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Celrixafor Injection Substitute

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Verified Ingredients and Effects

Composition:

PLERIXAFOR-24MG

Uses:

<p>Celrixafor Injection is used in the treatment of Multiple Myeloma and Non-Hodgkin’s Disease. The detailed uses of Celrixafor Injection are as follows:</p><ul><li><strong>Stem cell mobilization:</strong> Celrixafor Injection is used in combination with granulocyte-colony stimulating factor (G-CSF) to help the bone marrow release hematopoietic stem cells into the bloodstream. These cells are then collected for autologous stem cell transplantation, a procedure often used in cancer treatment.</li><li><strong>Treatment of certain cancers:</strong> Celrixafor Injection is indicated for patients with non-Hodgkin’s lymphoma and multiple myeloma who are undergoing stem cell transplantation. By increasing the number of stem cells in the blood, it improves the success rate of the transplant.</li></ul>

Medicinal Benefits:

Celrixafor Injection contains Plerixafor, which belongs to the hemopoietic stem cell mobilizer class or drugs. It works by binding to the chemokine receptor CXCR4 and inhibiting its cognate ligand CXCL12 binding. This mobilizes hematopoietic stem cells to the peripheral blood for collection and subsequent autologous transplantation in cancer patients.

FAQs

Celrixafor Injection is used to treat Multiple Myeloma, Non-Hodgkin’s Disease.

Celrixafor Injection contains Plerixafor, which works by binding to the chemokine receptor CXCR4 and inhibits the binding of its cognate ligand CXCL12.

Celrixafor Injection may cause tumor cell mobilization and haematological effects such as increased lymphocytes, decreased platelet count, and splenic rupture in some patients. Hence, inform your oncologist about your complete medical history, including current medication, to rule out any side effects/interactions.

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