VOTRIENT 200MG TABLET 30'S

Out of stock
SKU
VOT0012
₹7,903.00 Inclusive of all taxes
Manufacturer : GLA-GLAXO SMITHKLINE
Composition : PAZOPANIB-200MG
Dose Form : TABLET
Description : VOTRIENT 200MG TAB 30'S
Route Of Administration : ORAL
Pack : 1

Drug Ingredient Information

PAZOPANIB-200MG

PAZOPANIB

Information for patients
Drug Information PAZOPANIB is a prescription medicine used to treat people with: • advanced renal cell cancer (RCC) • advanced soft tissue sarcoma (STS) who have received chemotherapy in the past It is not known if PAZOPANIB is effective in treating certain soft tissue sarcomas or certain gastrointestinal tumors. 36 It is not known if PAZOPANIB is safe and effective in children under 18 years of age.
Drug Alert
Alert PAZOPANIB can cause serious liver problems including death. Your healthcare provider will do blood tests to check your liver before you start and while you take PAZOPANIB.
Before Consuming the Medicine
Avoid Drug • yellowing of your skin or the whites of your eyes (jaundice) • dark urine • tiredness • nausea or vomiting • loss of appetite • pain on the right side of your stomach area (abdomen) • bruise easily Your healthcare provider may need to prescribe a lower dose of PAZOPANIB for you or tell you to stop taking PAZOPANIB if you develop liver problems during treatment
Drug Special Care • have or had liver problems. You may need a lower dose of PAZOPANIB or your healthcare provider may prescribe a different medicine to treat your advanced renal cell cancer or advanced soft tissue sarcoma. • have high blood pressure • have heart problems or an irregular heartbeat including QT prolongation • have a history of a stroke • have headaches, seizures, or vision problems • have coughed up blood in the last 6 months • had bleeding of your stomach or intestines in the last 6 months • have a history of a tear (perforation) in your stomach or intestine, or an abnormal connection between two parts of your gastrointestinal tract (fistula) • have had blood clots in a vein or in the lung • have thyroid problems • had recent surgery (within the last 7 days) or are going to have surgery 54 • have any other medical conditions • are pregnant or plan to become pregnant. PAZOPANIB can harm your unborn baby. You should not become pregnant while you are taking PAZOPANIB. • are breastfeeding or plan to breastfeed. It is not known if PAZOPANIB passes into your breast milk. You and your healthcare provider should decide if you will 59 take PAZOPANIB or breastfeed. You should not do both.
Drug Drug Interactions • take medicines that can affect how your liver enzymes work such as: • certain antibiotics (used to treat infections) • certain medicines used to treat HIV • certain medicines used to treat depression • medicines used to treat irregular heart beats • take a medicine that contains simvastatin to treat high cholesterol levels • drink grapefruit juice Ask your healthcare provider if you are not sure if your medicine is one that is listed above. Know the medicines you take. Keep a list of them and show it to your healthcare provider and pharmacist when you get a new medicine. prescription and non-prescription medicines, vitamins, and herbal supplements. PAZOPANIB may affect the way other medicines work and other medicines may affect how PAZOPANIB works.
Drug Pregnancy Interaction no data available
Drug Breast feeding Interaction no data available
Drug Machinery Interaction no data available
Drug More Information • irregular or fast heartbeat or fainting • heart failure. This is a condition where your heart does not pump as well as it should and may cause you to have shortness of breath. • heart attack or stroke. Heart attack and stroke can happen with PAZOPANIB and may cause death. Symptoms may include: chest pain or pressure, pain in your arms, back, neck or jaw, shortness of breath, numbness or weakness on one side of your body, trouble talking, headache, or dizziness. • blood clots. Blood clots may form in a vein, especially in your legs (deep vein thrombosis or DVT). Pieces of a blood clot may travel to your lungs (pulmonary embolism). This may be life threatening and cause death. Symptoms may include: new chest pain, trouble breathing or shortness of breath that starts suddenly, leg pain, and swelling of the arms and hands, or 116 legs and feet, a cool or pale arm or leg. • bleeding problems. These bleeding problems may be severe and cause death. Symptoms may include: unusual bleeding, bruising, wounds that do not heal. • tear in your stomach or intestinal wall (perforation) or an abnormal connection between two parts of your gastrointestinal tract (fistula).
How to take the Medicine
Consumption Info no data available
Drug quanitty no data available
