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Buprigesic 10mcg/Hr Transdermal Patch is primarily used to treat pain. It contains 'Buprenorphine', an opioid partial agonist-antagonist. It works by blocking a chemical messenger in the brain that is responsible for causing pain. This provides pain relief by acting on specific receptors in the brain. Common side effects of Buprigesic 10mcg/Hr Transdermal Patch are drowsiness, dry mouth, vomiting, blurred vision, constipation, application site reactions, dizziness, or tiredness.

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Written By Lakshmithulasi Yarragunta ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Drug-Drug Interactions

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Drug-Drug Interactions: Buprigesic 10mcg/Hr Transdermal Patch may have interaction with benzodiazepines (diazepam, temazepam ), pain killers (pentazocine, nalbuphine, codeine, dihydrocodeine, methadone, morphine), anti-depressants (moclobemide, tranylcypromine, citalopram, escitalopram, fluoxetine, fluvoxamine, paroxetine, sertraline, duloxetine, venlafaxine, amitriptyline, doxepin, trimipramine), antihistamine (promethazine, chlorphenamine), blood thinners (warfarin), anti-anxiety drugs (alprazolam), fits related medicines (carbamazepine), medicines used to prevent nausea (ondansetron), antifungal drugs (ketoconazole), antibiotic (ciprofloxacin, erythromycin), anticancer drugs (ceritinib, lapatinib), immunosuppressants (fingolimod), antipsychotics (droperidol), and HIV/AIDS drugs (saquinavir).

Drug-Food Interactions: Buprigesic 10mcg/Hr Transdermal Patch may interact with grapefruit juice. Therefore, avoid grapefruit juice intake with Buprigesic 10mcg/Hr Transdermal Patch, as it may increase Buprigesic 10mcg/Hr Transdermal Patch levels in the body. Also, avoid St. John's wort (an antidepressant plant) and alcohol consumption while using Buprigesic 10mcg/Hr Transdermal Patch, as they may increase the risk of adverse effects such as drowsiness, dizziness, and difficulty concentrating.

Drug-Disease Interactions: People with asthma or any other breathing problems, kidney problems, liver problems, head injury or brain disease, low blood pressure, urinary disorders (especially linked to enlarged prostate), thyroid problems, adrenocortical disorder (Addison’s disease), depression should consult a doctor before using Buprigesic 10mcg/Hr Transdermal Patch.

BuprenorphineAlvimopan
Critical

Drug-Drug Interactions

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BuprenorphineAlvimopan
Critical
How does the drug interact with Buprigesic 10mcg/Hr Transdermal Patch:
Using alvimopan together with Buprigesic 10mcg/Hr Transdermal Patch can cause side effects (abdominal pain, nausea, vomiting, and diarrhea).

How to manage the interaction:
Taking Alvimopan with Buprigesic 10mcg/Hr Transdermal Patch is not recommended, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
How does the drug interact with Buprigesic 10mcg/Hr Transdermal Patch:
Taking Ziprasidone with Buprigesic 10mcg/Hr Transdermal Patch can increase the risk of serious side effects.

How to manage the interaction:
Taking Ziprasidone with Buprigesic 10mcg/Hr Transdermal Patch is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, drowsiness, difficulty concentrating, and impairment in judgment. Do not discontinue any medications without consulting a doctor.
BuprenorphineParamethadione
Severe
How does the drug interact with Buprigesic 10mcg/Hr Transdermal Patch:
Using Buprigesic 10mcg/Hr Transdermal Patch together with Paramethadione can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although there is a possible interaction between Paramethadione and Buprigesic 10mcg/Hr Transdermal Patch, you can take these medicines together if prescribed by a doctor. Doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Buprigesic 10mcg/Hr Transdermal Patch:
Using Buprigesic 10mcg/Hr Transdermal Patch together with Nabilone can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Nabilone and Buprigesic 10mcg/Hr Transdermal Patch together can cause an interaction, it can be taken if a doctor has suggested it. It's important to keep an eye on your health and be aware of any changes. Doctor can recommend other options that won't cause any problems. If you notice any symptoms like feeling very tired or having trouble breathing, make sure to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
BuprenorphinePethidine
Severe
How does the drug interact with Buprigesic 10mcg/Hr Transdermal Patch:
Using Buprigesic 10mcg/Hr Transdermal Patch together with Pethidine can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Pethidine and Buprigesic 10mcg/Hr Transdermal Patch together can cause an interaction, it can be taken if a doctor has suggested it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Buprigesic 10mcg/Hr Transdermal Patch:
Taking Buprigesic 10mcg/Hr Transdermal Patch along with carbamazepine may increase the risk of side effects such as breathing problems.

How to manage the interaction:
Although taking carbamazepine and Buprigesic 10mcg/Hr Transdermal Patch together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience watery eyes, runny nose, sneezing, yawning, excessive sweating, goose bumps, fever, chills, flushing, restlessness, anxiety, depression, rapid heart beat, body aches, abdominal cramping, loss of appetite, nausea, vomiting, diarrhea, and weight loss contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Buprigesic 10mcg/Hr Transdermal Patch:
When Buprigesic 10mcg/Hr Transdermal Patch is used with diazepam, it may lead to significant adverse effects such as respiratory difficulties.

How to manage the interaction:
Concomitant administration of Buprigesic 10mcg/Hr Transdermal Patch alongside diazepam can result in an interaction, it can be taken if a doctor has advised it. You should avoid driving or operating hazardous machinery until you're aware of how these drugs affect you. Do not discontinue any medications without consulting a doctor.
BuprenorphineSuvorexant
Severe
How does the drug interact with Buprigesic 10mcg/Hr Transdermal Patch:
When Buprigesic 10mcg/Hr Transdermal Patch is used with suvorexant, it may lead to significant adverse effects such as respiratory difficulties, unconsciousness.

How to manage the interaction:
Concomitant administration of Buprigesic 10mcg/Hr Transdermal Patch alongside suvorexant can result in an interaction, it can be taken if a doctor has advised it. Do not exceed the doses, frequency, or duration of usage advised by a doctor. You should avoid driving or operating hazardous machinery until you're aware of how these medications effect you. Do not discontinue any medications without consulting a doctor.
BuprenorphineAnagrelide
Severe
How does the drug interact with Buprigesic 10mcg/Hr Transdermal Patch:
Taking Buprigesic 10mcg/Hr Transdermal Patch with anagrelide increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Concomitant administration of Buprigesic 10mcg/Hr Transdermal Patch with anagrelide can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, get medical help immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Buprigesic 10mcg/Hr Transdermal Patch:
When Buprigesic 10mcg/Hr Transdermal Patch is used with aripiprazole, it may possibly lead to significant adverse effects such as respiratory distress, unconsciousness.

How to manage the interaction:
Co-administration of Buprigesic 10mcg/Hr Transdermal Patch alongside aripiprazole can result in an interaction, it can be taken if a doctor has advised it. Do not exceed the doses, frequency, or duration of usage advised by a doctor. You should avoid driving or operating hazardous machinery. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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