difficulty moving, and runny or stuffy nose. These side-effects are usually temporary and don’t require any treatment.

    Does TRANEXAMIC ACID+ETAMSYLATE affect fertility?

    TRANEXAMIC ACID+ETAMSYLATE may not affect your fertility. It is only used to stop abnormal bleeding during heavy periods. However, if you notice any unwanted effects while using this medicine, inform your doctor immediately.

    How can I reduce period cramps?

    Drinking hot water can reduce period cramps by increasing the blood flow throughout the body. Soak in a hot bath or using a heating pad on the belly or back can reduce cramps. It also helps to relax the muscles.

    Available Medicines for

    TRANEXAMIC ACID+ETAMSYLATE