Drug Dose • Take PAZOPANIB exactly as your healthcare provider tells you. Your healthcare provider will tell you how much PAZOPANIB to take. • Your healthcare provider may change your dose. • Take PAZOPANIB on an empty stomach, at least 1 hour before or 2 hours after food. • Do not crush PAZOPANIB tablets. • Do not eat grapefruit or drink grapefruit juice during treatment with PAZOPANIB. Grapefruit products may increase the amount of PAZOPANIB in your body. • If you miss a dose, take it as soon as you remember. Do not take it if it is close (within 12 hours) to your next dose. Just take the next dose at your regular time. Do not take more than 1 dose of PAZOPANIB at a time. • Your healthcare provider will test your urine, blood, and heart before you start and while you take PAZOPANIB. • Tell your healthcare provider if you plan to have surgery while taking PAZOPANIB. You will need to stop taking PAZOPANIB at least 7 days before surgery because PAZOPANIB may affect healing after surgery.
Excess Drug Consumption Dail 1066. OR Contact doctor immediately
Forgot Drug Consumption Contact Your doctor
Stop Drug Consumption Do not stop the drug untill your doctor says you to do so.
Possible Side Effects
General Information • thyroid problems. Your healthcare provider should check you for this during treatment with PAZOPANIB. • protein in your urine. Your healthcare provider will check you for this problem. If there is too much protein in your urine, your healthcare provider may tell you to stop taking PAZOPANIB. • serious infections. Serious infections can happen with PAZOPANIB and can cause death.Symptoms of an infection may include: fever, cold symptoms, such as runny nose or sore throat that do not go away, flu symptoms, such as cough, tiredness, and body aches, pain when urinating, cuts, scrapes or wounds that 149 are red, warm, swollen or painful. • collapsed lung (pneumothorax). A collapsed lung can happen with PAZOPANIB. Air may get trapped in the space between your lung and chest wall. This may cause you to have shortness of breath.
Common Drug Side Effects • diarrhea • change in hair color • nausea or vomiting • loss of appetite
Rare Drug Side Effects • feeling tired • decreased weight • tumor pain • muscle or bone pain • headache • taste changes • trouble breathing • change in skin color
Very Rare Drug Side Effects no data available
Drug Side Effects Symptoms • irregular or fast heartbeat or fainting • heart failure. This is a condition where your heart does not pump as well as it should and may cause you to have shortness of breath. • heart attack or stroke. Heart attack and stroke can happen with PAZOPANIB and may cause death. Symptoms may include: chest pain or pressure, pain in your arms, back, neck or jaw, shortness of breath, numbness or weakness on one side of your body, trouble talking, headache, or dizziness. • blood clots. Blood clots may form in a vein, especially in your legs (deep vein thrombosis or DVT). Pieces of a blood clot may travel to your lungs (pulmonary embolism). This may be life threatening and cause death. Symptoms may include: new chest pain, trouble breathing or shortness of breath that starts suddenly, leg pain, and swelling of the arms and hands, or 116 legs and feet, a cool or pale arm or leg. • bleeding problems. These bleeding problems may be severe and cause death. Symptoms may include: unusual bleeding, bruising, wounds that do not heal. • tear in your stomach or intestinal wall (perforation) or an abnormal connection between two parts of your gastrointestinal tract (fistula). Symptoms may include: pain, swelling in your stomach-area, vomiting blood, and black sticky stools. • Reversible Posterior Leukoencephalopathy (RPLS). RPLS is a condition that can happen while taking PAZOPANIB that may cause death. Symptoms may include: headaches, seizures, lack of energy, confusion, high blood pressure, blindness or changes in vision, and problems thinking. • high blood pressure. High blood pressure can happen with PAZOPANIB, including a sudden and severe rise in blood pressure which may be life threatening. These blood pressure increases usually happen in the first several months of treatment. Your blood pressure should be well controlled before you start taking PAZOPANIB. Your healthcare provider should begin checking your blood pressure within 1 week of you starting PAZOPANIB and often during treatment to make sure that your blood pressure is well controlled.
How to Store the Medicine
How to Store the Medicine Store PAZOPANIB at room temperature between 68oF and 77oF (20oC to 25oC). Keep PAZOPANIB and all medicines out of the reach of children. General information about the safe and effective use of PAZOPANIB. Medicines are sometimes prescribed for purposes other than those listed in a Medication Guide. Do not use PAZOPANIB for a condition for which it was not prescribed. Do not give PAZOPANIB to other people even if they have the same symptoms that you have. It may harm them. This Medication Guide summarizes the most important information about PAZOPANIB. If you would like more information, talk with your healthcare provider. You can ask your pharmacist or healthcare provider for information about PAZOPANIB that is written for healthcare professionals. For more information, go to

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